Works matching DE "ANTISENSE drugs"

Results: 38

Viral therapeutics: Antisense therapy makes sense for HCV.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 5, p. 301, doi. 10.1038/nrmicro3022

By:

Kåhrström, Christina Tobin

Publication type:

Article

Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides.

Published in:

Angewandte Chemie, 2014, v. 126, n. 38, p. 10278, doi. 10.1002/ange.201405355

By:

Yamazoe, Sayumi;
Liu, Qingyang;
McQuade, Lindsey E.;
Deiters, Alexander;
Chen, James K.

Publication type:

Article

CLIFinder: identification of LINE-1 chimeric transcripts in RNA-seq data.

Published in:

Bioinformatics, 2018, v. 34, n. 4, p. 688, doi. 10.1093/bioinformatics/btx671

By:

Pinson, Marie-Elisa;
Pogorelcnik, Romain;
Court, Franck;
Arnaud, Philippe;
Vaurs-Barrière, Catherine

Publication type:

Article

Expression of Amiloride-sensitive Epithelial Sodium Channels in Mouse Taste Cells after Chorda Tympani Nerve Crush.

Published in:

Chemical Senses, 2005, v. 30, n. 6, p. 531, doi. 10.1093/chemse/bji046

By:

Shigemura, Noriatsu;
Islam, Abu Ahammad S.;
Sadamitsu, Chiharu;
Yoshida, Ryusuke;
Yasumatsu, Keiko;
Ninomiya, Yuzo

Publication type:

Article

Biotech comes to its 'antisenses' after hard-won drug approval.

Published in:

Nature Medicine, 2013, v. 19, n. 3, p. 252, doi. 10.1038/nm0313-252

By:

Jiang, Kevin

Publication type:

Article

Hopes soar as cholesterol plummets with new drug class.

Published in:

Nature Medicine, 2012, v. 18, n. 5, p. 633, doi. 10.1038/nm0512-633

By:

Holmes, David

Publication type:

Article

Molecular imaging and pharmacokinetics of <sup>99m</sup>Tc-hTERT antisense oligonucleotide as a potential tumor imaging probe.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2014, v. 57, n. 2, p. 97, doi. 10.1002/jlcr.3171

By:

Liu, Meng;
Wang, Rong Fu;
Yan, Ping;
Zhang, Chun Li;
Cui, Yong Gang

Publication type:

Article

Antisense-based therapy for the treatment of spinal muscular atrophy.

Published in:

Journal of Cell Biology, 2012, v. 199, n. 1, p. 21, doi. 10.1083/jcb.201207087

By:

Rigo, Frank;
Yimin Hua;
Krainer, Adrian R.;
Bennett, C. Frank

Publication type:

Article

Modified Oligonucleotides: Strides towards Antisense Drugs.

Published in:

Trends in Carbohydrate Research, 2013, v. 5, n. 3, p. 1

By:

Sharma, Vivek K.;
Kumar, Rajesh;
Rungta, Pallavi;
Parmar, Virinder S.;
Prasad, Ashok K.

Publication type:

Article

Impact of patient characteristics on the clinical efficacy of mongersen (GED-0301), an oral Smad7 antisense oligonucleotide, in active Crohn's disease.

Published in:

Alimentary Pharmacology & Therapeutics, 2016, v. 43, n. 6, p. 717, doi. 10.1111/apt.13526

By:

Monteleone, G.;
Di Sabatino, A.;
Ardizzone, S.;
Pallone, F.;
Usiskin, K.;
Zhan, X.;
Rossiter, G.;
Neurath, M. F.

Publication type:

Article

Cure Hunter to Treat Marfan Syndrome; Introducing New Remedies to Target Transforming Growth Factor- Beta (TGF-β).

Published in:

Journal of Pakistan Medical Students, 2013, v. 3, n. 1, p. 28

By:

Hoseini, Sayed Shahabuddin;
Shoar, Saeed;
Dehpour, Ahmadreza;
Naderan, Mohammad;
Shoar, Nasrin

Publication type:

Article

In Silico Screening Based on Predictive Algorithms as a Design Tool for Exon Skipping Oligonucleotides in Duchenne Muscular Dystrophy.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120058

By:

Echigoya, Yusuke;
Mouly, Vincent;
Garcia, Luis;
Yokota, Toshifumi;
Duddy, William

Publication type:

Article

Targeting Eukaryotic Translation in Mesothelioma Cells with an eIF4E-Specific Antisense Oligonucleotide.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081669

By:

Jacobson, Blake A.;
Thumma, Saritha C.;
Jay-Dixon, Joseph;
Patel, Manish R.;
Dubear Kroening, K.;
Kratzke, Marian G.;
Etchison, Ryan G.;
Konicek, Bruce W.;
Graff, Jeremy R.;
Kratzke, Robert A.

