Works matching DE "ATAXIA telangiectasia mutated protein"

Results: 197

UBQLN4 promotes non-homologous end joining by repressing DNA end-resection.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 2, p. 1, doi. 10.1080/23723556.2019.1575692

By:

Jachimowicz, Ron D.;
Reinhardt, H. Christian

Publication type:

Article

Radiofluorination of a highly potent ATM inhibitor as a potential PET imaging agent.

Published in:

EJNMMI Research, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13550-022-00920-z

By:

Fraser, Claudia Rose;
Ajenjo, Javier;
Veal, Mathew;
Dias, Gemma Marie;
Chan, Chung;
O'Neill, Edward;
Destro, Gianluca;
Lau, Doreen;
Pacelli, Anna;
Gouverneur, Veronique;
Hueting, Rebekka;
Cornelissen, Bart

Publication type:

Article

Six Novel ATM Gene Variants in Sri Lankan Patients with Ataxia Telangiectasia.

Published in:

Case Reports in Genetics, 2020, p. 1, doi. 10.1155/2020/6630300

By:

Hettiarachchi, D.;
Panchal, Hetalkumar;
Pathirana, B. A. P. S.;
Rathnayaka, P. D.;
Padeniya, A.;
Lai, P. S.;
Dissanayake, V. H. W.

Publication type:

Article

Six Novel ATM Gene Variants in Sri Lankan Patients with Ataxia Telangiectasia.

Published in:

Case Reports in Genetics, 2020, p. 1, doi. 10.1155/2020/6630300

By:

Hettiarachchi, D.;
Panchal, Hetalkumar;
Pathirana, B. A. P. S.;
Rathnayaka, P. D.;
Padeniya, A.;
Lai, P. S.;
Dissanayake, V. H. W.

Publication type:

Article

Endonuclease G initiates DNA rearrangements at the MLL breakpoint cluster upon replication stress.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3391, doi. 10.1038/onc.2014.268

By:

Gole, B;
Baumann, C;
Mian, E;
Ireno, C I;
Wiesmüller, L

Publication type:

Article

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

Published in:

Oncogene, 2015, v. 34, n. 25, p. 3336, doi. 10.1038/onc.2014.266

By:

Thomas, A;
Perry, T;
Berhane, S;
Oldreive, C;
Zlatanou, A;
Williams, L R;
Weston, V J;
Stankovic, T;
Kearns, P;
Pors, K;
Grand, R J;
Stewart, G S

Publication type:

Article

BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation.

Published in:

Oncogene, 2015, v. 34, n. 23, p. 3063, doi. 10.1038/onc.2014.235

By:

Wei, F;
Ojo, D;
Lin, X;
Wong, N;
He, L;
Yan, J;
Xu, S;
Major, P;
Tang, D

Publication type:

Article

CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress.

Published in:

Oncogene, 2015, v. 34, n. 23, p. 2978, doi. 10.1038/onc.2014.248

By:

Sarmento, L M;
Póvoa, V;
Nascimento, R;
Real, G;
Antunes, I;
Martins, L R;
Moita, C;
Alves, P M;
Abecasis, M;
Moita, L F;
Parkhouse, R M E;
Meijerink, J P P;
Barata, J T

Publication type:

Article

TACC3 deregulates the DNA damage response and confers sensitivity to radiation and PARP inhibition.

Published in:

Oncogene, 2015, v. 34, n. 13, p. 1667, doi. 10.1038/onc.2014.105

By:

Ha, G-H;
Kim, J-L;
Petersson, A;
Oh, S;
Denning, M F;
Patel, T;
Breuer, E-K

Publication type:

Article

ATM-mediated phosphorylation of the chromatin remodeling enzyme BRG1 modulates DNA double-strand break repair.

Published in:

Oncogene, 2015, v. 34, n. 3, p. 303, doi. 10.1038/onc.2013.556

By:

Kwon, S-J;
Park, J-H;
Park, E-J;
Lee, S-A;
Lee, H-S;
Kang, S W;
Kwon, J

Publication type:

Article

The tumor suppressor, TAX1BP2, is a novel substrate of ATM kinase.

Published in:

Oncogene, 2014, v. 33, n. 45, p. 5303, doi. 10.1038/onc.2013.481

By:

Lai, W L;
Hung, W Y;
Ching, Y P

Publication type:

Article

ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells.

