Works matching DE "ARRESTINS"

Results: 457

GPCR kinases phosphorylate GPCR C-terminal peptides in a hierarchical manner.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08301-7

By:

Löbbert, Arnelle;
Lorz, Nils;
Matthees, Edda S. F.;
Rößler, Philip;
Hoffmann, Carsten;
Gossert, Alvar D.

Publication type:

Article

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 362, doi. 10.1038/nsmb.3014

By:

Kroeze, Wesley K;
Sassano, Maria F;
Huang, Xi-Ping;
Lansu, Katherine;
McCorvy, John D;
Giguère, Patrick M;
Sciaky, Noah;
Roth, Bryan L

Publication type:

Article

Influence of Arrestin on the Photodecay of Bovine Rhodopsin.

Published in:

Angewandte Chemie, 2015, v. 127, n. 46, p. 13759, doi. 10.1002/ange.201505798

By:

Chatterjee, Deep;
Eckert, Carl Elias;
Slavov, Chavdar;
Saxena, Krishna;
Fürtig, Boris;
Sanders, Charles R.;
Gurevich, Vsevolod V.;
Wachtveitl, Josef;
Schwalbe, Harald

Publication type:

Article

Divergent roles of DRY and NPxxY motifs in selective activation of downstream signalling by the apelin receptor.

Published in:

Biochemical Journal, 2024, v. 481, n. 23, p. 1707, doi. 10.1042/BCJ20240320

By:

Murali, Subhashree;
Aradhyam, Gopala Krishna

Publication type:

Article

APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells.

Published in:

Biochemical Journal, 2022, v. 479, n. 3, p. 385, doi. 10.1042/BCJ20210813

By:

Yingying Liu;
Xiaochuan Ma;
Hui Yang;
Xun Li;
Yingli Ma;
Ason, Brandon;
Suling Liu;
Hu, Liaoyuan A.

Publication type:

Article

Loss of APJ mediated &@946;-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice.

Published in:

Biochemical Journal, 2020, v. 477, n. 17, p. 3313, doi. 10.1042/BCJ20200343

By:

Na Li;
Xiaochuan Ma;
Ting Ban;
Shaohua Xu;
Yingli Ma;
Ason, Brandon;
Hu, Liaoyuan A.

Publication type:

Article

Carvedilol targets β-arrestins to rewire innate immunity and improve oncolytic adenoviral therapy.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03041-4

By:

Hoare, Joseph I.;
Osmani, Bleona;
O'Sullivan, Emily A.;
Browne, Ashley;
Campbell, Nicola;
Metcalf, Stephen;
Nicolini, Francesco;
Saxena, Jayeta;
Martin, Sarah A.;
Lockley, Michelle

Publication type:

Article

Biased action of the CXCR4-targeting drug plerixafor is essential for its superior hematopoietic stem cell mobilization.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02070-9

By:

Jørgensen, Astrid S.;
Daugvilaite, Viktorija;
De Filippo, Katia;
Berg, Christian;
Mavri, Masa;
Benned-Jensen, Tau;
Juzenaite, Goda;
Hjortø, Gertrud;
Rankin, Sara;
Våbenø, Jon;
Rosenkilde, Mette M.

Publication type:

Article

The Regulations of Drosophila Phototransduction.

Published in:

Journal of Neurogenetics, 2012, v. 26, n. 2, p. 144, doi. 10.3109/01677063.2011.650253

By:

Leung, Hung-Tat;
Shino, Shikoh;
Kim, Eunju

Publication type:

Article

Downstream signalling of the disease‐associated mutations on GPR56/ADGRG1.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 4, p. 331, doi. 10.1111/bcpt.13873

By:

Cevheroğlu, Orkun;
Demir, Nil;
Kesici, Mehmet Seçkin;
Özçubukçu, Salih;
Son, Çağdaş D.

