Works matching DE "ALTERNATIVE RNA splicing"

Results: 2534

Determination of trunk neural crest cell fate and susceptibility to splicing perturbation by the DLC1-SF3B1-PHF5A splicing complex.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-62003-6

By:

Zheng, Zhengfan;
Guo, Suisui;
Tam, Hoi Yau;
Wang, Jingkai;
Rao, Yanxia;
Hui, Man-Ning;
Cheung, May Pui Lai;
Leung, Alan Wai Lun;
Wong, Kelvin K. W.;
Sharma, Rakesh;
Liu, Jessica Aijia;
Cheung, Martin

Publication type:

Article

Single cell and spatial alternative splicing analysis with Nanopore long read sequencing.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60902-2

By:

Fu, Yuntian;
Kim, Heonseok;
Roy, Sharmili;
Huang, Sijia;
Adams, Jenea I.;
Grimes, Susan M.;
Lau, Billy T.;
Sathe, Anuja;
Ji, Hanlee P.;
Zhang, Nancy R.

Publication type:

Article

Tensor decomposition of multi-dimensional splicing events across multiple tissues to identify splicing-mediated risk genes associated with complex traits.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.pcbi.1013303

By:

Yan, Yan;
Chen, Rui;
Kang, Hakmook;
Tan, Yuting;
Tiwari, Anshul;
Ma, Siyuan;
Wen, Zhexing;
Zhong, Xue;
Li, Bingshan

Publication type:

Article

Arabidopsis PRMT5 buffers pre‐mRNA splicing and development against genetic variation in donor splice sites.

Published in:

New Phytologist, 2025, v. 247, n. 4, p. 1727, doi. 10.1111/nph.70293

By:

Beckel, Maximiliano S.;
San Martín, Abril;
Sánchez, Sabrina E.;
Seymour, Danelle K.;
de Leone, María José;
Careno, Daniel A.;
Mora‐García, Santiago;
Weigel, Detlef;
Yanovsky, Marcelo J.;
Chernomoretz, Ariel

Publication type:

Article

Long-read RNA sequencing unveils a novel cryptic exon in MNAT1 along with its full-length transcript structure in TDP-43 proteinopathy.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08463-4

By:

Tanaka, Yoshihisa;
Sunamura, Naohiro;
Kajitani, Rei;
Ikeguchi, Marie;
Kunimoto, Ryo

Publication type:

Article

Utilizing genomics to identify novel immunotherapeutic targets in multiple myeloma high-risk subgroups.

Published in:

Genome Medicine, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13073-025-01503-y

By:

Liu, Enze;
Jaouadi, Oumaima;
Sharma, Riya;
Becker, Nathan;
Johnson, Travis S.;
Sudha, Parvathi;
Chopra, Vivek S.;
Zafar, Faiza;
Hamidi, Habib;
Pawlyn, Charlotte;
Suvannasankha, Attaya;
Abonour, Rafat;
Walker, Brian A.

Publication type:

Article

Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases.

Published in:

Annals of Clinical & Translational Neurology, 2025, v. 12, n. 7, p. 1465, doi. 10.1002/acn3.70078

By:

Segarra‐Casas, Alba;
Domínguez‐González, Cristina;
Natera‐de Benito, Daniel;
Kapetanovic, Solange;
Hernández‐Laín, Aurelio;
Estévez‐Arias, Berta;
Llansó, Laura;
Ortez, Carlos;
Jou, Cristina;
Martí‐Carrera, Itxaso;
López‐Márquez, Arístides;
Rodríguez, Maria José;
González‐Mera, Laura;
Nedkova, Velina;
Fernández‐Torrón, Roberto;
Rodríguez‐Santiago, Benjamín;
Jimenez‐Mallebrera, Cecília;
Juntas‐Morales, Raul;
López‐de Munain, Adolfo;
Surrallés, Jordi

Publication type:

Article

SK4 potentially modulates the alternative splicing profile associated with papillary thyroid cancer development in BHT101 cells.

