Works about ARTEMISININ derivatives

Results: 304

Genomics illuminates parasite biology.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 11, p. 727, doi. 10.1038/nrmicro3368

By:

Foth, Bernardo J.;
Otto, Thomas D.

Publication type:

Article

Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia.

Published in:

2020

By:

Watts, Rebecca E.;
Odedra, Anand;
Marquart, Louise;
Webb, Lachlan;
Abd-Rahman, Azrin N.;
Cascales, Laura;
Chalon, Stephan;
Rebelo, Maria;
Pava, Zuleima;
Collins, Katharine A.;
Pasay, Cielo;
Chen, Nanhua;
Peatey, Christopher L.;
Möhrle, Jörg J.;
McCarthy, James S.

Publication type:

journal article

Dihydroartemisinin Targets the NFIC/FBN1 Cascade to Enhance Wound Healing in Chronic Skin Ulcer by Inhibiting Fibroblast Ferroptosis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 5, p. 1, doi. 10.1002/jbt.70297

By:

Wei, Zhiyi;
Wang, Biao;
Fang, Xiangjian;
Cheng, Juntao

Publication type:

Article

A combination of Dihydroartemisinin and Venetoclax enhances antitumor effect in AML via C-MYC/BCL-XL/MCL-1 triple targeting.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02242-7

By:

Li, Fenglin;
Chen, Yao;
Zhuang, Haihui;
Pei, Renzhi;
Lu, Yuyu;
chen, Dong;
Li, Shuangyue;
Ye, Peipei;
lian, Jiaying;
Lu, Ying

Publication type:

Article

New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells.

Published in:

2022

By:

Lin, Lixian;
Tang, Zengqi;
Shi, Zhenrui;
Guo, Qing;
Xiong, Hui

Publication type:

journal article

Progress in nano-drug delivery of artemisinin and its derivatives: towards to use in immunomodulatory approaches.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. S611, doi. 10.1080/21691401.2018.1505739

By:

Charlie-Silva, Ives;
Fraceto, Leonardo Fernandes;
de Melo, Nathalie Ferreira Silva

Publication type:

Article

Dihydroartemisinin ameliorated the inflammatory response and regulated miRNA-mRNA expression profile of chronic nonbacterial prostatitis.

Published in:

Advances in Clinical & Experimental Medicine, 2024, v. 33, n. 8, p. 817, doi. 10.17219/acem/172386

By:

Jie Hu;
Yan Zhou;
Junhao Wang;
Jianpeng Han;
Jianyong Feng;
Wenbin Chen;
Kuo Guo;
Yongzhang Li

Publication type:

Article

Alternatives to currently used antimalarial drugs: in search of a magic bullet.

Published in:

Infectious Diseases of Poverty, 2016, v. 5, p. 1, doi. 10.1186/s40249-016-0196-8

By:

Bhagavathula, Akshaya Srikanth;
Elnour, Asim Ahmed;
Shehab, Abdulla

Publication type:

Article

From malaria fighter to diabetes guardian: the emerging role of artesunate in treating diabetes and diabetic complications.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1583575

By:

Li, Dongze;
Liang, Qingyue;
Xu, Linghao;
Zhang, Li;
Gong, Qiming;
Zhou, Tingting;
Luo, Changfang;
Huang, Wei;
Yang, Yuan

Publication type:

Article

Multiscale screening and identifying specific targets for artesunate in suppressing bladder cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1584502

By:

Yuan, Yi;
Chu, Guangdi;
Ma, Qingyue;
Liang, Zhijuan;
Liang, Ye;
Niu, Haitao

Publication type:

Article

Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00711

By:

Kadioglu, Onat;
Ariel Chan;
Cong Ling Qiu, Alena;
Kam Wai Wong, Vincent;
Colligs, Vanessa;
Wecklein, Sabine;
Rached, Halima Freund-Henni;
Efferth, Thomas;
Wen-Luan Wendy Hsiao

Publication type:

Article

The Ototoxicity of Antimalarial Drugs—A State of the Art Review.