Publication type:

Article

Preparation of 5′-O-(1-Thiotriphosphate)-Modified Oligonucleotides Using Polymerase-Endonuclease Amplification Reaction (PEAR).

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0067558

By:

Li, Biao;
Dong, Shihua;
Wu, Jiajun;
Zhang, Jianye;
Chen, Gang;
Dong, Quanjiang;
Zhu, Xinhong;
Wang, Xiaolong

Publication type:

Article

A phase 1 open-label trial shows that smad7 antisense oligonucleotide (GED0301) does not increase the risk of small bowel strictures in Crohn's disease.

Published in:

Alimentary Pharmacology & Therapeutics, 2012, v. 36, n. 9, p. 850, doi. 10.1111/apt.12051

By:

Zorzi, F.;
Calabrese, E.;
Monteleone, I.;
Fantini, M.;
Onali, S.;
Biancone, L.;
Pallone, F.;
Monteleone, G.

Publication type:

Article

Amygdaloid zif268 participated in the D-cycloserine facilitation effect on the extinction of conditioned fear.

Published in:

Psychopharmacology, 2015, v. 232, n. 20, p. 3809, doi. 10.1007/s00213-015-4042-7

By:

Wu, I-Tek;
Tang, Tso-Hao;
Ko, Meng-Chang;
Chiu, Chen-Yu;
Lu, Kwok-Tung

Publication type:

Article

Regulatory watch: Antisense approval provides boost to the field.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 3, p. 179, doi. 10.1038/nrd3963

By:

Tse, Man Tsuey

Publication type:

Article

Efficacy of antisense monocyte chemoattractant protein-1 (MCP-1) in a rat model of mesangial proliferative glomerulonephritis.

Published in:

Renal Failure, 2013, v. 35, n. 10, p. 1418, doi. 10.3109/0886022X.2013.828309

By:

Liu, Hua;
Zhang, Xin-Ping;
Yi, Zhu-Wen

Publication type:

Article

Antagonism of miRNA in heart failure: first evidence in human.

Published in:

European Heart Journal, 2021, v. 42, n. 2, p. 189, doi. 10.1093/eurheartj/ehaa967

By:

Baker, Andrew H.;
Giacca, Mauro

Publication type:

Article

Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study.

Published in:

European Heart Journal, 2021, v. 42, n. 2, p. 178, doi. 10.1093/eurheartj/ehaa898

By:

Täubel, Jörg;
Hauke, Wilfried;
Rump, Steffen;
Viereck, Janika;
Batkai, Sandor;
Poetzsch, Jenny;
Rode, Laura;
Weigt, Henning;
Genschel, Celina;
Lorch, Ulrike;
Theek, Carmen;
Levin, Arthur A.;
Bauersachs, Johann;
Solomon, Scott D.;
Thum, Thomas

Publication type:

Article

Synthesis of Methoxyethyl Nucleoside Dimer Phosphoramidites.

Published in:

Bulletin of the Korean Chemical Society, 2016, v. 37, n. 5, p. 667, doi. 10.1002/bkcs.10749

By:

Yu, Gi Weon;
Kang, Yong Han

Publication type:

Article

Intravitreal treatment with antisense oligonucleotides targeting tumor necrosis factor-α in murine herpes simplex virus type 1 retinitis.

Published in:

Graefe's Archive of Clinical & Experimental Ophthalmology, 2012, v. 250, n. 2, p. 231, doi. 10.1007/s00417-011-1840-4

By:

Grajewski, Rafael;
Li, Jin;
Wasmuth, Susanne;
Hennig, Maren;
Bauer, Dirk;
Heiligenhaus, Arnd

Publication type:

Article

MiR-377 Mediates the Effect of Syk on Atherosclerosis in ApoE-/- Mice.

Published in:

Journal of Hainan Medical University, 2020, v. 26, n. 2, p. 17

By:

Guo-Hua Chen;
Xiao-Xiao Wang;
Jian Feng;
Yan Wu;
Lei Li

Publication type:

Article

In vivo uptake of antisense oligonucleotide drugs predicted by ab initio quantum mechanical calculations.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-85453-6

By:

Hansen, Henrik Frydenlund;
Albaek, Nanna;
Hansen, Bo Rode;
Shim, Irene;
Bohr, Henrik;
Koch, Troels

Publication type:

Article

Antisense oligonucleotide to treat a rare hereditary disease.

Published in:

Medical Writing, 2018, v. 27, n. 3, p. 49

By:

Alahari, Anuradha

Publication type:

Article

Functional correction by antisense therapy of a splicing mutation in the GALT gene.

