Works matching DE "ANTINEOPLASTIC agent development"

Results: 101

Total Synthesis of the Antimitotic Marine Macrolide (−)-Leiodermatolide.

Published in:

Angewandte Chemie, 2014, v. 126, n. 10, p. 2730, doi. 10.1002/ange.201310164

By:

Paterson, Ian;
Ng, Kenneth K. ‐ H.;
Williams, Simon;
Millican, David C.;
Dalby, Stephen M.

Publication type:

Article

Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents.

Published in:

BioMetals, 2009, v. 22, n. 1, p. 61, doi. 10.1007/s10534-008-9185-0

By:

Marvin Miller;
Helen Zhu;
Yanping Xu;
Chunrui Wu;
Andrew Walz;
Anne Vergne;
John Roosenberg;
Garrett Moraski;
Albert Minnick;
Julia McKee-Dolence;
Jingdan Hu;
Kelley Fennell;
E. Kurt Dolence;
Li Dong;
Scott Franzblau;
Francois Malouin;
Ute Möllmann

Publication type:

Article

Induction of apoptosis in human cervical carcinoma HeLa cells by active compounds from Hypericum ascyron L.

Published in:

Oncology Letters, 2018, v. 15, n. 3, p. 3944, doi. 10.3892/ol.2018.7812

By:

Li, Xiu-Mei;
Luo, Xue-Gang;
He, Jun-Fang;
Wang, Nan;
Zhou, Hao;
Yang, Pei-Long;
Zhang, Tong-Cun

Publication type:

Article

Investigation into metastatic processes and the therapeutic effects of gemcitabine on human pancreatic cancer using an orthotopic SUIT‑2 pancreatic cancer mouse model.

Published in:

Oncology Letters, 2018, v. 15, n. 3, p. 3091, doi. 10.3892/ol.2017.7722

By:

Higuchi, Tamami;
Yokobori, Takehiko;
Naito, Tomoharu;
Kakinuma, Chihaya;
Hagiwara, Shinji;
Nishiyama, Masahiko;
Asao, Takayuki

Publication type:

Article

Models for the Prediction of Receptor Tyrosine Kinase Inhibitory Activity of Substituted 3-Aminoindazole Analogues.

Published in:

Scientia Pharmaceutica, 2011, v. 79, n. 2, p. 239, doi. 10.3797/scipharm.1102-08

By:

Gupta, Monika;
Dureja, Harish;
Madan, Anil Kumar

Publication type:

Article

Biosimilars in Oncology.

Published in:

Cancer & Chemotherapy Reviews, 2015, v. 10, n. 2, p. 43

By:

Longo, Federico;
Carrato, Alfredo

Publication type:

Article

The search for child cancer drugs grows up.

Published in:

Nature Medicine, 2011, v. 17, n. 3, p. 267, doi. 10.1038/nm0311-267

By:

Morgan, Branwen

Publication type:

Article

T cell receptors and cancer: gain gives pain.

Published in:

Nature Medicine, 2010, v. 16, n. 5, p. 520, doi. 10.1038/nm0510-520

By:

Brenner, Malcolm

Publication type:

Article

Pharmacokinetic properties and antitumor efficacyof the 5-fluorouracil loaded PEG-hydrogel.

Published in:

BMC Cancer, 2010, v. 10, p. 211, doi. 10.1186/1471-2407-10-211

By:

Hee Yi;
Hee-Jung Cho;
Soo-Min Cho;
Dong-Goo Lee;
El-Aty, A. M. Abd;
So-Jeong Yoon;
Gun-Won Bae;
Kwang Nho;
Bokyung Kim;
Chi-Ho Lee;
Jin-Suk Kim;
Bartlett, Michael G.;
Ho-Chul Shin

Publication type:

Article

Association of nutritional status and serumalbumin levels with development of toxicity inpatients with advanced non-small cell lungcancer treated with paclitaxel-cisplatinchemotherapy: a prospective study.

Published in:

BMC Cancer, 2010, v. 10, p. 50, doi. 10.1186/1471-2407-10-50

By:

Arrieta, Oscar;
Michel Ortega, Rosa M.;
Villanueva-Rodríguez, Geraldine;
Serna-Thomé, Maria G.;
Flores-Estrada, Diana;
Diaz-Romero, Consuelo;
Rodríguez, Cindy M.;
Martínez, Luis;
Sánchez-Lara, Karla

Publication type:

Article

Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity-state of the art.

