Works about APOLIPOPROTEIN E4

Results: 1425

Cerebral hypoperfusion, brain structural integrity, and cognitive impairment in older APOE4 carriers.

Published in:

GeroScience, 2025, v. 47, n. 3, p. 4973, doi. 10.1007/s11357-025-01642-5

By:

Pappas, Ioannis;
Lohman, Trevor;
Dutt, Shubir;
Kapoor, Arunima;
Engstrom, Allison C.;
Alitin, John Paul M.;
Barnes, Samuel;
Chakhoyan, Ararat;
Saca, Lucas;
Gaggar, Raghav;
Nourollahimoghadam, Elnaz;
Wang, Danny J. J.;
Lai, Mark H. C.;
Joe, Elizabeth B.;
Ringman, John M.;
Yassine, Hussein N.;
Schneider, Lon S.;
Chui, Helena C.;
Toga, Arthur W.;
Zlokovic, Berislav V.

Publication type:

Article

Large-scale genome-wide interaction analyses on multiple cardiometabolic risk factors to identify age-specific genetic risk factors.

Published in:

GeroScience, 2025, v. 47, n. 3, p. 3597, doi. 10.1007/s11357-024-01348-0

By:

Ao, Linjun;
van Heemst, Diana;
Luo, Jiao;
Teder-Laving, Maris;
Mägi, Reedik;
Frikke-Schmidt, Ruth;
Willems van Dijk, Ko;
Noordam, Raymond

Publication type:

Article

Volume and Permeability of White Matter Hyperintensity on Cognition: A DCE Imaging Study of an Older Cohort With and Without Cognitive Impairment.

Published in:

Journal of Magnetic Resonance Imaging, 2025, v. 61, n. 5, p. 2260, doi. 10.1002/jmri.29631

By:

Lim, Changmok;
Lee, Hunwoo;
Moon, Yeonsil;
Han, Seol‐Heui;
Kim, Hee Jin;
Chung, Hyun Woo;
Moon, Won‐Jin

Publication type:

Article

APOE4 triggers dysregulated synaptic vesicle release by disrupting SNARE complex assembly.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05787-6

By:

Chen, Feng;
Chen, Yanting;
Feng, Sifan;
Chen, Huiyi;
Deng, Liehua;
Ma, Fubin;
Ke, Qiongwei;
Liang, Qiuhao;
Chen, Ji;
Peng, Xiaoping;
Lu, Jiongtong;
Liu, Yingxuan;
Xie, Yuying;
Cao, Hao;
Sun, Yuanhong;
Wu, Wenxian;
Cui, Lili;
Wang, Yan

Publication type:

Article

Pesticides and the Microbiome-Gut-Brain Axis: Convergent Pathways in the Pathogenesis of Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2023, v. 13, n. 7, p. 1079, doi. 10.3233/JPD-230206

By:

Kulcsarova, Kristina;
Bang, Corinna;
Berg, Daniela;
Schaeffer, Eva

Publication type:

Article

Appropriateness of Applying Cerebrospinal Fluid Biomarker Cutoffs from Alzheimer's Disease to Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 4, p. 1155, doi. 10.3233/JPD-212989

By:

Weinshel, Sarah;
Irwin, David J.;
Zhang, Panpan;
Weintraub, Daniel;
Shaw, Leslie M.;
Siderowf, Andrew;
Xie, Sharon X.

Publication type:

Article

Ethnic Variation in the Manifestation of Parkinson's Disease: A Narrative Review.

Published in:

Journal of Parkinson's Disease, 2020, v. 10, n. 1, p. 31, doi. 10.3233/JPD-191763

By:

Ben-Joseph, Aaron;
Marshall, Charles R.;
Lees, Andrew J.;
Noyce, Alastair J.

Publication type:

Article

Positive association of Apolipoprotein E4 polymorphism with recurrent pregnancy loss in Iranian patients.

Published in:

Journal of Assisted Reproduction & Genetics, 2013, v. 30, n. 2, p. 265, doi. 10.1007/s10815-012-9897-5

By:

Asgari, Nooshin;
Akbari, Mohammad;
Zare, Shohre;
Babamohammadi, Gholamreza

Publication type:

Article

The entrancing role of dietary polyphenols against the most frequent aging‐associated diseases.

