Works matching DE "BCL-2 proteins"

Results: 1748

Development of a clinical prediction model for sensitivity to combination therapy of Bcl-2 inhibitors and hypomethylating agents in elderly/unfit patients with acute myeloid leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02612-1

By:

Du, Yufeng;
Li, Chunhong;
Chen, Yonghong;
Xie, Fang;
Yan, Jinsong

Publication type:

Article

The Effects of ThymusCaramanicus Jalas Extract and Its Main Constituent Carvacrol Against Cisplatin-Induced Nephrotoxicity in Mice.

Published in:

IJ Pharmaceutical Research (IJPR), 2024, v. 23, n. 1, p. 1, doi. 10.5812/ijpr-140212

By:

Hassanshahi, Amin;
Kaeedi, Ayat;
Rahmani, Mohammad Reza;
Hassanshahi, Jalal

Publication type:

Article

Curcumin-Etoposide Synergy: Unveiling the Molecular Mechanisms of Enhanced Apoptosis and Chemoresistance Attenuation in Breast Cancer.

Published in:

IJ Pharmaceutical Research (IJPR), 2024, v. 23, n. 1, p. 1, doi. 10.5812/ijpr-150978

By:

Asl, Bahar Jaberian;
Afarin, Reza;
Hatami, Mahdi;
Madiseh, Amineh Dehghani;
Roshanazadeh, Mohammadreza;
Rashidi, Mojtaba

Publication type:

Article

Augmenting the Anti‐Leukemic Activity of the BCL‐2 Inhibitor Venetoclax Through Its Transformation Into Polypharmacologic Dual BCL‐2/HDAC1 and Dual BCL‐2/HDAC6 Inhibitors.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70084

By:

Chan, Alexandria M.;
Eberly, Christian;
Drennen, Brandon;
Goodis, Christopher C.;
Wuyts, Zoe;
Civin, Curt I.;
Fletcher, Steven

Publication type:

Article

Estudio de un nuevo tratamiento contra la leucemia linfoblástica aguda tipo T.

Published in:

Acta Pediatrica de Mexico, 2025, v. 46, p. S35, doi. 10.18233/apm.v46i2.2814

By:

Antonio Flores-López, Luis;
Jaime Matadamas-Ortiz, Elías;
Enríquez-Flores, Sergio;
de la Mora-de la Mora, Ignacio;
García-Torres, Itzhel;
Paola González-Loza, Fernanda

Publication type:

Article

Luteolin Abates Ifosfamide-Induced Nephrotoxicity by Downregulating Renal Oxidative DNA Damage, Inflammation, and Apoptosis in Experimental Rats.

Published in:

International Journal of Morphology, 2025, v. 43, n. 2, p. 422

By:

Abubakr, Sara;
Ibrahim, Mohie Mahmoud;
Taha, Medhat;
Hussin, Emadeldeen;
Hendawy, Mahmoud;
El-Hay, Reem Ibrahim Abd.;
Elmetwally, Ahmed Abdel-monem;
Abdelkareem, Mona A.;
Farage, Amira E.;
Baokbah, Tourki A. S.;
Rabei, Mohammed R.;
Faheem, Ahmed Mohsen;
Badawy, Alaa. M.

Publication type:

Article

Magnesium isoglycyrrhizinate ameliorates isoproterenol-induced myocardial remodeling in mice by regulating oxidative stress and apoptosis via the PI3K/AKT1 signaling pathway.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2025, v. 34, n. 4, p. 321, doi. 10.5246/jcps.2025.04.024

By:

Xingyu Zhou;
Dan Fu1;
Saige Sun;
Qiuyan Liu;
Longxing Liu;
Jia Shi;
Zijie Ge;
Yu Ma;
Yilin He;
Li Xu;
Kai Qian

Publication type:

Article

片仔癀在对乙酰氨基酚所致肝损伤中的保护作用及其机制.

Published in:

Journal of Jilin University (Medicine Edition), 2025, v. 51, n. 1, p. 105, doi. 10.13481/j.1671-587X.20250113

By:

张潮鹤;
张昕玮;
王相峰

Publication type:

Article

积雪草酸通过 Nrf2/HO-1 信号通路对脂多糖诱导大鼠海马神经元损伤的改善作用.

Published in:

Journal of Jilin University (Medicine Edition), 2025, v. 51, n. 1, p. 85, doi. 10.13481/j.1671-587X.20250111

By:

白燕燕;
周禹彤;
隋海娟;
刘卓

Publication type:

Article

Yes 相关蛋白对人宫颈癌 SiHa 细胞生物学行为的影响.