Published in:

Supportive Care in Cancer, 2011, v. 19, p. 43, doi. 10.1007/s00520-010-1003-x

By:

Grunberg, Steven;
Warr, David;
Gralla, Richard;
Rapoport, Bernardo;
Hesketh, Paul;
Jordan, Karin;
Espersen, Birgitte

Publication type:

Article

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00252

By:

Schadt, Eric E.;
Buchanan, Sean;
Brennand, Kristen J.;
Merchant, Kalpana M.;
Auld, Douglas;
Solomon, Jonathan M.

Publication type:

Article

What is cancer chemotherapy?

Published in:

Acta Oncologica, 2001, v. 40, n. 2/3, p. 166, doi. 10.1080/02841860151116204

By:

Nygren, Peter

Publication type:

Article

Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007112

By:

Bullock, Alex N.;
Russo, Santina;
Amos, Ann;
Pagano, Nicholas;
Bregman, Howard;
Debreczeni, Judit É.;
Lee, Wen Hwa;
Delft, Frank von;
Meggers, Eric;
Knapp, Stefan

Publication type:

Article

Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer

Published in:

Otolaryngology-Head & Neck Surgery, 2004, v. 131, n. 4, p. 477, doi. 10.1016/j.otohns.2004.04.019

By:

Tran, Hao Mimi;
Shi, Guoli;
Li, Gouyan;
Carney, James P.;
O'Malley, Bert;
Li, Daqing

Publication type:

Article

The Truncated Human Telomeric Sequence forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K+ Solution.

Published in:

Chemical Biology & Drug Design, 2016, v. 88, n. 1, p. 122, doi. 10.1111/cbdd.12740

By:

Liu, Yuxia;
Cheng, Dengfeng;
Ge, Min;
Lin, Weizhen

Publication type:

Article

QSAR Models for isoindolinone-based p53-MDM2 Interaction Inhibitors Using Linear and Non-linear Statistical Methods.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 5, p. 691, doi. 10.1111/j.1747-0285.2012.01322.x

By:

Dong, Xiaowu;
Yan, Jingying;
Lu, Dong;
Wu, Peng;
Gao, Jiadi;
Liu, Tao;
Yang, Bo;
Hu, Yongzhou

Publication type:

Article

News in brief.

Published in:: Chemistry & Industry, 2008, n. 23, p. 9
Publication type:: Article

Diaphorase Coupling Protocols for Red-Shifting Dehydrogenase Assays.

Published in:

Assay & Drug Development Technologies, 2016, v. 14, n. 3, p. 207, doi. 10.1089/adt.2016.706

By:

Davis, Mindy I.;
Shen, Min;
Simeonov, Anton;
Hall, Matthew D.

Publication type:

Article

Far-red fluorescent cell line for preclinical study of HER2-targeted agents.

Published in:

Doklady Biochemistry & Biophysics, 2015, v. 465, n. 1, p. 410, doi. 10.1134/S1607672915060174

By:

Balalaeva, I.;
Sokolova, E.;
Brilkina, A.;
Deyev, S.;
Petrov, R.

Publication type:

Article

Bevacizumab: a new way of doing business?

Published in:

Eye (0950-222X), 2006, v. 20, n. 9, p. 985, doi. 10.1038/sj.eye.6702501

By:

Canning, C.;
Lotery, A.

Publication type:

Article

Antimitotic and toxicogenetic action of Stevia urticifolia aerial parts on proliferating vegetal and mammalian cells: in vitro and in vivo traditional and replacement methods.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2022, v. 85, n. 18, p. 750, doi. 10.1080/15287394.2022.2081640

By:

Ferreira, Paulo Michel Pinheiro;
Sousa, Ian Jhemes Oliveira;
Machado, Kamilla Nunes;
da Silva Neto, Leonel Antônio;
de Freitas, Milena Monteiro;
dos Santos, Ingredy Lopes;
do Nascimento Rodrigues, Débora Caroline;
de Sousa, Rayran Walter Ramos;
dos Reis, Antonielly Campinho;
do Nascimento, Maria Luisa Lima Barreto;
de Menezes, Ag-Anne Pereira Melo;
do Nascimento, Andréa Mendes;
de Oliveira Ferreira, José Roberto;
Peron, Ana Paula;
de Castro e Sousa, João Marcelo

Publication type:

Article

Polydopamine-coated liposomes as pH-sensitive anticancer drug carriers.

Published in:

Journal of Microencapsulation, 2016, v. 33, n. 3, p. 257, doi. 10.3109/02652048.2016.1156176

By:

Zong, Wei;
Hu, Ying;
Su, Yingchun;
Luo, Nan;
Zhang, Xunan;
Li, Qingchuan;
Han, Xiaojun

Publication type:

Article

Bridging US and China to Conquer Cancer.