Published in:

Cellular Oncology (2211-3428), 2024, v. 47, n. 1, p. 245, doi. 10.1007/s13402-023-00866-x

By:

Deng, Tanggang;
Xie, Lin;
Xiaofang, Chen;
Zhang, Zhenbin;
Xiao, Yugang;
Peng, Yuchong;
Yin, Linglong;
Fu, Yongming;
Li, Xiong

Publication type:

Article

Multidisciplinary Management of Ataxia Telangiectasia: Current Perspectives.

Published in:

Journal of Multidisciplinary Healthcare, 2021, v. 14, p. 1637, doi. 10.2147/JMDH.S295486

By:

McGrath-Morrow, Sharon A;
Rothblum-Oviatt, Cynthia C;
Wright, Jennifer;
Schlechter, Haley;
Lefton-Greif, Maureen A;
Natale, Valerie A;
Crawford, Thomas O;
Lederman, Howard M

Publication type:

Article

Characterization of Glioma Stem Cells Through Multiple Stem Cell Markers and Their Specific Sensitization to Double-Strand Break-Inducing Agents by Pharmacological Inhibition of Ataxia Telangiectasia Mutated Protein.

Published in:

Brain Pathology, 2012, v. 22, n. 5, p. 677, doi. 10.1111/j.1750-3639.2012.00566.x

By:

Raso, Alessandro;
Vecchio, Donatella;
Cappelli, Enrico;
Ropolo, Monica;
Poggi, Alessandro;
Nozza, Paolo;
Biassoni, Roberto;
Mascelli, Samantha;
Capra, Valeria;
Kalfas, Fotios;
Severi, Paolo;
Frosina, Guido

Publication type:

Article

Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants.

Published in:

Journal of Pathology, 2022, v. 258, n. 1, p. 83, doi. 10.1002/path.5979

By:

Bueno‐Martínez, Elena;
Sanoguera‐Miralles, Lara;
Valenzuela‐Palomo, Alberto;
Esteban‐Sánchez, Ada;
Lorca, Víctor;
Llinares‐Burguet, Inés;
Allen, Jamie;
García‐Álvarez, Alicia;
Pérez‐Segura, Pedro;
Durán, Mercedes;
Easton, Douglas F;
Devilee, Peter;
Vreeswijk, Maaike PG;
de la Hoya, Miguel;
Velasco‐Sampedro, Eladio A

Publication type:

Article

Influence of Individual Radiosensitivity on the Hormesis Phenomenon: Toward a Mechanistic Explanation Based on the Nucleoshuttling of ATM Protein.

Published in:

Dose-Response, 2020, v. 18, n. 2, p. 1, doi. 10.1177/1559325820913784

By:

Devic, Clément;
Ferlazzo, Mélanie L.;
Berthel, Elise;
Foray, Nicolas

Publication type:

Article

Radiofrequency ablation triggers the migration of hepatocellular carcinoma cells by suppressing miR-148a-5p.

Published in:

Biological Chemistry, 2020, v. 401, n. 8, p. 985, doi. 10.1515/hsz-2020-0130

By:

Wang, Haicun;
Cao, Yang;
Hu, Kaiwen;
Li, Quanwang;
Yang, Yufei;
Wang, Lanrong;
Qin, Xiaoyan;
Qiao, Bingli;
Cheng, Liuqi;
Li, Peipei;
Dui, Weihua

Publication type:

Article

Relationship between ATM and Ribosomal Protein S6 Revealed by the Chemical Inhibition of Ser/Thr Protein Phosphatase Type 1.

Published in:

Bioscience, Biotechnology & Biochemistry, 2012, v. 76, n. 3, p. 486, doi. 10.1271/bbb.110774

By:

Ying Li;
Mitsuhashi, Shinya;
Ikejo, Makoto;
Miura, Nobuaki;
Kawamura, Takeshi;
Hamakubo, Takao;
Ubukata, Makoto

Publication type:

Article

ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.

Published in:

Journal of Neuro-Oncology, 2012, v. 110, n. 3, p. 349, doi. 10.1007/s11060-012-0979-0

By:

Nadkarni, Aditi;
Shrivastav, Meena;
Mladek, Ann;
Schwingler, Paul;
Grogan, Patrick;
Chen, Junjie;
Sarkaria, Jann

Publication type:

Article

ATM Protein Kinase Signaling, Type 2 Diabetes and Cardiovascular Disease.