Publication type:

Article

Pharmacology and function of the orphan GPR139 G protein‐coupled receptor.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, p. 35, doi. 10.1111/bcpt.13263

By:

Vedel, Line;
Nøhr, Anne Cathrine;
Gloriam, David E.;
Bräuner‐Osborne, Hans

Publication type:

Article

Constitutive internalization across therapeutically targeted GPCRs correlates with constitutive activity.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, p. 116, doi. 10.1111/bcpt.13274

By:

Hendrik Schmidt, Jan;
Perslev, Mathias;
Bukowski, Lina;
Stoklund, Mikkel;
Herborg, Freja;
Herlo, Rasmus;
Lindegaard Madsen, Kenneth

Publication type:

Article

Emerging roles of striatal dopamine D2 receptors in motivated behaviour: Implications for psychiatric disorders.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, p. 47, doi. 10.1111/bcpt.13271

By:

Olivetti, Pedro R.;
Balsam, Peter D.;
Simpson, Eleanor H.;
Kellendonk, Christoph

Publication type:

Article

Apelin peptides linked to anti‐serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, p. 96, doi. 10.1111/bcpt.13227

By:

Read, Cai;
Yang, Peiran;
Kuc, Rhoda E.;
Nyimanu, Duuamene;
Williams, Thomas L.;
Glen, Robert C.;
Holt, Lucy J.;
Arulanantham, Haren;
Smart, Andrew;
Davenport, Anthony P.;
Maguire, Janet J.

Publication type:

Article

Position Review: Functional Selectivity in Mammalian Olfactory Receptors.

Published in:

Chemical Senses, 2020, v. 45, n. 7, p. 503, doi. 10.1093/chemse/bjaa046

By:

Ache, Barry W

Publication type:

Article

A Drosophila Nonvisual Arrestin Is Required for the Maintenance of Olfactory Sensitivity.

Published in:

Chemical Senses, 2006, v. 31, n. 1, p. 49, doi. 10.1093/chemse/bjj005

By:

Ge, Hong;
Krishnan, Parthasarathy;
Liu, Lingzhi;
Krishnan, Balaji;
Davis, Ronald L.;
Hardin, Paul E.;
Roman, Gregg

Publication type:

Article

The Old and New Visions of Biased Agonism Through the Prism of Adenosine Receptor Signaling and Receptor/Receptor and Receptor/Protein Interactions.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.628601

By:

Franco, Rafael;
Rivas‐Santisteban, Rafael;
Reyes-Resina, Irene;
Navarro, Gemma

Publication type:

Article

In Silico , In Vitro and In Vivo Pharmacodynamic Characterization of Novel Analgesic Drug Candidate Somatostatin SST<sub>4</sub> Receptor Agonists.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.601887

By:

Kántás, Boglárka;
Szőke, Éva;
Börzsei, Rita;
Bánhegyi, Péter;
Asghar, Junaid;
Hudhud, Lina;
Steib, Anita;
Hunyady, Ágnes;
Horváth, Ádám;
Kecskés, Angéla;
Borbély, Éva;
Hetényi, Csaba;
Pethő, Gábor;
Pintér, Erika;
Helyes, Zsuzsanna

Publication type:

Article

The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.588669

By:

Read, Cai;
Nyimanu, Duuamene;
Yang, Peiran;
Kuc, Rhoda E.;
Williams, Thomas L.;
Fitzpatrick, Christopher M.;
Foster, Richard;
Glen, Robert C.;
Maguire, Janet J.;
Davenport, Anthony P.

Publication type:

Article

Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.600132

By:

Simões, Sarah C.;
Balico-Silva, André L.;
Parreiras-e-Silva, Lucas T.;
Bitencourt, André L. B.;
Bouvier, Michel;
Costa-Neto, Claudio M.

