Works matching DE "AUTOPHOSPHORYLATION"

Results: 281

Effect of pH on the cyanobacterial circadian oscillator in vitro.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08273-8

By:

Ito-Miwa, Kumiko;
Onoue, Yasuhiro;
Kondo, Takao;
Terauchi, Kazuki

Publication type:

Article

Subversive bacteria reveal new tricks in their cytoskeleton-hijacking arsenal.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 178, doi. 10.1038/nsmb.2976

By:

Dominguez, Roberto

Publication type:

Article

Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 10, p. 1182, doi. 10.1038/nsmb.2668

By:

De Nicola, Gian Felice;
Martin, Eva Denise;
Chaikuad, Apirat;
Bassi, Rekha;
Clark, James;
Martino, Luigi;
Verma, Sharwari;
Sicard, Pierre;
Tata, Renée;
Atkinson, R Andrew;
Knapp, Stefan;
Conte, Maria R;
Marber, Michael S

Publication type:

Article

Masitinib demonstrates anti-proliferative and pro-apoptotic activity in primary and metastatic feline injection-site sarcoma cells*.

Published in:

Veterinary & Comparative Oncology, 2012, v. 10, n. 2, p. 143, doi. 10.1111/j.1476-5829.2011.00291.x

By:

Lawrence, J.;
Saba, C.;
Gogal, R.;
Lamberth, O.;
Vandenplas, M. L.;
Hurley, D. J.;
Dubreuil, P.;
Hermine, O.;
Dobbin, K.;
Turek, M.

Publication type:

Article

Dimerization and autophosphorylation of the MST family of kinases are controlled by the same set of residues.

Published in:

Biochemical Journal, 2023, v. 480, n. 15, p. 1165, doi. 10.1042/BCJ20230067

By:

Weingartner, Kyler A.;
Tran, Thao;
Tripp, Katherine W.;
Kavran, Jennifer M.

Publication type:

Article

N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum.

Published in:

Biochemical Journal, 2022, v. 479, n. 3, p. 337, doi. 10.1042/BCJ20210829

By:

Pazicky, Samuel;
Alder, Arne;
Mertens, Haydyn;
Svergun, Dmitri;
Gilberger, Tim;
Löw, Christian

Publication type:

Article

Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB.

Published in:

Biochemical Journal, 2020, v. 477, n. 20, p. 4053, doi. 10.1042/BCJ20200695

By:

Artim, Stephen C.;
Kiyatkin, Anatoly;
Lemmon, Mark A.

Publication type:

Article

Derivation of stationary distributions of biochemical reaction networks via structure transformation.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02117-x

By:

Hong, Hyukpyo;
Kim, Jinsu;
Ali Al-Radhawi, M.;
Sontag, Eduardo D.;
Kim, Jae Kyoung

Publication type:

Article

5,8-Dimethoxy-2-Nonylamino-Naphthalene-1,4-Dione Inhibits Vascular Smooth Muscle Cell Proliferation by Blocking Autophosphorylation of PDGF-Receptor β.

Published in:

Korean Journal of Physiology & Pharmacology, 2013, v. 17, n. 3, p. 203, doi. 10.4196/kjpp.2013.17.3.203

By:

Yohan Kim;
Jung-Jin Lee;
Sang-Gil Lee;
Sang-Hyuk Jung;
Joo-Hui Han;
So Young Yang;
Eunju Yun;
Gyu-Yong Song;
Chang-Seon Myung

Publication type:

Article

Inhibitors targeting the autophosphorylation of serine/threonine kinase of Streptococcus suis show potent antimicrobial activity.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.990091

By:

Haotian Li;
Tingting Li;
Qiao Hu;
Zhiming Yao;
Lu Li;
Qi Huang;
Rui Zhou

Publication type:

Article

A novel role for Plk4 in regulating cell spreading and motility.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3441, doi. 10.1038/onc.2014.275

By:

Rosario, C O;
Kazazian, K;
Zih, F S W;
Brashavitskaya, O;
Haffani, Y;
Xu, R S Z;
George, A;
Dennis, J W;
Swallow, C J

Publication type:

Article

Severe progressive obstructive cardiomyopathy and renal tubular dysfunction in Donohue syndrome with decreased insulin receptor autophosphorylation due to a novel INSR mutation.

