Works matching DE "AMYLOID beta-protein"

Results: 4925

Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates.

Published in:

Journal of Parkinson's Disease, 2018, v. 8, n. 3, p. 405, doi. 10.3233/JPD-181365

By:

Hashimoto, Makoto;
Ho, Gilbert;
Takamatsu, Yoshiki;
Shimizu, Yuka;
Sugama, Shuei;
Takenouchi, Takato;
Waragai, Masaaki;
Masliah, Eliezer

Publication type:

Article

Muscarinic M1 Receptor Coupling to G-protein is Intact in Parkinson's Disease Dementia.

Published in:

Journal of Parkinson's Disease, 2016, v. 6, n. 4, p. 733, doi. 10.3233/JPD-160932

By:

Leex, Jasinda H.;
Francis, Paul T.;
Ballard, Clive G.;
Aarsland, Dag;
Kalaria, Raj N.;
Wong, Peter T.-H.;
Chen, Christopher P.;
Lai, Mitchell K. P.

Publication type:

Article

Exploring 2‐Thioxo‐1,2,3,4‐tetrahydropyrimidines as Dual Acting GSK‐3β/Aβ Aggregation Inhibitors: Implications for Alzheimer's Disease Treatment.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70112

By:

Sukanya, Sukanya;
Bellver‐Sanchis, Aina;
Choudhary, Bhanwar Singh;
Kumar, Sunil;
Pérez, Belén;
Rodríguez, Antón Leandro Martínez;
Brea, Jose;
Escolano, Carmen;
Griñán‐Ferré, Christian;
Malik, Ruchi

Publication type:

Article

Correlation of early-phase β-amyloid positron-emission-tomography and neuropsychological testing in patients with Alzheimer's disease.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2025, v. 52, n. 8, p. 2918, doi. 10.1007/s00259-025-07175-5

By:

Völter, Friederike;
Eckenweber, Sebastian;
Scheifele, Maximilian;
Eckenweber, Florian;
Hirsch, Fabian;
Franzmeier, Nicolai;
Kreuzer, Annika;
Griessl, Maria;
Steward, Anna;
Janowitz, Daniel;
Palleis, Carla;
Bernhardt, Alexander;
Vöglein, Jonathan;
Stockbauer, Anna;
Rauchmann, Boris-Stephan;
Schöberl, Florian;
Wlasich, Elisabeth;
Buerger, Katharina;
Wagemann, Olivia;
Perneczky, Robert

Publication type:

Article

Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02890-7

By:

Chen, Charles D.;
Franklin, Erin E.;
Li, Yan;
Joseph-Mathurin, Nelly;
Burns, Aime L.;
Hobbs, Diana A.;
McCullough, Austin A.;
Schultz, Stephanie A.;
Xiong, Chengjie;
Wang, Guoqiao;
Masellis, Mario;
Hsiung, Ging-Yuek Robin;
Gauthier, Serge;
Berman, Sarah B.;
Roberson, Erik D.;
Honig, Lawrence S.;
Clarnette, Roger;
Ringman, John M.;
Galvin, James E.;
Brooks, William

Publication type:

Article

Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02892-5

By:

Liao, Fan;
Calvo-Rodriguez, Maria;
Chhaya, Meha;
Sefrin, Julian P;
Charych, Erik I;
Mezler, Mario;
Clausznitzer, Diana;
McGlame, Emily J;
Zhao, Karen;
Rodgers, Allison;
Cao, Yang;
Secker, Philipp F;
Fernandez Garcia-Agudo, Laura;
Huang, Lili;
Klein, Corinna;
Dellovade, Tammy;
Karran, Eric

Publication type:

Article

Multimodal neuroimaging insights into the neurobiology of healthy aging across the lifespan.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2025, v. 52, n. 7, p. 2267, doi. 10.1007/s00259-025-07100-w

By:

Knudsen, Laust Vind;
Michel, Tanja Maria;
Farahani, Ziba Ahangarani;
Vafaee, Manouchehr Seyedi

Publication type:

Article

Investigation of Fibrillar Aggregates Formed by Pathogenic Pre-pro-vasopressin Mutants that Cause ADNDI Open Access.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 6, p. 1577, doi. 10.1210/clinem/dgae749

By:

Vaizoglu, Refika Dilara;
Erdem, Beril;
Gul, Mehmet;
Acar, Ceren;
Ozdemirel, Huseyin Ozgur;
Ozer, Emel Saglar;
Mergen, Hatice

Publication type:

Article

Chronic Vanadium Exposure Promotes Aggregation of Alpha‐Synuclein, Tau and Amyloid Beta in Mouse Brain.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 5, p. 1, doi. 10.1111/jnc.70082

By:

Folarin, O. R.;
Olopade, F. E.;
Gilbert, T. T.;
Ladagu, A. D.;
Pires dos Santos, P. I.;
Mustapha, O. A.;
Kpasham, L. Z.;
Olopade, J. O.;
Outeiro, T. F.

