Works about AMP-activated protein kinases

Results: 1686

Flavonoids of Mao Jian Green Tea Ameliorate Glycemic Metabolism in Type-2-Diabetic Rats via AMPK Signaling Pathways and Gut Microbiota Regulation.

Published in:

Foods, 2025, v. 14, n. 13, p. 2402, doi. 10.3390/foods14132402

By:

Wu, Lei;
Niu, Yao;
Liu, Fei;
Tian, Jiongling;
Ma, Zhilin;
Yang, Jiahui;
Guo, Xiaomeng;
Sun, Yaogui

Publication type:

Article

Estradiol Prevents Amyloid Beta-Induced Mitochondrial Dysfunction and Neurotoxicity in Alzheimer's Disease via AMPK-Dependent Suppression of NF-κB Signaling.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6203, doi. 10.3390/ijms26136203

By:

Mishra, Pranav;
Esfahani, Ehsan K.;
Fernyhough, Paul;
Albensi, Benedict C.

Publication type:

Article

Valproate independently activates Snf1, inhibits TORC1, and induces repression of INO1 transcription by increasing nuclear localization of Opi1.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07540-2

By:

Case, Kendall C.;
Orkun, Lara;
Greenberg, Miriam L.

Publication type:

Article

Comparative Efficacy of Cytokines and Drugs in Promoting the Expansion of Bone Marrow-Derived Mesenchymal Stem Cells: A Systematic Review and Meta-Analysis.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2025, v. 59, n. 2, p. 767, doi. 10.5530/ijper.20251689

By:

Jinhui Liu;
Sheng Liu;
Chunming Li

Publication type:

Article

Buyang Huanwu Decoction improves energy metabolism disorders after cerebral ischemia–reperfusion by regulating the SIRT1/AMPK signaling pathway to promote glycolysis and the tricarboxylic acid cycle.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01163-5

By:

Hu, Zhongji;
Deng, Nujiao;
Li, Yanling;
Bai, Yang;
Lan, Xiao;
Xiong, Tingting;
Ding, Huang;
Liu, Xiaodan;
Deng, Changqing

Publication type:

Article

Metformin as a Modulator of Autophagy and Hypoxia Responses in the Enhancement of Wound Healing in Diabetic Rats.

Published in:

Inflammation, 2025, v. 48, n. 3, p. 1391, doi. 10.1007/s10753-024-02129-9

By:

Tombulturk, Fatma Kubra;
Soydas, Tugba;
Kanigur-Sultuybek, Gönül

Publication type:

Article

A new pathway for neuroprotection against tau hyperphosphorylation via δ-opioid receptor initiated inhibition of CDK5 and AMPK signaling.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1587219

By:

Li, Jiahui;
Xu, Yuan;
Balboni, Gianfranco;
Xia, Ying

Publication type:

Article

Sestrin2 Overexpression Inhibits Proliferation and Epithelial–Mesenchymal Transition and Induces Autophagy Through the AMPK/mTOR Signaling Pathway in Human Prostate Cancer Cells.

Published in:

Prostate Cancer (20903111), 2025, v. 2025, p. 1, doi. 10.1155/proc/8842203

By:

Kim, Yae-Ji;
Lee, Hui-Ju;
Kim, Kyung-Hyun;
Hong, Geum-Lan;
Jung, Ju-Young;
Farhan, Mohd

Publication type:

Article

Modulating ovarian cancer progression through FDX1-driven autophagy.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00994-7

By:

Liu, Chang;
Wang, Siyu;
Zhao, Jiabao;
Qiu, Hui;
Du, Hongmei

Publication type:

Article

PTEN deficiency in postnatally developing Purkinje cells disrupts metabolic signaling, leading to dendritic abnormalities and sex-specific behavioral deficits.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09059-y

By:

Walsh, Lindsay J.;
Espinal-San Miguel, Izabella M.;
Rodriguez, Ana V.;
Peña, Ursula M.;
Flynn, Kiley E.;
Remillard, Will C.;
Brazier, Siena R.;
Anderson, Natalia I.;
Clark, Aidan J.;
De Varona, Tiffany A.;
Soto, Ileana

Publication type:

Article

Exploring the Chemical Diversity of Qurs-E-Ziabetus Sada: A Stride Towards Analytical and Biological Validation.