Published in:

European Journal of Pediatrics, 2013, v. 172, n. 8, p. 1125, doi. 10.1007/s00431-012-1901-7

By:

Hovnik, Tinka;
Bratanič, Nevenka;
Podkrajšek, Katarina;
Kovač, Jernej;
Paro, Darja;
Podnar, Tomaž;
Bratina, Nataša;
Battelino, Tadej

Publication type:

Article

A point mutation in the kinase domain of CRK10 leads to xylem vessel collapse and activation of defence responses in Arabidopsis.

Published in:

Journal of Experimental Botany, 2023, v. 74, n. 10, p. 3104, doi. 10.1093/jxb/erad080

By:

Piovesana, Maiara;
Wood, Ana K M;
Smith, Daniel P;
Deery, Michael J;
Bayliss, Richard;
Carrera, Esther;
Wellner, Nikolaus;
Kosik, Ondrej;
Napier, Johnathan A;
Kurup, Smita;
Matthes, Michaela C

Publication type:

Article

Low-fluence blue light-induced phosphorylation of Zmphot1 mediates the first positive phototropism.

Published in:

Journal of Experimental Botany, 2019, v. 70, n. 20, p. 5929, doi. 10.1093/jxb/erz344

By:

Suzuki, Hiromi;
Koshiba, Tomokazu;
Fujita, Chiharu;
Yamauchi, Yoshio;
Kimura, Taro;
Isobe, Toshiaki;
Sakai, Tatsuya;
Taoka, Masato;
Okamoto, Takashi

Publication type:

Article

Phosphorylation of the phytosulfokine peptide receptor PSKR1 controls receptor activity.

Published in:

Journal of Experimental Botany, 2017, v. 68, n. 7, p. 1411, doi. 10.1093/jxb/erx030

By:

Kaufmann, Christine;
Motzkus, Michael;
Sauter, Margret

Publication type:

Article

Autophosphorylation and Self-Activation of DNA-Dependent Protein Kinase.

Published in:

Genes, 2021, v. 12, n. 7, p. 1091, doi. 10.3390/genes12071091

By:

Kurosawa, Aya

Publication type:

Article

Anti-Tumor Effects of Gilteritinib on FLT3 Mutations: Insights into Resistance Mechanisms in Ba/F3 Cell Models.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 489, doi. 10.2147/OTT.S479519

By:

Nakazawa, Taisuke;
Tsuzuki, Hirofumi;
Kawase, Tatsuya;
Mori, Masamichi;
Yoshida, Taku

Publication type:

Article

4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity.

Published in:

Systems Biology in Reproductive Medicine, 2012, v. 58, n. 1, p. 57, doi. 10.3109/19396368.2011.648820

By:

Kappeler, Connie J.;
Hoyer, Patricia B.

Publication type:

Article

FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0200558

By:

Heim, Joel B.;
McDonald, Cera A.;
Wyles, Saranya P.;
Sominidi-Damodaran, Sindhuja;
Squirewell, Edwin J.;
Li, Ming;
Motsonelidze, Catherine;
Böttcher, Ralph T.;
van Deursen, Jan;
Meves, Alexander

Publication type:

Article

Autophosphorylation of Ser-6 via an intermolecular mechanism is important for the rapid reduction of NtCDPK1 kinase activity for substrate RSG.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0196357

By:

Ito, Takeshi;
Ishida, Sarahmi;
Takahashi, Yohsuke

Publication type:

Article

Parkinson disease related ATP13A2 evolved early in animal evolution.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0193228

By:

Sørensen, Danny Mollerup;
Holemans, Tine;
van Veen, Sarah;
Martin, Shaun;
Arslan, Tugce;
Haagendahl, Ida Winther;
Holen, Henrik Waldal;
Hamouda, Norin Nabil;
Eggermont, Jan;
Palmgren, Michael;
Vangheluwe, Peter

Publication type:

Article

LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00054

By:

Reynolds, April;
Doggett, Elizabeth A.;
Riddle, Steve M.;
Lebakken, Connie S.;
Nichols, R. Jeremy

Publication type:

Article

LRRK2 Kinase Activity and Biology are Not Uniformly Predicted by its Autophosphorylation and Cellular Phosphorylation Site Status.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00054

By:

Reynolds, April;
Doggett, Elizabeth A.;
Riddle, Steve M.;
Lebakken, Connie S.;
Nichols, R. Jeremy

Publication type:

Article

In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2.

Published in:

Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00051

By:

Vancraenenbroeck, Renée;
De Raeymaecker, Joren;
Lobbestael, Evy;
Gao, Fangye;
De Maeyer, Marc;
Voet, Arnout;
Baekelandt, Veerle;
Taymans, Jean-Marc

Publication type:

Article

CASK regulates CaMKII autophosphorylation in neuronal growth, calcium signaling, and learning.

Published in:

Frontiers in Molecular Neuroscience, 2013, v. 6, p. 1, doi. 10.3389/fnmol.2013.00027

By:

Gillespie, John M.;
Hodge, James J. L.

Publication type:

Article

Activation State-Dependent Substrate Gating in Ca2+/Calmodulin-Dependent Protein Kinase II.

Published in:

Neural Plasticity, 2017, p. 1, doi. 10.1155/2017/9601046

By:

Johnson, D. E.;
Hudmon, A.

Publication type:

Article

Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.

Published in:

Nature Medicine, 2013, v. 19, n. 11, p. 1469, doi. 10.1038/nm.3352

By:

Vaishnavi, Aria;
Capelletti, Marzia;
Le, Anh T;
Kako, Severine;
Butaney, Mohit;
Ercan, Dalia;
Mahale, Sakshi;
Davies, Kurtis D;
Aisner, Dara L;
Pilling, Amanda B;
Berge, Eamon M;
Kim, Jhingook;
Sasaki, Hidefumi;
Park, Seung-il;
Kryukov, Gregory;
Garraway, Levi A;
Hammerman, Peter S;
Haas, Julia;
Andrews, Steven W;
Lipson, Doron

Publication type:

Article

Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.

Published in:

Nature Genetics, 2012, v. 44, n. 2, p. 200, doi. 10.1038/ng.1027

By:

Rademakers, Rosa;
Baker, Matt;
Nicholson, Alexandra M;
Rutherford, Nicola J;
Finch, NiCole;
Soto-Ortolaza, Alexandra;
Lash, Jennifer;
Wider, Christian;
Wojtas, Aleksandra;
DeJesus-Hernandez, Mariely;
Adamson, Jennifer;
Kouri, Naomi;
Sundal, Christina;
Shuster, Elizabeth A;
Aasly, Jan;
MacKenzie, James;
Roeber, Sigrun;
Kretzschmar, Hans A;
Boeve, Bradley F;
Knopman, David S

Publication type:

Article

Interaction of Erdosteine with TrkA Signaling Pathways: Implications for Analgesia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4079, doi. 10.3390/ijms26094079

By:

Marchesi, Nicoletta;
Govoni, Stefano;
Page, Clive P.;
Diatchenko, Luda;
Pascale, Alessia;
Fantucci, Piercarlo;
Vertemara, Jacopo;
Natoli, Silvia;
Allegri, Massimo

Publication type:

Article

A Bioorganometallic Approach to Study Histidine Kinase Autophosphorylations.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 13, p. 3152, doi. 10.1002/chem.201605253

By:

Wang, Nan;
She, Zhe;
Ingar, Zakiyya;
Martic, Sanela;
Kraatz, Heinz‐Bernhard

Publication type:

Article

Evidence for aggregation of protein kinase CK2 in the cell: a novel strategy for studying CK2 holoenzyme interaction by BRET.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 397, n. 1/2, p. 285, doi. 10.1007/s11010-014-2196-y

By:

Hübner, Gerda;
Guerra, Barbara;
Issinger, Olaf-Georg;
Larsen, Jane;
Niefind, Karsten;
Vrecl, Milka

Publication type:

Article

Synthesis and evaluation of novel 18F‐labeled quinazoline derivatives with low lipophilicity for tumor PET imaging.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2018, v. 61, n. 2, p. 42, doi. 10.1002/jlcr.3538

By:

Chong, Yan;
Chang, Jin;
Zhao, Wenwen;
He, Yong;
Li, Yuqiao;
Zhang, Huabei;
Qi, Chuanmin

Publication type:

Article

Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.

Published in:

Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 9, p. 1613, doi. 10.1007/s00432-015-1924-3

By:

Golubovskaya, Vita;
O'Brien, Shalana;
Ho, Baotran;
Heffler, Melissa;
Conroy, Jeffrey;
Hu, Quang;
Wang, Dan;
Liu, Song;
Cance, William

Publication type:

Article

WalK(S221P), a naturally occurring mutation, confers vancomycin resistance in VISA strain XN108.

Published in:

2017

By:

Huagang Peng;
Qiwen Hu;
Weilong Shang;
Jizhen Yuan;
Xiaopeng Zhang;
Hui Liu;
Ying Zheng;
Zhen Hu;
Yi Yang;
Li Tan;
Shu Li;
Xiaomei Hu;
Ming Li;
Xiancai Rao;
Peng, Huagang;
Hu, Qiwen;
Shang, Weilong;
Yuan, Jizhen;
Zhang, Xiaopeng;
Liu, Hui

Publication type:

journal article

A high-throughput integrated microfluidics method enables tyrosine autophosphorylation discovery.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0286-9

By:

Nevenzal, Hadas;
Noach-Hirsh, Meirav;
Skornik-Bustan, Or;
Brio, Lev;
Barbiro-Michaely, Efrat;
Glick, Yair;
Avrahami, Dorit;
Lahmi, Roxane;
Tzur, Amit;
Gerber, Doron

Publication type:

Article

Sunitinib, a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Suppresses Neointimal Hyperplasia in Balloon-Injured Rat Carotid Artery.

Published in:

Journal of Cardiovascular Pharmacology & Therapeutics, 2013, v. 18, n. 4, p. 359, doi. 10.1177/1074248412472258

By:

Ishii, So;
Okamoto, Yoshihisa;
Katsumata, Harumi;
Egawa, Seiko;
Yamanaka, Daisuke;
Fukushima, Makoto;
Minami, Shiro

Publication type:

Article

pH sensing by FAK-His58 regulates focal adhesion remodeling.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 6, p. 849, doi. 10.1083/jcb.201302131

By:

Chang-Hoon Choi;
Webb, Bradley A.;
Chimenti, Michael S.;
Jacobson, Matthew P.;
Barber, Diane L.

Publication type:

Article

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.

Published in:

Journal of Cell Biology, 2012, v. 198, n. 2, p. 205, doi. 10.1083/jcb.201202152

By:

Yige Guo;
Kim, Christine;
Ahmad, Sana;
Zhang Jiayin;
Yinghui Mao

Publication type:

Article

Membrane extraction with styrene-maleic acid copolymer results in insulin receptor autophosphorylation in the absence of ligand.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07606-5

By:

Morrison, Kerrie A.;
Wood, Laura;
Edler, Karen J.;
Doutch, James;
Price, Gareth J.;
Koumanov, Francoise;
Whitley, Paul

Publication type:

Article

MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1672, doi. 10.3390/cells9071672

By:

Coelho, Nuno M.;
Wang, Andrew;
Petrovic, Petar;
Wang, Yongqiang;
Lee, Wilson;
McCulloch, Christopher A.

