Works matching DE "ALZHEIMER'S disease"

Results: 5000

Use of Model‐Based Meta‐Analysis to Inform the Design of Early Clinical Trials of Anti‐Amyloid Beta Therapies in Alzheimer's Disease.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 7, p. 1191, doi. 10.1002/psp4.70038

By:

Bachhav, Sagar S.;
Ponce‐Bobadilla, Ana Victoria;
Clausznitzer, Diana;
Stodtmann, Sven;
Xiong, Hao

Publication type:

Article

Interactions of Therapeutic Antibodies With Presynaptically‐Released Misfolded Proteins in Neurodegenerative Diseases. A Spatial Monte‐Carlo Simulation Study.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 7, p. 1168, doi. 10.1002/psp4.70035

By:

Goff, Jamie;
Khalifa, Maryam;
Short, Shaina M.;
van der Graaf, Piet H.;
Geerts, Hugo

Publication type:

Article

Integrative approaches in Alzheimer's disease: evaluating the potential of traditional, complementary, and integrative medicine (TCIM).

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1561702

By:

Sneha Sri, R.;
Pavithra, T.;
Vinciya, T.;
Santhosh Kumar, V.;
Harikrishnan, N.;
Begum, Rukaiah Fatma;
Ankul Singh, S.

Publication type:

Article

New approach to specific Alzheimer's disease diagnosis based on plasma biomarkers in a cognitive disorder cohort.

Published in:

European Journal of Clinical Investigation, 2025, v. 55, n. 8, p. 1, doi. 10.1111/eci.70034

By:

Álvarez‐Sánchez, Lourdes;
Ferré‐González, Laura;
Peña‐Bautista, Carmen;
Balaguer, Ángel;
Amengual, Julián Luis;
Baquero, Miguel;
Cubas, Laura;
Casanova, Bonaventura;
Cháfer‐Pericás, Consuelo

Publication type:

Article

How Can Animal Models Advance Research into High Frequency Oscillations: Guidelines for Recording, Detection and Analysis.

Published in:

Epilepsy Currents, 2025, v. 25, n. 4, p. 286, doi. 10.1177/15357597251336792

By:

Lisgaras, Christos Panagiotis;
Staba, Richard J.;
de la Prida, Liset M.

Publication type:

Article

A combined naturalistic driving, clinical, and neurobehavioral data set for investigating aging and dementia.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05554-z

By:

Blake, Matthew;
Brown, David C.;
Chen, Chen;
Al-Hammadi, Noor;
Casanova, Ramon;
Zhu, Yiqi;
Babulal, Ganesh M.

Publication type:

Article

Cortical microstructural abnormalities in dementia with Lewy bodies and their associations with Alzheimer's disease copathologies.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00944-x

By:

Mak, Elijah;
Reid, Robert I.;
Przybelski, Scott A.;
Fought, Angela J.;
Lesnick, Timothy G.;
Schwarz, Christopher G.;
Senjem, Matthew L.;
Raghavan, Sheelakumari;
Vemuri, Prashanthi;
Jack Jr, Clifford R.;
Min, Hoon Ki;
Jain, Manoj K.;
Miyagawa, Toji;
Forsberg, Leah K.;
Fields, Julie A.;
Savica, Rodolfo;
Graff-Radford, Jonathan;
Jones, David T.;
Botha, Hugo;
St. Louis, Erik K.

Publication type:

Article

Reviews.

Published in:: Chemistry & Industry, 2025, v. 89, n. 7/8, p. 30, doi. 10.1002/cind.10462
Publication type:: Article

3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation.

Published in:

Nutrition & Metabolism, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12986-025-00960-x

By:

Hu, Xiaoling;
Lin, Yu;
Huang, Kaiwen;
Xu, HuiLin;
Fu, Changmei Huang;
Ou, Jiayin;
Fan, Xiude;
Li, Zhe;
Fang, Jiansong;
Fang, Shuhuan

Publication type:

Article

Enhancing the Accuracy of Image Classification for Degenerative Brain Diseases with CNN Ensemble Models Using Mel-Spectrograms.