Published in:

PeerJ, 2025, p. 1, doi. 10.7717/peerj.19391

By:

Wupuer, Alimujiang;
Kuerban, Xuekelaiti;
Ye, Gong

Publication type:

Article

Transcriptome profiling reveals major structural genes, transcription factors and biosynthetic pathways in refractory epilepsy in tropical region of China.

Published in:

BMC Neurology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12883-025-04216-2

By:

Ben, Xinyu;
Zhang, Peng;
Li, Chang;
Zou, Qin;
Cai, Yi;
Wang, Sheng;
Li, Chuanfa;
Feng, Renjun;
Li, Qifu

Publication type:

Article

Molecular Mechanisms of Plant Stress Memory: Roles of Non-Coding RNAs and Alternative Splicing.

Published in:

Plants (2223-7747), 2025, v. 14, n. 13, p. 2021, doi. 10.3390/plants14132021

By:

Sintaha, Mariz

Publication type:

Article

A novel splicing graph allows a direct comparison between exon-based and splice junction–based approaches to alternative splicing detection Open Access.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 3, p. 1, doi. 10.1093/bib/bbaf204

By:

Aquino, Jelard;
Witoslawski, Daniel;
Park, Steve;
Holder, Jessica;
Amei, Amei;
Han, Mira V

Publication type:

Article

Full-Length Transcriptome Sequencing Reveals Treg-Specific Isoform Expression upon Activation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6302, doi. 10.3390/ijms26136302

By:

Sato, Yohei;
Osada, Erika;
Manome, Yoshinobu

Publication type:

Article

Modulation of Neurexins Alternative Splicing by Cannabinoid Receptors 1 (CB1) Signaling.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 972, doi. 10.3390/cells14130972

By:

Innocenzi, Elisa;
Sciamanna, Giuseppe;
Zucchi, Alice;
Medici, Vanessa;
Cesari, Eleonora;
Farini, Donatella;
Elliott, David J.;
Sette, Claudio;
Grimaldi, Paola

Publication type:

Article

C.5 The generation of alternative transcripts as a method of regulating phosphorylation in Sonic Hedgehog (Shh) Subtype Medulloblastoma (MB).

Published in:

2025

By:

Ogawa, K;
Chahin, A;
Purzner, J;
Purzner, T

Publication type:

Abstract

A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02280-2

By:

Dai, Mingrui;
Shi, Yuhua;
Zhao, Hailin;
Hu, Yue;
Cong, Xianling;
Yu, Bin;
Zhang, Haihong;
Yu, Xianghui;
Wu, Hui

Publication type:

Article

Genetic analysis of a novel TSC1 splice mutation causing tuberous sclerosis without neurological phenotypes.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07906-6

By:

Yao, Xiu-juan;
Lin, Ying;
Zou, Jing;
Cai, Zun-lin;
Xu, Zi-Yan;
Li, Xiao-qin;
Chen, Qian;
Yu, Hong-ping;
Zhang, Jian-hui;
Ruan, Dan-dan;
Gao, Mei-zhu;
Zhang, Li;
Luo, Jie-wei;
Xie, Bao-song

Publication type:

Article

RNA-sequencing studies suggest that microRNAs and alternative splicing of pre-mRNAs modulate immune and inflammatory responses in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1597736

By:

Badia-Bringué, Gerard;
Alonso-Hearn, Marta

Publication type:

Article

Alternative splicing factor RAB3IP as a novel risk signature to predict the prognosis of colorectal cancer.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2959, doi. 10.7150/jca.110271

By:

Zhengwei Zhou;
Fei Gao;
Han Lei;
Haixuan Wen;
Jiaxi Tang;
Yulong Peng;
Lili Fan;
Lu Xu;
Guang Shu

Publication type:

Article

Molecular Consequences of a Missense PHF21A Variant, c.1285G > A, Associated With Syndromic Neurodevelopmental Disorder.

Published in:

Cellular & Molecular Neurobiology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10571-025-01584-8

By:

Gavilan, Cecilia M.;
Murata-Nakamura, Yumie;
Porter, Robert;
Cutler, Bradley;
Rai, Sehj;
Kim, Hyung-Goo;
Iwase, Shigeki

Publication type:

Article

RNA结合蛋白在植物抗病中的研究进展.