Published in:

Cardiovascular Drugs & Therapy, 2015, v. 29, n. 1, p. 51, doi. 10.1007/s10557-015-6571-z

By:

Espach, Yolandi;
Lochner, Amanda;
Strijdom, Hans;
Huisamen, Barbara

Publication type:

Article

Development of Serous Ovarian Cancer is Associated with the Expression of Homologous Recombination Pathway Proteins.

Published in:

Pathology & Oncology Research, 2014, v. 20, n. 2, p. 1, doi. 10.1007/s12253-014-9776-8

By:

Qingqing Ye;
Li Chen;
Xiaolu Yin;
Liu, Yuan Jie Charles;
Qunsheng Ji;
Enfeng Zhao

Publication type:

Article

MicroRNA-181a Functions as an Oncomir in Gastric Cancer by Targeting the Tumour Suppressor Gene ATM.

Published in:

Pathology & Oncology Research, 2014, v. 20, n. 2, p. 381, doi. 10.1007/s12253-013-9707-0

By:

Zhang, Xiangyang;
Nie, Yuqiang;
Li, Xiaorong;
Wu, Guifu;
Huang, Qun;
Cao, Jie;
Du, Yanlei;
Li, Junda;
Deng, Ruoyu;
Huang, Dongshen;
Chen, Baozhi;
Li, Shang;
Wei, Baojun

Publication type:

Article

NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 1, p. 157, doi. 10.1007/s00401-019-02086-w

By:

Yu, Yanan;
Choi, Kwangmin;
Wu, Jianqiang;
Andreassen, Paul R.;
Dexheimer, Phillip J.;
Keddache, Mehdi;
Brems, Hilde;
Spinner, Robert J.;
Cancelas, Jose A.;
Martin, Lisa J.;
Wallace, Margaret R.;
Legius, Eric;
Vogel, Kristine S.;
Ratner, Nancy

Publication type:

Article

ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution.

Published in:

Blood Cancer Journal, 2022, v. 12, n. 6, p. 1, doi. 10.1038/s41408-022-00686-6

By:

Royo, Romina;
Magnano, Laura;
Delgado, Julio;
Ruiz-Gil, Sara;
Gelpí, Josep Ll.;
Heyn, Holger;
Taylor, Malcom A.;
Stankovic, Tatjana;
Puente, Xose S.;
Nadeu, Ferran;
Campo, Elías

Publication type:

Article

ATM functions at the peroxisome to induce pexophagy in response to ROS.

Published in:

Nature Cell Biology, 2015, v. 17, n. 10, p. 1259, doi. 10.1038/ncb3230

By:

Kastan, Michael B.;
Zhang, Jiangwei;
Tripathi, Durga Nand;
Jing, Ji;
Powell, Reid T.;
Dere, Ruhee;
Walker, Cheryl Lyn;
Alexander, Angela;
Kim, Jinhee;
Tait-Mulder, Jacqueline;
Lee, Ji-Hoon;
Paull, Tanya T.;
Pandita, Raj K.;
Charaka, Vijaya K.;
Pandita, Tej K.

Publication type:

Article

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

Published in:

Nature Cell Biology, 2014, v. 16, n. 9, p. 864, doi. 10.1038/ncb3013

By:

Zhang, Peijing;
Wei, Yongkun;
Wang, Li;
Debeb, Bisrat G.;
Yuan, Yuan;
Zhang, Jinsong;
Yuan, Jingsong;
Wang, Min;
Chen, Dahu;
Sun, Yutong;
Woodward, Wendy A.;
Liu, Yongqing;
Dean, Douglas C.;
Liang, Han;
Hu, Ye;
Ang, K. Kian;
Hung, Mien-Chie;
Chen, Junjie;
Ma, Li

Publication type:

Article

The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells.

Published in:

Nature Cell Biology, 2012, v. 14, n. 5, p. 535, doi. 10.1038/ncb2468

By:

Maryanovich, Maria;
Oberkovitz, Galia;
Niv, Hagit;
Vorobiyov, Lidiya;
Zaltsman, Yehudit;
Brenner, Ori;
Lapidot, Tsvee;
Jung, Steffen;
Gross, Atan

Publication type:

Article

ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?