Published in:

2012

By:

Wancai Yang

Publication type:

Proceeding

A Stability-Indicating RP-HPLC Assay Method for 5-Fluorouracil.

Published in:

Indian Journal of Pharmaceutical Sciences, 2009, v. 71, n. 6, p. 630, doi. 10.4103/0250-474X.59544

By:

SINHA, V. R.;
KUMAR, R. V.;
BHINGE, J. R.

Publication type:

Article

New and emerging HDAC inhibitors for cancer treatment.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 1, p. 30, doi. 10.1172/JCI69738

By:

West, Alison C.;
Johnstone, Ricky W.

Publication type:

Article

miR-31 promotes proliferation of colon cancer cells by targeting E2F2.

Published in:

Biotechnology Letters, 2015, v. 37, n. 3, p. 523, doi. 10.1007/s10529-014-1715-y

By:

Li, Tong;
Luo, Wenjing;
Liu, Kunmei;
Lv, Xiaobo;
Xi, Tao

Publication type:

Article

Human Embryonic Kidney 293 Cells: A Vehicle for Biopharmaceutical Manufacturing, Structural Biology, and Electrophysiology.

Published in:

Cells Tissues Organs, 2018, v. 205, n. 1, p. 1, doi. 10.1159/000485501

By:

Hu, Jianwen;
Han, Jizhong;
Li, Haoran;
Zhang, Xian;
Liu, Lan lan;
Chen, Fei;
Zeng, Bin

Publication type:

Article

Effect of Target Therapy on the Content of Transcription and Growth Factors, Protein Kinase TOR, and Activity of Intracellular Proteases in Patients with Metastatic Renal Cell Carcinoma.

Published in:

Bulletin of Experimental Biology & Medicine, 2016, v. 160, n. 6, p. 798, doi. 10.1007/s10517-016-3313-6

By:

Spirina, L.;
Usynin, E.;
Kondakova, I.;
Yurmazov, Z.;
Slonimskaya, E.

Publication type:

Article

Anticancer drug development: the grand challenges.

Published in:

Nature Reviews Drug Discovery, 2010, v. 9, n. 4, p. 253, doi. 10.1038/nrd3144

By:

Hait, William N.

Publication type:

Article

Nivolumab Active in HPV-Positive Gynecologic Cancers.

Published in:

Oncology Practice Management, 2018, v. 8, n. 1, p. 1

By:

Bankhead, Charles

Publication type:

Article

Targeting the Carbonic Anhydrase Enzyme with Synthesized Benzenesulfonamide Derivatives: Inhibiting Tumor Growth.

Published in:

Journal of Contemporary Medical Sciences, 2023, v. 9, n. 4, p. 245, doi. 10.22317/jcms.v9i4.1404

By:

Abbas, Zainab Kifah;
Naser, Noor H.;
Atiya, Rana Neama

Publication type:

Article

Current Advancement in the Oxadiazole-Based Scaffolds as Anticancer Agents.

Published in:

Polycyclic Aromatic Compounds, 2022, v. 42, n. 7, p. 4183, doi. 10.1080/10406638.2021.1886123

By:

Kapoor, Garima;
Bhutani, Rubina;
Pathak, Dharam Pal;
Chauhan, Garima;
Kant, Ravi;
Grover, Parul;
Nagarajan, Kandasamy;
Siddiqui, Shadab Ahmad

Publication type:

Article

Novel drug approaches in veterinary cancer therapy.

Published in:

Veterinary Ireland Journal, 2014, v. 4, n. 1, p. 27

By:

Polton, Gerry

Publication type:

Article

Topoisomerase IIα, rather than IIβ, is a promising target in development of anti-cancer drugs.

Published in:

Drug Discoveries & Therapeutics, 2012, v. 6, n. 5, p. 230, doi. 10.5582/ddt.2012.v6.5.23

By:

Wang Chen;
Jin Qiu;
Yuemao Shen

Publication type:

Article

Recycling existing drugs for cancer therapy: delivering low cost cancer care.

Published in:

2014

By:

Pantziarka, Pan;
Cairns, Linda

Publication type:

Editorial

Hurdles and delays in access to anti-cancer drugs in Europe.

Published in:

Ecancermedicalscience, 2014, v. 8, n. 474-494, p. 1, doi. 10.3332/ecancer.2014.482

By:

Ades, F.;
Zardavas, D.;
Senterre, C.;
de Azambuja, E.;
Eniu, A.;
Popescu, R.;
Piccart, M.;
Parent, F.