Published in:

Biotechnology Bulletin, 2025, v. 41, n. 6, p. 12, doi. 10.13560/j.cnki.biotech.bull.1985.2025-0056

By:

吕悦;
张杰伟;
王勃

Publication type:

Article

Involvement of dysregulated RNA binding protein and alternative splicing regulatory networks in diabetic nephropathy from type 2 albuminuric cohorts.

Published in:

BMC Nephrology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12882-025-04237-6

By:

Wang, Yu;
Zhang, Jingjing;
Tang, Qian

Publication type:

Article

Genomic and epigenomic insight into giga-chromosome architecture and adaptive evolution of royal lily (Lilium regale).

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61289-w

By:

Sun, Jie;
Wang, Xiangfeng;
Wang, Ke;
Meng, Dian;
Mu, Yu;
Zhang, Lili;
Wang, Jingxuan;
Yao, Gang;
Guo, Li

Publication type:

Article

Alternative splicing of squid is associated with sex-ratio allocation in the wasp Copidosomopsis nacoleiae.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11800-w

By:

Ouyang, Huili;
Li, Xuesheng;
Chen, Dongyu;
Zheng, Xia-Lin;
Lu, Wen;
Wang, Xiaoyun

Publication type:

Article

The Role of Alternative Splicing in Marine–Freshwater Divergence in Threespine Stickleback Open Access.

Published in:

Genome Biology & Evolution, 2025, v. 17, n. 6, p. 1, doi. 10.1093/gbe/evaf105

By:

Rodríguez-Ramírez, Carlos E;
Peichel, Catherine L

Publication type:

Article

Alternative Splicing of Functional Genes in Plant Growth, Development, and Stress Responses.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5864, doi. 10.3390/ijms26125864

By:

Liu, Guan;
Wang, Hanhui;
Gao, Huan;
Yu, Song;
Liu, Changhua;
Wang, Yang;
Sun, Yan;
Zhang, Dongye

Publication type:

Article

Full-Length Transcriptome of Testis and Ovary Provides Insights into Alternative Splicing During Gonadal Development in Litopenaeus vannamei.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5863, doi. 10.3390/ijms26125863

By:

Wang, Youyan;
Yu, Yang;
Wang, Yue;
Li, Fuhua

Publication type:

Article

HPTAS: An Alignment-Free Haplotype Phasing Algorithm Focused on Allele-Specific Studies Using Transcriptome Data.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5700, doi. 10.3390/ijms26125700

By:

Wang, Jianan;
Sun, Zhenyuan;
Wang, Guohua;
Miao, Yan

Publication type:

Article

Skin melanoma cells produce diverse gelsolin (GSN) isoforms, which play non-redundant roles in cells' proliferation and motility.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03876-x

By:

Mazurkiewicz-Stanek, Ewa;
Makowiecka, Aleksandra;
Kopernyk, Iryna;
Majkowski, Michał;
Boguszewska-Czubara, Anna;
Trombik, Tomasz;
Karpiński, Paweł;
Donizy, Piotr;
Mazur, Antonina J.

Publication type:

Article

Molecular Characterization of CnHd3a and Spatial Expression of Its Alternative Splicing Forms Associated with Flowering Transition and Flower Development in Coconut Palm (Cocos nucifera L.).

Published in:

Genes, 2025, v. 16, n. 6, p. 718, doi. 10.3390/genes16060718

By:

Maneeprasert, Pariya;
Thaisakun, Siriwan;
Thanananta, Theerachai;
Thanananta, Narumol;
Lokkamlue, Noppamart;
Mongkolsiriwatana, Chareerat

Publication type:

Article

Differential Recruitment of Pre-mRNA Splicing Factors to Alternatively Spliced Transcripts In Vivo.