Publication type:

Article

Interplay Between Angiotensin II Type 1 Receptor and Thrombin Receptor Revealed by Bioluminescence Resonance Energy Transfer Assay.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01283

By:

Zamel, Isra Al;
Palakkott, Abdulrasheed;
Ashraf, Arshida;
Iratni, Rabah;
Ayoub, Mohammed Akli

Publication type:

Article

The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01271

By:

Al-Sabah, Suleiman;
Adi, Lobna;
Bünemann, Moritz;
Krasel, Cornelius

Publication type:

Article

Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00188

By:

Bedini, Andrea;
Di Cesare Mannelli, Lorenzo;
Micheli, Laura;
Baiula, Monica;
Vaca, Gabriela;
De Marco, Rossella;
Gentilucci, Luca;
Ghelardini, Carla;
Spampinato, Santi

Publication type:

Article

Desmetramadol Is Identified as a G-Protein Biased µ Opioid Receptor Agonist.

Published in:

Frontiers in Pharmacology, 2020, v. 10, p. 1, doi. 10.3389/fphar.2019.01680

By:

Zebala, John A.;
Schuler, Aaron D.;
Kahn, Stuart J.;
Maeda, Dean Y.

Publication type:

Article

Arrestin2 modulates androgen receptor activation.

Published in:

Oncogene, 2015, v. 34, n. 24, p. 3144, doi. 10.1038/onc.2014.252

By:

Purayil, H T;
Zhang, Y;
Dey, A;
Gersey, Z;
Espana-Serrano, L;
Daaka, Y

Publication type:

Article

Interactive effects of ARRB2 and CHRNA5 genetic polymorphisms on cognitive function in Chinese male methamphetamine use disorder patients.

Published in:

American Journal on Addictions, 2025, v. 34, n. 3, p. 289, doi. 10.1111/ajad.13666

By:

Jiang, Linjun;
Wang, Dongmei;
Tian, Yang;
Chen, Jiajing;
Qu, Mengqian;
Chen, Han;
Huang, Ren;
Jia, Lianglun;
Fu, Fabing;
Tang, Shanshan;
Wang, Xiaotao;
Zhang, Xiang‐Yang

Publication type:

Article

Overexpression of GPR35 confers drug resistance in NSCLC cells by β-arrestin/Akt signaling.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 6249, doi. 10.2147/OTT.S175606

By:

Wang, Wei;
Han, Tianci;
Tong, Wei;
Zhao, Jian;
Qiu, Xueshan

Publication type:

Article

Critical role of the finger loop in arrestin binding to the receptors.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0213792

By:

Chen Zheng;
Tholen, Jonas;
Gurevich, Vsevolod V.

Publication type:

Article

Dissecting the roles of β-arrestin2 and GSK-3 signaling in 5-HT1BR-mediated perseverative behavior and prepulse inhibition deficits in mice.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211239

By:

Thompson, Summer L.;
Dulawa, Stephanie C.

Publication type:

Article

Investigation of Ldb19/Art1 localization and function at the late Golgi.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206944

By:

Martínez-Márquez, Jorge Y.;
Duncan, Mara C.

Publication type:

Article

β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0196946

By:

Shintani, Yusuke;
Hayata-Takano, Atsuko;
Moriguchi, Keita;
Nakazawa, Takanobu;
Ago, Yukio;
Kasai, Atsushi;
Seiriki, Kaoru;
Shintani, Norihito;
Hashimoto, Hitoshi

Publication type:

Article

Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1.

Published in:

Cellular & Molecular Neurobiology, 2021, v. 41, n. 5, p. 1059, doi. 10.1007/s10571-020-00973-5

By:

Narayan, Ankita;
Hunkele, Amanda;
Xu, Jin;
Bassoni, Daniel L.;
Pasternak, Gavril W.;
Pan, Ying-Xian

Publication type:

Article

Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway.

Published in:

Frontiers in Behavioral Neuroscience, 2017, v. 10, p. 1, doi. 10.3389/fnbeh.2016.00253

By:

Berríos-Cárcamo, Pablo;
Quintanilla, María E.;
Herrera-Marschitz, Mario;
Vasiliou, Vasilis;
Zapata-Torres, Gerald;
Rivera-Mez, Mario

Publication type:

Article

The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and β-arrestin signalling.