Published in:

Frontiers in Neurology, 2021, v. 11, p. N.PAG, doi. 10.3389/fneur.2021.661740

By:

Jozefowicz-Korczynska, Magdalena;
Pajor, Anna;
Lucas Grzelczyk, Weronika

Publication type:

Article

Effects of dihydroartemisinin on the gut microbiome of mice.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 2, p. 707, doi. 10.3892/mmr.2020.11165

By:

Liu, Yanyan;
Yang, Yanhong;
Lei, Yuting;
Yang, Lanxiang;
Zhang, Xueying;
Yuan, Jian;
Lei, Zili

Publication type:

Article

Dihydroartemisinin inhibits multiplication of Brucella suis vaccine strain 2 in murine microglia BV2 cells via stimulation of caspase-dependent apoptosis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 5, p. 4067, doi. 10.3892/mmr.2019.10672

By:

Yang, Juan;
Li, Haining;
Wang, Zhao;
Yu, Liming;
Liu, Qiang;
Niu, Xiaoyan;
Xu, Ting;
Wang, Zhenhai

Publication type:

Article

Artesunate exerts protective effects against ulcerative colitis via suppressing Toll-like receptor 4 and its downstream nuclear factor-κB signaling pathways.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 2, p. 1321, doi. 10.3892/mmr.2019.10345

By:

Chen, Yu-Xuan;
Zhang, Xiao-Qi;
Yu, Cheng-Gong;
Huang, Shu-Ling;
Xie, Ying;
Dou, Xiao-Tan;
Liu, Wen-Jia;
Zou, Xiao-Ping

Publication type:

Article

Suspected Artesunate Resistant Malaria in South India.

Published in:

2018

By:

Akunuri, Shalini;
Shraddha, Pandey;
Palli, Vedita;
MuraliSantosh, Buddha

Publication type:

Case Study

Antimalarial Drugs Used in the Management of Viral Infections-A Perspective.

Published in:

Indian Journal of Forensic Medicine & Toxicology, 2020, v. 14, n. 4, p. 4828, doi. 10.37506/ijfmt.v14i4.12395

By:

Reethega L.;
Lakshmi T.;
Geetha, R. V.

Publication type:

Article

Cocrystallization of Artemisinin and Amodiaquine Hydrochloride.

Published in:

Thai Journal of Pharmaceutical Sciences, 2015, v. 39, n. 4, p. 141

By:

Sirikun, Wiriyaporn;
Chatchawalsaisin, Jittima;
Sutanthavibul, Narueporn

Publication type:

Article

Comparative efficacy and safety of the artemisinin derivatives compared to quinine for treating severe malaria in children and adults: A systematic update of literature and network meta-analysis.

Published in:

PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0269391

By:

Nyaaba, Nicholas;
Andoh, Nana Efua;
Amoh, Gordon;
Amuzu, Dominic Selorm Yao;
Ansong, Mary;
Ordóñez-Mena, José M.;
Hirst, Jennifer

Publication type:

Article

Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Sub-Saharan Africa: A systematic review and meta-analysis.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0264339

By:

Marwa, Karol;
Kapesa, Anthony;
Baraka, Vito;
Konje, Evelyne;
Kidenya, Benson;
Mukonzo, Jackson;
Kamugisha, Erasmus;
Swedberg, Gote

Publication type:

Article

Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-κB Activation in Microglial Cells.

Published in:

Inflammation, 2015, v. 38, n. 5, p. 1925, doi. 10.1007/s10753-015-0172-7

By:

Wang, Dunjing;
Shi, Jun;
Lv, Shuiqing;
Xu, Weiwei;
Li, Jizhen;
Ge, Wei;
Xiao, Chenghua;
Geng, Deqin;
Liu, Yonghai

Publication type:

Article

EDA, EDAR, EDARADD and WNT10A allelic variants in patients with ectodermal derivative impairment in the Spanish population.

Published in:

2019

By:

Martínez-Romero, María Carmen;
Ballesta-Martínez, María Juliana;
López-González, Vanesa;
Sánchez-Soler, María José;
Serrano-Antón, Ana Teresa;
Barreda-Sánchez, María;
Rodriguez-Peña, Lidya;
Martínez-Menchon, María Teresa;
Frías-Iniesta, José;
Sánchez-Pedreño, Paloma;
Carbonell-Meseguer, Pablo;
Glover-López, Guillermo;
Guillén-Navarro, Encarna;
GIEDE (Spanish multidisciplinary research group for ectodermal dysplasia);
Alcalá-García, Rebeca;
Barcia-Ramírez, Ana;
Cruz-Rojo, Jaime;
Gener-Querol, Blanca;
Hernández-Martín, Angela;
Lapunzina-Badía, Pablo

Publication type:

journal article

IMPROVEMENT OF THE HPLC DETERMINATION CONDITION FOR ARTEMISININ AND ITS DERIVATIVES.