Publication type:

Article

Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1375, doi. 10.3390/cells9061375

By:

Duda, Przemysław;
Wójtowicz, Tomasz;
Janczara, Jakub;
Krowarsch, Daniel;
Czyrek, Aleksandra;
Gizak, Agnieszka;
Rakus, Dariusz

Publication type:

Article

Individual Differences in Ethanol Drinking and Seeking Behaviors in Rats Exposed to Chronic Intermittent Ethanol Vapor Exposure is Associated with Altered CaMKII Autophosphorylation in the Nucleus Accumbens Shell.

Published in:

Brain Sciences (2076-3425), 2019, v. 9, n. 12, p. 367, doi. 10.3390/brainsci9120367

By:

Somkuwar, Sucharita S.;
Mandyam, Chitra D.

Publication type:

Article

A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl) -3, 5, 7-triaza-1-azoniatricyclo [3.3.1.13,7]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, ...

Published in:

Carcinogenesis, 2012, v. 33, n. 5, p. 1004, doi. 10.1093/carcin/bgs120

By:

Golubovskaya, Vita M.;
Figel, Sheila;
Ho, Baotran T.;
Johnson, Christopher P.;
Yemma, Michael;
Huang, Grace;
Zheng, Min;
Nyberg, Carl;
Magis, Andrew;
Ostrov, David A.;
Gelman, Irwin H.;
Cance, William G.

Publication type:

Article

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29368-4

By:

Levina, Aleksandra;
Fleming, Kaelin D.;
Burke, John E.;
Leonard, Thomas A.

Publication type:

Article

The molecular basis of regulation of bacterial capsule assembly by Wzc.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24652-1

By:

Yang, Yun;
Liu, Jiwei;
Clarke, Bradley R.;
Seidel, Laura;
Bolla, Jani R.;
Ward, Philip N.;
Zhang, Peijun;
Robinson, Carol V.;
Whitfield, Chris;
Naismith, James H.

Publication type:

Article

The kinases HipA and HipA7 phosphorylate different substrate pools in Escherichia coli to promote multidrug tolerance.

Published in:

Science Signaling, 2018, v. 11, n. 547, p. 1, doi. 10.1126/scisignal.aat5750

By:

Semanjski, Maja;
Germain, Elsa;
Bratl, Katrin;
Kiessling, Andreas;
Gerdes, Kenn;
Macek, Boris

Publication type:

Article

Activation of master virulence regulator PhoP in acidic pH requires the Salmonella-specific protein UgtL.

Published in:

Science Signaling, 2017, v. 10, n. 494, p. 1

By:

Jeongjoon Choi;
Groisman, Eduardo A.

Publication type:

Article

Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases.

Published in:

Science Signaling, 2015, v. 8, n. 405, p. 1, doi. 10.1126/scisignal.aaa6711

By:

Qifang Xu;
Malecka, Kimberly L.;
Fink, Lauren;
Jordan, E. Joseph;
Duffy, Erin;
Kolander, Samuel;
Peterson, Jeffrey R.;
Dunbrack Jr., Roland L.

Publication type:

Article

Biophysical Characterization of Essential Phosphorylation at the Flexible C-Terminal Region of C-Raf with 14-3-3ζ Protein.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135976

By:

Ghosh, Anirban;
Ratha, Bhisma Narayan;
Gayen, Nilanjan;
Mroue, Kamal H.;
Kar, Rajiv K.;
Mandal, Atin K.;
Bhunia, Anirban

Publication type:

Article

Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128364

By:

Moccia, Marialuisa;
Liu, Qingsong;
Guida, Teresa;
Federico, Giorgia;
Brescia, Annalisa;
Zhao, Zheng;
Choi, Hwan Geun;
Deng, Xianming;
Tan, Li;
Wang, Jinhua;
Billaud, Marc;
Gray, Nathanael S.;
Carlomagno, Francesca;
Santoro, Massimo

Publication type:

Article