Works about ANTIBODY-toxin conjugates

Results: 452

Comparative Efficacy of Ribosome-Inactivating Protein-Containing Immunotoxins in 2D and 3D Models of Sarcoma.

Published in:

Toxins, 2025, v. 17, n. 6, p. 308, doi. 10.3390/toxins17060308

By:

Calafato, Giulia;
Bortolotti, Massimo;
Polito, Letizia;
Bolognesi, Andrea

Publication type:

Article

Bacterial Physiology: A persistent magic spot.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 11, p. 739, doi. 10.1038/nrmicro3134

By:

Kåhrström, Christina Tobin

Publication type:

Article

Monolith affinity chromatography for the rapid quantification of a single‐chain variable fragment immunotoxin.

Published in:

Journal of Separation Science, 2018, v. 41, n. 15, p. 3051, doi. 10.1002/jssc.201800257

By:

Satzer, Peter;
Sommer, Ralf;
Paulsson, Johanna;
Rodler, Agnes;
Zehetner, Romana;
Hofstädter, Klaus;
Klade, Christoph;
Jungbauer, Alois

Publication type:

Article

Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 2, p. 229, doi. 10.1007/s11060-012-0904-6

By:

Huang, Jun;
Li, Yan;
Massague, Joan;
Sicheneder, Andy;
Vallera, Daniel;
Hall, Walter

Publication type:

Article

A novel bispecific ligand-directed toxin designed to simultaneously target EGFR on human glioblastoma cells and uPAR on tumor neovasculature.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 2, p. 255, doi. 10.1007/s11060-010-0392-5

By:

Tsai, Alexander;
Oh, Seunguk;
Chen, Hua;
Shu, Yanqun;
Ohlfest, John;
Vallera, Daniel

Publication type:

Article

Distribution, cellular localization, and therapeutic potential of the tumor-associated antigen Ku70/80 in glioblastoma multiforme.

Published in:

Journal of Neuro-Oncology, 2010, v. 97, n. 2, p. 207, doi. 10.1007/s11060-009-0013-3

By:

Persson, Oscar;
Salford, Leif G.;
Fransson, Johan;
Widegren, Bengt;
Borrebaeck, Carl A. K.;
Holmqvist, Bo

Publication type:

Article

Gigantoxin-4-4D5 scFv is a novel recombinant immunotoxin with specific toxicity against HER2/neu-positive ovarian carcinoma cells.

Published in:

Applied Microbiology & Biotechnology, 2016, v. 100, n. 14, p. 6403, doi. 10.1007/s00253-016-7487-7

By:

Lv, Xinxin;
Zhang, Jian;
Xu, Rui;
Dong, Yuguo;
Sun, Aiyou;
Shen, Yaling;
Wei, Dongzhi

Publication type:

Article

Engineering of bacterial strains and their products for cancer therapy.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 12, p. 5189, doi. 10.1007/s00253-013-4926-6

By:

Bernardes, Nuno;
Chakrabarty, Ananda;
Fialho, Arsenio

Publication type:

Article

Purification of clinical-grade disulfide stabilized antibody fragment variable- Pseudomonas exotoxin conjugate (dsFv-PE38) expressed in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 2, p. 621, doi. 10.1007/s00253-012-4319-2

By:

Jiang, Hua;
Xie, Yueqing;
Burnette, Andrew;
Roach, John;
Giardina, Steven;
Hecht, Toby;
Creekmore, Stephen;
Mitra, Gautam;
Zhu, Jianwei

Publication type:

Article

Gene expression and function study of fusion immunotoxin anti-Her-2-scFv—SEC2 in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2006, v. 70, n. 1, p. 78, doi. 10.1007/s00253-005-0049-z

By:

Xu Ming-Kai;
Zhang Cheng-Gang

Publication type:

Article

Depletion of folate receptor β-expressing macrophages alleviates bleomycin-induced experimental skin fibrosis.

