Works matching DE "ANTIBODY-toxin conjugates"

Results: 450

Engineered probiotic-mediated intratumoral delivery and controlled release of bacterial collagenase for cancer therapy.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 1, p. 226, doi. 10.1016/j.synbio.2024.09.001

By:

Hong-Rui Li;
Bang-Ce Ye

Publication type:

Article

Understanding Evaluation and Management of Primary Cutaneous and Systemic ALCL.

Published in:

Oncology (08909091), 2010, v. 24, n. 7, p. 594

By:

Vose, Julie M.

Publication type:

Article

Bacterial Physiology: A persistent magic spot.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 11, p. 739, doi. 10.1038/nrmicro3134

By:

Kåhrström, Christina Tobin

Publication type:

Article

Construction of sea anemone cytolysin-based immunotoxins for selective killing of cancer cells.

Published in:

Revista Cubana de Física, 2009, v. 26, n. 1, p. 15

By:

Tejuca, M.;
Pérez-Barzaga, V.;
Pazos, F.;
Álvarez, C.;
Lanio, M. E.

Publication type:

Article

Stabilisation of immunoconjugates by trehalose.

Published in:

Biotechnology Letters, 2000, v. 22, n. 5, p. 417, doi. 10.1023/A:1005605616356

By:

Esteves, Maria Izabel;
Quintilio, Wagner;
Sato, Rony A.;
Raw, Isaías;
de Araujo, Pedro Soares;
da Costa, Maria Helena Bueno

Publication type:

Article

Effects of complete immunotoxin lesions of the cholinergic basal forebrain on fear conditioning and spatial learning.

Published in:

Hippocampus, 2004, v. 14, n. 2, p. 244, doi. 10.1002/hipo.10169

By:

Karyn M. Frick;
Jeansok J. Kim;
Mark G. Baxter

Publication type:

Article

Selective lesion of medial septal cholinergic neurons followed by a mini-stroke impairs spatial learning in rats.

Published in:

Experimental Brain Research, 2009, v. 193, n. 1, p. 29, doi. 10.1007/s00221-008-1592-5

By:

Craig, Laura A.;
Hong, Nancy S.;
Kopp, Joelle;
McDonald, Robert J.

Publication type:

Article

Gene expression and function study of fusion immunotoxin anti-Her-2-scFv—SEC2 in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2006, v. 70, n. 1, p. 78, doi. 10.1007/s00253-005-0049-z

By:

Xu Ming-Kai;
Zhang Cheng-Gang

Publication type:

Article

In vitro and preclinical targeted alpha therapy of human prostate cancer with Bi-213 labeled J591 antibody against the prostate specific membrane antigen.

Published in:

Prostate Cancer & Prostatic Diseases, 2002, v. 5, n. 1, p. 36, doi. 10.1038/sj.pcan.4500543

By:

Li, Y.;
Tian, Z.;
Rizvi, S. M. A.;
Bander, N. H.;
Allen, B. J.

Publication type:

Article

A comparison of anti-lymphocyte immunotoxins containing different ribosome-inactivating proteins and antibodies.

Published in:

Clinical & Experimental Immunology, 1992, v. 89, n. 3, p. 341

By:

Bolognesi, A.;
Tazzari, P. L.;
Tassi, C.;
Gromo, G.;
Gobbi, M.;
Stirpe, F.

Publication type:

Article

Potentiation of a weakly active ricin A chain immunotoxin recognizing the neural cell adhesion molecule.

Published in:

Clinical & Experimental Immunology, 1992, v. 89, n. 3, p. 336

By:

Derbyshire, E. J.;
Stahel, R. A.;
Wawrzynczak, E. J.

Publication type:

Article

Reduction of graft-versus-host reactivity after small bowel transplantation: ex vivo treatment of intestinal allografts with an anti-T cell immunotoxin.

Published in:

Clinical & Experimental Immunology, 1992, v. 88, n. 2, p. 220

By:

Ingham Clark, C. L.;
Smith, G. J.;
Crane, P. W.;
Price, B. A.;
Lear, P. A.;
Fabre, J. W.;
Wood, R. F. M.