Published in:

Medicinal Research Reviews, 2024, v. 44, n. 1, p. 235, doi. 10.1002/med.21985

By:

Shah, Muhammad Ajmal;
Faheem, Hafiza Ishmal;
Hamid, Ayesha;
Yousaf, Rimsha;
Haris, Muhammad;
Saleem, Uzma;
Shah, Ghulam Mujtaba;
Alhasani, Reem H.;
Althobaiti, Norah A.;
Alsharif, Ifat;
Silva, Ana Sanches

Publication type:

Article

Antiplatelet drugs: Potential therapeutic options for the management of neurodegenerative diseases.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 6, p. 1835, doi. 10.1002/med.21965

By:

Beura, Samir K.;
Dhapola, Rishika;
Panigrahi, Abhishek R.;
Yadav, Pooja;
Kumar, Reetesh;
Reddy, Dibbanti H.;
Singh, Sunil K.

Publication type:

Article

In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis.

Published in:

Hippocampus, 2023, v. 33, n. 4, p. 322, doi. 10.1002/hipo.23502

By:

Lee, Hyunah;
Price, Jack;
Srivastava, Deepak P.;
Thuret, Sandrine

Publication type:

Article

APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults.

Published in:

Hippocampus, 2021, v. 31, n. 8, p. 845, doi. 10.1002/hipo.23327

By:

Memel, Molly;
Staffaroni, Adam M.;
Cobigo, Yann;
Casaletto, Kaitlin B.;
Fonseca, Corrina;
Bettcher, Brianne M.;
Yassa, Michael A.;
Elahi, Fanny M.;
Wolf, Amy;
Rosen, Howard J.;
Kramer, Joel H.

Publication type:

Article

Genetics of Atopic Dermatitis: From DNA Sequence to Clinical Relevance.

Published in:

2019

By:

Løset, Mari;
Brown, Sara J.;
Saunes, Marit;
Hveem, Kristian;
Brown, Sara J

Publication type:

journal article

US Dementia Cases to Double by 2060: Daily Dose.

Published in:

Patient Care (Online), 2025, p. 4

By:

Jennings, Sydney

Publication type:

Article

Investigational Oral Agent Muvalaplin Reduces Lp(a) by Up to 85% in High-Risk Adults: Phase 2 Data.

Published in:

Patient Care (Online), 2024, p. 1

By:

Caffrey, Mary

Publication type:

Article

Adjusted Donanemab Dosing Lowers ARIA-E Risk in Early Alzheimer Disease: Daily Dose.

Published in:

Patient Care (Online), 2024, p. 2

By:

Jennings, Sydney

Publication type:

Article

Apolipoproteins and Its Association with Dengue Virus Serotype 2 (DENV-2) Infectivity in Human Hepatoma Cell Line (Huh7).

Published in:

Trends in Sciences, 2024, v. 21, n. 7, p. 1, doi. 10.48048/tis.2024.7674

By:

Ahmad, Radzi Ikhsan;
Nor, Fadzilah Mohd;
Seok Mui Wang;
Ismail, Aletza Mohd.;
Noor, Julina@Azimah Md;
Hoh Boon Peng;
Abdul Rahman, Thuhairah Hasrah

Publication type:

Article

APOE4, oxidative stress and decreased repair capacity - a no-brainer. Faulty lipid metabolism and increased levels of oxidative damage may be risk factors in the pathogenesis of late-onset dementia.

Published in:

BioDiscovery, 2017, p. 1, doi. 10.7750/BioDiscovery.2015.17.1

By:

Nayyar, Ashima;
Chakalova, Lubomira

Publication type:

Article

Machine Learning-Driven Prediction of Brain Age for Alzheimer's Risk: APOE4 Genotype and Gender Effects.

Published in:

Bioengineering (Basel), 2024, v. 11, n. 9, p. 943, doi. 10.3390/bioengineering11090943

By:

Woods, Carter;
Xing, Xin;
Khanal, Subash;
Lin, Ai-Ling

Publication type:

Article

Apolipoprotein B/Apolipoprotein A-I Ratio Is a Better Predictor of Cancer Mortality Compared with C-Reactive Protein: Results from Two Multi-Ethnic US Populations.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 170, doi. 10.3390/jcm9010170

By:

Mazidi, Mohsen;
Katsiki, Niki;
Mikhailidis, Dimitri P.;
Radenkovic, Dina;
Pella, Daniel;
Banach, Maciej

Publication type:

Article

The Role of Irisin in Alzheimer's Disease.