Published in:

Journal of Jilin University (Medicine Edition), 2025, v. 51, n. 1, p. 68, doi. 10.13481/j.1671-587X.20250109

By:

赵芳;
李珍玲;
朴丽花;
韩龙哲;
崔银姬;
权春姬;
金雪梅

Publication type:

Article

Targeting BCL2 in Waldenström macroglobulinemia: from biology to treatment management.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1564869

By:

Kalafati, Eleni;
Kastritis, Efstathios;
Bagratuni, Tina

Publication type:

Article

Expressions and localizations of Bax/Bcl-2 proteins during metamorphosis of Pelophylax ridibundus.

Published in:

Biotechnic & Histochemistry, 2014, v. 89, n. 1, p. 41, doi. 10.3109/10520295.2013.817607

By:

Başımoğlu Koca, Y;
Koca, S

Publication type:

Article

Design, Synthesis, and Evaluation of BCL‐2 Targeting PROTACs.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 45, p. 1, doi. 10.1002/chem.202400430

By:

Bricelj, Aleša;
Dora Ng, Yuen Lam;
Gobec, Martina;
Kuchta, Robert;
Hu, Wanyi;
Javornik, Špela;
Rožič, Miha;
Gütschow, Michael;
Zheng, Guangrong;
Krönke, Jan;
Steinebach, Christian;
Sosič, Izidor

Publication type:

Article

MicroRNA miR-212 regulates PDCD4 to attenuate Aβ25–35-induced neurotoxicity via PI3K/AKT signaling pathway in Alzheimer's disease.

Published in:

Biotechnology Letters, 2020, v. 42, n. 9, p. 1789, doi. 10.1007/s10529-020-02915-z

By:

Wang, Yanjun;
Chang, Qing

Publication type:

Article

Nephroblastoma Overexpressed Protein (NOV/CCN3) Elevated Expression of Inflammation Regulators in a Model of Sepsis-Induced Lung Injury.

Published in:

Bulletin of Experimental Biology & Medicine, 2025, v. 178, n. 4, p. 453, doi. 10.1007/s10517-025-06355-5

By:

Zhu, H.;
Liu, L.;
Yang, M.;
Zhu, X.;
Cai, J.;
Huang, H.

Publication type:

Article

The Effect of Inactivating Heterozygous Mutation in NBS1 Gene on DNA Damage and Repair Markers and Apoptosis Markers in Mice.

Published in:

Bulletin of Experimental Biology & Medicine, 2023, v. 175, n. 2, p. 234, doi. 10.1007/s10517-023-05841-y

By:

Yurova, M. N.;
Golubev, A. G.;
Aleksakhina, S. N.;
Fedoros, E. I.;
Tumanyan, I. A.;
Otradnova, E. A.;
Soloviev, I. V.;
Sergiev, P. V.;
Imyanitov, E. N.

Publication type:

Article

Changes in the Expression of Pluripotency Factor Oct-4 and Intensity of Apoptosis in the Uterus during Spontaneous and Immune-Dependent Abortions in Mice.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 172, n. 6, p. 765, doi. 10.1007/s10517-022-05474-7

By:

Artem'eva, K. A.;
Stepanova, I. I.;
Bogdanova, I. M.;
Boltovskaya, M. N.;
Yaglova, N. V.;
Obernikhin, S. V.;
Ponomarenko, E. A.

Publication type:

Article

Expression of Bax and Bcl-2 Proteins in Left-Ventricular Cardiomyocytes in Wistar-Kyoto and SHR Rats with Insulin-Dependent Diabetes Mellitus.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 171, n. 5, p. 576, doi. 10.1007/s10517-021-05272-7

By:

Sklifasovskaya, A. P.;
Blagonravov, M. L.;
Ryabinina, A. Yu.;
Azova, M. M.;
Goryachev, V. A.

Publication type:

Article

Effect of Melatonin on Expression of Apoptosis Regulator Proteins Bcl-2 and Bad in Ovarian Follicular Apparatus after High Temperature Exposure.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 170, n. 5, p. 598, doi. 10.1007/s10517-021-05114-6

By:

Michurina, S. V.;
Kolesnikov, S. I.;
Ishchenko, I. Yu.;
Bochkareva, A. L.;
Arkhipov, S. A.