Publication type:

Article

Cytotoxicity against human peripheral blood mononuclear cells and T cell lines mediated by anti-T cell immunotoxins in the absence of added potentiator.

Published in:

Clinical & Experimental Immunology, 1991, v. 86, n. 3, p. 506, doi. 10.1111/j.1365-2249.1991.tb02961.x

By:

Fishwild, D. M.;
Staskawicz, M. O.;
Wu, H.-M.;
Carroll, S. F.

Publication type:

Article

The in-vitro inhibition of rat alloantigen presentation by immunotoxins--implications for allografting.

Published in:

Clinical & Experimental Immunology, 1989, v. 76, n. 1, p. 132

By:

Wiley, K. N.;
Clark, A.;
Fox, M.

Publication type:

Article

Humoral immune responses to XMMCO-791-RTA immunotoxin in colorectal cancer patients.

Published in:

Clinical & Experimental Immunology, 1989, v. 75, n. 2, p. 258

By:

Durrant, L. G.;
Byers, V. S.;
Scannon, P. J.;
Rodvien, R.;
Grant, K.;
Robins, R. A.;
Marksman, R. A.;
Baldwin, R. W.

Publication type:

Article

Effect of specific anti-human leukaemia immunotoxins on the colony formation by human haematopoietic progenitors and by human leukaemia cells.

Published in:

Clinical & Experimental Immunology, 1985, v. 60, n. 3, p. 496

By:

Tebbi, C. K.;
Chervinsky, D.;
Seon, B. K.

Publication type:

Article

A comparison of an anti-CD25 immunotoxin, Ontak and anti-CD25 microbeads for their ability to deplete alloreactive T cells in vitro.

Published in:

Bone Marrow Transplantation, 2006, v. 37, n. 6, p. 559, doi. 10.1038/sj.bmt.1705286

By:

Vaclavkova, P.;
Y. Cao;
L. K. Wu;
Michalek, J.;
Vitetta, E. S.

Publication type:

Article

Radioimmunoconjugates in acute leukemia treatment: the future is radiant.

Published in:

Bone Marrow Transplantation, 2005, v. 36, n. 12, p. 1021, doi. 10.1038/sj.bmt.1705182

By:

Kotzerke, J.;
Bunjes, D.;
Scheinberg, D. A.

Publication type:

Article

Clinical targeting recombinant immunotoxins for cancer therapy.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 3645, doi. 10.2147/OTT.S134584

By:

Meng Li;
Zeng-Shan Liu;
Xi-Lin Liu;
Qi Hui;
Shi-Ying Lu;
Lin-Lin Qu;
Yan-Song Li;
Yu Zhou;
Hong-Lin Ren;
Pan Hu

Publication type:

Article

Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13104-019-4337-6

By:

Zhu, Yuyi;
Weldon, John E.

Publication type:

Article

Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210608

By:

Yu, Xin;
Dobrikov, Mikhail;
Keir, Stephen T.;
Gromeier, Matthias;
Pastan, Ira H.;
Reisfeld, Ralph;
Bigner, Darell D.;
Chandramohan, Vidyalakshmi

Publication type:

Article

Chimeric molecules for cancer therapy.

Published in:

1998

By:

FitzGerald

Publication type:

Abstract

Cytotoxic Potency of CD22-Ricin A Depends on Intracellular Routing Rather than on the Number of Internalized Molecules.

Published in:

Scandinavian Journal of Immunology, 1995, v. 41, n. 6, p. 563, doi. 10.1111/j.1365-3083.1995.tb03608.x

By:

Van Horssen, P. J.;
Van Oosterhout, Y. V. J. M.;
De Witte, T.;
Preijers, F. W. M. B.

Publication type:

Article

Selective Killing of CD4+ and CD8+ Cells with Immunotoxins Containing Saporin.

Published in:

Scandinavian Journal of Immunology, 1989, v. 30, n. 3, p. 369, doi. 10.1111/j.1365-3083.1989.tb01223.x

By:

Barbieri, L.;
Bolognesi, A.;
Dinota, A.;
Lappi, D.A.;
Soria, M.;
Tazzari, P.L.;
Stirpe, F.

