Works matching DE "ATAXIA telangiectasia mutated protein"

Results: 201

The influence of homologous recombination repair on temozolomide chemosensitivity in gliomas.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf017

By:

Zeng, Biyun;
Shi, Hansen;
Liu, Tiancai;
Tang, Jinjing;
Lin, Juncheng;
Lin, Xiaocong;
Zeng, Tao

Publication type:

Article

TTK activates ATR through RPA2 phosphorylation to promote olaparib resistance in ovarian cancer.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08444-7

By:

Qi, Gonghua;
Ma, Hanlin;
Chen, Jingying;
Gai, Panpan;
Teng, Kai

Publication type:

Article

MYO1B promotes radioresistance in head and neck squamous cell carcinoma by regulating tumor stemness and DNA damage repair via the PI3K/AKT pathway.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03863-2

By:

Li, Yanan;
Liu, Jiahao;
Wang, Zhen;
Zhang, Yilei;
Liu, Baiying;
Chu, Ling

Publication type:

Article

ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.

Published in:

Journal of Neuro-Oncology, 2012, v. 110, n. 3, p. 349, doi. 10.1007/s11060-012-0979-0

By:

Nadkarni, Aditi;
Shrivastav, Meena;
Mladek, Ann;
Schwingler, Paul;
Grogan, Patrick;
Chen, Junjie;
Sarkaria, Jann

Publication type:

Article

STEEx, a boundary between the world of quiescence and the vegetative cycle.

Published in:

Current Genetics, 2018, v. 64, n. 4, p. 901, doi. 10.1007/s00294-018-0808-x

By:

Maestroni, Laetitia;
Géli, Vincent;
Coulon, Stéphane

Publication type:

Article

Role of DNA damage in the progress of chronic tubule-interstitial injury.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 2, p. 1081, doi. 10.3892/mmr.2020.11146

By:

Sun, Linxiao;
Zhu, Xiandong;
Luo, Jiao;
Wang, Cheng;
Chen, Bicheng

Publication type:

Article

ATM mediates DAB2IP-deficient bladder cancer cell resistance to ionizing radiation through the p38MAPK and NF-κB signaling pathway.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 2, p. 1216, doi. 10.3892/mmr.2017.6689

By:

HUI HE;
RULVE CHANG;
TINGTING ZHANG;
CHEN YANG;
ZHAOLU KONG

Publication type:

Article

The Promotion of Genomic Instability in Human Fibroblasts by Adenovirus 12 Early Region 1B 55K Protein in the Absence of Viral Infection.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 12, p. 2444, doi. 10.3390/v13122444

By:

Abualfaraj, Tareq;
Hagkarim, Nafiseh Chalabi;
Hollingworth, Robert;
Grange, Laura;
Jhujh, Satpal;
Stewart, Grant S.;
Grand, Roger J.

Publication type:

Article

How Human Papillomavirus Replication and Immune Evasion Strategies Take Advantage of the Host DNA Damage Repair Machinery.

Published in:

Viruses (1999-4915), 2017, v. 9, n. 12, p. 390, doi. 10.3390/v9120390

By:

Bordignon, Valentina;
Di Domenico, Enea Gino;
Trento, Elisabetta;
D'agosto, Giovanna;
Cavallo, Ilaria;
Pontone, Martina;
Pimpinelli, Fulvia;
Mariani, Luciano;
Ensoli, Fabrizio

Publication type:

Article

Clinical Characterization and Mutation Analysis of 13 Iranian Ataxia Telangiectasia Patients: Introducing Two Novel Mutations.

Published in:

Iranian Journal of Allergy, Asthma & Immunology, 2025, v. 24, n. 2, p. 187, doi. 10.18502/ijaai.v24i2.18147

By:

Badalzadeh, Mohsen;
Bavani, Maryam Soleimani;
Alizadeh, Zahra;
Mirmoghtadaei, Milad;
Shakerian, Leila;
Bahram, Seiamak;
Molitor, Anne;
Carapito, Raphael;
Moradi, Leila;
Razaghian, Anahita;
Assari, Raheleh;
Movahedi, Masoud;
Shariat, Mansoureh;
Houshmand, Massoud;
Habibi, Laleh;
Hamidieh, Amir Ali;
Fazlollahi, Mahmoud;
Pourpak, Zahra

Publication type:

Article

A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma.