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 11, p. 407, doi. 10.3390/jcm7110407

By:

Kim, Oh Yoen;
Song, Juhyun

Publication type:

Article

Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 135, n. 3, p. 237, doi. 10.1111/bcpt.14055

By:

Poblano, Joan;
Castillo‐Tobías, Ileana;
Berlanga, Lia;
Tamayo‐Ordoñez, María Concepción;
del Carmen Rodríguez‐Salazar, María;
Silva‐Belmares, Sonia Yesenia;
Aguayo‐Morales, Hilda;
Cobos‐Puc, Luis E.

Publication type:

Article

Non-Genetic Risk Factors for Dementia and Alzheimer’s Disease.

Published in:

Jordan Medical Journal, 2023, v. 57, n. 3, p. 206, doi. 10.35516/jmj.v57i3.1673

By:

Bazzari, Firas H.;
Bazzari, Amjad H.

Publication type:

Article

APOE genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia.

Published in:

Annals of Clinical & Translational Neurology, 2025, v. 12, n. 2, p. 366, doi. 10.1002/acn3.52250

By:

Philippi, Sarah M.;
BP, Kailash;
Raj, Towfique;
Castellano, Joseph M.

Publication type:

Article

Distinct cerebral small vessel disease impairment in early‐ and late‐onset Alzheimer's disease.

Published in:

Annals of Clinical & Translational Neurology, 2023, v. 10, n. 8, p. 1326, doi. 10.1002/acn3.51824

By:

Luo, Xiao;
Hong, Hui;
Li, Kaicheng;
Zeng, Qingze;
Wang, Shuyue;
Li, Zheyu;
Fu, Yanv;
Liu, Xiaocao;
Hong, Luwei;
Li, Jixuan;
Zhang, Xinyi;
Zhong, Siyan;
Jiaerken, Yeerfan;
Liu, Zhirong;
Chen, Yanxing;
Huang, Peiyu;
Zhang, Minming

Publication type:

Article

Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease.

Published in:

Annals of Clinical & Translational Neurology, 2023, v. 10, n. 5, p. 744, doi. 10.1002/acn3.51757

By:

Qiao, Min;
Lee, Annie J.;
Reyes‐Dumeyer, Dolly;
Tosto, Giuseppe;
Faber, Kelley;
Goate, Alison;
Renton, Alan;
Chao, Michael;
Boeve, Brad;
Cruchaga, Carlos;
Pericak‐Vance, Margaret;
Haines, Jonathan L.;
Rosenberg, Roger;
Tsuang, Debby;
Sweet, Robert A.;
Bennett, David A.;
Wilson, Robert S.;
Foroud, Tatiana;
Mayeux, Richard;
Vardarajan, Badri N.

Publication type:

Article

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset.

Published in:

Annals of Clinical & Translational Neurology, 2022, v. 9, n. 12, p. 1962, doi. 10.1002/acn3.51689

By:

Tort‐Merino, Adrià;
Falgàs, Neus;
Allen, Isabel E.;
Balasa, Mircea;
Olives, Jaume;
Contador, José;
Castellví, Magdalena;
Juncà‐Parella, Jordi;
Guillén, Núria;
Borrego‐Écija, Sergi;
Bosch, Bea;
Fernández‐Villullas, Guadalupe;
Ramos‐Campoy, Oscar;
Antonell, Anna;
Rami, Lorena;
Sánchez‐Valle, Raquel;
Lladó, Albert

Publication type:

Article

CYLD variants identified in Alzheimer's disease and frontotemporal dementia patients.

Published in:

Annals of Clinical & Translational Neurology, 2022, v. 9, n. 10, p. 1596, doi. 10.1002/acn3.51655

By:

Xiao, Xuewen;
Xu, Tianyan;
Liu, Hui;
Liu, Xixi;
Liao, Xinxin;
Zhou, Yafang;
Zhou, Lu;
Wang, Xin;
Zhu, Yuan;
Yang, Qijie;
Hao, Xiaoli;
Liu, Yingzi;
Jiang, Hong;
Guo, Jifeng;
Wang, Junling;
Tang, Beisha;
Li, Jinchen;
Shen, Lu;
Jiao, Bin

Publication type:

Article

Elevated matrix metalloproteinase‐9 levels in neuronal extracellular vesicles in Alzheimer's disease.

Published in:

Annals of Clinical & Translational Neurology, 2020, v. 7, n. 9, p. 1681, doi. 10.1002/acn3.51155

By:

Gu, Dongmei;
Liu, Fang;
Meng, Meng;
Zhang, Liling;
Gordon, Marc L.;
Wang, Ying;
Cai, Li;
Zhang, Nan

Publication type:

Article

Hippocampal sclerosis, TDP‐43, and the duration of the symptoms of dementia of AD patients.