Publication type:

Article

Phase 0 Workshop at the 20th EORTC-NCI-AACR Symposium, Geneva.

Published in:

2008

By:

Camporesi, S.

Publication type:

Conference Paper/Materials

β-Diketones as Scaffolds for Anticancer Drug Design - From Organic Building Blocks to Natural Products and Metallodrug Components.

Published in:

European Journal of Inorganic Chemistry, 2017, v. 2017, n. 12, p. 1655, doi. 10.1002/ejic.201601314

By:

Kljun, Jakob;
Turel, Iztok

Publication type:

Article

Saudi anti-human cancer plants database (SACPD): A collection of plants with anti-human cancer activities.

Published in:

Oncology Reviews, 2018, v. 12, n. 1, p. 14, doi. 10.4081/oncol.2018.349

By:

Al-Zahrani, Ateeq Ahmed

Publication type:

Article

Interferon regulatory factor-8 modulates the development of tumour-induced CD11b+Gr-1+ myeloid cells.

Published in:

Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 9b, p. 3939, doi. 10.1111/j.1582-4934.2009.00685.x

By:

Stewart, Trina J.;
Greeneltch, Kristy M.;
Reid, Julia E.;
Liewehr, David J.;
Steinberg, Seth M.;
Liu, Kebin;
Abrams, Scott I.

Publication type:

Article

Synthesis and Evaluation of Novel 3-Allylseleno-6-Alkylsulfonylpyridazine Derivatives with Potential Anticancer Properties.

Published in:

Bulletin of the Korean Chemical Society, 2017, v. 38, n. 11, p. 1327, doi. 10.1002/bkcs.11292

By:

Kim, Chaewon;
Park, Myung‐Sook

Publication type:

Article

Design, synthesis, and biological evaluation of Helicobacter pylori inosine 5′‐monophosphate dehydrogenase (HpIMPDH) inhibitors.

Published in:

Drug Development Research, 2019, v. 80, n. 1, p. 125, doi. 10.1002/ddr.21467

By:

Sahu, Niteshkumar U.;
Purushothaman, Gayathri;
Thiruvenkatam, Vijay;
Kharkar, Prashant S.

Publication type:

Article

Anticancer drugs: Advancing precision medicine in silico.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 5, p. 311, doi. 10.1038/nrd4619

By:

Cully, Megan

Publication type:

Article

The role of HGF/c-MET signaling pathway in lymphoma.

Published in:

Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0366-y

By:

Bao Quoc Lam;
Lu Dai;
Zhiqiang Qin

Publication type:

Article

SINE (selective inhibitor of nucelar transport) - Translational Science in a New Class of Anti-Cancer Agents.

Published in:

Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 1, doi. 10.1186/s13045-014-0067-3

By:

Gerecitano, John

Publication type:

Article

Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium.

Published in:

Clinical Pharmacology & Therapeutics, 2017, v. 101, n. 5, p. 589, doi. 10.1002/cpt.666

By:

Grossman, RL;
Abel, B;
Angiuoli, S;
Barrett, JC;
Bassett, D;
Bramlett, K;
Blumenthal, GM;
Carlsson, A;
Cortese, R;
DiGiovanna, J;
Davis‐Dusenbery, B;
Dittamore, R;
Eberhard, DA;
Febbo, P;
Fitzsimons, M;
Flamig, Z;
Godsey, J;
Goswami, J;
Gruen, A;
Ortuño, F

Publication type:

Article

Food Effect Studies for Oncology Drug Products.

Published in:

Clinical Pharmacology & Therapeutics, 2017, v. 101, n. 5, p. 606, doi. 10.1002/cpt.610

By:

Parsad, S;
Ratain, MJ

Publication type:

Article

European Medicines Agency Perspective on Oncology Study Design for Marketing Authorization and Beyond.

Published in:

Clinical Pharmacology & Therapeutics, 2017, v. 101, n. 5, p. 577, doi. 10.1002/cpt.612

By:

Jonsson, B;
Martinalbo, J;
Pignatti, F

Publication type:

Article

Drug Development, Trial Design, and Endpoints in Oncology: Adapting to Rapidly Changing Science.

Published in:

Clinical Pharmacology & Therapeutics, 2017, v. 101, n. 5, p. 572, doi. 10.1002/cpt.623

By:

Blumenthal, GM;
Goldberg, KB;
Pazdur, R

Publication type:

Article