Works matching DE "ADUCANUMAB"

Results: 142

Unveiling Aducanumab's safety profile: A comprehensive pharmacovigilance analysis.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0328076

By:

Ji, Huanhuan;
Zhao, Zongren;
Zhao, Chuanwei

Publication type:

Article

Monoclonal antibody therapy in Alzheimer's disease: an overview and vision.

Published in:

Brain Network & Modulation (BNM), 2024, v. 3, n. 2, p. 43, doi. 10.4103/BNM.BNM_14_23

By:

Bentley, Jonathan H.;
Bishop, Lindsey E.;
Broussard, John I.

Publication type:

Article

Donanemab: Not two without a third.

Published in:

Advances in Clinical & Experimental Medicine, 2023, v. 32, n. 10, p. 1085, doi. 10.17219/acem/172673

By:

Kurkinen, Markku

Publication type:

Article

Immunothérapie passive dans la maladie d'Alzheimer : état des lieux et applicabilité en population gériatrique.

Published in:

Gériatrie et Psychologie Neuropsychiatrie du Vieillissement, 2023, v. 21, n. 2, p. 233, doi. 10.1684/pnv.2023.1099

By:

Delrieu, Julien;
Ousset, Pierre Jean

Publication type:

Article

Actualités thérapeutiques dans la maladie d'Alzheimer : bientôt un traitement de fond ?

Published in:

Gériatrie et Psychologie Neuropsychiatrie du Vieillissement, 2022, v. 20, n. 2, p. 256, doi. 10.1684/pnv.2022.1042

By:

Villain, Nicolas

Publication type:

Article

Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1593989

By:

Kong, Lingti;
Yang, Xiaohu;
Xu, Jian

Publication type:

Article

A real-world safety surveillance study of aducanumab through the FDA adverse event reporting system.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1522058

By:

Huang, Jingjing;
Long, Xiaohong;
Chen, Chunyong

Publication type:

Article

Review of Advanced Drug Trials Focusing on the Reduction of Brain Beta-Amyloid to Prevent and Treat Dementia.

Published in:

Journal of Experimental Pharmacology, 2022, v. 14, p. 331, doi. 10.2147/JEP.S265626

By:

Decourt, Boris;
Noorda, Keith;
Noorda, Kevin;
Shi, Jiong;
Sabbagh, Marwan N

Publication type:

Article

Turning the tide on Alzheimer's disease: modulation of γ-secretase.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-021-00738-7

By:

Luo, Joanna E.;
Li, Yue-Ming

Publication type:

Article

Amyloid-Related Imaging Abnormalities With Anti-amyloid Antibodies for the Treatment of Dementia Due to Alzheimer's Disease.

Published in:

2022

By:

Withington, Charles G.;
Turner, R. Scott

Publication type:

Case Study

Oligomannate and Aducanumab: Novel Drugs for Alzheimer Disease.

Published in:

Ibnosina Journal of Medicine & Biomedical Sciences, 2020, v. 12, n. 4, p. 327, doi. 10.4103/ijmbs.ijmbs_114_20

By:

Rissardo, Jamir Pitton;
Caprara, Ana Letícia Fornari

Publication type:

Article

Oligomannate and Aducanumab: Novel Drugs for Alzheimer Disease.

Published in:

Ibnosina Journal of Medicine & Biomedical Sciences, 2020, v. 12, n. 4, p. 327, doi. 10.4103/ijmbs.ijmbs_114_20

By:

Rissardo, Jamir Pitton;
Fornari Caprara, Ana Letícia

Publication type:

Article

U.S. Food and Drug Administration Reasoning in Approval Decisions When Efficacy Evidence Is Borderline, 2013-2018.

Published in:

2021

By:

Janiaud, Perrine;
Irony, Telba;
Russek-Cohen, Estelle;
Goodman, Steven N.

Publication type:

journal article

The Problem of Aducanumab for the Treatment of Alzheimer Disease.