Published in:

Modern Rheumatology, 2014, v. 24, n. 5, p. 816, doi. 10.3109/14397595.2013.879415

By:

Li, Hua;
Nagai, Taku;
Hasui, Kazuhisa;
Matsuyama, Takami

Publication type:

Article

Immunotoxins in cancer therapy: Review and update.

Published in:

International Reviews of Immunology, 2017, v. 36, n. 4, p. 207, doi. 10.1080/08830185.2017.1284211

By:

Akbari, Bahman;
Farajnia, Safar;
Ahdi Khosroshahi, Shiva;
Safari, Fatemeh;
Yousefi, Mohammadreza;
Dariushnejad, Hassan;
Rahbarnia, Leila

Publication type:

Article

Optimization of Chemically Defined Cell Culture Media for Recombinant ONTAK Immunotoxin Production.

Published in:

Iranian Journal of Medical Microbiology, 2014, v. 8, n. 3, p. 51

By:

Heydari, Mohammad;
Robatjazi, Syed Morteza;
Zeinoddini, Mehadi;
darabi, Ehsan

Publication type:

Article

Study of the inflammatory response of immunocytes to polymerized porcine hemoglobin (pPolyHb).

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2016, v. 44, n. 2, p. 448, doi. 10.3109/21691401.2015.1060980

By:

Zhu, Wenjin;
Liu, Fang;
Xin, Jianguo;
Xie, Zhilan;
Su, Boya;
Yan, Chengbin;
Zhang, Jia;
Chen, Chao;
Zhu, Hongli

Publication type:

Article

Mesothelin, a possible target for immunotherapy, is expressed in primary AML cells.

Published in:

European Journal of Haematology, 2007, v. 79, n. 4, p. 281, doi. 10.1111/j.1600-0609.2007.00928.x

By:

Steinbach, Daniel;
Onda, Masanori;
Voigt, Astrid;
Dawczynski, Kristin;
Wittig, Susan;
Hassan, Raffit;
Gruhn, Bernd;
Pastan, Ira

Publication type:

Article

Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma.

Published in:

Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 134, doi. 10.1186/s13045-014-0091-3

By:

Ehrlich, Debra;
Bo Wang;
Wei Lu;
Dowling, Peter;
Ruirong Yuan

Publication type:

Article

Amperometric magnetoimmunoassay for the determination of lipoprotein(a).

Published in:

Microchimica Acta, 2015, v. 182, n. 7/8, p. 1457, doi. 10.1007/s00604-015-1472-1

By:

Kaçar, Ceren;
Torrente-Rodríguez, Rebeca;
Pedrero, María;
Campuzano, Susana;
Kilic, Esma;
Pingarrón, José

Publication type:

Article

Arming antibodies: prospects and challenges for immunoconjugates.

Published in:

Nature Biotechnology, 2005, v. 23, n. 9, p. 1137, doi. 10.1038/nbt1141

By:

Wu, Anna M.;
Senter, Peter D.

Publication type:

Article

Sequence of a symbiont.

Published in:

Nature Biotechnology, 2003, v. 21, n. 11, p. 1294, doi. 10.1038/nbt1103-1294

By:

Williamson, Valerie M.;
Kaya, Harry K.

Publication type:

Article

Taming ricin toxin.

Published in:

Nature Biotechnology, 2003, v. 21, n. 4, p. 372, doi. 10.1038/nbt0403-372

By:

Kreitman, Robert J.

Publication type:

Article

Macrophages and cutaneous inflammation.

Published in:

Nature Biotechnology, 2000, v. 18, n. 1, p. 25, doi. 10.1038/71879

By:

McCormick, Thomas S.;
Stevens, Seth R.;
Kang, Kefei

Publication type:

Article

Resolution of cutaneous inflammation after local elimination of macrophages.