Published in:

Pigment Cell & Melanoma Research, 2016, v. 29, n. 3, p. 329, doi. 10.1111/pcmr.12466

By:

Spoerri, Loredana;
Brooks, Kelly;
Chia, KeeMing;
Grossman, Gavriel;
Ellis, Jonathan J.;
Dahmer ‐ Heath, Mareike;
Škalamera, Dubravka;
Pavey, Sandra;
Burmeister, Bryan;
Gabrielli, Brian

Publication type:

Article

Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 4, p. 601, doi. 10.1111/pcmr.12252

By:

Swope, Viki;
Alexander, Christina;
Starner, Renny;
Schwemberger, Sandy;
Babcock, George;
Abdel ‐ Malek, Zalfa A.

Publication type:

Article

ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels.

Published in:

British Journal of Cancer, 2015, v. 112, n. 6, p. 1059, doi. 10.1038/bjc.2015.60

By:

Rondeau, S;
Vacher, S;
De Koning, L;
Briaux, A;
Schnitzler, A;
Chemlali, W;
Callens, C;
Lidereau, R;
Bièche, I

Publication type:

Article

The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold.

Published in:

BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-114

By:

Loewer, Alexander;
Karanam, Ketki;
Mock, Caroline;
Lahav, Galit

Publication type:

Article

Post-Integrational DNA Repair of HIV-1 Is Associated with Activation of the DNA-PK and ATM Cellular Protein Kinases and Phosphorylation of Their Targets.

Published in:

Biochemistry (00062979), 2024, v. 89, n. 6, p. 1122, doi. 10.1134/S0006297924060117

By:

Anisenko, Andrey N.;
Nefedova, Anastasiia A.;
Kireev, Igor I.;
Gottikh, Marina B.

Publication type:

Article

Imatinib inhibits inactivation of the ATM/ATR signaling pathway and recovery from adriamycin/doxorubicin-induced DNA damage checkpoint arrest.

Published in:

Cell Biology International, 2015, v. 39, n. 8, p. 923, doi. 10.1002/cbin.10460

By:

Morii, Mariko;
Fukumoto, Yasunori;
Kubota, Sho;
Yamaguchi, Noritaka;
Nakayama, Yuji;
Yamaguchi, Naoto

Publication type:

Article

Role of ataxia-telangiectasia mutated (ATM) in porcine oocyte in vitro maturation.

Published in:

Cell Biology International, 2015, v. 39, n. 6, p. 710, doi. 10.1002/cbin.10439

By:

Lin, Zi‐Li;
Kim, Nam‐Hyung

Publication type:

Article

Myoclonus dystonia as a predominant manifestation in ataxia telangiectasia.

Published in:

2025

By:

Carvalho, Mitosha;
Mehta, Sahil;
Singh, Jagdeep;
Lal, Vivek

Publication type:

Letter

Radioresistance of chordoma cells is associated with the ATM/ATR pathway, in which RAD51 serves as an important downstream effector.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 3, p. 2171, doi. 10.3892/etm.2017.4736

By:

CHAO ZHANG;
BING WANG;
LEI LI;
YAWEI LI;
PENGZHI LI;
GUOHUA LV

Publication type:

Article

Radiosensitizing effects of miR‐18a‐5p on lung cancer stem‐like cells via downregulating both ATM and HIF‐1α.

Published in:

Cancer Medicine, 2018, v. 7, n. 8, p. 3834, doi. 10.1002/cam4.1527

By:

Chen, Xu;
Li, Dezhi;
Zhang, Luping;
Niu, Kai;
Kong, Rui;
Gu, Jiaoyang;
Xu, Zihan;
Chen, Zhengtang;
Sun, Jianguo;
Wu, Lei;
Xu, Yanmei

Publication type:

Article

ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution.

Published in:

Blood Cancer Journal, 2022, v. 12, n. 6, p. 1, doi. 10.1038/s41408-022-00686-6

By:

Royo, Romina;
Magnano, Laura;
Delgado, Julio;
Ruiz-Gil, Sara;
Gelpí, Josep Ll.;
Heyn, Holger;
Taylor, Malcom A.;
Stankovic, Tatjana;
Puente, Xose S.;
Nadeu, Ferran;
Campo, Elías

Publication type:

Article

Accelerated Aging Effects Observed In Vitro after an Exposure to Gamma-Rays Delivered at Very Low and Continuous Dose-Rate Equivalent to 1–5 Weeks in International Space Station.