Publication type:

Article

Cannabidiolic Acid Rescues Deficits in Hippocampal Long-Term Potentiation in Models of Alzheimer's Disease: An Electrophysiological and Proteomic Analysis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4944, doi. 10.3390/ijms26104944

By:

Gil, Beatriz;
Sullivan, Mairéad;
Scaife, Caitriona;
Glennon, Jeffrey C.;
Herron, Caroline

Publication type:

Article

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-?1?40 peptide.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 1, p. 79, doi. 10.1038/nsmb.2191

By:

Narayan, Priyanka;
Orte, Angel;
Clarke, Richard W;
Bolognesi, Benedetta;
Hook, Sharon;
Ganzinger, Kristina A;
Meehan, Sarah;
Wilson, Mark R;
Dobson, Christopher M;
Klenerman, David

Publication type:

Article

Research highlights.

Published in:: Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 747, doi. 10.1038/nsmb0711-747
Publication type:: Article

Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+].

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 598, doi. 10.1038/nsmb.1617

By:

Tessier, Peter M.;
Lindquist, Susan

Publication type:

Article

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 6, p. 558, doi. 10.1038/nsmb.1437

By:

Ehrnhoefer, Dagmar E.;
Bieschke, Jan;
Boeddrich, Annett;
Herbst, Martin;
Masino, Laura;
Lurz, Rudi;
Engemann, Sabine;
Pastore, Annalisa;
Wanker, Erich E.

Publication type:

Article

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1157, doi. 10.1038/nsmb1345

By:

Chimon, Sandra;
Shaibat, Medhat A.;
Jones, Christopher R.;
Calero, Diana C.;
Aizezi, Buzulagu;
Ishii, Yoshitaka

Publication type:

Article

A toxic monomeric conformer of the polyglutamine protein.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 4, p. 332, doi. 10.1038/nsmb1215

By:

Nagai, Yoshitaka;
Inui, Takashi;
Popiel, H. Akiko;
Fujikake, Nobuhiro;
Hasegawa, Kazuhiro;
Urade, Yoshihiro;
Goto, Yuji;
Naiki, Hironobu;
Toda, Tatsushi

Publication type:

Article

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 3, p. 195, doi. 10.1038/nsmb1058

By:

Jahn, Thomas R.;
Parker, Martin J.;
Homans, Steve W.;
Radford, Sheena E.

Publication type:

Article

Sodium-salt adduct fullerenes prevent self-association and amyloid β fibril formation: molecular dynamics approach.

Published in:

Soft Materials, 2020, v. 18, n. 2/3, p. 335, doi. 10.1080/1539445X.2020.1746336

By:

Balderas Altamirano, Miguel Angel;
Basurto-Islas, Gustavo;
Martínez-Herrera, Melchor;
Pichardo Molina, Juan Luis;
Figueroa-Gerstenmaier, Susana

Publication type:

Article

Amyloids — a functional coat for microorganisms.

Published in:

Nature Reviews Microbiology, 2005, v. 3, n. 4, p. 333, doi. 10.1038/nrmicro1127

By:

Gebbink, Martijn F. B. G.;
Claessen, Dennis;
Bouma, Barend;
Dijkhuizen, Lubbert;
Wösten, Han A. B.

Publication type:

Article

The effect of serum and follicular fluid amyloid-associated protein levels on in vitro fertilization outcome in patients with polycystic ovary syndrome.

Published in:

Journal of Assisted Reproduction & Genetics, 2015, v. 32, n. 11, p. 1637, doi. 10.1007/s10815-015-0582-3

By:

Timur, Hakan;
Yimaz, Nafiye;
Kahyaoglu, Inci;
Inal, Hasan;
Erkaya, Salim

Publication type:

Article

Development of a quantitative structure activity relations (QSAR) model to guide the design of fluorescent dyes for detecting amyloid fibrils.