Published in:

Oriental Journal of Chemistry, 2025, v. 41, n. 2, p. 439, doi. 10.13005/ojc/410213

By:

KUMAR, AWADHESH;
VED, AKASH;
AZIZ, IRFAN;
HASAN, SYED MISBAHUL;
SONI, PUSHPENDRA;
KUSHWAHA, SHOM PRAKASH

Publication type:

Article

Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol.

Published in:

Immunity & Ageing, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12979-025-00522-y

By:

Ahmed, Mohamed

Publication type:

Article

Tumor metabolome remolded by low dose mitochondrial uncoupler elicites robust CD8<sup>+</sup> T cell response.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02584-9

By:

Jiang, Xiaoxiao;
Fan, Zhijin;
Zhang, Zhenzhen;
Zeng, Fanchu;
Sun, Tong;
Li, Yuchen;
Huang, Guojia;
Nie, Liming

Publication type:

Article

Lipid metabolites affected by deficient autophagy antagonize the occurrence of autophagy through AMPK signaling in insects.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02274-z

By:

Tian, Ling;
Zhong, Qien;
Yang, Yubei;
Wu, Wenmei;
Xiao, Yang;
Li, Sheng;
Li, Kang

Publication type:

Article

Low doses of ozone alleviate cardiomyocyte ferroptosis induced by hypoxia–reoxygenation injury via the AMPK–mTOR pathway.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02829-4

By:

Ding, Yu;
Hong, Tao

Publication type:

Article

Increased adenosine monophosphate–activated protein kinase activity in mice with physical exercise intervention: a systematic review.

Published in:

Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación, 2025, n. 68, p. 377, doi. 10.47197/retos.v68.115136

By:

Prabowo, Suryanto Agung;
Wibawa, Junian Cahyanto;
Hamdani;
Indriarsa, Nanang;
Al Ardha, Muchamad Arif;
Hidayat, Taufiq;
Subagio, Irmantara;
Barata, Iwan;
Lobo, Joseph;
Ayubi, Novadri

Publication type:

Article

Naringenin attenuates slow-transit constipation by regulating the AMPK/mTOR/ULK1 signalling pathway: in vivo and in vitro studies.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1550458

By:

Wang, Yahui;
Wang, Xiaopeng;
Qian, Yifei;
Sun, Mingming;
Yang, Huiju;
Su, Lianlin;
Yan, Shuai

Publication type:

Article

Antrodia cinnamomea Extract Attenuates Obesity by Targeting Adipogenic Pathways and Gut Dysbiosis in High-Fat Diet-Fed Mice.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5856, doi. 10.3390/ijms26125856

By:

Lin, Kuen-Tze;
Lee, Shih-Yu;
Ya-Jy, Lee;
Wu, Po-Jui;
Chang, Tsu-Chung;
Chang, Wen-Liang;
Yen, I-Chuan

Publication type:

Article

Enhancing Skeletal Muscle Fiber Type Transition Through Substrate Coating Alteration in Myoblast Cell Culture.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5637, doi. 10.3390/ijms26125637

By:

Riskawati, Yhusi Karina;
Lin, Chuang-Yu;
Niwa, Akira;
Chang, Hsi

Publication type:

Article

Correction: Wang et al. Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling. Molecules 2019, 24 , 3319.