Published in:

Cells (2073-4409), 2024, v. 13, n. 20, p. 1703, doi. 10.3390/cells13201703

By:

Restier-Verlet, Juliette;
Ferlazzo, Mélanie L.;
Granzotto, Adeline;
Al-Choboq, Joëlle;
Bellemou, Camélia;
Estavoyer, Maxime;
Lecomte, Florentin;
Bourguignon, Michel;
Pujo-Menjouet, Laurent;
Foray, Nicolas

Publication type:

Article

The Radiobiological Characterization of Human and Porcine Lens Cells Suggests the Importance of the ATM Kinase in Radiation-Induced Cataractogenesis.

Published in:

Cells (2073-4409), 2023, v. 12, n. 16, p. 2118, doi. 10.3390/cells12162118

By:

Al-Choboq, Joëlle;
Mathis, Thibaud;
Restier-Verlet, Juliette;
Sonzogni, Laurène;
El Nachef, Laura;
Granzotto, Adeline;
Bourguignon, Michel;
Foray, Nicolas

Publication type:

Article

Toward an Early Diagnosis for Alzheimer's Disease Based on the Perinuclear Localization of the ATM Protein.

Published in:

Cells (2073-4409), 2023, v. 12, n. 13, p. 1747, doi. 10.3390/cells12131747

By:

Berthel, Elise;
Pujo-Menjouet, Laurent;
Le Reun, Eymeric;
Sonzogni, Laurène;
Al-Choboq, Joëlle;
Chekroun, Abdennasser;
Granzotto, Adeline;
Devic, Clément;
Ferlazzo, Mélanie L.;
Pereira, Sandrine;
Bourguignon, Michel;
Foray, Nicolas

Publication type:

Article

FLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 889, doi. 10.3390/cells10040889

By:

Almozyan, Sheema;
Coulton, James;
Babaei-Jadidi, Roya;
Nateri, Abdolrahman S.;
Jetten, Anton M.

Publication type:

Article

ATM Protein Kinase: Old and New Implications in Neuronal Pathways and Brain Circuitry.

Published in:

Cells (2073-4409), 2020, v. 9, n. 9, p. 1969, doi. 10.3390/cells9091969

By:

Pizzamiglio, Lara;
Focchi, Elisa;
Antonucci, Flavia

Publication type:

Article

No evidence for DNA methylation of the ATM promoter CpG island in chronic lymphocytic leukemia.

Published in:

Leukemia & Lymphoma, 2012, v. 53, n. 7, p. 1420, doi. 10.3109/10428194.2011.653640

By:

Mikeska, Thomas;
Carney, Dennis A.;
Seymour, John F.;
Dobrovic, Alexander

Publication type:

Article

Association of ATM Gene Polymorphism with PTC Metastasis in Female Patients.

Published in:

International Journal of Endocrinology, 2014, p. 1, doi. 10.1155/2014/370825

By:

Yulu Gu;
Xiaoli Liu;
Yaqin Yu;
Jieping Shi;
Lizhe Ai;
Hui Sun;
Joseph Sam;
Kanu;
Chong Wang;
Yawen Liu

Publication type:

Article

Evaluation of ATM protein expression in canine mammary tumors.

Published in:

BMC Proceedings, 2013, v. 7, n. Suppl 2, p. 1, doi. 10.1186/1753-6561-7-S2-P68

By:

Raposo, Talita M. M.;
Fonseca-Alves, Carlos E.;
Terra, Erika M.;
Bueno, Renata C.;
Rogatto, Silvia R.;
Laufer-Amorim, Renée

Publication type:

Article

ATM polymorphisms IVS24-9delT, IVS38-8T>C, and 5557G>A in Mexican women with familial and/or early-onset breast cancer.

Published in:

Salud Pública de México, 2014, v. 56, n. 2, p. 206

By:

Calderón-Zúñiga, Fabiola del Carmen;
Ocampo-Gómez, Guadalupe;
López-Márquez, Francisco Carlos;
Recio-Vega, Rogelio;
Serrano-Gallardo, Luis Benjamín;
Ruiz-Flores, Pablo

Publication type:

Article

ATM Expression and Activation in Ataxia Telangiectasia Patients with and without Class Switch Recombination Defects.