Publication type:

Article

Human T Lymphocyte Differentiation Antigens as Target for Immunotoxins or Complement- Mediated Cytotoxicity.

Published in:

Scandinavian Journal of Immunology, 1988, v. 28, n. 2, p. 185, doi. 10.1111/j.1365-3083.1988.tb02430.x

By:

Preijers, F. W. M. B.;
de Witte, T.;
Rijke-Schilder, G. P. M.;
Tax, W. J. M.;
Wessels, J. M. C.;
Haanen, C.;
Capel, P. J. A.

Publication type:

Article

Different Susceptibilities of Normal T Cells and T Cell Lines to Immunotoxins.

Published in:

Scandinavian Journal of Immunology, 1988, v. 27, n. 5, p. 533, doi. 10.1111/j.1365-3083.1988.tb02380.x

By:

Preijers, F. W. M. B.;
Tax, W. J. M.;
Wessels, J. M. C.;
Capel, P. J. A.;
de Witte, T.;
Haanen, C.

Publication type:

Article

Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems.

Published in:

Microbial Cell Factories, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12934-015-0202-z

By:

Cristina, Pietro Della;
Castagna, Monica;
Lombardi, Alessio;
Barison, Erika;
Tagliabue, Giovanni;
Ceriotti, Aldo;
Koutris, Ilias;
Di Leandro, Luana;
Giansanti, Francesco;
Vago, Riccardo;
Ippoliti, Rodolfo;
Flavell, Sopsamorn U.;
Flavell, David J.;
Colombatti, Marco;
Fabbrini, Maria Serena

Publication type:

Article

Immunotoxin Complementation of HAART to Deplete Persisting HIV-Infected Cell Reservoirs.

Published in:

2010

By:

Berger, Edward A.;
Pastan, Ira

Publication type:

Opinion

Parallels between Pathogens and Gluten Peptides in Celiac Sprue.

Published in:

PLoS Pathogens, 2008, v. 4, n. 2, p. 0001, doi. 10.1371/journal.ppat.0040034

By:

Bethune, Michael T.;
Khosla, Chaitan

Publication type:

Article

Preparation and preliminary bioevaluation studies of 68Ga‐NOTA‐rituximab fragments as radioimmunoscintigraphic agents for non‐Hodgkin lymphoma.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2019, v. 62, n. 12, p. 850, doi. 10.1002/jlcr.3803

By:

Suman, Shishu Kant;
Kameswaran, Mythili;
Pandey, Usha;
Sarma, Haladhar Dev;
Dash, Ashutosh

Publication type:

Article

Preparation of 177Lu‐labeled Nimotuzumab for radioimmunotherapy of EGFR‐positive cancers: Comparison of DOTA and CHX‐A″‐DTPA as bifunctional chelators.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2019, v. 62, n. 4, p. 158, doi. 10.1002/jlcr.3707

By:

Pandey, Usha;
Kameswaran, Mythili;
Gamre, Naresh;
Dash, Ashutosh

Publication type:

Article

90Y/177Lu-labelled Cetuximab immunoconjugates: radiochemistry optimization to clinical dose formulation.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2016, v. 59, n. 9, p. 354, doi. 10.1002/jlcr.3413

By:

Chakravarty, Rubel;
Chakraborty, Sudipta;
Sarma, Haladhar Dev;
Nair, K. V. Vimalnath;
Rajeswari, Ardhi;
Dash, Ashutosh

Publication type:

Article

Transferrin Receptor-Mediated Endocytosis: A Useful Target for Cancer Therapy.

Published in:

Journal of Membrane Biology, 2014, v. 247, n. 4, p. 291, doi. 10.1007/s00232-014-9637-0

By:

Tortorella, Stephanie;
Karagiannis, Tom

Publication type:

Article

Efficient targeting of CD13 on cancer cells by the immunotoxin scFv13-ETA′ and the bispecific scFv [13xds16].