Published in:

2025

By:

Wang, Xueliang;
Shan, Xindi;
Dun, Yunlou;
Cai, Chao;
Hao, Jiejie;
Li, Guoyun;
Cui, Kaiyun;
Yu, Guangli

Publication type:

Correction Notice

Therapeutic Potential of Ginsenosides in Anthracycline-Induced Cardiotoxicity.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2527, doi. 10.3390/molecules30122527

By:

Bai, Rongrong;
Zhao, Zhigao;
Han, Xing;
Shang, Mingying;
Liu, Guangxue;
Xu, Feng;
Cai, Shaoqing

Publication type:

Article

A mixture of ginger phenolic compounds enhances mitochondrial function, activates AMPK, and reduces lipid accumulation in adipocytes.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326690

By:

Preciado-Ortiz, María Elizabeth;
Pérez-Jiménez, Berenice;
Barrera-Gómez, Paulina;
Rivera-Valdés, Juan José;
Acevedo-Carabantes, Joshua Ayork;
Vásquez-Reyes, Sarai;
Tovar, Armando R.;
Torres, Nimbe;
Torre-Villalvazo, Ivan;
Martínez-López, Erika

Publication type:

Article

Unraveling the Mechanisms of Active Saponins from Rhizoma Anemarrhenae Against Ferroptosis in Alzheimer's Disease: Integrating Network Pharmacology, Cell Membrane Chromatography, and Experimental Validation.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 4, p. 1119, doi. 10.1142/S0192415X25500429

By:

Peng, Jing;
Lu, Zhongjiao;
Sai, Fangfang;
Min, Liang;
Zhang, Xu;
Ru, Dan;
Song, Yaying;
Wei, Xin;
Gao, Li;
Wang, Hai-Qiao

Publication type:

Article

Caloric Restriction Mimetics: A comparative analysis of natural and synthetic agents in autophagy modulation.

Published in:

Ars Pharmaceutica, 2025, v. 66, n. 3, p. 385, doi. 10.30827/ars.v66i3.32081

By:

Fernando Murillo-Cancho, Antonio;
José Nievas-Soriano, Bruno;
Lozano-Paniagua, David

Publication type:

Article

Antioxidant Peptides Derived from Woody Oil Resources: Mechanisms of Redox Protection and Emerging Therapeutic Opportunities.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 842, doi. 10.3390/ph18060842

By:

Tu, Jia;
Peng, Jie;
Wen, Li;
Li, Changzhu;
Xiao, Zhihong;
Wu, Ying;
Xu, Zhou;
Hu, Yuxi;
Zhong, Yan;
Miao, Yongjun;
Xiao, Jingjing;
Liu, Sisi

Publication type:

Article

Synergistic Autophagy-Related Mechanisms of Protection Against Brain Aging and AD: Cellular Pathways and Therapeutic Strategies.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 829, doi. 10.3390/ph18060829

By:

Cordos, Bogdan;
Tero-Vescan, Amelia;
Hampson, Ian N.;
Oliver, Anthony W.;
Slevin, Mark

Publication type:

Article

Gryllus bimaculatus Hydrolysate Ameliorates Obesity-Induced Muscle Atrophy by Activating Skeletal Muscle AMPK in Mice.

Published in:

Nutrients, 2025, v. 17, n. 12, p. 1990, doi. 10.3390/nu17121990

By:

Park, Kyungeun;
Jung, Sunyoon;
Li, Chunmei;
Ha, Jung-Heun;
Jeong, Yoonhwa

Publication type:

Article

ZC3H13‐induced the m6A modification of hsa_circ_0081723 promotes cervical cancer progression via AMPK/p53 pathway.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 12, p. 2286, doi. 10.1111/jog.16140

By:

Wei, Qiong;
Yang, Yi;
Li, Chun;
Wang, Huimin

Publication type:

Article

Cyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00642-5

By:

Du, Yi-Wei;
Li, Xiao-Kang;
Wang, Ting-Ting;
Zhou, Lu;
Li, Hui-Rong;
Feng, Lan;
Ma, Heng;
Liu, Hong-Bao

Publication type:

Article

Improvement of ACK1-targeted therapy efficacy in lung adenocarcinoma using chloroquine or bafilomycin A1.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00602-z

By:

Zhu, Jinhong;
Cao, Kui;
Zhao, Meng;
Ma, Keru;
Jiang, Xiangyu;
Bai, Yuwen;
Ling, Xiaodong;
Ma, Jianqun

Publication type:

Article

SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways.