Published in:

Annals of Clinical & Translational Neurology, 2020, v. 7, n. 9, p. 1546, doi. 10.1002/acn3.51135

By:

Lopez, Oscar L.;
Kofler, Julia;
Chang, YueFang;
Berman, Sarah B.;
Becker, James T.;
Sweet, Robert A.;
Nadkarni, Neelesh;
Patira, Riddhi;
Kamboh, M. Ilyas;
Cohen, Ann D.;
Snitz, Beth E.;
Kuller, Lewis H.;
Klunk, William E.

Publication type:

Article

High‐resolution metabolomic profiling of Alzheimer's disease in plasma.

Published in:

Annals of Clinical & Translational Neurology, 2020, v. 7, n. 1, p. 36, doi. 10.1002/acn3.50956

By:

Niedzwiecki, Megan M.;
Walker, Douglas I.;
Howell, Jennifer Christina;
Watts, Kelly D.;
Jones, Dean P.;
Miller, Gary W.;
Hu, William T.

Publication type:

Article

Polygenic risk and hazard scores for Alzheimer's disease prediction.

Published in:

Annals of Clinical & Translational Neurology, 2019, v. 6, n. 3, p. 456, doi. 10.1002/acn3.716

By:

Leonenko, Ganna;
Sims, Rebecca;
Shoai, Maryam;
Frizzati, Aura;
Bossù, Paola;
Spalletta, Gianfranco;
Fox, Nick C.;
Williams, Julie;
Hardy, John;
Escott‐Price, Valentina

Publication type:

Article

Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease.

Published in:

Annals of Clinical & Translational Neurology, 2016, v. 3, n. 12, p. 934, doi. 10.1002/acn3.339

By:

Bischof, Gérard N.;
Jessen, Frank;
Fliessbach, Klaus;
Dronse, Julian;
Hammes, Jochen;
Neumaier, Bernd;
Onur, Oezguer;
Fink, Gereon R.;
Kukolja, Juraj;
Drzezga, Alexander;
Eimeren, Thilo

Publication type:

Article

Apolipoproteins A and B and PCSK9: Nontraditional Cardiovascular Risk Factors in Chronic Kidney Disease and in End-Stage Renal Disease.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/6906278

By:

Vlad, Cristiana-Elena;
Foia, Liliana;
Popescu, Roxana;
Ivanov, Iuliu;
Luca, Mihaela Catalina;
Delianu, Carmen;
Toma, Vasilica;
Statescu, Cristian;
Rezus, Ciprian;
Florea, Laura

Publication type:

Article

Expanding the phenotype of TARDBP mutation in a Tunisian family with clinical phenotype heterogeneity.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2022, v. 23, n. 7/8, p. 623, doi. 10.1080/21678421.2022.2089856

By:

Kacem, Imen;
Sghaier, Ikram;
Ticozzi, Nicola;
Mrabet, Saloua;
Paverelli, Silvia;
Nasri, Amina;
Ratti, Antonia;
Ben Djebara, Mouna;
Gargouri-Berrachid, Amina;
Silani, Vincenzo;
Gouider, Riadh

Publication type:

Article

Effect of Adding Apolipoprotein B Testing on the Prevalence of Dyslipidemia and Risk of Cardiovascular Disease in the Korean Adult Population.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 3, p. 169, doi. 10.3390/metabo14030169

By:

Choi, Rihwa;
Lee, Sang Gon;
Lee, Eun Hee

Publication type:

Article

Effects of APOE Genotype and Western Diet on Metabolic Phenotypes in Female Mice.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 2, p. 287, doi. 10.3390/metabo13020287

By:

Christensen, Amy;
Pike, Christian J.

Publication type:

Article

The Roles of Fatty Acids and Apolipoproteins in the Kidneys.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 5, p. 462, doi. 10.3390/metabo12050462

By:

Pan, Xiaoyue

Publication type:

Article

Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 10, p. 690, doi. 10.3390/metabo11100690

By:

Behbodikhah, Jennifer;
Ahmed, Saba;
Elyasi, Ailin;
Kasselman, Lora J.;
De Leon, Joshua;
Glass, Amy D.;
Reiss, Allison B.