Published in:

2021

By:

Alexander, G. Caleb;
Karlawish, Jason

Publication type:

Editorial

Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 50, p. 12549, doi. 10.1523/JNEUROSCI.2080-16.2016

By:

Kastanenka, Ksenia V.;
Bussiere, Thierry;
Shakerdge, Naomi;
Fang Qian;
Weinreb, Paul H.;
Rhodes, Ken;
Bacskai, Brian J.

Publication type:

Article

Physician Perspectives on the Food and Drug Administration's Decision to Grant Accelerated Approval to Aducanumab for Alzheimer's Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 3, p. 614, doi. 10.1002/cpt.2954

By:

Dhruva, Sanket S.;
Kesselheim, Aaron S.;
Woloshin, Steven;
Ji, Robin Z.;
Lu, Zhigang;
Darrow, Jonathan J.;
Redberg, Rita F.

Publication type:

Article

Aducanumab and Accelerated Approval: Where Do We Go From Here?

Published in:: Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 726, doi. 10.1002/cpt.2546
Publication type:: Article

Toward Bridging Unmet Medical Need in Early Alzheimer's Disease: An Evaluation of Beta‐Amyloid (Aβ) Plaque Burden as a Potential Drug Development Tool.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 728, doi. 10.1002/cpt.2536

By:

Zhu, Hao;
Mehta, Mehul;
Huang, Shiew‐Mei;
Wang, Yaning

Publication type:

Article

Disease Modeling and Model‐Based Meta‐Analyses to Define a New Direction for a Phase III Program of Gantenerumab in Alzheimer's Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 857, doi. 10.1002/cpt.2535

By:

Retout, Sylvie;
Gieschke, Ronald;
Serafin, Daniel;
Weber, Cornelia;
Frey, Nicolas;
Hofmann, Carsten

Publication type:

Article

New and emerging drug therapies for Alzheimer disease.

Published in:

Australian Prescriber, 2024, v. 47, n. 3, p. 75, doi. 10.18773/austprescr.2024.021

By:

Waite, Louise M.

Publication type:

Article

Kleinová L, Cerman J, Hlávka J et al. Nové farmakologické možnosti v léčbě Alzheimerovy nemoci.

Published in:

Česká a Slovenská Neurologie a Neurochirurgie, 2023, v. 86, n. 4, p. 289

By:

Míšková, Iva

Publication type:

Article

Alzheimer's disease: the controversial approval of Aducanumab.

Published in:

2021

By:

Tagliavini, Fabrizio;
Tiraboschi, Pietro;
Federico, Antonio

Publication type:

Editorial

Safety Concerns in Neurological Clinical Trials: A Challenge That the FDA Must Resolve.

Published in:

Biomedicines, 2024, v. 12, n. 12, p. 2918, doi. 10.3390/biomedicines12122918

By:

Niazi, Sarfaraz K.

Publication type:

Article

The Fuzzy Border between the Functional and Dysfunctional Effects of Beta-Amyloid: A Synaptocentric View of Neuron–Glia Entanglement.

Published in:

Biomedicines, 2023, v. 11, n. 2, p. 484, doi. 10.3390/biomedicines11020484

By:

Fagiani, Francesca;
Fulop, Tamas;
Govoni, Stefano;
Lanni, Cristina

Publication type:

Article

The Major Hypotheses of Alzheimer's Disease: Related Nanotechnology-Based Approaches for Its Diagnosis and Treatment.

Published in:

Cells (2073-4409), 2023, v. 12, n. 23, p. 2669, doi. 10.3390/cells12232669

By:

Cáceres, César;
Heusser, Bernardita;
Garnham, Alexandra;
Moczko, Ewa

Publication type:

Article

Aducanumab, an investigational drug for AZ, submitted to FDA for priority review.

Published in:: Rhode Island Medical Journal, 2020, v. 103, n. 6, p. 96
Publication type:: Article

Biogen seeking FDA review in early 2020 for Aducanumab to treat early AD.

Published in:: Rhode Island Medical Journal, 2019, v. 102, n. 9, p. 56
Publication type:: Article

Therapeutic Approach to Alzheimer's Disease: Current Treatments and New Perspectives.

