Works about AURORA kinases

Results: 570

Dawning aurora: TPXL3 activates α-Aurora kinase and regulates mitotic spindle morphogenesis.

Published in:

Plant Cell, 2025, v. 37, n. 4, p. 1, doi. 10.1093/plcell/koaf074

By:

Kolli, Renuka

Publication type:

Article

The unconventional TPX2 family protein TPXL3 regulates α Aurora kinase function in spindle morphogenesis in Arabidopsis.

Published in:

Plant Cell, 2025, v. 37, n. 4, p. 1, doi. 10.1093/plcell/koaf065

By:

Deng, Xingguang;
Higaki, Takumi;
Lin, Hong-Hui;
Lee, Yuh-Ru Julie;
Liu, Bo

Publication type:

Article

Parallel Chemical Genetic and Genome-Wide RNAi Screens Identify Cytokinesis Inhibitors and Targets.

Published in:

PLoS Biology, 2004, v. 2, n. 10, p. 1, doi. 10.1371/journal.pbio.0020379

By:

Eggert, Ulrike S;
Kiger, Amy A;
Richter, Constance;
Perlman, Zachary E;
Perrimon, Norbert;
Mitchison, Timothy J;
Field, Christine M

Publication type:

Article

The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2018, v. 137, n. 3, p. 481, doi. 10.1007/s11060-018-2755-2

By:

Zumbar, Cory T.;
Usubalieva, Aisulu;
King, Paul D.;
Li, Xiaohui;
Mifsud, Caroline S.;
Dalton, Hailey M.;
Sak, Muge;
Urio, Sara;
Bryant, William M.;
McElroy, Joseph P.;
Farmer, George;
Lehman, Norman L.

Publication type:

Article

Aurora kinase B/C inhibition impairs malignant glioma growth in vivo.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 3, p. 349, doi. 10.1007/s11060-012-0835-2

By:

Diaz, Roberto;
Golbourn, Brian;
Shekarforoush, Maryam;
Smith, Christian;
Rutka, James

Publication type:

Article

The promotion action of AURKA on post-ischemic angiogenesis in diabetes-related limb ischemia.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00635-4

By:

Bai, Tao;
Li, Mingxing;
Liu, Yuanfeng;
Qiao, Zhentao;
Zhang, Xusheng;
Wang, Yafeng;
Wang, Zhiwei

Publication type:

Article

Hsa_circRNA_007630 knockdown delays colon cancer progression by modulation of ferroptosis via miR‐506‐3p/AURKA axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 8, p. 1, doi. 10.1002/jbt.23771

By:

Hu, Ying;
Wu, Xiongjian;
Tan, Xiaobin;
Zhang, Jingzhi

Publication type:

Article

Contribution of Aurora-A and -B expression to DNA aneuploidy in gastric cancers.

Published in:

Surgery Today, 2014, v. 44, n. 3, p. 454, doi. 10.1007/s00595-013-0581-x

By:

Honma, Kenichi;
Nakanishi, Ryota;
Nakanoko, Tomonori;
Ando, Koji;
Saeki, Hiroshi;
Oki, Eiji;
Iimori, Makoto;
Kitao, Hiroyuki;
Kakeji, Yoshihiro;
Maehara, Yoshihiko

Publication type:

Article

In vitro evaluation of the Aurora kinase inhibitor VX-680 for Hepatoblastoma.

Published in:

Pediatric Surgery International, 2012, v. 28, n. 6, p. 579, doi. 10.1007/s00383-012-3086-6

By:

Dewerth, Alexander;
Wonner, Timo;
Lieber, Justus;
Ellerkamp, Verena;
Warmann, Steven;
Fuchs, Jörg;
Armeanu-Ebinger, Sorin

Publication type:

Article

The expression and prognosis for Aurora kinases in human non-small cell lung cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02878-5

By:

Wang, Yue;
Liu, Juan;
Xu, Jiaxue;
Ji, Zhaodong

Publication type:

Article

Synergistic effects of Aurora A and AKT inhibitors combined with radiation in colon cancer cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02562-8