Published in:

Journal of Psychopharmacology, 2020, v. 34, n. 12, p. 1431, doi. 10.1177/0269881120959605

By:

Sałaciak, Kinga;
Głuch-Lutwin, Monika;
Siwek, Agata;
Szafarz, Małgorzata;
Kazek, Grzegorz;
Bednarski, Marek;
Nowiński, Leszek;
Mitchell, Emma;
Jastrzębska-Więsek, Magdalena;
Partyka, Anna;
Wesołowska, Anna;
Kołaczkowski, Marcin;
Szkaradek, Natalia;
Marona, Henryk;
Sapa, Jacek;
Pytka, Karolina

Publication type:

Article

Dexamethasone in the presence of desipramine enhances MAPK/ERK1/2 signaling possibly via its interference with β-arrestin.

Published in:

Journal of Neural Transmission, 2014, v. 121, n. 3, p. 289, doi. 10.1007/s00702-013-1099-5

By:

Lucki, Anat;
Klein, Ehud;
Karry, Rachel;
Ben-Shachar, Dorit

Publication type:

Article

?-arrestin 2 regulates A? generation and ?-secretase activity in Alzheimer's disease.

Published in:

Nature Medicine, 2013, v. 19, n. 1, p. 43, doi. 10.1038/nm.3023

By:

Thathiah, Amantha;
Horré, Katrien;
Snellinx, An;
Vandewyer, Elke;
Huang, Yunhong;
Ciesielska, Marta;
De Kloe, Gerdien;
Munck, Sebastian;
De Strooper, Bart

Publication type:

Article

PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 67, n. 5, p. 550, doi. 10.1165/rcmb.2021-0320OC

By:

Tompkins, Eric;
Mimic, Bogdana;
Cuevas-Mora, Karina;
Schorsch, Hannah;
Shah, Sushrut D.;
Deshpande, Deepak A.;
Benovic, Jeffrey L.;
Penn, Raymond B.;
Pera, Tonio

Publication type:

Article

The Role of Individual Residues in the N-Terminus of Arrestin-1 in Rhodopsin Binding.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 2, p. 715, doi. 10.3390/ijms26020715

By:

Vishnivetskiy, Sergey A.;
Paul, Trishita;
Gurevich, Eugenia V.;
Gurevich, Vsevolod V.

Publication type:

Article

Sequestration of Gβγ by deubiquitinated arrestins into the nucleus as a novel desensitization mechanism of G protein–coupled receptors.

Published in:

Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-022-01013-z

By:

Min, Xiao;
Sun, Ningning;
Wang, Shujie;
Zhang, Xiaohan;
Kim, Kyeong-Man

Publication type:

Article

Amphipols in G Protein-Coupled Receptor Pharmacology: What Are They Good For?

Published in:

Journal of Membrane Biology, 2014, v. 247, n. 9/10, p. 853, doi. 10.1007/s00232-014-9665-9

By:

Mary, Sophie;
Damian, Marjorie;
Rahmeh, Rita;
Mouillac, Bernard;
Marie, Jacky;
Granier, Sébastien;
Banères, Jean-Louis

Publication type:

Article

Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications.

Published in:

Pflügers Archiv: European Journal of Physiology, 2023, v. 475, n. 12, p. 1387, doi. 10.1007/s00424-023-02879-9

By:

Rodgers, Jessica;
Wright, Phillip;
Ballister, Edward R.;
Hughes, Rebecca B.;
Storchi, Riccardo;
Wynne, Jonathan;
Martial, Franck P.;
Lucas, Robert J.

Publication type:

Article

Role of G protein-regulated inducer of neurite outgrowth 3 (GRIN3) in β-arrestin 2-Akt signaling and dopaminergic behaviors.