Publication type:

Article

Expression of Apoptosis Regulator Proteins Bcl-2 and Bad in Rat Ovarian Follicular Apparatus during Recovery after Extreme Hypothermia.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 168, n. 2, p. 205, doi. 10.1007/s10517-019-04675-x

By:

Michurina, S. V.;
Kolesnikov, S. I.;
Bochkareva, A. L.;
Ishchenko, I. Yu.;
Arkhipov, S. A.

Publication type:

Article

Effect of Linagliptin on the Ratio of Apoptosis Regulators in the Model of Non-Alcoholic Fatty Liver Disease in db/db Mice.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 167, n. 2, p. 210, doi. 10.1007/s10517-019-04493-1

By:

Michurina, S. V.;
Cherepanova, M. A.;
Ishchenko, I. Yu.;
Arkhipov, S. A.;
Klimontov, V. V.;
Zav'yalov, E. L.

Publication type:

Article

Effect of Linagliptin on the Ratio of Apoptosis Regulators in the Model of Non-Alcoholic Fatty Liver Disease in db/db Mice.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 210, doi. 10.1007/s10517-019-04493-1

By:

Michurina, S. V.;
Cherepanova, M. A.;
Ishchenko, I. Yu.;
Arkhipov, S. A.;
Klimontov, V. V.;
Zav'yalov, E. L.

Publication type:

Article

Effects of Experimental Coma on the Expression of Bcl-2 Protein and Caspases 3 and 9 in Rat Brain.

Published in:

Bulletin of Experimental Biology & Medicine, 2015, v. 160, n. 2, p. 216, doi. 10.1007/s10517-015-3132-1

By:

Shvetsov, A.;
Dyuzhikova, N.;
Savenko, Yu.;
Batotsyrenova, E.;
Kashuro, V.

Publication type:

Article

Tonkinensine B induces apoptosis through mitochondrial dysfunction and inactivation of the PI3K/AKT pathway in triple-negative breast cancer cells.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 10, p. 1397, doi. 10.1093/jpp/rgab108

By:

Sun, Xuanrong;
Zhang, Tianwei;
Cai, Yue;
Yang, Ke;
Peng, Tingting;
Liu, Renhao;
Li, Xing-Nuo

Publication type:

Article

Natural polyphenols prevent indomethacin‐induced and diclofenac‐induced Caco‐2 cell death by reducing endoplasmic reticulum stress regardless of their direct reactive oxygen species scavenging capacity.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 4, p. 583, doi. 10.1111/jphp.13227

By:

Boonyong, Cherdsak;
Vardhanabhuti, Nontima;
Jianmongkol, Suree

Publication type:

Article

Meriolin1 induces cell cycle arrest, apoptosis, autophagy and targeting the Akt/MAPKs pathways in human neuroblastoma SH‐SY5Y cells.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 4, p. 561, doi. 10.1111/jphp.13224

By:

Su, Dan;
Wang, Wenbin;
Wu, Xinyue;
Li, Minyue;
Yan, Xuelong;
Hua, Zhonghong;
Liu, Jiahui;
Zhu, Zhiyu;
Hu, Kun;
Ren, Jie

Publication type:

Article

麝鼠 Bad 基因生物信息学分析.

Published in:

Chinese Journal of Wildlife / Yesheng Dongwu Xuebao, 2025, v. 46, n. 1, p. 81, doi. 10.12375/ysdwxb.20250109

By:

崔元曦;
田宇;
佟晓凤;
苏醒;
华思锐;
白素英

Publication type:

Article

Role of layilin in regulating mitochondria-mediated apoptosis: a study on B cell lymphoma (BCL)-2 family proteins.

Published in:

BMC Molecular & Cell Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12860-024-00521-9

By:

Arito, Mitsumi;
Tsutiya, Atsuhiro;
Sato, Masaaki;
Omoteyama, Kazuki;
Sato, Toshiyuki;
Motonaga, Yusei;
Suematsu, Naoya;
Kurokawa, Manae S.;
Kato, Tomohiro

Publication type:

Article

microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00455-0

By:

Wang, Jing;
Li, Guokai;
Lin, Min;
Lin, Sheng;
Wu, Ling

Publication type:

Article

Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00209-9

By:

White, Brian S.;
Khan, Suleiman A.;
Mason, Mike J.;
Ammad-ud-din, Muhammad;
Potdar, Swapnil;
Malani, Disha;
Kuusanmäki, Heikki;
Druker, Brian J.;
Heckman, Caroline;
Kallioniemi, Olli;
Kurtz, Stephen E.;
Porkka, Kimmo;
Tognon, Cristina E.;
Tyner, Jeffrey W.;
Aittokallio, Tero;
Wennerberg, Krister;
Guinney, Justin

Publication type:

Article

Effects of stem cell-derived exosomes on neuronal apoptosis and inflammatory cytokines in rats with cerebral ischemia-reperfusion injury via PI3K/AKT pathway-mediated mitochondrial apoptosis.