Published in:

Carcinogenesis, 2017, v. 38, n. 12, p. 1196, doi. 10.1093/carcin/bgx100

By:

Huiyuan Zheng;
Högberg, Johan;
Stenius, Ulla

Publication type:

Article

Initiation of the ATM-Chk2 DNA damage response through the base excision repair.

Published in:

Carcinogenesis, 2015, v. 36, n. 8, p. 832, doi. 10.1093/carcin/bgv079

By:

Wen-Cheng Chou;
Ling-Yueh Hu;
Chia-Ni Hsiung;
Chen-Yang Shen

Publication type:

Article

Speckle-type POZ protein, SPOP, is involved in the DNA damage response.

Published in:

Carcinogenesis, 2014, v. 35, n. 8, p. 1691, doi. 10.1093/carcin/bgu022

By:

Zhang, Dan;
Wang, Haibo;
Sun, Mianen;
Yang, Jun;
Zhang, Wei;
Han, Suxia;
Xu, Bo

Publication type:

Article

Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copynumber driven cancers.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03730-x

By:

McGrail, Daniel J.;
Federico, Lorenzo;
Yongsheng Li;
Hui Dai;
Yiling Lu;
Mills, Gordon B.;
Song Yi;
Shiaw-Yih Lin;
Sahni, Nidhi

Publication type:

Article

The p53 pathway induction is not primarily dependent on Ataxia Telangiectasia Mutated (ATM) gene activity after fludarabine treatment in chronic lymphocytic leukemia cells.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 8, p. 1840, doi. 10.3109/10428194.2013.796056

By:

Navrkalova, Veronika;
Sebejova, Ludmila;
Zemanova, Jana;
Jaskova, Zuzana;
Trbusek, Martin

Publication type:

Article

Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 8, p. 1849, doi. 10.3109/10428194.2013.796058

By:

te Raa, G. Doreen;
Malcikova, Jitka;
Pospisilova, Sarka;
Trbusek, Martin;
Mraz, Mark;
Garff-Tavernier, Maria Le;
Merle-Béral, Hélène;
Lin, Ke;
Pettitt, Andrew R.;
Merkel, Olaf;
Stankovic, Tatjana;
van Oers, Marinus H.;
Eldering, Eric;
Stilgenbauer, Stephan;
Zenz, Thorsten;
Kater, Arnon P.

Publication type:

Article

First radiobiological characterization of the McCune–Albright syndrome: influence of the ATM protein and effect of statins + bisphosphonates treatment.

Published in:

International Journal of Radiation Biology, 2021, v. 97, n. 3, p. 317, doi. 10.1080/09553002.2021.1864045

By:

Bachelet, Jean-Thomas;
Granzotto, Adeline;
Ferlazzo, Mélanie;
Sonzogni, Laurène;
Berthel, Elise;
Devic, Clément;
Foray, Nicolas

Publication type:

Article

ATM, radiation, and the risk of second primary breast cancer.

Published in:

International Journal of Radiation Biology, 2017, v. 93, n. 10, p. 1121, doi. 10.1080/09553002.2017.1344363

By:

Bernstein, Jonine L.;
Concannon, Patrick

Publication type:

Article

The effect of ATM kinase inhibition on the initial response of human dental pulp and periodontal ligament mesenchymal stem cells to ionizing radiation.

Published in:

International Journal of Radiation Biology, 2013, v. 89, n. 7, p. 501, doi. 10.3109/09553002.2013.775530

By:

Cmielova, Jana;
Havelek, Radim;
Kohlerova, Renata;
Soukup, Tomas;
Bruckova, Lenka;
Suchanek, Jakub;
Vavrova, Jirina;
Mokry, Jaroslav;
Rezacova, Martina

Publication type:

Article

Breast cancer risks associated with missense variants in breast cancer susceptibility genes.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01052-8

By:

Dorling, Leila;
Carvalho, Sara;
Allen, Jamie;
Parsons, Michael T.;
Fortuno, Cristina;
González-Neira, Anna;
Heijl, Stephan M.;
Adank, Muriel A.;
Ahearn, Thomas U.;
Andrulis, Irene L.;
Auvinen, Päivi;
Becher, Heiko;
Beckmann, Matthias W.;
Behrens, Sabine;
Bermisheva, Marina;
Bogdanova, Natalia V.;
Bojesen, Stig E.;
Bolla, Manjeet K.;
Bremer, Michael;
Briceno, Ignacio

Publication type:

Article

ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2013, v. 32, n. 1, p. 1, doi. 10.1186/1756-9966-32-95

By:

Gilardini Montani, Maria Saveria;
Prodosmo, Andrea;
Stagni, Venturina;
Merli, Dania;
Monteonofrio, Laura;
Gatti, Veronica;
Gentileschi, Maria Pia;
Barilà, Daniela;
Soddu, Silvia

Publication type:

Article

A novel mathematical model of ATM/p53/NF-κB pathways points to the importance of the DDR switch-off mechanisms.