By:

Peng, Qiuxia;
Zhou, Wei;
Li, Jie;
Liu, Danqing

Publication type:

Article

AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-024-01352-y

By:

Yang, Yang;
Li, Dan;
Liu, Zhigang;
Zhou, Kai;
Li, Wenxing;
Yang, Yanqi;
Sun, Ruifang;
Li, Yulong

Publication type:

Article

AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-024-01352-y

By:

Yang, Yang;
Li, Dan;
Liu, Zhigang;
Zhou, Kai;
Li, Wenxing;
Yang, Yanqi;
Sun, Ruifang;
Li, Yulong

Publication type:

Article

Design, synthesis, anticancer evaluation and docking studies of novel 2-(1-isonicotinoyl-3-phenyl-1H-pyrazol-4-yl)-3-phenylthiazolidin-4-one derivatives as Aurora-A kinase inhibitors.

Published in:

BMC Chemistry, 2022, v. 16, n. 1, p. 1, doi. 10.1186/s13065-022-00852-8

By:

Beniwal, Meenu;
Jain, Neelam;
Jain, Sandeep;
Aggarwal, Navidha

Publication type:

Article

Mutation of the SUMOylation site of Aurora-B disrupts spindle formation and chromosome alignment in oocytes.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02217-7

By:

Chen, Shan-Shan;
Li, Li;
Yao, Bo;
Guo, Jia-Lun;
Lu, Ping-Shuang;
Zhang, Hao-Lin;
Zhang, Kun-Huan;
Zou, Yuan-Jing;
Luo, Nan-Jian;
Sun, Shao-Chen;
Hu, Lin-Lin;
Ren, Yan-Ping

Publication type:

Article

Aurora Kinase A Regulation by Cysteine Oxidative Modification.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 531, doi. 10.3390/antiox12020531

By:

Lee, In-Gyun;
Lee, Bong-Jin

Publication type:

Article

Alisertib'in İyot-123 ile Radyoişaretlenme Potansiyelinin Araştırılması: Aurora A Kinaz İnhibitörünün Görüntülenme Potansiyelinin Değerlendirilmesi.

Published in:

Afyon Kocatepe University Journal of Science & Engineering / Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 2024, v. 24, n. 5, p. 1081, doi. 10.35414/akufemubid.1377776

By:

UYGUR, Emre;
SEZGİN, Ceren;
YILDIZ AKDAĞ, Berna;
ÖZBEY, Taylan;
PARLAK, Yasemin;
KARATAY, Kadriye Büşra;
GÜMÜŞER, Fikriye Gül;
MÜFTÜLER, Fazilet Zümrüt BİBER

Publication type:

Article

Dynamic localization of the chromosomal passenger complex in trypanosomes is controlled by the orphan kinesins KIN-A and KIN-B.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.93522

By:

Ballmer, Daniel;
Akiyoshi, Bungo

Publication type:

Article

The structural basis of the multi-step allosteric activation of Aurora B kinase.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85328

By:

Segura-Peña, Dario;
Hovet, Oda;
Gogoi, Hemanga;
Dawicki-McKenna, Jennine;
Wøien, Stine Malene Hansen;
Carrer, Manuel;
Black, Ben E.;
Cascella, Michele;
Sekulic, Nikolina

Publication type:

Article

Detection of Ligand‐induced Conformational Changes in the Activation Loop of Aurora‐A Kinase by PELDOR Spectroscopy.

Published in:

ChemistryOpen, 2016, v. 5, n. 6, p. 531, doi. 10.1002/open.201600101

By:

Burgess, Selena G.;
Bayliss, Richard;
Grazia Concilio, Maria;
Fielding, Alistair J.

Publication type:

Article

Multiplex Imaging and Cellular Target Identification of Kinase Inhibitors via an Affinity-Based Proteome Profiling Approach.