Published in:

Pharmaceutics, 2022, v. 14, n. 6, p. 1117, doi. 10.3390/pharmaceutics14061117

By:

Pardo-Moreno, Teresa;
González-Acedo, Anabel;
Rivas-Domínguez, Antonio;
García-Morales, Victoria;
García-Cozar, Francisco Jose;
Ramos-Rodríguez, Juan Jose;
Melguizo-Rodríguez, Lucía

Publication type:

Article

PET Imaging in Preclinical Anti-Aβ Drug Development.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 7, p. 1481, doi. 10.1007/s11095-022-03277-z

By:

Syvänen, Stina;
Meier, Silvio R.;
Roshanbin, Sahar;
Xiong, Mengfei;
Faresjö, Rebecca;
Gustavsson, Tobias;
Bonvicini, Gillian;
Schlein, Eva;
Aguilar, Ximena;
Julku, Ulrika;
Eriksson, Jonas;
Sehlin, Dag

Publication type:

Article

New drugs for Alzheimer’s disease: Aducanumab or Donanemab?

Published in:

Physiology & Pharmacology, 2024, v. 28, n. 3, p. 219, doi. 10.61186/phypha.28.3.219

By:

Joodaki, Mehran;
Shirazi, Mona Merati;
Hosseini, Nasrin

Publication type:

Article

Unraveling Alzheimer's: the promise of aducanumab, lecanemab, and donanemab.

Published in:

Egyptian Journal of Neurology, Psychiatry & Neurosurgery, 2024, v. 60, n. 1, p. 1, doi. 10.1186/s41983-024-00845-5

By:

Ameen, Taha Basit;
Kashif, Syeda Naveera;
Abbas, Syed Muhammad Iraj;
Babar, Kulsoom;
Ali, Syed Muhammad Sinaan;
Raheem, Abdul

Publication type:

Article

Advancing Alzheimer's care: a novel therapy with lecanemab.

Published in:

Egyptian Journal of Neurology, Psychiatry & Neurosurgery, 2023, v. 59, n. 1, p. 1, doi. 10.1186/s41983-023-00747-y

By:

Teli, Advait;
Dhande, Priti

Publication type:

Article

Aducanumab: an uprising hope with vague horizons.

Published in:

Egyptian Journal of Neurology, Psychiatry & Neurosurgery, 2023, v. 59, n. 1, p. 1, doi. 10.1186/s41983-023-00684-w

By:

Hazegh Fetratjoo, Delara;
Kargar, Alireza;
Noroozian, Maryam

Publication type:

Article

ABTrans: A Transformer-based Model for Predicting Interaction between Anti-Aβ Antibodies and Peptides.

Published in:

Interdisciplinary Sciences: Computational Life Sciences, 2025, v. 17, n. 1, p. 140, doi. 10.1007/s12539-024-00664-5

By:

Su, Yuhong;
Zeng, Xincheng;
Zhang, Lingfeng;
Bian, Yanlin;
Wang, Yangjing;
Ma, Buyong

Publication type:

Article

Symposium 08: Neuropsychological Considerations for Alzheimer's Disease Clinical Trials.

Published in:

2023

By:

Kiselica, Andrew;
Duff, Kevin

Publication type:

Abstract

Acquired Risk Factors that Influence Risk for Dementia and Possibly Alzheimer Disease.

Published in:

South Dakota Medicine, 2024, v. 77, n. 2, p. 87

By:

Novak, Eric;
Tochtrop, Matthew;
Schlagel, David;
Fuller, William

Publication type:

Article

Mining and analysis of adverse events associated with aducanumab: a real-world study using FDA Adverse Event Reporting System database.