Published in:

Mathematics (2227-7390), 2025, v. 13, n. 13, p. 2100, doi. 10.3390/math13132100

By:

Sung, Sang-Ha;
Pokojovy, Michael;
Kang, Do-Young;
Bae, Woo-Yong;
Hong, Yeon-Jae;
Kim, Sangjin

Publication type:

Article

Multi-Task Encoder Using Peripheral Blood DNA Methylation Data for Alzheimer's Disease Prediction.

Published in:

Electronics (2079-9292), 2025, v. 14, n. 13, p. 2655, doi. 10.3390/electronics14132655

By:

Yu, Xia;
Long, Haixia;
Zeng, Rao;
Zhang, Guoqiang

Publication type:

Article

Machine Learning in Primary Health Care: The Research Landscape.

Published in:

Healthcare (2227-9032), 2025, v. 13, n. 13, p. 1629, doi. 10.3390/healthcare13131629

By:

Završnik, Jernej;
Kokol, Peter;
Žlahtič, Bojan;
Blažun Vošner, Helena

Publication type:

Article

Antioxidant, Anti-Inflammatory, and Antiapoptotic Effects of Euterpe oleracea Mart. (Açaí) in Improving Cognition Deficits: Potential Therapeutic Implications for Alzheimer's Disease.

Published in:

Plants (2223-7747), 2025, v. 14, n. 13, p. 2010, doi. 10.3390/plants14132010

By:

Ferreira, Flávia dos Santos;
de Mattos, Juliana Lucena Azevedo;
da Silva, Paula Hosana Fernandes;
da Costa, Cristiane Aguiar;
Ognibene, Dayane Teixeira;
Resende, Angela de Castro;
de Bem, Graziele Freitas

Publication type:

Article

Nutraceutical Strategies for Targeting Mitochondrial Dysfunction in Neurodegenerative Diseases.

Published in:

Foods, 2025, v. 14, n. 13, p. 2193, doi. 10.3390/foods14132193

By:

Davì, Federica;
Iaconis, Antonella;
Cordaro, Marika;
Di Paola, Rosanna;
Fusco, Roberta

Publication type:

Article

Erythrocyte Load in Cerebrospinal Fluid Linked with Hippocampal Atrophy in Alzheimer's Disease.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4670, doi. 10.3390/jcm14134670

By:

Christodoulou, Rafail;
Vamvouras, Georgios;
Lorentzen, Laura;
Vassiliou, Evros

Publication type:

Article

Diagnostic Utility of Vestibular Markers in Identifying Mild Cognitive Impairment and Early Alzheimer's Disease in Older Adults.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 13, p. 4544, doi. 10.3390/jcm14134544

By:

Alahmari, Khalid A.;
Alshehri, Sarah

Publication type:

Article

Age-sex differences in Alzheimer's and related dementias burden and risk factors in east and Southeast Asia: results from the 2021 GBD study.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1562148

By:

Zhao, Tengyu;
Pan, Pengyu;
Zhou, Yuhan;
Zhang, Xinyue;
Li, Quan;
Zhou, Yanyan

Publication type:

Article

The Role of Magnesium in Depression, Migraine, Alzheimer's Disease, and Cognitive Health: A Comprehensive Review.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2216, doi. 10.3390/nu17132216

By:

Varga, Péter;
Lehoczki, Andrea;
Fekete, Mónika;
Jarecsny, Tamás;
Kryczyk-Poprawa, Agata;
Zábó, Virág;
Major, Dávid;
Fazekas-Pongor, Vince;
Csípő, Tamás;
Varga, János Tamás

Publication type:

Article

Foeniculum vulgare Mill. Mitigates Scopolamine-Induced Cognitive Deficits via Antioxidant and Neuroprotective Mechanisms in Zebrafish.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2858, doi. 10.3390/molecules30132858

By:

Brinza, Ion;
Boiangiu, Razvan Stefan;
Todirascu-Ciornea, Elena;
Hritcu, Lucian;
Dumitru, Gabriela