Publication type:

Article

Effects of different kinds of anti-Alzheimer's disease drugs on cognitive improvement: protocol for a systematic review and network meta-analysis of phase III clinical trials.

Published in:

Systematic Reviews, 2022, v. 11, n. 1, p. 1, doi. 10.1186/s13643-022-01964-x

By:

Lyu, Diyang;
Gong, Min;
Zhang, Yong;
Lyu, Xuanxin

Publication type:

Article

Évolution des séquelles cognitivo-comportementales d'un traumatisme cranio-cérébral modéré à sévère plusieurs années après sa survenue. Synthèse et perspectives: Age and long-term cognitive-behavioral disorders related to moderate and severe traumatic brain injury: a review

Published in:

Gériatrie et Psychologie Neuropsychiatrie du Vieillissement, 2022, v. 20, n. 1, p. 96, doi. 10.1684/pnv.2022.1014

By:

Holin, Samantha;
Allart, Étienne;
Delecroix, Hélène;
Kozlowski, Odile;
Moroni, Christine

Publication type:

Article

Yizhi Qingxin Formula Extract Ameliorates Cognitive Decline in Aged Rats via the Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Pathway.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00510

By:

Ma, Lina;
Cao, Yu;
Wang, Feixue;
Li, Zehui;
Wang, Zhiyong;
Yang, Yang;
Pei, Hui;
Li, Hao

Publication type:

Article

Metabolites of intestinal fora can be used as diagnostic and progressive markers for mild cognitive impairment.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 01, doi. 10.3389/fcimb.2024.1351523

By:

Liquan Lu;
Lei Qin;
Xiaohui Zhao;
Zanhua Liu;
Xiaoting Qiu;
Shuo Yang;
Haihan Song;
Juan Yang

Publication type:

Article

Relationship between the monoamine oxidase gene overactivity and the other pathophysiological and behavioral parameters implicated in memory deficiency in albino Winstar rats as Alzheimer's disease model.

Published in:

Journal of Applied & Natural Science, 2021, v. 13, n. 4, p. 1274, doi. 10.31018/jans.v13i4.3024

By:

Chabuk, Halla Abdul-Hadi;
Jameel, Zahraa Isam

Publication type:

Article

DIFFERENCE IN APOLIPOPROTEIN E GENOTYPE DISTRIBUTION BETWEEN DENTATE AND EDENTULOUS ELDERLY PATIENTS WITH ALZHEIMER DISEASE.

Published in:

Genetika (0534-0012), 2016, v. 48, n. 2, p. 699, doi. 10.2298/GENSR1602699P

By:

POPOVAC, Aleksandra;
STANČIĆ, Ivica;
DESPOTOVIĆ, Nebojša;
NIKOLIĆ, Nađa;
STEFANOVA, Elka;
MILAŠIN, Jelena

Publication type:

Article

Assessing the impact of novel risk loci on Alzheimer's and Parkinson's diseases in a Chinese Han cohort.

Published in:

Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2024.1326692

By:

Huimin Yan;
Minglei Liu;
Yuan Gao;
Yanpeng Yuan;
Xiaojing Liu;
Yangyang Wang;
Lanjun Li;
Qingzhi Wang;
Yanlin Wang;
Changhe Shi;
Yuming Xu;
Jing Yang

Publication type:

Article

Alzheimer’s disease: the role of extrinsic factors in its development, an investigation of the environmental enigma.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1303111

By:

Suresh, Swathi;
S., Ankul Singh;
Rushendran, Rapuru;
Vellapandian, Chitra;
Prajapati, Bhupendra

Publication type:

Article

Predictive factors for Alzheimer's disease progression: a comprehensive retrospective analysis of 3,553 cases with 211 months follow-up.

Published in:

Frontiers in Neurology, 2023, p. 01, doi. 10.3389/fneur.2023.1239995

By:

Özge, Aynur;
Ghouri, Reza;
Öksüz, Nevra;
Taşdelen, Bahar

Publication type:

Article

Exploring the relationship between patient-relevant outcomes and Alzheimer's disease progression assessed using the clinical dementia rating scale: a systematic literature review.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1208802

By:

Cummings, Jeffrey;
Hahn-Pedersen, Julie Hviid;
Eichinger, Christian Stefan;
Freeman, Caroline;
Clark, Alice;
Tarazona, Luis Rafael Solís;
Lanctôt, Krista

Publication type:

Article

Alzheimer's disease: a mini-review for the clinician.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1178588

By:

Madnani, Rishi S.

Publication type:

Article