Published in:

Immunopharmacology & Immunotoxicology, 2021, v. 43, n. 6, p. 731, doi. 10.1080/08923973.2021.1976794

By:

Zhang, Ying;
Yu, Jun;
Liu, Jing;
Liu, Hongbiao;
Li, Jing

Publication type:

Article

虫草素对肺癌细胞生长及迁移的影响.

Published in:

Mycosystema, 2022, v. 41, n. 7, p. 1088, doi. 10.13346/j.mycosystema.210469

By:

宋羚;
田迪;
黄蓉;
刘新会;
罗家兴;
马啸

Publication type:

Article

Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01901-y

By:

Schmitt, Laura;
Lechtenberg, Ilka;
Drießen, Daniel;
Flores-Romero, Hector;
Skowron, Margaretha A.;
Sekeres, Marlena;
Hoppe, Julia;
Krings, Karina S.;
Llewellyn, Tanya R.;
Peter, Christoph;
Stork, Björn;
Qin, Nan;
Bhatia, Sanil;
Nettersheim, Daniel;
Fritz, Gerhard;
García-Sáez, Ana J.;
Müller, Thomas J. J.;
Wesselborg, Sebastian

Publication type:

Article

LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-023-01763-w

By:

Lindenboim, Liora;
Zohar, Hila;
Gundersen, Gregg G.;
Worman, Howard J.;
Stein, Reuven

Publication type:

Article

Retrospective analysis of primary gastric diffuse large B-cell lymphoma: a single center study from Turkey.

Published in:

Turkish Journal of Medical Sciences, 2017, v. 47, n. 1, p. 240, doi. 10.3906/sag-1510-40

By:

SOYER, Nur;
YILMAZ, Asu Fergün;
ÖZSAN, Nazan;
ŞAHİN, Fahri;
SAYDAM, Güray;
TOMBULOĞLU, Murat;
HEKİMGİL, Mine;
VURAL, Filiz

Publication type:

Article

Dysregulation of nitric oxide synthase activity and Bcl-2 and caspase-3 gene expressions in renal tissue of streptozotocin-induced diabetic rats.

Published in:

Turkish Journal of Medical Sciences, 2012, v. 42, n. 5, p. 830, doi. 10.3906/sag-1104-38

By:

Aktuğ, Hüseyin;
Çetintaş, Vildan Bozok;
Kosova, Buket;
Oltulu, Fatih;
Demiray, Şirin Bakti;
Çavuşoğlu, Türker;
Akarca, Saadet Özen;
Yavaşoğlu, Altuğ

Publication type:

Article

Hesperetin attenuates UVA‐induced photodamage in human dermal fibroblast cells.

Published in:

Journal of Cosmetic Dermatology, 2022, v. 21, n. 11, p. 6261, doi. 10.1111/jocd.15230

By:

Lu, Zhiyu;
Xia, Qingyue;
Cheng, Yuxin;
Lu, Qian;
Li, Yueyue;
Zeng, Ni;
Luan, Xingbao;
Li, Yuan;
Fan, Lipan;
Luo, Dan

Publication type:

Article

Astragaloside prevents UV‐induced keratinocyte injury by regulating TLR4/NF‐κB pathway.

Published in:

Journal of Cosmetic Dermatology, 2022, v. 21, n. 3, p. 1163, doi. 10.1111/jocd.14174

By:

Wang, Jie;
Ke, Jin;
Wu, Xing;
Yan, Yuehua

Publication type:

Article

Exploring the Potential of Plumbagin as an Activator of Caspase 3 for Non-small Cell Lung Carcinoma: A Comprehensive in silico Study.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2024, v. 58, n. 2, p. 526, doi. 10.5530/ijper.58.2.59

By:

Saeed, Mohd;
Tasleem, Munazzah;
Siddiqui, Samra;
Upadhyay, Tarun Kumar;
Bhardwaj, Tulika;
Alam, Md Jahoor;
Alqathani, Saad Saeed;
Bardakci, Fevzi;
Almuzaini, Nujud;
Hussain Abdalla, Rania Abdeen;
Shoaib, Ambreen

Publication type:

Article

SYNTHESIS OF RUTHENIUM COMPLEXES AND ASSESSING THEIR ANTICANCER AND ANTIBACTERIAL EFFECTS.