Published in:

Biotechnic & Histochemistry, 2014, v. 89, n. 1, p. 1, doi. 10.3109/10520295.2013.785593

By:

Inshyn, DI;
Kovalska, VB;
Losytskyy, MY;
Slominskii, YL;
Tolmachev, OI;
Yarmoluk, SM

Publication type:

Article

Novel fluorescent trimethine cyanine dye 7519 for amyloid fibril inhibition assay.

Published in:

Biotechnic & Histochemistry, 2011, v. 86, n. 3, p. 188, doi. 10.3109/10520291003648466

By:

Volkova, KD;
Kovalska, VB;
Inshin, D;
Slominskii, YL;
Tolmachev, OI;
Yarmoluk, SM

Publication type:

Article

Inhibition of Amyloid β Aggregation and Cytotoxicity by Berbamine Hydrochloride.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 56, p. 1, doi. 10.1002/chem.202301865

By:

Dong, Li;
Xie, Huan‐Zhang;
Jia, Lee;
Hong, Liu;
Li, Gao

Publication type:

Article

Fibrils Emerging from Droplets: Molecular Guiding Principles behind Phase Transitions of a Short Peptide‐Based Condensate Studied by Solid‐State NMR**.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 50, p. 1, doi. 10.1002/chem.202301159

By:

Lipiński, Wojciech P.;
Zehnder, Johannes;
Abbas, Manzar;
Güntert, Peter;
Spruijt, Evan;
Wiegand, Thomas

Publication type:

Article

Thiophene‐Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer's Disease.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 21, p. 1, doi. 10.1002/chem.202203568

By:

Lantz, Linda;
Shirani, Hamid;
Ghetti, Bernardino;
Vidal, Ruben;
Klingstedt, Therése;
Nilsson, K. Peter R.

Publication type:

Article

Proteophenes – Amino Acid Functionalized Thiophene‐based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 62, p. 1, doi. 10.1002/chem.202201557

By:

Björk, Linnea;
Bäck, Marcus;
Lantz, Linda;
Ghetti, Bernardino;
Vidal, Ruben;
Klingstedt, Therése;
Nilsson, K. Peter R.

Publication type:

Article

Front Cover: Cucurbit[7]uril Inhibits Islet Amyloid Polypeptide Aggregation by Targeting N Terminus Hot Segments and Attenuates Cytotoxicity (Chem. Eur. J. 38/2022).

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 38, p. 1, doi. 10.1002/chem.202201697

By:

Maity, Debabrata;
Oh, Yujeong;
Gremer, Lothar;
Hoyer, Wolfgang;
Magzoub, Mazin;
Hamilton, Andrew D.

Publication type:

Article

Versatile Near‐Infrared Super‐Resolution Imaging of Amyloid Fibrils with the Fluorogenic Probe CRANAD‐2.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 19, p. 1, doi. 10.1002/chem.202200026

By:

Torra, Joaquim;
Viela, Felipe;
Megías, Diego;
Sot, Begoña;
Flors, Cristina

Publication type:

Article

Fibril Structure Demonstrates the Role of Iodine Labelling on a Pentapeptide Self‐Assembly.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 14, p. 1, doi. 10.1002/chem.202104089

By:

Marchetti, Alessandro;
Pizzi, Andrea;
Bergamaschi, Greta;
Demitri, Nicola;
Stollberg, Ulrike;
Diederichsen, Ulf;
Pigliacelli, Claudia;
Metrangolo, Pierangelo

Publication type:

Article

Cover Feature: Prebiotically Plausible Autocatalytic Peptide Amyloids (Chem. Eur. J. 3/2022).

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 3, p. 1, doi. 10.1002/chem.202104546

By:

Rout, Saroj K.;
Rhyner, David;
Riek, Roland;
Greenwald, Jason

Publication type:

Article

The Catalytic Mechanism of the Retaining Glycosyltransferase Mannosylglycerate Synthase.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 56, p. 13998, doi. 10.1002/chem.202101724

By:

Ferreira, Pedro;
Fernandes, Pedro A.;
Ramos, Maria J.

Publication type:

Article

Front Cover: Concentration‐Dependent Interactions of Amphiphilic PiB Derivative Metal Complexes with Amyloid Peptides Aβ and Amylin (Chem. Eur. J. 6/2021).