Published in:

Scientific Reports, 2015, p. 7724, doi. 10.1038/srep07724

By:

Pan, Sijun;
Wu, Xiaoyuan;
Li, Zhengqiu;
Yao, Shao Q.;
Hao, Piliang;
Sze, Siu Kwan;
Su, Ying;
Li, Lin

Publication type:

Article

Network Pharmacological Analysis Identifies the Curcumin Analog CCA-1.1 Targeting Mitosis Regulatory Process in HER2-Positive Breast Cancer.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2023, v. 34, n. 1, p. 54

By:

Novitasari, Dhania;
Jenie, Riris Istighfari;
Jun-ya Kato;
Edy Meiyanto

Publication type:

Article

Bioinformatic and Molecular Interaction Studies Uncover That CCA-1.1 and PGV-1 Differentially Target Mitotic Regulatory Protein and Have a Synergistic Effect against Leukemia Cells.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2022, v. 33, n. 2, p. 225

By:

Meiyanto, Edy;
Novitasari, Dhania;
Utomo, Rohmad Yudi;
Susidarti, Ratna Asmah;
Putri, Dyaningtyas Dewi Pamungkas;
Jun-ya Kato

Publication type:

Article

Editorial: The magic bullet evolution in tumor therapy: novel drug conjugates for targeted delivery.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1523948

By:

Gazzola, Silvia;
Neundorf, Ines;
Sewald, Norbert

Publication type:

Article

Identification of Hub Genes Associated With Immune Infiltration and Predict Prognosis in Hepatocellular Carcinoma via Bioinformatics Approaches.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.575762

By:

Chen, Huaping;
Wu, Junrong;
Lu, Liuyi;
Hu, Zuojian;
Li, Xi;
Huang, Li;
Zhang, Xiaolian;
Chen, Mingxing;
Qin, Xue;
Xie, Li

Publication type:

Article

A CPC-shelterin-BTR axis regulates mitotic telomere deprotection.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57456-8

By:

Romero-Zamora, Diana;
Rogers, Samuel;
Low, Ronnie Ren Jie;
Page, Scott G.;
Lane, Blake J. E.;
Kosaka, Shunya;
Robinson, Andrew B.;
French, Lucy;
Lamm, Noa;
Ishikawa, Fuyuki;
Hayashi, Makoto T.;
Cesare, Anthony J.

Publication type:

Article

High-throughput screening identifies Aurora kinase B as a critical therapeutic target for Merkel cell carcinoma.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56504-7

By:

Gelb, Tara;
Garman, Khalid A.;
Urban, Daniel;
Coxon, Amy;
Gryder, Berkley;
Hill, Natasha T.;
Miao, Lingling;
Lee, Tobie;
Lee, Olivia;
Chakka, Sirisha;
Braisted, John;
Jarvis, Jordan E.;
Glavin, Rachael;
Raj, Trisha S.;
Xiao, Ying;
Difilippantonio, Simone;
Wang, Amy Q.;
Shen, Min;
Cheng, Ken Chih-Chien;
Lal-Nag, Madhu

Publication type:

Article

Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50459-x

By:

Xu, Pengfei;
Yang, Joy C.;
Chen, Bo;
Ning, Shu;
Zhang, Xiong;
Wang, Leyi;
Nip, Christopher;
Shen, Yuqiu;
Johnson, Oleta T.;
Grigorean, Gabriela;
Phinney, Brett;
Liu, Liangren;
Wei, Qiang;
Corey, Eva;
Tepper, Clifford G.;
Chen, Hong-Wu;
Evans, Christopher P.;
Dall'Era, Marc A.;
Gao, Allen C.;
Gestwicki, Jason E.

Publication type:

Article

Identification of Aurora-A Inhibitors by Ligand and Structure-Based Virtual Screening.