Published in:

Journal of Cancer Research & Clinical Oncology, 2017, v. 143, n. 11, p. 2159, doi. 10.1007/s00432-017-2468-5

By:

Grieger, Elena;
Gresch, Gerrit;
Niesen, Judith;
Woitok, Mira;
Barth, Stefan;
Fischer, Rainer;
Fendel, Rolf;
Stein, Christoph

Publication type:

Article

Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2017, v. 143, n. 10, p. 2025, doi. 10.1007/s00432-017-2472-9

By:

Kessler, Claudia;
Pardo, Alessa;
Tur, Mehmet;
Gattenlöhner, Stefan;
Fischer, Rainer;
Kolberg, Katharina;
Barth, Stefan

Publication type:

Article

Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities.

Published in:

Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 12, p. 2079, doi. 10.1007/s00432-015-1975-5

By:

Niesen, Judith;
Stein, Christoph;
Brehm, Hannes;
Hehmann-Titt, Grit;
Fendel, Rolf;
Melmer, Georg;
Fischer, Rainer;
Barth, Stefan

Publication type:

Article

In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells.

Published in:

Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 6, p. 1049, doi. 10.1007/s00432-014-1884-z

By:

Niesen, Judith;
Brehm, Hannes;
Stein, Christoph;
Berges, Nina;
Pardo, Alessa;
Fischer, Rainer;
Haaf, Andre;
Gattenlöhner, Stefan;
Tur, Mehmet;
Barth, Stefan

Publication type:

Article

In vitro and in vivo anti-tumor activities of anti-EGFR single-chain variable fragment fused with recombinant gelonin toxin.

Published in:

Journal of Cancer Research & Clinical Oncology, 2012, v. 138, n. 7, p. 1081, doi. 10.1007/s00432-012-1181-7

By:

Zhou, Xikun;
Qiu, Ji;
Wang, Zhen;
Huang, Nongyu;
Li, Xiaolei;
Li, Qian;
Zhang, Yinbing;
Zhao, Chengjian;
Luo, Can;
Zhang, Nannan;
Teng, Xiu;
Chen, Zhongwen;
Liu, Xiao;
Yu, Xianlian;
Wu, Wenling;
Wei, Yu-quan;
Li, Jiong

Publication type:

Article

Synergistic cytotoxicity of a prostate cancer-specific immunotoxin in combination with the BH3 mimetic ABT-737.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 3, p. 413, doi. 10.1007/s00262-017-2097-5

By:

Noll, Theresa;
Schultze-Seemann, Susanne;
Kuckuck, Irina;
Michalska, Marta;
Wolf, Philipp

Publication type:

Article

Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 2, p. 329, doi. 10.1007/s00262-017-2101-0

By:

Yuan, Xiaopeng;
Yang, Mingjuan;
Chen, Xiang;
Zhang, Xuhua;
Sukhadia, Shrey;
Musolino, Najia;
Bao, Huijing;
Chen, Tingtao;
Xu, Chen;
Wang, Qirui;
Santoro, Stephen;
Ricklin, Daniel;
Hu, Jia;
Lin, Ruihe;
Yang, Wei;
Li, Zhijun;
Qin, Weijun;
Zhao, Aizhi;
Scholler, Nathalie;
Coukos, George

Publication type:

Article

Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma.

Published in:

Cancer Immunology, Immunotherapy, 2017, v. 66, n. 9, p. 1217, doi. 10.1007/s00262-017-2013-z

By:

Gilabert-Oriol, Roger;
Furness, Sebastian;
Stringer, Brett;
Weng, Alexander;
Fuchs, Hendrik;
Day, Bryan;
Kourakis, Angela;
Boyd, Andrew;
Hare, David;
Thakur, Mayank;
Johns, Terrance;
Wookey, Peter

Publication type:

Article

Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.

Published in:

Cancer Immunology, Immunotherapy, 2017, v. 66, n. 3, p. 367, doi. 10.1007/s00262-016-1937-z

By:

Yuan, Xiaopeng;
Yang, Mingjuan;
Chen, Xiang;
Zhang, Xuhua;
Sukhadia, Shrey;
Musolino, Najia;
Bao, Huijing;
Chen, Tingtao;
Xu, Chen;
Wang, Qirui;
Santoro, Stephen;
Ricklin, Daniel;
Hu, Jia;
Lin, Ruihe;
Yang, Wei;
Li, Zhijun;
Qin, Weijun;
Zhao, Aizhi

Publication type:

Article

Systemic delivery of chTNT-3/CpG immunoconjugates for immunotherapy in murine solid tumor models.