Published in:

Expert Opinion on Drug Safety, 2025, v. 24, n. 4, p. 469, doi. 10.1080/14740338.2024.2448205

By:

Wu, Shuangshuang;
Qi, Yiming;
Jiang, Cheng;
Zheng, Junxian

Publication type:

Article

Anti-Amyloid Therapies for Alzheimer's Disease and the Amyloid Cascade Hypothesis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14499, doi. 10.3390/ijms241914499

By:

Fedele, Ernesto

Publication type:

Article

Treatment of Alzheimer's Disease: Beyond Symptomatic Therapies.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13900, doi. 10.3390/ijms241813900

By:

Buccellato, Francesca R.;
D'Anca, Marianna;
Tartaglia, Gianluca Martino;
Del Fabbro, Massimo;
Scarpini, Elio;
Galimberti, Daniela

Publication type:

Article

Aducanumab—Hope or Disappointment for Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4367, doi. 10.3390/ijms24054367

By:

Wojtunik-Kulesza, Karolina;
Rudkowska, Monika;
Orzeł-Sajdłowska, Anna

Publication type:

Article

Using Optogenetics to Model Cellular Effects of Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4300, doi. 10.3390/ijms24054300

By:

Tiwari, Prabhat;
Tolwinski, Nicholas S.

Publication type:

Article

Symptomatic and Disease-Modifying Therapy Pipeline for Alzheimer's Disease: Towards a Personalized Polypharmacology Patient-Centered Approach.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9305, doi. 10.3390/ijms23169305

By:

Morató, Xavier;
Pytel, Vanesa;
Jofresa, Sara;
Ruiz, Agustín;
Boada, Mercè

Publication type:

Article

New Possibilities in the Therapeutic Approach to Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 8902, doi. 10.3390/ijms23168902

By:

Doroszkiewicz, Julia;
Mroczko, Barbara

Publication type:

Article

Consecutive Aromatic Residues Are Required for Improved Efficacy of β-Sheet Breakers.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 5247, doi. 10.3390/ijms23095247

By:

Jarmuła, Adam;
Zubalska, Monika;
Stępkowski, Dariusz

Publication type:

Article

Aducanumab and Its Effects on Tau Pathology: Is This the Turning Point of Amyloid Hypothesis?

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2011, doi. 10.3390/ijms23042011

By:

Silvestro, Serena;
Valeri, Andrea;
Mazzon, Emanuela

Publication type:

Article

Optimal anti-amyloid-beta therapy for Alzheimer's disease via a personalized mathematical model.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pcbi.1010481

By:

Hao, Wenrui;
Lenhart, Suzanne;
Petrella, Jeffrey R.

Publication type:

Article

Disease-modifying treatments in Alzheimer's disease.

Published in:

Journal of Neurology, 2023, v. 270, n. 4, p. 2342, doi. 10.1007/s00415-023-11602-8

By:

Edwards, Marc;
Corkill, Robin

Publication type:

Article

Correction to: Characterization of exposure–Clinical Dementia Rating–Sum of Boxes relationship in subjects with early Alzheimer's disease from the aducanumab Phase 3 trials.

Published in:

2023

By:

Muralidharan, Kumar Kandadi;
Kowalski, Kenneth G.;
Tong, Xiao;
Haeberlein, Samantha Budd;
Rajagovindan, Rajasimhan;
Nestoro, Ivan

Publication type:

Correction Notice

Characterization of exposure–Clinical Dementia Rating–Sum of Boxes relationship in subjects with early Alzheimer's disease from the aducanumab Phase 3 trials.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 1, p. 45, doi. 10.1007/s10928-022-09839-3

By:

Muralidharan, Kumar Kandadi;
Kowalski, Kenneth G.;
Tong, Xiao;
Haeberlein, Samantha Budd;
Rajagovindan, Rajasimhan;
Nestorov, Ivan

Publication type:

Article

Application of <sup>89</sup>Zr-DFO*-immuno-PET to assess improved target engagement of a bispecific anti-amyloid-ß monoclonal antibody.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2023, v. 50, n. 5, p. 1306, doi. 10.1007/s00259-023-06109-3

By:

Stergiou, N.;
Wuensche, T. E.;
Schreurs, M.;
Mes, I.;
Verlaan, M.;
Kooijman, E. J. M.;
Windhorst, A. D.;
Helboe, L.;
Vergo, S.;
Christensen, S.;
Asuni, A. A.;
Jensen, A.;
Van Dongen, G. A. M. S.;
Bang-Andersen, B.;
Vugts, D. J.;
Beaino, W.

Publication type:

Article