Works matching DE "ANTIBODY-drug conjugates"
Results: 1217
The effectiveness and safety of RC48 alone or in combination with PD-1 inhibitors for locally advanced or metastatic urothelial carcinoma: a multicenter, real-world study.
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- Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06237-4
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Is ADC a rising star in solid tumor? An umbrella review of systematic reviews and meta-analyses.
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- BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-13726-8
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BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting.
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- Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01675-5
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Drug Treatment Direction Based on the Molecular Mechanism of Breast Cancer Brain Metastasis.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 262, doi. 10.3390/ph18020262
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A Dramatic Clinical Response to Trastuzumab-Deruxtecan in a Patient with HER-2 Low Breast Cancer with Untreated Leptomeningeal Metastasis and Hydrocephalus.
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- Current Oncology, 2025, v. 32, n. 2, p. 81, doi. 10.3390/curroncol32020081
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Model-informed development of a cost-saving dosing regimen for enfortumab vedotin.
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- Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-025-04764-x
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Site‐Selective Protein Conjugation by a Multicomponent Ugi Reaction.
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- Chemistry - A European Journal, 2024, v. 30, n. 14, p. 1, doi. 10.1002/chem.202303242
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Fast Cysteine Bioconjugation Chemistry.
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- Chemistry - A European Journal, 2022, v. 28, n. 66, p. 1, doi. 10.1002/chem.202201843
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New Opportunities for the Utilization of the Sulfoximine Group in Medicinal Chemistry from the Drug Designer's Perspective**.
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- Chemistry - A European Journal, 2022, v. 28, n. 56, p. 1, doi. 10.1002/chem.202201993
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Cover Feature: Investigating a Boronate‐Affinity‐Guided Acylation Reaction for Labelling Native Antibodies (Chem. Eur. J. 17/2022).
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- Chemistry - A European Journal, 2022, v. 28, n. 17, p. 1, doi. 10.1002/chem.202200536
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Investigating a Boronate‐Affinity‐Guided Acylation Reaction for Labelling Native Antibodies.
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- Chemistry - A European Journal, 2022, v. 28, n. 17, p. 1, doi. 10.1002/chem.202104178
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Azobenzene‐Based Linker Strategy for Selective Activation of Antibody–Drug Conjugates.
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- Angewandte Chemie, 2024, v. 136, n. 16, p. 1, doi. 10.1002/ange.202310318
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Stimuli‐Responsive PROTACs for Controlled Protein Degradation.
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- Angewandte Chemie, 2023, v. 135, n. 39, p. 1, doi. 10.1002/ange.202306824
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A Cysteine‐Directed Proximity‐Driven Crosslinking Method for Native Peptide Bicyclization.
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- Angewandte Chemie, 2023, v. 135, n. 31, p. 1, doi. 10.1002/ange.202306813
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Self‐Assembled L–DNA Linkers for Rapid Construction of Multi‐Specific Antibody‐Drug Conjugates Library.
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- Angewandte Chemie, 2023, v. 135, n. 27, p. 1, doi. 10.1002/ange.202302805
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A Traceless Site‐Specific Conjugation on Native Antibodies Enables Efficient One‐Step Payload Assembly.
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- Angewandte Chemie, 2022, v. 134, n. 36, p. 1, doi. 10.1002/ange.202204132
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Engineering Enzyme‐Cleavable Oligonucleotides by Automated Solid‐Phase Incorporation of Cathepsin B Sensitive Dipeptide Linkers.
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- Angewandte Chemie, 2022, v. 134, n. 13, p. 1, doi. 10.1002/ange.202114016
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Diazaborines Are a Versatile Platform to Develop ROS‐Responsive Antibody Drug Conjugates**.
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- Angewandte Chemie, 2021, v. 133, n. 49, p. 26118, doi. 10.1002/ange.202109835
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Directed Evolution of an Improved Aminoacyl‐tRNA Synthetase for Incorporation of L‐3,4‐Dihydroxyphenylalanine (L‐DOPA).
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- Angewandte Chemie, 2021, v. 133, n. 27, p. 14937, doi. 10.1002/ange.202100579
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Protein–Antibody Conjugates (PACs): A Plug‐and‐Play Strategy for Covalent Conjugation and Targeted Intracellular Delivery of Pristine Proteins.
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- Angewandte Chemie, 2021, v. 133, n. 23, p. 12923, doi. 10.1002/ange.202103106
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Titelbild: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt<sup>II</sup> Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates (Angew. Chem. 6/2021).
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- Angewandte Chemie, 2021, v. 133, n. 6, p. 2741, doi. 10.1002/ange.202016966
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An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the Pt<sup>II</sup> Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates.
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- Angewandte Chemie, 2021, v. 133, n. 6, p. 3045, doi. 10.1002/ange.202011593
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Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics.
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- Angewandte Chemie, 2020, v. 132, n. 51, p. 23245, doi. 10.1002/ange.202010090
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Chemoselective and Site‐Selective Lysine‐Directed Lysine Modification Enables Single‐Site Labeling of Native Proteins.