Published in:

BMC Systems Biology, 2016, v. 10, p. 1, doi. 10.1186/s12918-016-0293-0

By:

Jonak, Katarzyna;
Kurpas, Monika;
Szoltysek, Katarzyna;
Janus, Patryk;
Abramowicz, Agata;
Puszynski, Krzysztof

Publication type:

Article

ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels.

Published in:

British Journal of Cancer, 2015, v. 112, n. 6, p. 1059, doi. 10.1038/bjc.2015.60

By:

Rondeau, S;
Vacher, S;
De Koning, L;
Briaux, A;
Schnitzler, A;
Chemlali, W;
Callens, C;
Lidereau, R;
Bièche, I

Publication type:

Article

The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold.

Published in:

BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-114

By:

Loewer, Alexander;
Karanam, Ketki;
Mock, Caroline;
Lahav, Galit

Publication type:

Article

cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells.

Published in:

Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-36

By:

Eun-Ah Cho;
Eui-Jun Kim;
Sahng-June Kwak;
Yong-Sung Juhnn

Publication type:

Article

Prognostic relevance of ATM protein in uveal melanoma and its association with clinicopathological factors.

Published in:

International Journal of Clinical Oncology, 2019, v. 24, n. 12, p. 1526, doi. 10.1007/s10147-019-01519-6

By:

Jha, Jayanti;
Singh, Mithalesh Kumar;
Singh, Lata;
Pushker, Neelam;
Bajaj, Mandeep Singh;
Sen, Seema;
Kashyap, Seema

Publication type:

Article

MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer.

Published in:

Cancer Immunology, Immunotherapy, 2016, v. 65, n. 5, p. 499, doi. 10.1007/s00262-016-1814-9

By:

Okita, Riki;
Yukawa, Takuro;
Nojima, Yuji;
Maeda, Ai;
Saisho, Shinsuke;
Shimizu, Katsuhiko;
Nakata, Masao

Publication type:

Article

DNA damage response: The spliceosome cashes in at the ATM.

Published in:

Nature Reviews Molecular Cell Biology, 2015, v. 16, n. 8, p. 454, doi. 10.1038/nrm4026

By:

Zlotorynski, Eytan

Publication type:

Article

Peroxisomes take shape.

Published in:

Nature Reviews Molecular Cell Biology, 2013, v. 14, n. 12, p. 803, doi. 10.1038/nrm3700

By:

Smith, Jennifer J.;
Aitchison, John D.

Publication type:

Article

DNA repair: Repair with a twist.

Published in:

Nature Reviews Molecular Cell Biology, 2013, v. 14, n. 5, p. 268, doi. 10.1038/nrm3564

By:

David, Rachel

Publication type:

Article

33886 Deregulation of the LANCL2 Pathway in Alzheimer's Disease.

Published in:

2021

By:

Birnbaumria, Emily;
Figueiredo-Pereira, Maria;
Rockwell, Patrica;
Henchcliffe, Claire;
Serrano, Peter

Publication type:

Abstract

32219 Differences in cell death in methionine versus cysteine depletion.

Published in:

2021

By:

Wallis, Katherine F.;
Miousse, Isabelle R.

Publication type:

Abstract

Overexpression of Protein Kinase Mζ in the Prelimbic Cortex Enhances the Formation of Long-Term Fear Memory.

Published in:

Neuropsychopharmacology, 2015, v. 40, n. 9, p. 2146, doi. 10.1038/npp.2015.56

By:

Xue, Yan-Xue;
Zhu, Zhen-Zhen;
Han, Hai-Bin;
Liu, Jian-Feng;
Meng, Shi-Qiu;
Chen, Chen;
Yang, Jian-Li;
Wu, Ping;
Lu, Lin

Publication type:

Article