Published in:

Journal of Liquid Chromatography & Related Technologies, 2012, v. 35, n. 12, p. 1712, doi. 10.1080/10826076.2011.621498

By:

Wang, Yun;
Liu, Jian-Kun

Publication type:

Article

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle.

Published in:

PLoS Genetics, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pgen.1008453

By:

Li, Xue;
Kumar, Sudhir;
McDew-White, Marina;
Haile, Meseret;
Cheeseman, Ian H.;
Emrich, Scott;
Button-Simons, Katie;
Nosten, François;
Kappe, Stefan H. I.;
Ferdig, Michael T.;
Anderson, Tim J. C.;
Vaughan, Ashley M.

Publication type:

Article

An Artemisinin‐Derivative–(NHC)Gold(I) Hybrid with Enhanced Cytotoxicity through Inhibition of NRF2 Transcriptional Activity.

Published in:

Angewandte Chemie, 2020, v. 132, n. 29, p. 12160, doi. 10.1002/ange.202002992

By:

Zhang, Chen;
Fortin, Pierre‐Yves;
Barnoin, Guillaume;
Qin, Xue;
Wang, Xing;
Fernandez Alvarez, Alvaro;
Bijani, Christian;
Maddelein, Marie‐Lise;
Hemmert, Catherine;
Cuvillier, Olivier;
Gornitzka, Heinz

Publication type:

Article

ART714 is a best-in-class antileukemic 2-carbon-linked dimeric artemisinin derivative.

Published in:

Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 1, p. 39, doi. 10.1007/s00280-023-04539-2

By:

Kagan, Amanda B.;
Moses, Blake S.;
Lapidus, Rena;
Mott, Bryan T.;
Rai, Ganesha;
Anders, Nicole M.;
Hoag, Stephen W.;
Rudek, Michelle A.;
Civin, Curt I.

Publication type:

Article

Artemisinin-type drugs for the treatment of hematological malignancies.

Published in:

2021

By:

Mancuso, R. I.;
Foglio, M. A.;
Olalla Saad, S. T.

Publication type:

journal article

Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation.

Published in:

Archives of Toxicology, 2021, v. 95, n. 7, p. 2485, doi. 10.1007/s00204-021-03058-4

By:

Kadioglu, Onat;
Klauck, Sabine M.;
Fleischer, Edmond;
Shan, Letian;
Efferth, Thomas

Publication type:

Article

Oral Artesunate–Amodiaquine and Artemether–Lumefantrine in the Treatment of Uncomplicated Hyperparasitaemic Plasmodium falciparum Malaria in Children.

Published in:

Journal of Tropical Pediatrics, 2012, v. 58, n. 2, p. 151, doi. 10.1093/tropej/fmr045

By:

Gbotosho, Grace O.;
Sowunmi, Akintunde;
Okuboyejo, Titilope M.;
Happi, Christian T.

Publication type:

Article

Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-β1/Smad pathway in MN mice.

Published in:

Renal Failure, 2023, v. 45, n. 1, p. 1, doi. 10.1080/0886022X.2022.2120821

By:

Li, Yongzhang;
Chen, Suzhi;
Tan, Jinchuan;
Zhou, Yan;
Ren, Meifang;
Zhang, Qian;
Zhao, Meijiao;
Yuan, Guodong;
Zhang, Wenxi;
Yang, Fengwen

Publication type:

Article

Evaluation of antineoplastic activity of artemisinin-derived trioxanes in canine tumors.

Published in:

Japanese Journal of Veterinary Research, 2013, v. 61, n. 3, p. 125

By:

Kenji Hosoya

Publication type:

Article

Induction of autophagy and autophagy‐dependent apoptosis in diffuse large B‐cell lymphoma by a new antimalarial artemisinin derivative, SM1044.