Publication type:

Article

Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1- b ]Quinazolin-9(1 H)-ones as Cholinesterase Inhibitors Targeting Alzheimer's Disease Through Suzuki–Miyaura Cross-Coupling Reaction.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2791, doi. 10.3390/molecules30132791

By:

Turgunov, Davron;
Nie, Lifei;
Nasrullaev, Azizbek;
Murtazaeva, Zarifa;
Wang, Bianlin;
Kholmurodova, Dilafruz;
Kuryazov, Rustamkhon;
Zhao, Jiangyu;
Bozorov, Khurshed;
Aisa, Haji Akber

Publication type:

Article

Anti-Amyloid Aggregation Effects of Gobaishi (Galla chinensis) and Its Active Constituents.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2720, doi. 10.3390/molecules30132720

By:

Akter, Sharmin;
Tohge, Takayuki;
Ananda, Sahithya Hulimane;
Kuragano, Masahiro;
Tokuraku, Kiyotaka;
Uwai, Koji

Publication type:

Article

Chemical Composition, Acetylcholinesterase-Inhibitory Potential and Antioxidant Activity of Essential Oils from Three Populations of Parthenium hysterophorus L. in Ecuador.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2712, doi. 10.3390/molecules30132712

By:

Calva, James;
Cuenca, María Belén;
León, Andrea;
Benítez, Ángel

Publication type:

Article

Systematic Investigations of the Huperzine A—Producing Endophytic Fungi of Huperzia serrata in China and Fermentation Optimization Using OSMAC Strategy.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2704, doi. 10.3390/molecules30132704

By:

Li, Wei;
Wang, Zhicheng;
Zhu, Qiuyu;
Tian, Pingfang

Publication type:

Article

PEMFs Restore Mitochondrial and CREB/BDNF Signaling in Oxidatively Stressed PC12 Cells Targeting Neurodegeneration.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6495, doi. 10.3390/ijms26136495

By:

Merighi, Stefania;
Fernandez, Mercedes;
Nigro, Manuela;
Travagli, Alessia;
Caldon, Filippo;
Salati, Simona;
Borea, Pier Andrea;
Cadossi, Ruggero;
Varani, Katia;
Gessi, Stefania

Publication type:

Article

Soil to Synapse: Molecular Insights into the Neurotoxicity of Common Gardening Chemicals in Alzheimer's and Parkinson's Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6468, doi. 10.3390/ijms26136468

By:

Sharma, Niti;
An, Seong Soo A.

Publication type:

Article

Rhein Inhibits Microglia-Mediated Neuroinflammation and Neuronal Damage of Alzheimer's Disease via Regulating the Glutamine–Aspartate–Arginine–NO Metabolic Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6404, doi. 10.3390/ijms26136404

By:

Chi, Bingqing;
Zhang, Zhengyi;
Zhang, Zhixin;
Zhang, Han;
Tian, Mengjun;
Wang, Ying;
Gao, Xiaoyan

Publication type:

Article

RETRACTED: Maiti et al. Ameliorative Properties of Boronic Compounds in In Vitro and In Vivo Models of Alzheimer's Disease. Int. J. Mol. Sci. 2020, 21 , 6664.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6396, doi. 10.3390/ijms26136396

By:

Maiti, Panchanan;
Manna, Jayeeta;
Burch, Zoe N.;
Flaherty, Denise B.;
Larkin, Joseph D.;
Dunbar, Gary L.

Publication type:

Article

Pharmacological Evaluation of a Traditional Thai Polyherbal Formula for Alzheimer's Disease: Evidence from In Vitro and In Silico Studies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6287, doi. 10.3390/ijms26136287

By:

Waiwut, Pornthip;
Takomthong, Pitchayakarn;
Anorach, Rutchayaporn;
Lomaboot, Nattareeyada;
Daodee, Supawadee;
Chulikhit, Yaowared;
Monthakantirat, Orawan;
Khamphukdee, Charinya;
Boonyarat, Chantana

Publication type:

Article

Recent Advances in Antibody Therapy for Alzheimer's Disease: Focus on Bispecific Antibodies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6271, doi. 10.3390/ijms26136271

By:

Yang, Han-Mo

Publication type:

Article

The Inflammatory Nexus: Unraveling Shared Pathways and Promising Treatments in Alzheimer's Disease and Schizophrenia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6237, doi. 10.3390/ijms26136237

By:

Russo, Aurelio Pio;
Pastorello, Ylenia;
Dénes, Lóránd;
Brînzaniuc, Klara;
Krupinski, Jerzy;
Slevin, Mark

Publication type:

Article

Estradiol Prevents Amyloid Beta-Induced Mitochondrial Dysfunction and Neurotoxicity in Alzheimer's Disease via AMPK-Dependent Suppression of NF-κB Signaling.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6203, doi. 10.3390/ijms26136203

By:

Mishra, Pranav;
Esfahani, Ehsan K.;
Fernyhough, Paul;
Albensi, Benedict C.

Publication type:

Article

Hippocampal Neurogenesis in Alzheimer's Disease: Multimodal Therapeutics and the Neurogenic Impairment Index Framework.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6105, doi. 10.3390/ijms26136105

By:

Ma, Li;
Wei, Qian;
Jiang, Ming;
Wu, Yanyan;
Liu, Xia;
Yang, Qinghu;
Bai, Zhantao;
Yang, Liang

Publication type:

Article

A Module-Level Polygenic Risk Score-Based NetWAS Framework for Identifying AD Genetic Modules Mediated by Amygdala: An ADNI Study.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6060, doi. 10.3390/ijms26136060

By:

Luo, Haoran;
Fan, Shaoheng;
Liu, Hongwei;
Li, Wei;
Fan, Zhoujie;
Zhu, Xuancheng;
Zhang, Chen Jason;
Liang, Hong;
Cong, Shan;
Yao, Xiaohui

Publication type:

Article

Neuroprotective Mechanisms of Porcine Brain Enzyme Hydrolysate in Memory Impairment: Multi-Target Strategy Against Amyloid-β-Induced Neurotoxicity.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6030, doi. 10.3390/ijms26136030

By:

Yoon, Sun Myung;
Lee, Ye-Won;
Kim, Min Ju;
Shin, Jae-Joon;
Bae, Gun Won;
Park, Sunmin

Publication type:

Article

The Role of S6K1 in Aging and Alzheimer's Disease: Mechanistic Insights and Therapeutic Potential.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 5923, doi. 10.3390/ijms26135923

By:

Oddo, Salvatore;
Lanza, Marika;
Casili, Giovanna;
Caccamo, Antonella

Publication type:

Article

Highlights of 2024: Beyond lipids: immune dysfunction in APOE4‐associated Alzheimer's disease.

Published in:

Immunology & Cell Biology, 2025, v. 103, n. 6, p. 509, doi. 10.1111/imcb.70025

By:

McEwan, Isabella;
Thomson, Shannon;
Issar, Jasmeen K;
Finney, Caitlin A

Publication type:

Article

The dynamics of oxygenation to Aβ fibrils using an azobenzene–boron complex type photocatalyst and light energy.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10880-8

By:

Kawai, Yuichi;
Kuriyama, Mai;
Sohma, Youhei;
Kanai, Motomu;
Hori, Yukiko;
Tomita, Taisuke

Publication type:

Article

Bridging traditional Chinese medicine and Alzheimer's disease: the pivotal role of gut microbiota in multitarget therapeutic mechanisms.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1630205

By:

Wu, Weidong;
Meng, Tianwei;
Han, Lichao;
Jin, Fangfang;
Han, Pengfei;
Zhou, Yanyan

Publication type:

Article

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1606146

By:

Bi, Shijun;
Liu, Shibing;
Zhu, Kunyuan;
Gao, Dandan;
Chen, Ligang;
Yu, Chunyong;
Liang, Guobiao

Publication type:

Article

AuNP/Magnetic Bead-Enhanced Electrochemical Sensor Toward Dual Saliva Alzheimer's Biomarkers Detection.