Published in:

Cancer Immunology, Immunotherapy, 2016, v. 65, n. 5, p. 511, doi. 10.1007/s00262-016-1813-x

By:

Jang, Julie;
Khawli, Leslie;
Canter, David;
Hu, Peisheng;
Zhu, Tian;
Wu, Brian;
Angell, Trevor;
Li, Zhongjun;
Epstein, Alan

Publication type:

Article

Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo.

Published in:

Cancer Immunology, Immunotherapy, 2015, v. 64, n. 12, p. 1575, doi. 10.1007/s00262-015-1763-8

By:

Cremer, Christian;
Braun, Hanna;
Mladenov, Radoslav;
Schenke, Lea;
Cong, Xiaojing;
Jost, Edgar;
Brümmendorf, Tim;
Fischer, Rainer;
Carloni, Paolo;
Barth, Stefan;
Nachreiner, Thomas

Publication type:

Article

ADAM17-overexpressing breast cancer cells selectively targeted by antibody-toxin conjugates.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 3, p. 411, doi. 10.1007/s00262-012-1346-x

By:

Trad, Ahmad;
Hansen, Hinrich;
Shomali, Mohammad;
Peipp, Matthias;
Klausz, Katja;
Hedemann, Nina;
Yamamoto, Kosuke;
Mauermann, André;
Desel, Christine;
Lorenzen, Inken;
Lemke, Hilmar;
Rose-John, Stefan;
Grötzinger, Joachim

Publication type:

Article

In vitro and in vivo effects of an anti-mouse endoglin (CD105)-immunotoxin on the early stages of mouse B16MEL4A5 melanoma tumours.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 3, p. 541, doi. 10.1007/s00262-012-1357-7

By:

Muñoz, Raquel;
Arias, Yolanda;
Ferreras, José;
Jiménez, Pilar;
Langa, Carmen;
Rojo, María;
Gayoso, Manuel;
Córdoba-Díaz, Damián;
Bernabéu, Carmelo;
Girbés, Tomás

Publication type:

Article

Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity.

Published in:

Cancer Immunology, Immunotherapy, 2012, v. 61, n. 11, p. 2055, doi. 10.1007/s00262-012-1264-y

By:

Schettini, Jorge;
Kidiyoor, Amritha;
Besmer, Dahlia;
Tinder, Teresa;
Roy, Lopamudra;
Lustgarten, Joseph;
Gendler, Sandra;
Mukherjee, Pinku

Publication type:

Article

In vivo imaging of immunotoxin treatment using Katushka-transfected A-431 cells in a murine xenograft tumour model.

Published in:

Cancer Immunology, Immunotherapy, 2012, v. 61, n. 10, p. 1617, doi. 10.1007/s00262-012-1219-3

By:

Pardo, Alessa;
Stöcker, Michael;
Kampmeier, Florian;
Melmer, Georg;
Fischer, Rainer;
Thepen, Theo;
Barth, Stefan

Publication type:

Article

Targeting of a developmentally regulated epitope of CD43 for the treatment of acute leukemia.

Published in:

Cancer Immunology, Immunotherapy, 2011, v. 60, n. 12, p. 1697, doi. 10.1007/s00262-011-1066-7

By:

Jeon, Yoon;
Min, Hye;
Lee, Yoo;
Kang, Byung;
Kim, Eun;
Park, Hyo;
Bae, Youngmee;
Lee, Hyun;
Park, Weon;
Song, Hyung;
Jung, Kyeong;
Park, Seong

Publication type:

Article

Use of CD40L immunoconjugates to overcome the defective immune response to vaccines for infections and cancer in the aged.

Published in:

Cancer Immunology, Immunotherapy, 2009, v. 58, n. 12, p. 1949, doi. 10.1007/s00262-009-0718-3

By:

Yu Cheng Tang;
Thoman, Marilyn;
Linton, Phyllis-Jean;
Deisseroth, Albert

Publication type:

Article