Published in:

Journal of Clinical Immunology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10875-025-01857-3

By:

Salami, Fereshte;
Shad, Tannaz Moeini;
Fathi, Nazanin;
Mojtahedi, Hanieh;
Esmaeili, Marzie;
Shahkarami, Sepideh;
Afrakoti, Ladan Gol Mohammad Pour;
Amirifar, Parisa;
Delavari, Samaneh;
Nosrati, Hassan;
Razavi, Azadehsadat;
Ranjouri, Mohammad Reza;
Yousefpour, Mahsa;
Esfahani, Zahra Hamidi;
Azizi, Gholamreza;
Ashrafi, Mahmoudreza;
Rezaei, Nima;
Yazdani, Reza;
Abolhassani, Hassan

Publication type:

Article

Characterization of Glioma Stem Cells Through Multiple Stem Cell Markers and Their Specific Sensitization to Double-Strand Break-Inducing Agents by Pharmacological Inhibition of Ataxia Telangiectasia Mutated Protein.

Published in:

Brain Pathology, 2012, v. 22, n. 5, p. 677, doi. 10.1111/j.1750-3639.2012.00566.x

By:

Raso, Alessandro;
Vecchio, Donatella;
Cappelli, Enrico;
Ropolo, Monica;
Poggi, Alessandro;
Nozza, Paolo;
Biassoni, Roberto;
Mascelli, Samantha;
Capra, Valeria;
Kalfas, Fotios;
Severi, Paolo;
Frosina, Guido

Publication type:

Article

Nickel nanoparticle-induced cell transformation: involvement of DNA damage and DNA repair defect through HIF-1α/miR-210/Rad52 pathway.

Published in:

Journal of Nanobiotechnology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12951-021-01117-7

By:

Mo, Yiqun;
Zhang, Yue;
Zhang, Yuanbao;
Yuan, Jiali;
Mo, Luke;
Zhang, Qunwei

Publication type:

Article

The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes.

Published in:

PLoS Genetics, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pgen.1005017

By:

Pacheco, Sarai;
Marcet-Ortega, Marina;
Lange, Julian;
Jasin, Maria;
Keeney, Scott;
Roig, Ignasi

Publication type:

Article

An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence.

Published in:

PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003702

By:

Zhou, Zhong-Wei;
Liu, Cong;
Li, Tang-Liang;
Bruhn, Christopher;
Krueger, Anja;
Min, WooKee;
Wang, Zhao-Qi;
Carr, Antony M.

Publication type:

Article

Radiofrequency ablation triggers the migration of hepatocellular carcinoma cells by suppressing miR-148a-5p.

Published in:

Biological Chemistry, 2020, v. 401, n. 8, p. 985, doi. 10.1515/hsz-2020-0130

By:

Wang, Haicun;
Cao, Yang;
Hu, Kaiwen;
Li, Quanwang;
Yang, Yufei;
Wang, Lanrong;
Qin, Xiaoyan;
Qiao, Bingli;
Cheng, Liuqi;
Li, Peipei;
Dui, Weihua

Publication type:

Article

ATM knock out alters calcium signalling and augments contraction in skeletal muscle cells differentiated from human urine-derived stem cells.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02485-x

By:

Dematteis, Giulia;
Lecchi, Giulia;
Boni, Giulia;
Pendin, Diana;
Distasi, Carla;
Grilli, Mariagrazia;
Lim, Dmitry;
Fresu, Luigia Grazia;
Talmon, Maria

Publication type:

Article

Markers of macrophage infiltration and measures of lipolysis in human abdominal adipose tissues.

Published in:

Obesity (19307381), 2013, v. 21, n. 11, p. 2342, doi. 10.1002/oby.20341

By:

Michaud, Andréanne;
Pelletier, Mélissa;
Noël, Suzanne;
Bouchard, Céline;
Tchernof, André

Publication type:

Article

2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line.