Published in:

Farmacia, 2023, v. 71, n. 6, p. 1129, doi. 10.31925/farmacia.2023.6.3

By:

ZEIZ, ALI;
CHAYYA, SUZANNE;
KASSEM, ZEINAB;
HIJAZI, AKRAM;
KHAWAJA, GHADA;
EL-DAKDOUKI, MOHAMMAD H.

Publication type:

Article

COMBINATION TREATMENT OF LITHOSPERMUM ERYTHRORHIZON POLYSACCHARIDE AND AUTOPHAGY INHIBITORS ON HEPATOMA CELLS INHIBITION AND THE UNDERLYING MECHANISM.

Published in:

Farmacia, 2022, v. 70, n. 3, p. 434, doi. 10.31925/farmacia.2022.3.8

By:

YINGJUN CHEN;
YUECUI LI;
YONGXI TONG;
JUNWEI WANG;
CHANDI XU;
SHANSHAN CHU;
LI YU;
JIANZHI BAO;
YEJIAO ZHANG

Publication type:

Article

THE PROTECTIVE EFFECT AND THE UNDERLYING MECHANISM OF EPHEDRA SINICA STAPF ON RENAL INJURY IN A MURINE MODEL.

Published in:

Farmacia, 2020, v. 68, n. 3, p. 476, doi. 10.31925/farmacia.2020.3.13

By:

XUE WANG;
WEI FU;
HAIYANG LIU;
ZHIBIN WANG;
HAIXUE KUANG;
QIUHONG WANG

Publication type:

Article

Turkish Propolis and Its Nano Form Can Ameliorate the Side Effects of Cisplatin, Which Is a Widely Used Drug in the Treatment of Cancer.

Published in:

Plants (2223-7747), 2020, v. 9, n. 9, p. 1075, doi. 10.3390/plants9091075

By:

Tatli Seven, Pinar;
Seven, Ismail;
Karakus, Selcan;
Iflazoglu Mutlu, Seda;
Arkali, Gozde;
Muge Sahin, Yesim;
Kilislioglu, Ayben

Publication type:

Article

BNIP3 in melanoma: isn't it IRONic?

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 4, p. 1, doi. 10.1080/23723556.2021.1947169

By:

Vara-Pérez, Mónica;
Agostinis, Patrizia

Publication type:

Article

Yes, MAM!

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 4, p. 1, doi. 10.1080/23723556.2021.1919473

By:

Means, Robert E.;
Katz, Samuel G.

Publication type:

Article

Repurposing ribosome-targeting antibiotics to overcome resistance to venetoclax in acute myeloid leukemia.

Published in:

2020

By:

Sharon, David;
Chan, Steven M.

Publication type:

Opinion

痹痿同治法对脂多糖诱导大鼠退变软骨细胞炎症和凋亡的影响.

Published in:

Journal of Beijing University of Traditional Chinese Medicine, 2022, n. 11, p. 1142, doi. 10.3969/j.issn.1006-2157.2022.11.008

By:

耿秋东;
牛素生;
张燕;
王和鸣;
李楠

Publication type:

Article

参白颗粒对胃癌前病变患者胃黏膜上皮细胞自噬与凋亡的调控作用.

Published in:

Journal of Beijing University of Traditional Chinese Medicine, 2022, n. 10, p. 1052, doi. 10.3969/j.issn.1006-2157.2022.10.013

By:

张忠绵;
黄佳钦;
贺柏翔;
林稼樱;
叶王宇;
曹云;
张希颜;
陈嘉钦;
李志红

Publication type:

Article

Fibrin-associated diffuse large B-cell lymphoma in a hemorrhagic cranial arachnoid cyst.

Published in:

2017

By:

Kirschenbaum, Daniel;
Prömmel, Peter;
Vasella, Flavio;
Haralambieva, Eugenia;
Marques Maggio, Ewerton;
Reisch, Robert;
Beer, Marc;
Camenisch, Ulrike;
Rushing, Elisabeth J.

Publication type:

Letter to the Editor

Baicalein alleviates palmitic acid-induced endothelial cell dysfunction via inhibiting endoplasmic reticulum stress.

Published in:

Clinical Hemorheology & Microcirculation, 2024, v. 88, n. 2, p. 235, doi. 10.3233/CH-242230

By:

Chen, Jian;
Chen, Fei-yu;
Lu, Chan-jun;
Yi, Sheng-wu

Publication type:

Article