Published in:

Nature Biotechnology, 2000, v. 18, n. 1, p. 48, doi. 10.1038/71908

By:

Thepen, Theo;
van Vuuren, A. J. Hanneke;
Kiekens, Rebecca C. M.;
Damen, Cora A.;
Vooijs, Wim C.;
van de Winkel, Jan G. J.

Publication type:

Article

Role of Striatal Cholinergic Interneurons in Set-Shifting in the Rat.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 25, p. 9424, doi. 10.1523/JNEUROSCI.0490-15.2015

By:

Sho Aoki;
Liu, Andrew W.;
Zucca, Aya;
Zucca, Stefano;
Wickens, Jeffery R.

Publication type:

Article

Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo.

Published in:

British Journal of Cancer, 2013, v. 109, n. 6, p. 1570, doi. 10.1038/bjc.2013.457

By:

Hristodorov, D;
Mladenov, R;
Pardo, A;
Pham, A-T;
Huhn, M;
Fischer, R;
Thepen, T;
Barth, S

Publication type:

Article

hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma.

Published in:

2010

By:

Cocco, E.;
Hu, Z.;
Richter, C. E.;
Bellone, S.;
Casagrande, F.;
Bellone, M.;
Todeschini, P.;
Krikun, G.;
Silasi, D-A.;
Azodi, M.;
Schwartz, P. E.;
Rutherford, T. J.;
Buza, N.;
Pecorelli, S.;
Lockwood, C. J.;
Santin, A. D.

Publication type:

journal article

Cover Feature: <sup>64</sup>Cu tumor labeling with hexadentate picolinic acid‐based bispidine immunoconjugates (Chem. Eur. J. 32/2024).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 32, p. 1, doi. 10.1002/chem.202401745

By:

Kubeil, Manja;
Neuber, Christin;
Starke, Miriam;
Arndt, Claudia;
Rodrigues Loureiro, Liliana;
Hoffmann, Lydia;
Feldmann, Anja;
Bachmann, Michael;
Pietzsch, Jens;
Comba, Peter;
Stephan, Holger

Publication type:

Article

<sup>64</sup>Cu tumor labeling with hexadentate picolinic acid‐based bispidine immunoconjugates.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 32, p. 1, doi. 10.1002/chem.202400366

By:

Kubeil, Manja;
Neuber, Christin;
Starke, Miriam;
Arndt, Claudia;
Rodrigues Loureiro, Liliana;
Hoffmann, Lydia;
Feldmann, Anja;
Bachmann, Michael;
Pietzsch, Jens;
Comba, Peter;
Stephan, Holger

Publication type:

Article

Synthesis of Ursolic Acid Conjugates Containing a Furoxan Moiety.

Published in:

Chemistry of Natural Compounds, 2016, v. 52, n. 3, p. 555, doi. 10.1007/s10600-016-1708-2

By:

Popov, S.;
Kornaukhova, L.;
Shpatov, A.;
Grigor'ev, I.

Publication type:

Article

Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 5, p. 1005, doi. 10.1093/ndt/gft413

By:

Miyazaki, Yoichi;
Shimizu, Akihiro;
Ichikawa, Iekuni;
Hosoya, Tatsuo;
Pastan, Ira;
Matsusaka, Taiji

Publication type:

Article

Keap1 inhibition attenuates glomerulosclerosis.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 4, p. 783, doi. 10.1093/ndt/gfu002

By:

Miyazaki, Yoichi;
Shimizu, Akihiro;
Pastan, Ira;
Taguchi, Keiko;
Naganuma, Eriko;
Suzuki, Takafumi;
Hosoya, Tatsuo;
Yokoo, Takashi;
Saito, Akihiko;
Miyata, Toshio;
Yamamoto, Masayuki;
Matsusaka, Taiji

Publication type:

Article

Utilization of nanobiotechnology in haemodialysis: mock-dialysis experiments on homocysteine.