Published in:

Sensors (14248220), 2025, v. 25, n. 13, p. 4088, doi. 10.3390/s25134088

By:

Zhao, Pengcheng;
Wang, Jieyu;
Mao, Hongju;
Zhou, Lin;
Wu, Zhenhua;
Lu, Yunxing;
Sun, Teng;
Hui, Jianan;
Ma, Guowu

Publication type:

Article

SIGNIFICADO QUE LE OTORGA EL FAMILIAR A LOS VALORES QUE INTERVIENEN EN EL CUIDADO DEL ADULTO MAYOR CON ALZHEIMER.

Published in:

Enfermería Investiga: Investigaciin, Vinculación, Docencia y Gestiin, 2025, v. 10, n. 2, p. 32, doi. 10.31243/ei.uta.v10i2.2850.2025

By:

Garcia C, Yuraima;
Evies, Aní

Publication type:

Article

Huperzia javanica as a Novel Source of Huperzine Alkaloids and Huperzine-producing Fungi.

Published in:

Indian Journal of Microbiology, 2025, v. 65, n. 2, p. 1201, doi. 10.1007/s12088-024-01361-z

By:

Le, Thanh Thi Minh;
Pham, Ha Thanh;
Trinh, Ha Thi Thu;
Quach, Ngoc Tung;
Do, Tuyen Thi;
Phi, Quyet-Tien;
Chu, Ha Hoang

Publication type:

Article

Supporting your patients.

Published in:

Dental Nursing, 2025, v. 21, n. 7, p. 338, doi. 10.12968/denn.2025.21.7.338

By:

Sinclair-Brown, Jenny

Publication type:

Article

Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00867-4

By:

Noh, Min-Young;
Kwon, Hyuk Sung;
Kwon, Min-Soo;
Nahm, Minyeop;
Jin, Hee Kyung;
Bae, Jae-sung;
Kim, Seung Hyun

Publication type:

Article

Gut microbiota-driven neuroinflammation in Alzheimer's disease: from mechanisms to therapeutic opportunities.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1582119

By:

Lei, Wenhui;
Cheng, Yiwen;
Liu, Xia;
Gao, Jie;
Zhu, Zhangcheng;
Ding, Wenwen;
Xu, Xiaocui;
Li, Yating;
Ling, Zongxin;
Jiang, Ruilai;
Chen, Xiaoying

Publication type:

Article

Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer's disease.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572468

By:

Noor, Fatima;
Aslam, Sidra;
Piras, Ignazio S.;
Tremblay, Cecilia;
Beach, Thomas G.;
Serrano, Geidy E.

Publication type:

Article

Validation of dementia-free status in the iranian brain imaging database using ADNI data: a transition point from middle age to older adulthood.

Published in:

BMC Neurology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12883-025-04293-3

By:

Ghaderi, Sadegh;
Mohammadi, Sana;
Fatehi, Farzad;
Sisakhti, Minoo;
Batouli, Seyed Amir Hossein

Publication type:

Article

Selective TRPC6 Modulator, C20, Improves Cognitive but Not Motor Function in a 5xFAD Mouse Model of Alzheimer's Disease.

Published in:

Journal of Evolutionary Biochemistry & Physiology, 2025, v. 61, n. 3, p. 926, doi. 10.1134/S0022093025030196

By:

Zernov, N.;
Меlenteva, D. M.;
Popugaeva, Е. А.

Publication type:

Article

P.006 Cost-effectiveness of Lecanemab for the treatment of early Alzheimer's Disease: a Canadian societal perspective.

Published in:

2025

By:

Burn, O;
Trueman, D;
Molloy, K;
Haynes, AE;
Castellano, K;
Pastor, L;
Wong, E;
Rothwell, S;
Jang, S;
Bodnar, C

Publication type:

Abstract

P.005 Real-world evidence of Lecanemab use in the United Statese.

Published in:

2025

By:

Zhao, C;
Brixner, DI;
Nair, KV;
Toyosaki, H;
Frech, FH;
Rosenbloom, MH

Publication type:

Abstract