Published in:

Cancer Medicine, 2018, v. 7, n. 2, p. 380, doi. 10.1002/cam4.1276

By:

Cheng, Chunyan;
Wang, Tao;
Song, Zhiqun;
Peng, Lijun;
Gao, Mengqing;
Hermine, Olivier;
Rousseaux, Sophie;
Khochbin, Saadi;
Mi, Jian‐Qing;
Wang, Jin

Publication type:

Article

Correction: New clinical application prospects of artemisinin and its derivatives: a scoping review.

Published in:

Infectious Diseases of Poverty, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40249-024-01180-w

By:

Huang, Yangmu;
Yang, Yang;
Liu, Guangqi;
Xu, Ming

Publication type:

Article

New clinical application prospects of artemisinin and its derivatives: a scoping review.

Published in:

2023

By:

Huang, Yangmu;
Yang, Yang;
Liu, Guangqi;
Xu, Ming;
Hu, Dan

Publication type:

Literature Review

Artesunate Inhibits Metastatic Potential in Cisplatin-Resistant Bladder Cancer Cells by Altering Integrins.

Published in:

Cells (2073-4409), 2025, v. 14, n. 8, p. 570, doi. 10.3390/cells14080570

By:

Vakhrusheva, Olesya;
Zhao, Fuguang;
Markowitsch, Sascha Dennis;
Slade, Kimberly Sue;
Brandt, Maximilian Peter;
Tsaur, Igor;
Cinatl Jr., Jindrich;
Michaelis, Martin;
Efferth, Thomas;
Blaheta, Roman Alexander;
Haferkamp, Axel;
Juengel, Eva

Publication type:

Article

Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction.

Published in:

Cells (2073-4409), 2020, v. 9, n. 12, p. 2643, doi. 10.3390/cells9122643

By:

Zhao, Fuguang;
Vakhrusheva, Olesya;
Markowitsch, Sascha D.;
Slade, Kimberly S.;
Tsaur, Igor;
Cinatl Jr., Jindrich;
Michaelis, Martin;
Efferth, Thomas;
Haferkamp, Axel;
Juengel, Eva

Publication type:

Article

AaWRKY9 contributes to light‐ and jasmonate‐mediated to regulate the biosynthesis of artemisinin in Artemisia annua.

Published in:

New Phytologist, 2021, v. 231, n. 5, p. 1858, doi. 10.1111/nph.17453

By:

Fu, Xueqing;
Peng, Bowen;
Hassani, Danial;
Xie, Lihui;
Liu, Hang;
Li, Yongpeng;
Chen, Tiantian;
Liu, Pin;
Tang, Yueli;
Li, Ling;
Zhao, Jingya;
Sun, Xiaofen;
Tang, Kexuan

Publication type:

Article

An R2R3-MYB Transcription Factor Positively Regulates the Glandular Secretory Trichome Initiation in Artemisia annua L.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. N.PAG, doi. 10.3389/fpls.2021.657156

By:

Qin, Wei;
Xie, Lihui;
Li, Yongpeng;
Liu, Hang;
Fu, Xueqing;
Chen, Tiantian;
Hassani, Danial;
Li, Ling;
Sun, Xiaofen;
Tang, Kexuan

Publication type:

Article

Repositioning of Antiparasitic Drugs for Tumor Treatment.

Published in:

Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.670804

By:

Li, Yan-Qi;
Zheng, Zhi;
Liu, Quan-Xing;
Lu, Xiao;
Zhou, Dong;
Zhang, Jiao;
Zheng, Hong;
Dai, Ji-Gang

Publication type:

Article

Severe Malaria Not Responsive to Artemisinin Derivatives in Man Returning from Angola to Vietnam.

Published in:

Emerging Infectious Diseases, 2014, v. 20, n. 7, p. 1199, doi. 10.3201/eid2007.140155

By:

Nguyen Van Hong;
Amambua-Ngwa, Alfred;
Nguyen Quang Tuan;
Do Duy Cuong;
Nguyen Thi Huong Giang;
Nguyen Van Dung;
Ta Thi Tinh;
Nguyen Van Tien;
Bui Quang Phuc;
Tran Thanh Duong;
Rosanas-Urgell, Anna;
D'Alessandro, Umberto;
Van Geertruyden, Jean-Pierre;
Erhart, Annette

Publication type:

Article

Antimalarial agent artesunate induces G0/G1 cell cycle arrest and apoptosis via increasing intracellular ROS levels in normal liver cells.