Published in:

Pflügers Archiv: European Journal of Physiology, 2018, v. 470, n. 6, p. 937, doi. 10.1007/s00424-018-2124-1

By:

Mototani, Yasumasa;
Okamura, Tadashi;
Goto, Motohito;
Shimizu, Yukiko;
Yanobu-Takanashi, Rieko;
Ito, Aiko;
Kawamura, Naoya;
Yagisawa, Yuka;
Umeki, Daisuke;
Nariyama, Megumi;
Suita, Kenji;
Ohnuki, Yoshiki;
Shiozawa, Kouichi;
Sahara, Yoshinori;
Kozasa, Tohru;
Saeki, Yasutake;
Okumura, Satoshi

Publication type:

Article

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.

Published in:

Nature, 2015, v. 523, n. 7562, p. 561, doi. 10.1038/nature14656

By:

Kang, Yanyong;
Zhou, X. Edward;
Gao, Xiang;
He, Yuanzheng;
Liu, Wei;
Ishchenko, Andrii;
Barty, Anton;
White, Thomas A.;
Yefanov, Oleksandr;
Han, Gye Won;
Xu, Qingping;
de Waal, Parker W.;
Ke, Jiyuan;
Tan, M. H. Eileen;
Zhang, Chenghai;
Moeller, Arne;
West, Graham M.;
Pascal, Bruce D.;
Van Eps, Ned;
Caro, Lydia N.

Publication type:

Article

Structural biology: Arresting developments in receptor signalling.

Published in:

Nature, 2015, v. 523, n. 7562, p. 538, doi. 10.1038/nature14637

By:

Benovic, Jeffrey L.

Publication type:

Article

Non-Invasive Diagnostics of Renal Cell Carcinoma Using Ultrasensitive Immunodetection of Cancer-Retina Antigens.

Published in:

Biochemistry (00062979), 2022, v. 87, n. 7, p. 658, doi. 10.1134/S0006297922070070

By:

Shlyapnikov, Yuri M.;
Malakhova, Ekaterina A.;
Potoldykova, Natalia V.;
Svetocheva, Yana A.;
Vinarov, Andrei Z.;
Zinchenko, Dmitry V.;
Zernii, Evgeni Yu.;
Zamyatnin Jr., Andrey A.;
Shlyapnikova, Elena A.

Publication type:

Article

Conformational signatures in β-arrestin2 reveal natural biased agonism at a G-protein-coupled receptor.

Published in:

Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0134-3

By:

Reyes-Alcaraz, Arfaxad;
Lee, Yoo-Na;
Yun, Seongsik;
Hwang, Jong-Ik;
Seong, Jae Young

Publication type:

Article

Spare the Rod1, spoil transporter endocytosis.

Published in:

Journal of Cell Biology, 2012, v. 196, n. 2, p. 181, doi. 10.1083/jcb.1962if

By:

Leslie, Mitch

Publication type:

Article

Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.67478

By:

Crilly, Stephanie E.;
Wooree Ko;
Weinberg, Zara Y.;
Puthenveedu, Manojkumar A.

Publication type:

Article

Latrophilin GPCR signaling mediates synapse formation.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65717

By:

Sando, Richard;
Südhof, Thomas C.

Publication type:

Article

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.56519

By:

Uprety, Rajendra;
Tao Che;
Zaidi, Saheem A.;
Grinnell, Steven G.;
Varga, Balázs R.;
Faouzi, Abdelfattah;
Slocum, Samuel T.;
Allaoa, Abdullah;
Varadi, András;
Nelson, Melissa;
Bernhard, Sarah M.;
Kulko, Elizaveta;
Le Rouzic, Valerie;
Eans, Shainnel O.;
Simons, Chloe A.;
Hunkele, Amanda;
Subrath, Joan;
Ying Xian Pan;
Javitch, Jonathan A.;
McLaughlin, Jay P.

Publication type:

Article