Published in:

Molecular Informatics, 2014, v. 33, n. 5, p. 369, doi. 10.1002/minf.201300168

By:

Morshed, Mohammad Neaz

Publication type:

Article

VHL loss predicts response to Aurora kinase A inhibitor in renal cell carcinoma cells.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 1206, doi. 10.3892/mmr.2018.9038

By:

Ding, Xiao-Fei;
Zhou, Jun;
Chen, Guang;
Wu, Ying-Liang

Publication type:

Article

Alisertib induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 1, p. 394, doi. 10.3892/mmr.2016.5249

By:

YUNFENG FU;
YANAN ZHANG;
MENG GAO;
LINGLI QUAN;
RONG GUI;
JING LIU

Publication type:

Article

Let-7i inhibits the malignant phenotype of osteosarcoma cells by targeting Aurora-B.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3543, doi. 10.3892/mmr.2015.3798

By:

GUO MEI ZHANG;
XIN HUA LONG;
JIA MING LIU;
LIANG BO ZHU;
XUAN YIN CHEN;
SHAN HU HUANG;
ZHI HONG ZHANG;
ZHI LI LIU

Publication type:

Article

Amplifications of AURKA and AURKB in a Burkitt lymphoma immunodeficiencyassociated type: a case report.

Published in:

2023

By:

de Oliveira, Fábio Morato;
Gonçalves de Souza, Vinícius;
de Lourdes Carvalho, Aparecida;
Lizarte Neto, Fermino Sanches;
Siqueira Miranda, Carla Silva

Publication type:

Case Study

Comparative expression of soluble, active human kinases in specialized bacterial strains.

Published in:

PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0267226

By:

Sunderhaus, Allison;
Imran, Ramsha;
Enoh, Elanzou;
Adedeji, Adesola;
Obafemi, Taiye;
Abdel Aziz, May H.

Publication type:

Article

Aurora Kinase A Regulates M1 Macrophage Polarization and Plays a Role in Experimental Autoimmune Encephalomyelitis.

Published in:

Inflammation, 2015, v. 38, n. 2, p. 800, doi. 10.1007/s10753-014-9990-2

By:

Ding, Lixia;
Gu, Haijuan;
Gao, Xiaoming;
Xiong, Sidong;
Zheng, Biao

Publication type:

Article

O <sup>6</sup>-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo , and sensitivity to alisertib-carboplatin combination treatment.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1552015

By:

Sak, Müge;
Williams, Brian J.;
Hey, Andrew J.;
Sharma, Mayur;
Schier, Leslie;
Wilson, Megan J.;
Ortega, Mahatma;
Lara, Alyssa I.;
Brentlinger, Mikaela N.;
Lehman, Norman L.

Publication type:

Article

Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma.

Published in:

British Journal of Cancer, 2013, v. 109, n. 10, p. 2607, doi. 10.1038/bjc.2013.643

By:

Tavanti, E;
Sero, V;
Vella, S;
Fanelli, M;
Michelacci, F;
Landuzzi, L;
Magagnoli, G;
Versteeg, R;
Picci, P;
Hattinger, C M;
Serra, M

Publication type:

Article

Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis.

Published in:

British Journal of Cancer, 2013, v. 109, n. 9, p. 2445, doi. 10.1038/bjc.2013.608

By:

Goos, J A C M;
Coupe, V M H;
Diosdado, B;
Delis-Van Diemen, P M;
Karga, C;
Beliën, J A M;
Carvalho, B;
van den Tol, M P;
Verheul, H M W;
Geldof, A A;
Meijer, G A;
Hoekstra, O S;
Fijneman, R J A

Publication type:

Article

Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells.

Published in:

British Journal of Cancer, 2012, v. 107, n. 10, p. 1692, doi. 10.1038/bjc.2012.450

By:

Lin, Y;
Richards, F M;
Krippendorff, B-F;
Bramhall, J L;
Harrington, J A;
Bapiro, T E;
Robertson, A;
Zheleva, D;
Jodrell, D I

Publication type:

Article

Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer.

Published in:

British Journal of Cancer, 2012, v. 106, n. 11, p. 1798, doi. 10.1038/bjc.2012.167

By:

Ali, H R;
Dawson, S-J;
Blows, F M;
Provenzano, E;
Pharoah, P D;
Caldas, C

Publication type:

Article

Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer.