Published in:

Human & Experimental Toxicology, 2020, v. 39, n. 12, p. 1681, doi. 10.1177/0960327120937331

By:

Yin, S;
Yang, H;
Zhao, X;
Wei, S;
Tao, Y;
Liu, M;
Bo, R;
Li, J

Publication type:

Article

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24814-1

By:

Zhang, Min;
Wang, Chengqi;
Oberstaller, Jenna;
Thomas, Phaedra;
Otto, Thomas D.;
Casandra, Debora;
Boyapalle, Sandhya;
Adapa, Swamy R.;
Xu, Shulin;
Button-Simons, Katrina;
Mayho, Matthew;
Rayner, Julian C.;
Ferdig, Michael T.;
Jiang, Rays H. Y.;
Adams, John H.

Publication type:

Article

Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites.

Published in:

Pharmaceutics, 2023, v. 15, n. 10, p. 2440, doi. 10.3390/pharmaceutics15102440

By:

Reyser, Thibaud;
Paloque, Lucie;
Nguyen, Michel;
Augereau, Jean-Michel;
Fuchter, Matthew John;
Lopez, Marie;
Arimondo, Paola B.;
Hassell-Hart, Storm;
Spencer, John;
Di Stefano, Luisa;
Benoit-Vical, Françoise

Publication type:

Article

Molecular Hybridization as a Strategy for Developing Artemisinin-Derived Anticancer Candidates.

Published in:

Pharmaceutics, 2023, v. 15, n. 9, p. 2185, doi. 10.3390/pharmaceutics15092185

By:

Marchesi, Elena;
Perrone, Daniela;
Navacchia, Maria Luisa

Publication type:

Article

Recent Advances in the Therapeutic Efficacy of Artesunate.

Published in:

Pharmaceutics, 2022, v. 14, n. 3, p. 504, doi. 10.3390/pharmaceutics14030504

By:

Ruwizhi, Ngonidzashe;
Maseko, Rejoice Bethusile;
Aderibigbe, Blessing Atim

Publication type:

Article

Prevalence of Mutations in the pfcoronin Gene and Association with Ex Vivo Susceptibility to Common Quinoline Drugs against Plasmodium falciparum.

Published in:

Pharmaceutics, 2021, v. 13, n. 8, p. 1273, doi. 10.3390/pharmaceutics13081273

By:

Delandre, Océane;
Gendrot, Mathieu;
Fonta, Isabelle;
Mosnier, Joel;
Benoit, Nicolas;
Amalvict, Rémy;
Gomez, Nicolas;
Madamet, Marylin;
Pradines, Bruno

Publication type:

Article

Nanoparticles Formulations of Artemisinin and Derivatives as Potential Therapeutics for the Treatment of Cancer, Leishmaniasis and Malaria.

Published in:

Pharmaceutics, 2020, v. 12, n. 8, p. 748, doi. 10.3390/pharmaceutics12080748

By:

Alven, Sibusiso;
Aderibigbe, Blessing Atim

Publication type:

Article

Oral Administration of Artemisone for the Treatment of Schistosomiasis: Formulation Challenges and In Vivo Efficacy.

Published in:

Pharmaceutics, 2020, v. 12, n. 6, p. 509, doi. 10.3390/pharmaceutics12060509

By:

Zech, Johanna;
Gold, Daniel;
Salaymeh, Nadeen;
Sasson, Netanel Cohen;
Rabinowitch, Ithai;
Golenser, Jacob;
Mäder, Karsten

Publication type:

Article

Artemisinin and Its Derivatives: Promising Therapeutic Agents for Age-Related Macular Degeneration.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 4, p. 535, doi. 10.3390/ph18040535

By:

Liu, Chun;
Liu, Xiaoqin;
Duan, Junguo

Publication type:

Article

Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic Variants.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 129, doi. 10.3390/ph15020129

By:

Badraoui, Riadh;
Saoudi, Mongi;
Hamadou, Walid S.;
Elkahoui, Salem;
Siddiqui, Arif J.;
Alam, Jahoor M.;
Jamal, Arshad;
Adnan, Mohd;
Suliemen, Abdel M. E.;
Alreshidi, Mousa M.;
Yadav, Dharmendra K.;
Naïli, Houcine;
Ben-Nasr, Hmed

Publication type:

Article