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 6, p. 1860, doi. 10.1002/chem.202004824

By:

Majdoub, Saida;
Garda, Zoltán;
Oliveira, Alexandre C.;
Relich, Inga;
Pallier, Agnès;
Lacerda, Sara;
Hureau, Christelle;
Geraldes, Carlos F. G. C.;
Morfin, Jean‐François;
Tóth, Éva

Publication type:

Article

Concentration‐Dependent Interactions of Amphiphilic PiB Derivative Metal Complexes with Amyloid Peptides Aβ and Amylin**.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 6, p. 1864, doi. 10.1002/chem.202004825

By:

Majdoub, Saida;
Garda, Zoltán;
Oliveira, Alexandre C.;
Relich, Inga;
Pallier, Agnès;
Lacerda, Sara;
Hureau, Christelle;
Geraldes, Carlos F. G. C.;
Morfin, Jean‐François;
Tóth, Éva

Publication type:

Article

Naphthoquinone–Dopamine Hybrids Inhibit α‐Synuclein Aggregation, Disrupt Preformed Fibrils, and Attenuate Aggregate‐Induced Toxicity.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 69, p. 16486, doi. 10.1002/chem.202003374

By:

Paul, Ashim;
Huber, Adi;
Rand, Daniel;
Gosselet, Fabien;
Cooper, Itzik;
Gazit, Ehud;
Segal, Daniel

Publication type:

Article

Helical γ‐Peptide Foldamers as Dual Inhibitors of Amyloid‐β Peptide and Islet Amyloid Polypeptide Oligomerization and Fibrillization.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 64, p. 14612, doi. 10.1002/chem.202001716

By:

Kaffy, Julia;
Berardet, Corentin;
Mathieu, Loïc;
Legrand, Baptiste;
Taverna, Myriam;
Halgand, Frédéric;
Van Der Rest, Guillaume;
Maillard, Ludovic T.;
Ongeri, Sandrine

Publication type:

Article

Cationic Carbosilane Dendritic Systems as Promising Anti‐Amyloid Agents in Type 2 Diabetes.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 34, p. 7609, doi. 10.1002/chem.202000091

By:

Lozano‐Cruz, Tania;
Alcarraz‐Vizán, Gema;
Mata, F. Javier;
Pablo, Sara;
Ortega, Paula;
Duarte, Yorley;
Bravo‐Moraga, Felipe;
González‐Nilo, Fernando D.;
Novials, Anna;
Gómez, Rafael

Publication type:

Article

Synthesis and Characterization of Thiophene‐based Donor–Acceptor–Donor Heptameric Ligands for Spectral Assignment of Polymorphic Amyloid‐β Deposits.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 33, p. 7425, doi. 10.1002/chem.201905612

By:

Lantz, Linda;
Shirani, Hamid;
Klingstedt, Therése;
Nilsson, K. Peter R.

Publication type:

Article

Supramolecular Regulation of Polydopamine Formation by Amyloid Fibers.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 24, p. 5500, doi. 10.1002/chem.202000437

By:

Shin, J. H.;
Le, Nghia T. K.;
Jang, Hongje;
Lee, Taehoon;
Kang, Kyungtae

Publication type:

Article

Rational Design of a Cocktail of Inhibitors against Aβ Aggregation.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 16, p. 3499, doi. 10.1002/chem.201905621

By:

Li, Gao;
Yang, Wu‐Yue;
Li, Wen‐Hao;
Luo, Yun‐Yi;
Lim, Yeh‐Jun;
Li, Yang;
Paul, Ashim;
Segal, Daniel;
Hong, Liu;
Li, Yan‐Mei

Publication type:

Article

Front Cover: The Route from the Folded to the Amyloid State: Exploring the Potential Energy Surface of a Drug‐Like Miniprotein (Chem. Eur. J. 9/2020).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 9, p. 1888, doi. 10.1002/chem.201905180

By:

Taricska, Nóra;
Horváth, Dániel;
Menyhárd, Dóra K.;
Ákontz‐Kiss, Hanna;
Noji, Masahiro;
So, Masatomo;
Goto, Yuji;
Fujiwara, Toshimichi;
Perczel, András

Publication type:

Article

The Route from the Folded to the Amyloid State: Exploring the Potential Energy Surface of a Drug‐Like Miniprotein.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 9, p. 1968, doi. 10.1002/chem.201903826

By:

Taricska, Nóra;
Horváth, Dániel;
Menyhárd, Dóra K.;
Ákontz‐Kiss, Hanna;
Noji, Masahiro;
So, Masatomo;
Goto, Yuji;
Fujiwara, Toshimichi;
Perczel, András

Publication type:

Article

Mass Determination of Entire Amyloid Fibrils by Using Mass Spectrometry.