Published in:

British Journal of Cancer, 2012, v. 106, n. 4, p. 748, doi. 10.1038/bjc.2011.587

By:

Dotan, E;
Meropol, N J;
Zhu, F;
Zambito, F;
Bove, B;
Cai, K Q;
Godwin, A K;
Golemis, E A;
Astsaturov, I;
Cohen, S J

Publication type:

Article

The Role and Mechanisms of Aurora Kinases in Kidney Diseases.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 5, p. 1217, doi. 10.1002/cpt.3584

By:

Chang, Meiying;
Li, Qiuyi;
Shi, Zhenwei;
Zhuang, Shougang

Publication type:

Article

CELLULAR SENESCENCE CONTRIBUTES TO THE PROGRESSION OF HYPEROXIC BRONCHOPULMONARY DYSPLASIA.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 2, p. E1, doi. 10.1165/rcmb.2023-0038oc

By:

Xigang Jing;
Shuang Jia;
Teng, Maggie;
Day, Billy W.;
Afolayan, Adeleye J.;
Jarzembowski, Jason A.;
Chien-Wei Lin;
Hessner, Martin J.;
Pritchard Jr., Kirkwood A.;
Naylor, Stephen;
Konduri, G. Ganesh;
Ru-Jeng Teng

Publication type:

Article

Screening for Inhibitors of YAP Nuclear Localization Identifies Aurora Kinase A as a Modulator of Lung Fibrosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 67, n. 1, p. 36, doi. 10.1165/rcmb.2021-0428OC

By:

Yang Yang;
Santos, Daniela M.;
Pantano, Lorena;
Knipe, Rachel;
Abe, Elizabeth;
Logue, Amanda;
Pronzati, Gina;
Black, Katharine E.;
Spinney, Jillian J.;
Giacona, Francesca;
Bieler, Michael;
Godbout, Cedrickx;
Nicklin, Paul;
Wyatt, David;
Tager, Andrew M.;
Seither, Peter;
Herrmann, Franziska E.;
Medoff, Benjamin D.

Publication type:

Article

Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-024-13260-z

By:

Varshney, Nidhi;
Singh, Siddharth;
Kandpal, Meenakshi;
Saini, Vaishali;
Roberston, Erle S.;
Jha, Hem Chandra

Publication type:

Article

Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer.

Published in:

BMC Biology, 2017, v. 15, p. 1, doi. 10.1186/s12915-016-0335-5

By:

Jing Wang;
Nikhil, Kumar;
Viccaro, Keith;
Lei Chang;
White, Jacoba;
Shah, Kavita

Publication type:

Article

Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy.

Published in:

Molecular Cancer, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12943-020-01305-3

By:

Du, Ruijuan;
Huang, Chuntian;
Liu, Kangdong;
Li, Xiang;
Dong, Zigang

Publication type:

Article

TPX2 Protein of Arabidopsis Activates Aurora Kinase 1, But Not Aurora Kinase 3 In Vitro.

Published in:

Plant Molecular Biology Reporter, 2015, v. 33, n. 6, p. 1988, doi. 10.1007/s11105-015-0890-x

By:

Tomaštíková, Eva;
Demidov, Dmitri;
Jeřábková, Hana;
Binarová, Pavla;
Houben, Andreas;
Doležel, Jaroslav;
Petrovská, Beáta

Publication type:

Article

The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo.

Published in:

Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 2, p. 191, doi. 10.1007/s00280-023-04503-0

By:

Sak, Müge;
Williams, Brian J.;
Zumbar, Cory T.;
Teer, Landon;
Al-Kawaaz, Mustafa N. G.;
Kakar, Aastha;
Hey, Andrew J.;
Wilson, Megan J.;
Schier, Leslie M.;
Chen, Joseph;
Lehman, Norman L.

Publication type:

Article

Correction to: Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.

Published in:

2021

By:

Goto, Hiroaki;
Yoshino, Yuki;
Ito, Mieko;
Nagai, Junichi;
Kumamoto, Tadashi;
Inukai, Takesi;
Sakurai, Yukari;
Miyagawa, Naoyuki;
Keino, Dai;
Yokosuka, Tomoko;
Iwasaki, Fuminori;
Hamanoue, Satoshi;
Shiomi, Masae;
Goto, Shoko

Publication type:

corrected article