Published in:

PLoS Biology, 2005, v. 3, n. 10, p. 1, doi. 10.1371/journal.pbio.0030374

By:

Mabon, Stephen A;
Misteli, Tom

Publication type:

Article

A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 1, doi. 10.1371/journal.pbio.0030158

By:

Han, Kyoungha;
Yeo, Gene;
An, Ping;
Burge, Christopher B;
Grabowski, Paula J

Publication type:

Article

Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome.

Published in:

PLoS Biology, 2004, v. 2, n. 11, p. 1, doi. 10.1371/journal.pbio.0020391

By:

Athanasiadis, Alekos;
Rich, Alexander;
Maas, Stefan

Publication type:

Article

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones.

Published in:

PLoS Biology, 2004, v. 2, n. 4, p. 1, doi. 10.1371/journal.pbio.0020162

By:

Imanishi, Tadashi;
Itoh, Takeshi;
Suzuki, Yutaka;
O'Donovan, Claire;
Fukuchi, Satoshi;
Koyanagi, Kanako O;
Barrero, Roberto A;
Tamura, Takuro;
Yamaguchi-Kabata, Yumi;
Tanino, Motohiko;
Yura, Kei;
Miyazaki, Satoru;
Ikeo, Kazuho;
Homma, Keiichi;
Kasprzyk, Arek;
Nishikawa, Tetsuo;
Hirakawa, Mika;
Thierry-Mieg, Jean;
Thierry-Mieg, Danielle;
Ashurst, Jennifer

Publication type:

Article

Adenine base-editing-mediated exon skipping induces gene knockout in cultured pig cells.

Published in:

Biotechnology Letters, 2022, v. 44, n. 1, p. 59, doi. 10.1007/s10529-021-03214-x

By:

Zhu, Xiang-xing;
Pan, Jia-sheng;
Lin, Tao;
Yang, Ye-cheng;
Huang, Qiu-yan;
Yang, Shuai-peng;
Qu, Zi-xiao;
Lin, Zi-sheng;
Wen, Jian-cong;
Yan, Ai-fen;
Feng, Juan;
Liu, Lian;
Zhang, Xiao-li;
Lu, Jia-hong;
Tang, Dong-sheng

Publication type:

Article

The aberrant expression of CD45 isoforms and levels of sex hormones in systemic lupus erythematosus.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 4, p. 1087, doi. 10.1007/s10067-021-05934-x

By:

Dong, Zhaoxia;
Zhang, Bin;
Rong, Ju;
Yang, Xinran;
Wang, Yongni;
Zhang, Qiaoxin;
Su, Zhongjing

Publication type:

Article

Regulation of a truncated isoform of AMP-activated protein kinase α (AMPKα) in response to hypoxia in the muscle of Pacific oyster Crassostrea gigas.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2013, v. 183, n. 5, p. 597, doi. 10.1007/s00360-013-0743-6

By:

Guévélou, Eric;
Huvet, Arnaud;
Sussarellu, Rossana;
Milan, Massimo;
Guo, Ximing;
Li, Li;
Zhang, Guofan;
Quillien, Virgile;
Daniel, Jean-Yves;
Quéré, Claudie;
Boudry, Pierre;
Corporeau, Charlotte

Publication type:

Article

Intron specificity in pre-mRNA splicing.

Published in:

Current Genetics, 2018, v. 64, n. 4, p. 777, doi. 10.1007/s00294-017-0802-8

By:

Mishra, Shravan Kumar;
Thakran, Poonam

Publication type:

Article

Special Issue: Epithelial-Mesenchymal Transition 2020.

Published in:

2022

By:

Thompson, Erik W.;
Sheng, Guojun

Publication type:

Editorial

Regulation of Alternative Splicing during Epithelial-Mesenchymal Transition.

Published in:

Cells Tissues Organs, 2022, v. 211, n. 2, p. 238, doi. 10.1159/000518249

By:

Lyu, Jingyi;
Cheng, Chonghui

Publication type:

Article

Successful detection, expression and purification of the alternatively spliced truncated Sm14 antigen of an Egyptian strain of Schistosoma mansoni.