Published in:

Molecular Medicine, 2022, v. 28, p. 1, doi. 10.1186/s10020-022-00554-w

By:

Zhuang, Xiaonan;
Ma, Jun;
Xu, Gezhi;
Sun, Zhongcui

Publication type:

Article

Trigonelline Chloride Ameliorated Triphenyltin-Induced Testicular Autophagy, Inflammation, and Apoptosis: Role of Recovery.

Published in:

Microscopy & Microanalysis, 2024, v. 30, n. 1, p. 133, doi. 10.1093/micmic/ozad137

By:

Elsheikh, Arwa A;
Shalaby, Amany Mohamed;
Alabiad, Mohamed Ali;
Abd-Almotaleb, Noha Ali;
Alorini, Mohammed;
Alnasser, Sulaiman Mohammed;
Elhasadi, Ibtesam;
El-Nagdy, Samah A

Publication type:

Article

β‐Sitosterol Ameliorates Ulcerative Colitis Through Modulation of the AMPK/MLCK Anti‐Inflammatory Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 6, p. 1, doi. 10.1002/jbt.70287

By:

Zhang, Yuansen;
Jin, Xiaosheng;
Xia, Huanhuan;
Wu, Xiaoqiu;
Chen, Wenjun;
Zhuang, Mengxiao;
Tang, Sensen

Publication type:

Article

Salvianolic Acid A Attenuates Lipopolysaccharide‐Induced Acute Lung Injury by Activating AMPK/SIRT1/Nrf2 Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 5, p. 1, doi. 10.1002/jbt.70282

By:

Wang, Pengwei;
Sun, Yu;
Zhang, Ru;
Guo, Yongli;
Zhang, Yongheng;
Guo, Shengjie;
Wang, Yemin;
Gao, Jianlian;
Yang, Pengfei;
Deng, Zhijian

Publication type:

Article

Modulation of AMPK/mTOR Autophagic Pathway Using Dapagliflozin Protects Against Cadmium‐Induced Testicular and Renal Injury in Rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 4, p. 1, doi. 10.1002/jbt.70257

By:

Dagher, Doha M.;
Zaghloul, Marwa S.;
Suddek, Ghada M.

Publication type:

Article

Promotion of Autophagy and Apoptosis in Colorectal Cancer Exposed to Imatinib and Thymoquinone.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 4, p. 1, doi. 10.1002/jbt.70238

By:

El‐Khouly, Dalia;
Thabet, Nadia A.;
Sayed‐Ahmed, Mohamed;
Omran, Mervat M.

Publication type:

Article

Borneol Ameliorates Non‐Alcoholic Fatty Liver Disease via Promoting AMPK‐Mediated Lipophagy.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 2, p. 1, doi. 10.1002/jbt.70182

By:

Sriramdasu, Shalemraju;
Sharma, Shivam;
Ansari, Abid Reza;
Phatak, Nikhil Vinayak;
Tikoo, Kulbhushan

Publication type:

Article

Protective Role of Oxycodone in Myocardial Oxidative Stress and Mitochondrial Dysfunction Induced by Ischemia‐Reperfusion.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 2, p. 1, doi. 10.1002/jbt.70151

By:

Jiang, Yongzheng;
He, Hua;
Jia, Xinwei

Publication type:

Article

Dexmedetomidine Regulates Macrophage Phenotype Remodeling Through AMPK/SIRT1 to Alleviate Inflammatory Mediators and Lung Injury.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70108

By:

Zhao, Yi‐si;
Shi, Ya‐kang;
Li, Ke‐feng;
Ma, Bei;
Lin, Shi‐hui;
Xing, Yu;
Xu, Fang

Publication type:

Article

l‐Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 3, p. 1, doi. 10.1002/jbt.23663

By:

Pal, Swagata;
Kabeer, Shaheen Wasil;
Sharma, Shivam;
Tikoo, Kulbhushan

Publication type:

Article

Asperuloside alleviates cyclophosphamide‐induced myelosuppression by promoting AMPK/mTOR pathway‐mediated autophagy.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 2, p. 1, doi. 10.1002/jbt.23641

By:

Che, Hong;
Li, Linlin;
Zhao, Bingjie;
Hu, Lian;
Xiao, Li;
Liu, Peijia;
Liu, Songshan;
Hou, Zhufa

Publication type:

Article

Isoquercitrin promotes ferroptosis and oxidative stress in nasopharyngeal carcinoma via the AMPK/NF‐κB pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23542

By:

Luo, Xinggu;
Gong, Yongqian;
Jiang, Qingshan;
Wang, Qin;
Li, Songtao;
Liu, Lijun

Publication type:

Article

Sesamol attenuates bleomycin‐induced pulmonary toxicity and fibrosis in experimental animals.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 11, p. 1, doi. 10.1002/jbt.23472

By:

Kaushik, Swati;
Bhargava, Poorva;
Sharma, Jatin;
Arava, Sudheer;
Nag, Tapas C.;
Arya, Dharamvir S.;
Bhatia, Jagriti

Publication type:

Article

Gentiopicroside enhances the protective effect of trimetazidine against myocardial ischemia‐reperfusion injury via the AMPK/NLRP3 inflammasome signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 7, p. 1, doi. 10.1002/jbt.23366

By:

Wang, Yu;
Sheng, Yao;
Ji, Ningning;
Zhang, Hui

Publication type:

Article

Inhibiting AKT signaling pathway with cilostazol and meloxicam synergism for suppressing K562 cells in vitro.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 11, p. 1, doi. 10.1002/jbt.23185

By:

Naderbar, Laya;
Pazhang, Yaghub;
Rezaie, Jafar

Publication type:

Article

Bergapten mediated inflammatory and apoptosis through AMPK/eNOS/AKT signaling pathway of isoproterenol‐induced myocardial infarction in Wistar rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 9, p. 1, doi. 10.1002/jbt.23143

By:

Yang, Yanni;
Han, Juanping;
Lilly, Renju G.;
Yang, Qin;
Guo, Yanjie

Publication type:

Article

MTX-induced gastrointestinal reactions in RA: Prevotella enrichment, gut dysbiosis, and PI3K/Akt/Ras/AMPK pathways.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 6, p. 2163, doi. 10.1007/s10067-025-07406-y

By:

Duo, Ruixue;
Wang, Yining;
Ma, Quanzhi;
Wang, Xiaoyuan;
Zhang, Yan;
Shen, Haili

Publication type:

Article

The regulatory effect of intermittent fasting on inflammasome activation in health and disease.

Published in:

Nutrition Reviews, 2024, v. 82, n. 7, p. 978, doi. 10.1093/nutrit/nuad104

By:

Wang, Chenchen;
Liu, Zhiqin;
Cai, Jinpeng;
Xu, Xi

Publication type:

Article

Sleep deprivation stimulates adaptive thermogenesis by activating AMPK pathway in mice.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2025, v. 195, n. 1, p. 141, doi. 10.1007/s00360-024-01590-0

By:

Zheng, Tian-Shu;
Gao, Xin-Ran;
Xu, Rui-Ping;
Zhao, Yi-Fei;
Yang, Zhi-Teng;
Wang, De-Hua

Publication type:

Article

Metformin's therapeutic potential in spinal cord injury: a systematic review and meta-analysis on locomotor recovery, neuropathic pain alleviation, and modulation of secondary injury mechanisms.

Published in:

Acta Neurochirurgica, 2025, v. 167, n. 1, p. 1, doi. 10.1007/s00701-025-06487-7

By:

Vazirizadeh-Mahabadi, Mohammadhossein;
Azimi, Amir;
Yarahmadi, Mobina;
Zarei, Hamed;
Tahmasbi, Fateme;
Zarrin, Amirali;
Yousefifard, Mahmoud;
Rahimi-Movaghar, Vafa

Publication type:

Article