Published in:

Annals of Agricultural & Environmental Medicine, 2024, v. 31, n. 1, p. 37, doi. 10.26444/aaem/174919

By:

Adamczuk, Grzegorz;
Humeniuk, Ewelina;
Adamczuk, Kamila;
Grabarska, Aneta;
Madej-Czerwonka, Barbara;
Michalczuk, Mariola;
Korga-Plewko, Agnieszka;
Dudka, Jarosław

Publication type:

Article

Endonuclease G initiates DNA rearrangements at the MLL breakpoint cluster upon replication stress.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3391, doi. 10.1038/onc.2014.268

By:

Gole, B;
Baumann, C;
Mian, E;
Ireno, C I;
Wiesmüller, L

Publication type:

Article

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

Published in:

Oncogene, 2015, v. 34, n. 25, p. 3336, doi. 10.1038/onc.2014.266

By:

Thomas, A;
Perry, T;
Berhane, S;
Oldreive, C;
Zlatanou, A;
Williams, L R;
Weston, V J;
Stankovic, T;
Kearns, P;
Pors, K;
Grand, R J;
Stewart, G S

Publication type:

Article

BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation.

Published in:

Oncogene, 2015, v. 34, n. 23, p. 3063, doi. 10.1038/onc.2014.235

By:

Wei, F;
Ojo, D;
Lin, X;
Wong, N;
He, L;
Yan, J;
Xu, S;
Major, P;
Tang, D

Publication type:

Article

CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress.

Published in:

Oncogene, 2015, v. 34, n. 23, p. 2978, doi. 10.1038/onc.2014.248

By:

Sarmento, L M;
Póvoa, V;
Nascimento, R;
Real, G;
Antunes, I;
Martins, L R;
Moita, C;
Alves, P M;
Abecasis, M;
Moita, L F;
Parkhouse, R M E;
Meijerink, J P P;
Barata, J T

Publication type:

Article

TACC3 deregulates the DNA damage response and confers sensitivity to radiation and PARP inhibition.

Published in:

Oncogene, 2015, v. 34, n. 13, p. 1667, doi. 10.1038/onc.2014.105

By:

Ha, G-H;
Kim, J-L;
Petersson, A;
Oh, S;
Denning, M F;
Patel, T;
Breuer, E-K

Publication type:

Article

The p53 pathway induction is not primarily dependent on Ataxia Telangiectasia Mutated (ATM) gene activity after fludarabine treatment in chronic lymphocytic leukemia cells.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 8, p. 1840, doi. 10.3109/10428194.2013.796056

By:

Navrkalova, Veronika;
Sebejova, Ludmila;
Zemanova, Jana;
Jaskova, Zuzana;
Trbusek, Martin

Publication type:

Article

Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 8, p. 1849, doi. 10.3109/10428194.2013.796058

By:

te Raa, G. Doreen;
Malcikova, Jitka;
Pospisilova, Sarka;
Trbusek, Martin;
Mraz, Mark;
Garff-Tavernier, Maria Le;
Merle-Béral, Hélène;
Lin, Ke;
Pettitt, Andrew R.;
Merkel, Olaf;
Stankovic, Tatjana;
van Oers, Marinus H.;
Eldering, Eric;
Stilgenbauer, Stephan;
Zenz, Thorsten;
Kater, Arnon P.

Publication type:

Article

Cell Death and Survival Pathways Involving ATM Protein Kinase.

Published in:

Genes, 2021, v. 12, n. 10, p. 1581, doi. 10.3390/genes12101581

By:

Aki, Toshihiko;
Uemura, Koichi

Publication type:

Article

Mechanisms Underlying the Suppression of Chromosome Rearrangements by Ataxia-Telangiectasia Mutated.

Published in:

Genes, 2021, v. 12, n. 8, p. 1232, doi. 10.3390/genes12081232

By:

Yamauchi, Motohiro

Publication type:

Article

Mec1/ATR, the Program Manager of Nucleic Acids Inc.

Published in:

Genes, 2017, v. 8, n. 1, p. 10, doi. 10.3390/genes8010010

By:

Feng, Wenyi

Publication type:

Article

ATM/CHK/p53 Pathway Dependent Chemopreventive and Therapeutic Activity on Lung Cancer by Pterostilbene.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0162335

By:

Lee, Hani;
Kim, Yonghwan;
Jeong, Ji Hye;
Ryu, Jae-Ha;
Kim, Woo-Young

Publication type:

Article