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- Angewandte Chemie, 2020, v. 132, n. 26, p. 10418, doi. 10.1002/ange.202000062
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Ethynylphosphonamidates for the Rapid and Cysteine‐Selective Generation of Efficacious Antibody–Drug Conjugates.
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- Angewandte Chemie, 2019, v. 131, n. 34, p. 11757, doi. 10.1002/ange.201904193
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AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies.
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- Angewandte Chemie, 2019, v. 131, n. 17, p. 5648, doi. 10.1002/ange.201814215
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Transition of average drug‐to‐antibody ratio of trastuzumab deruxtecan in systemic circulation in monkeys using a hybrid affinity capture liquid chromatography‐tandem mass spectrometry.
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- Biopharmaceutics & Drug Disposition, 2023, v. 44, n. 5, p. 380, doi. 10.1002/bdd.2371
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Synthesis and Pharmacological Evaluation of New Chemical Entities Based on Paracetamol and Their Ibuprofen Conjugates as Novel and Superior Analgesic and Anti-Inflammatory Candidates.
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- Pharmaceutical Chemistry Journal, 2014, v. 48, n. 2, p. 109, doi. 10.1007/s11094-014-1059-x
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A synopsis of recent developments defining how N-glycosylation impacts immunoglobulin G structure and function.
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- Glycobiology, 2020, v. 30, n. 4, p. 214, doi. 10.1093/glycob/cwz068
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Proteolysis targeting chimera (PROTAC)-driven antibody internalization of oncogenic cell surface receptors.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07439-0
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Submerged fermentation of Streptomyces uncialis providing a biotechnology platform for uncialamycin biosynthesis, engineering, and production.
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- Journal of Industrial Microbiology & Biotechnology, 2021, v. 48, n. 3/4, p. 1, doi. 10.1093/jimb/kuab025
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Submerged fermentation of Streptomyces uncialis providing a biotechnology platform for uncialamycin biosynthesis, engineering, and production.
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- Journal of Industrial Microbiology & Biotechnology, 2021, p. 1, doi. 10.1093/jimb/kuab025
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Metabolism of bioconjugate therapeutics: why, when, and how?
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- Drug Metabolism Reviews, 2020, v. 52, n. 1, p. 66, doi. 10.1080/03602532.2020.1716784
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Neoadjuvant chemotherapy efficacy and prognosis in HER2-low and HER2-zero breast cancer patients by HR status: a retrospective study in China.
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- PeerJ, 2024, p. 1, doi. 10.7717/peerj.17492
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Enthusiasm for Antibody–Drug Conjugates.
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- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 20, p. 1493, doi. 10.1093/jnci/djr422
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Antibody-drug conjugates targeting DDR1 as a novel strategy for treatment of breast cancer.
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- Journal of Drug Targeting, 2024, v. 32, n. 10, p. 1295, doi. 10.1080/1061186X.2024.2386621
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The activation mechanism and antibody binding mode for orphan GPR20.
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- Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00520-8
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High-Sensitivity Immunohistochemistry Method Using a Combination of Fluorescent Nanoparticles and Tyramide Linker.
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- Analytical Letters, 2023, v. 56, n. 7, p. 1206, doi. 10.1080/00032719.2022.2123498
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Trastuzumab and its radioimmunoconjugates in treatment of cancer.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2016, v. 62, p. 417
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Approaches in evaluation of freeze-dried antibody conjugates.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2016, v. 62, p. 389
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Preclinical studies for evaluation of antitumor effects and normal tissue toxicity of antibody conjugates.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2016, v. 62, p. 257
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Current status and research directions in acute myeloid leukemia.
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- Blood Cancer Journal, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41408-024-01143-2
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Real-world experience of patients with multiple myeloma receiving ide-cel after a prior BCMA-targeted therapy.
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- Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00886-8
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EGFR-targeting RNase A-cetuximab antibody-drug conjugate induces ROS-mediated apoptosis to overcome drug resistance in KRAS mutant cancer cells.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-85856-9
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Efficacy and prognosis of HER2-Low and HER2-Zero in triple-negative breast cancer after neoadjuvant chemotherapy.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67795-z
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A simple and highly sensitive LC–MS workflow for characterization and quantification of ADC cleavable payloads.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-61522-4
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An Anti-CD7 Antibody–Drug Conjugate Target Showing Potent Antitumor Activity for T-Lymphoblastic Leukemia (T-ALL).
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- Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 106, doi. 10.3390/biom14010106
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Evaluation of B7-H3 Targeted Immunotherapy in a 3D Organoid Model of Craniopharyngioma.
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- Biomolecules (2218-273X), 2022, v. 12, n. 12, p. 1744, doi. 10.3390/biom12121744
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Race for the Cure: From the Oldest to the Newest Monoclonal Antibodies for Multiple Myeloma Treatment.
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- Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1146, doi. 10.3390/biom12081146
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Single Domain Antibodies as Carriers for Intracellular Drug Delivery: A Proof of Principle Study.
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- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 927, doi. 10.3390/biom11070927
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