Published in:

European Journal of Human Genetics, 2015, v. 23, n. 4, p. 500, doi. 10.1038/ejhg.2014.149

By:

Coelho, Ana I;
Lourenço, Sílvia;
Trabuco, Matilde;
Silva, Maria João;
Oliveira, Anabela;
Gaspar, Ana;
Diogo, Luísa;
Tavares de Almeida, Isabel;
Vicente, João B;
Rivera, Isabel

Publication type:

Article

In vitro antisense therapeutics for a deep intronic mutation causing Neurofibromatosis type 2.

Published in:

European Journal of Human Genetics, 2013, v. 21, n. 7, p. 769, doi. 10.1038/ejhg.2012.261

By:

Castellanos, Elisabeth;
Rosas, Imma;
Solanes, Ares;
Bielsa, Isabel;
Lázaro, Conxi;
Carrato, Cristina;
Hostalot, Cristina;
Prades, Pepe;
Roca-Ribas, Francesc;
Blanco, Ignacio;
Serra, Eduard

Publication type:

Article

Long-term Restoration of Cardiac Dystrophin Expression in Golden Retriever Muscular Dystrophy Following rAAV6-mediated Exon Skipping.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 580, doi. 10.1038/mt.2011.264

By:

Bish, Lawrence T;
Sleeper, Meg M;
Forbes, Sean C;
Wang, Bingjing;
Reynolds, Caryn;
Singletary, Gretchen E;
Trafny, Dennis;
Morine, Kevin J;
Sanmiguel, Julio;
Cecchini, Sylvain;
Virag, Tamas;
Vulin, Adeline;
Beley, Cyriaque;
Bogan, Janet;
Wilson, James M;
Vandenborne, Krista;
Kornegay, Joe N;
Walter, Glenn A;
Kotin, Robert M;
Garcia, Luis

Publication type:

Article

A population pharmacokinetic meta-analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2017, v. 83, n. 9, p. 1932, doi. 10.1111/bcp.13287

By:

Edwards, Alena Y.;
Elgart, Anna;
Farrell, Colm;
Barnett-Griness, Ofra;
Rabinovich-Guilatt, Laura;
Spiegelstein, Ofer

Publication type:

Article

Clinical pharmacological properties of mipomersen ( Kynamro), a second generation antisense inhibitor of apolipoprotein B.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 76, n. 2, p. 269, doi. 10.1111/j.1365-2125.2012.04469.x

By:

Crooke, Stanley T.;
Geary, Richard S.

Publication type:

Article

Antisense Therapy in Neurology.

Published in:

Journal of Personalized Medicine, 2013, v. 3, n. 3, p. 144, doi. 10.3390/jpm3030144

By:

Lee, Joshua J. A.;
Toshifumi Yokota

Publication type:

Article

FXI-ASO May Represent a New Class of Antithrombotic Agents.

Published in:

MD Conference Express, 2014, v. 14, n. 55, p. 10, doi. 10.1177/1559897714568644

By:

Lederman, Lynne

Publication type:

Article

Intravesical Liposome and Antisense Treatment for Detrusor Overactivity and Interstitial Cystitis/Painful Bladder Syndrome.

Published in:

ISRN Otolaryngology, 2014, p. 1, doi. 10.1155/2014/601653

By:

Pradeep Tyagi;
Kashyap, Mahendra P.;
Naoki Kawamorita;
Tsuyoshi Yoshizawa;
Chancellor, Michael;
Naoki Yoshimura

Publication type:

Article

Knocking down the transcript of NF-kappaB modulates the reciprocal regulation of endogenous antioxidants and feeding behavior in phenylpropanolamine-treated rats.

Published in:

Archives of Toxicology, 2012, v. 86, n. 3, p. 453, doi. 10.1007/s00204-011-0761-7

By:

Kuo, Dong-Yih;
Chen, Pei-Ni;
Chu, Shu-Chen;
Hsieh, Yih-Shou

Publication type:

Article

Silencing human genetic diseases with oligonucleotide-based therapies.

Published in:

Human Genetics, 2013, v. 132, n. 5, p. 481, doi. 10.1007/s00439-013-1288-1

By:

Martínez, Tamara;
Wright, Natalia;
López-Fraga, Marta;
Jiménez, Ana;
Pañeda, Covadonga

Publication type:

Article

Celgene shells out for antisense drug.

Published in:

Nature Biotechnology, 2014, v. 32, n. 7, p. 605, doi. 10.1038/nbt0714-605b

By:

Ratner, Mark

Publication type:

Article

Antisense battles small molecule for slice of rare lipid disorder market.

Published in:

Nature Biotechnology, 2013, v. 31, n. 3, p. 179, doi. 10.1038/nbt0313-179

By:

Sinha, Gunjan

Publication type:

Article

Isis inks two antisense deals.

Published in:

Nature Biotechnology, 2013, v. 31, n. 2, p. 91, doi. 10.1038/nbt0213-91a

By:

Allison, Malorye

Publication type:

Article