Published in:

Nephrology Dialysis Transplantation, 2008, v. 23, n. 10, p. 3234

By:

Dimosthenis Stamopoulos;
Penelope Bouziotis;
Dimitra Benaki;
Constantinos Kotsovassilis;
Panagiotis N. Zirogiannis

Publication type:

Article

Tumor Targeting Using Anti-Epidermal Growth Factor Receptor (ior egf/r3) Immunoconjugate with a Tetraaza Macrocyclic Agent (DO3A-EA).

Published in:

Molecular Imaging, 2012, v. 11, n. 5, p. 408, doi. 10.2310/7290.2012.00002

By:

Mishra, Gauri;
Panwar, Puja;
Mishra, Anil K.

Publication type:

Article

Novel recombinant anti-HER2/neu immunotoxin: Design and antitumor efficiency.

Published in:

Biochemistry (00062979), 2014, v. 79, n. 12, p. 1376, doi. 10.1134/S0006297914120128

By:

Sokolova, E.;
Zdobnova, T.;
Stremovskiy, O.;
Balalaeva, I.;
Deyev, S.

Publication type:

Article

Interaction of rat renal glucocorticoid receptor with Hsp90 and Hsp70 upon stress provoked by mercury.

Published in:

Journal of Applied Toxicology, 2007, v. 27, n. 1, p. 43, doi. 10.1002/jat.1182

By:

Brkljačić, Jelena;
Pešić, Tatjana;
Dundjerski, Jadranka;
Matić, Gordana

Publication type:

Article

Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment.

Published in:

Biomedicines, 2022, v. 10, n. 6, p. 1223, doi. 10.3390/biomedicines10061223

By:

Guerrero-Ochoa, Patricia;
Ibáñez-Pérez, Raquel;
Berbegal-Pinilla, Germán;
Aguilar, Diederich;
Marzo, Isabel;
Corzana, Francisco;
Minjárez-Sáenz, Martha;
Macías-León, Javier;
Conde, Blanca;
Raso, Javier;
Hurtado-Guerrero, Ramón;
Anel, Alberto

Publication type:

Article

Antibody-Based Immunotoxins for Colorectal Cancer Therapy.

Published in:

Biomedicines, 2021, v. 9, n. 11, p. 1729, doi. 10.3390/biomedicines9111729

By:

Sanz, Laura;
Ibáñez-Pérez, Raquel;
Guerrero-Ochoa, Patricia;
Lacadena, Javier;
Anel, Alberto

Publication type:

Article

Antibody Conjugates for Sarcoma Therapy: How Far along Are We?

Published in:

Biomedicines, 2021, v. 9, n. 8, p. 978, doi. 10.3390/biomedicines9080978

By:

Polito, Letizia;
Calafato, Giulia;
Bortolotti, Massimo;
Chiarelli Olivari, Cecilia;
Maiello, Stefania;
Bolognesi, Andrea

Publication type:

Article

Immunotoxins Targeting B cell Malignancy—Progress and Problems With Immunogenicity.

Published in:

Biomedicines, 2019, v. 7, n. 1, p. 1, doi. 10.3390/biomedicines7010001

By:

Vallera, Daniel A.;
Kreitman, Robert J.

Publication type:

Article

Immunoconjugates for Osteosarcoma Therapy: Preclinical Experiences and Future Perspectives.

Published in:

Biomedicines, 2018, v. 6, n. 1, p. 19, doi. 10.3390/biomedicines6010019

By:

Mercatelli, Daniele;
Bortolotti, Massimo;
Bazzocchi, Alberto;
Bolognesi, Andrea;
Polito, Letizia

Publication type:

Article

Site-Specific Antibody Conjugation for ADC and Beyond.

Published in:

Biomedicines, 2017, v. 5, n. 4, p. 64, doi. 10.3390/biomedicines5040064

By:

Qun Zhou

Publication type:

Article

Addressing the Immunogenicity of the Cargo and of the Targeting Antibodies with a Focus on Deimmunized Bacterial Toxins and on Antibody-Targeted Human Effector Proteins.