Published in:

Angewandte Chemie, 2016, v. 128, n. 7, p. 2386, doi. 10.1002/ange.201508995

By:

Doussineau, Tristan;
Mathevon, Carole;
Altamura, Lucie;
Vendrely, Charlotte;
Dugourd, Philippe;
Forge, Vincent;
Antoine, Rodolphe

Publication type:

Article

Silica Nanowires Templated by Amyloid-like Fibrils.

Published in:

Angewandte Chemie, 2015, v. 127, n. 45, p. 13525, doi. 10.1002/ange.201508415

By:

Al‐Garawi, Zahraa S.;
Thorpe, Julian R.;
Serpell, Louise C.

Publication type:

Article

A Self-Assembled Spherical Complex Displaying a Gangliosidic Glycan Cluster Capable of Interacting with Amyloidogenic Proteins.

Published in:

Angewandte Chemie, 2015, v. 127, n. 29, p. 8555, doi. 10.1002/ange.201501981

By:

Sato, Sota;
Yoshimasa, Yutaka;
Fujita, Daishi;
Yagi ‐ Utsumi, Maho;
Yamaguchi, Takumi;
Kato, Koichi;
Fujita, Makoto

Publication type:

Article

Gallotannins and Tannic Acid: First Chemical Syntheses and In Vitro Inhibitory Activity on Alzheimer's Amyloid b-Peptide Aggregation.

Published in:

Angewandte Chemie, 2015, v. 127, n. 28, p. 8335, doi. 10.1002/ange.201411606

By:

Sylla, Tahiri;
Pouységu, Laurent;
Grégory Da Costa;
Deffieux, Denis;
Monti, Jean-Pierre;
Quideau, Stéphane

Publication type:

Article

Multi-Frequency, Multi-Technique Pulsed EPR Investigation of the Copper Binding Site of Murine Amyloid β Peptide.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1581, doi. 10.1002/ange.201410389

By:

Donghun Kim;
Jeong Kyu Bang;
Sun Hee Kim

Publication type:

Article

A Hexameric Peptide Barrel as Building Block of Amyloid-β Protofibrils.

Published in:

Angewandte Chemie, 2014, v. 126, n. 47, p. 12970, doi. 10.1002/ange.201406357

By:

Lendel, Christofer;
Bjerring, Morten;
Dubnovitsky, Anatoly;
Kelly, Robert T.;
Filippov, Andrei;
Antzutkin, Oleg N.;
Nielsen, Niels Chr.;
Härd, Torleif

Publication type:

Article

Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid β Protofibril Interactions Using 13Cmethyl-DEST and Lifetime Line Broadening.

Published in:

Angewandte Chemie, 2014, v. 126, n. 39, p. 10513, doi. 10.1002/ange.201405180

By:

Fawzi, Nicolas L.;
Libich, David S.;
Ying, Jinfa;
Tugarinov, Vitali;
Clore, G. Marius

Publication type:

Article

The Molecular Structure of Alzheimer β-Amyloid Fibrils Formed in the Presence of Phospholipid Vesicles.

Published in:

Angewandte Chemie, 2014, v. 126, n. 35, p. 9448, doi. 10.1002/ange.201311106

By:

Niu, Zheng;
Zhao, Weijing;
Zhang, Zhengfeng;
Xiao, Fanshu;
Tang, Xinqi;
Yang, Jun

Publication type:

Article

Maintenance of Amyloid β Peptide Homeostasis by Artificial Chaperones Based on Mixed-Shell Polymeric Micelles.

Published in:

Angewandte Chemie, 2014, v. 126, n. 34, p. 9131, doi. 10.1002/ange.201400735

By:

Huang, Fan;
Wang, Jianzu;
Qu, Aoting;
Shen, Liangliang;
Liu, Jinjian;
Liu, Jianfeng;
Zhang, Zhenkun;
An, Yingli;
Shi, Linqi

Publication type:

Article