Published in:

Journal of Helminthology, 2015, v. 89, n. 6, p. 764, doi. 10.1017/S0022149X14000571

By:

Ewaisha, R.E.;
Bahey-El-Din, M.;
Mossallam, S.F.;
Khalil, A.M.;
Aboushleib, H.M.

Publication type:

Article

dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation.

Published in:

Glycobiology, 2022, v. 32, n. 6, p. 518, doi. 10.1093/glycob/cwac004

By:

Missaghian, Parisa;
Dierker, Tabea;
Khosrowabadi, Elham;
Axling, Fredrik;
Eriksson, Inger;
Ghanem, Abdurrahman;
Kusche-Gullberg, Marion;
Kellokumpu, Sakari;
Kjellén, Lena

Publication type:

Article

The regulatory subunit MoB56 of PP2A phosphatase regulates pathogenicity, growth and development in a protein complex with the atypical catalytic subunit Ppg1 in the rice blast fungus Magnaporthe oryzae.

Published in:

Phytopathology Research, 2023, v. 5, n. 1, p. 1, doi. 10.1186/s42483-023-00165-1

By:

Wang, Rui-Jin;
Cui, Danrui;
Zhao, Rui;
Jin, Yujie;
Zeng, Wenhui;
Yang, Ye;
Qi, Linlu;
Xiang, Lihui;
Peng, You-Liang

Publication type:

Article

Association of high expression of CD44 in clinicopathological factors of endometrial cancer.

Published in:

Minerva Obstetrics & Gynecology, 2024, v. 76, n. 5, p. 410, doi. 10.23736/S2724-606X.23.05279-X

By:

RIANA, Gina M.;
PELUPESSY, Nugraha U.;
QADAR, Sriwijaya;
MISKAD, Upik;
ZAINUDDIN, Andi A.;
MADYA, Fatmawati;
LUKAS, Efendi

Publication type:

Article

Multi-omics identify ribosome related causal genes methylation, splicing, and expression in prostate cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02584-2

By:

Wei, Chengcheng;
He, Jingke;
Li, Yunfan;
Luo, Yu;
Song, Liangdong;
Han, Kun;
Zhang, Jindong;
Su, Shuai;
Wang, Delin

Publication type:

Article

IGF2BP3 prefers to regulate alternative splicing of genes associated with the progression of gastric cancer in AGS cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01880-1

By:

Zeng, Xiangyue;
Zhang, Yu;
Shapaer, Tiannake;
Abudoukelimu, Abulajiang;
Zhao, Zeliang;
Ma, Binlin

Publication type:

Article

Duchenne Muscular Dystrophy (DMD): overview and pathomechanism.

Published in:

European Journal of Translational & Clinical Medicine, 2023, v. 6, p. 19

By:

Ferlini, Alessandra

Publication type:

Article

MRG15 alternative splicing regulates CDK1 transcriptional activity in mouse cell senescence and myocardial regeneration.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08309-z

By:

Zhang, Yuan;
Wang, Huayu;
Li, Fang;
Dai, Hui;
Zhang, Ye

Publication type:

Article

LSM12 promotes the lung squamous cell carcinoma progression through mediating alternative splicing of ARRB1.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08193-7

By:

Wu, Lin;
Zhang, Fangyuan;
Chen, Huanhuan;
Zhao, Gang

Publication type:

Article

Glucocorticoids regulate the expression of Srsf1 through Hdac4/Foxc1 axis to induce apoptosis of osteoblasts.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07989-x

By:

Luo, Hong;
Wang, Tao;
Xie, Zhihong;
Li, Fanchao;
Yang, Chengyou;
Dong, Wentao;
Wu, Jianhua;
Wang, Qiang;
Xu, Fengyang;
Liu, Jiong;
Zhang, Fei;
Peng, Wuxun

Publication type:

Article

RBPMS inhibits bladder cancer metastasis by downregulating MYC pathway through alternative splicing of ANKRD10.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07842-1

By:

Yu, Jingtian;
Chen, Liang;
Wang, Gang;
Qian, Kaiyu;
Weng, Hong;
Yang, Zhonghua;
Zheng, Hang;
Lu, Mengxin

Publication type:

Article