Published in:

Biomedicines, 2017, v. 5, n. 2, p. 28, doi. 10.3390/biomedicines5020028

By:

Grinberg, Yehudit;
Benhar, Itai

Publication type:

Article

Pseudomonas Exotoxin-Based Immunotoxins: Over Three Decades of Efforts on Targeting Cancer Cells With the Toxin.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.781800

By:

Havaei, Seyed Mehdi;
Aucoin, Marc G.;
Jahanian-Najafabadi, Ali

Publication type:

Article

Targeted Diphtheria Toxin-Based Therapy: A Review Article.

Published in:

Frontiers in Microbiology, 2019, p. 1, doi. 10.3389/fmicb.2019.02340

By:

Shafiee, Fatemeh;
Aucoin, Marc G.;
Jahanian-Najafabadi, Ali

Publication type:

Article

Essential role of toxin A in C. difficile 027 and reference strain supernatant-mediated disruption of Caco-2 intestinal epithelial barrier function.

Published in:

Clinical & Experimental Immunology, 2008, v. 153, n. 3, p. 439, doi. 10.1111/j.1365-2249.2008.03690.x

By:

Sutton, P. A.;
Li, S.;
Webb, J.;
Solomon, K.;
Brazier, J.;
Mahida, Y. R.

Publication type:

Article

A dominant linear B-cell epitope of ricin A-chain is the target of a neutralizing antibody response in Hodgkin's lymphoma patients treated with an anti-CD25 immunotoxin.

Published in:

Clinical & Experimental Immunology, 2004, v. 136, n. 2, p. 365, doi. 10.1111/j.1365-2249.2004.02442.x

By:

CASTELLETTI, D.;
FRACASSO, G.;
RIGHETTI, S.;
TRIDENTE, G.;
SCHNELL, R.;
ENGERT, A.;
COLOMBATTI, M.

Publication type:

Article

Identification of ricin A-chain HLA class II-restricted epitopes by human T-cell clones.

Published in:

Clinical & Experimental Immunology, 2001, v. 125, n. 3, p. 391, doi. 10.1046/j.1365-2249.2001.01525.x

By:

Tommasi, M.;
Castelletti, D.;
Pasti, M.;
Fracasso, G.;
Lorenzetti, I.;
Sartoris, S.;
Pera, C.;
Ferrara, G. B.;
Tridente, G.;
Colombatti, M.

Publication type:

Article

Characterization of the increased cytotoxicity of gelonin anti--T cell immunoconjugates compared with ricin A chain immunoconjugates.

Published in:

Clinical & Experimental Immunology, 1994, v. 97, n. 1, p. 10, doi. 10.1111/1365-2249.ep15987800

By:

Fishwild, D. M.;
Wu, H.-M.;
Carroll, S. F.;
Bernhard, S.L.

Publication type:

Article

A comparison of anti-lymphocyte immunotoxins containing different ribosome-inactivating proteins and antibodies.

Published in:

Clinical & Experimental Immunology, 1992, v. 89, n. 3, p. 341

By:

Bolognesi, A.;
Tazzari, P. L.;
Tassi, C.;
Gromo, G.;
Gobbi, M.;
Stirpe, F.

Publication type:

Article

Potentiation of a weakly active ricin A chain immunotoxin recognizing the neural cell adhesion molecule.

Published in:

Clinical & Experimental Immunology, 1992, v. 89, n. 3, p. 336

By:

Derbyshire, E. J.;
Stahel, R. A.;
Wawrzynczak, E. J.

Publication type:

Article

Reduction of graft-versus-host reactivity after small bowel transplantation: ex vivo treatment of intestinal allografts with an anti-T cell immunotoxin.

Published in:

Clinical & Experimental Immunology, 1992, v. 88, n. 2, p. 220

By:

Ingham Clark, C. L.;
Smith, G. J.;
Crane, P. W.;
Price, B. A.;
Lear, P. A.;
Fabre, J. W.;
Wood, R. F. M.

Publication type:

Article