Works matching DE "ACID ceramidase"

Results: 26

Spinal muscular atrophy associated with progressive myoclonus epilepsy.

Published in:

Epileptic Disorders, 2016, v. 18, p. S128, doi. 10.1684/epd.2016.0858

By:

Topaloglu, Haluk;
Melki, Judith

Publication type:

Article

Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase.

Published in:

Angewandte Chemie, 2015, v. 127, n. 2, p. 495, doi. 10.1002/ange.201409042

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Acid ceramidase deficiency: Farber disease and SMA-PME.

Published in:

2018

By:

Yu, Fabian P. S.;
Amintas, Samuel;
Levade, Thierry;
Medin, Jeffrey A.

Publication type:

journal article

Acid Ceramidase Promotes Nuclear Export of PTEN through Sphingosine 1-Phosphate Mediated Akt Signaling.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076593

By:

Beckham, Thomas H.;
Cheng, Joseph C.;
Lu, Ping;
Marrison, S. Tucker;
Norris, James S.;
Liu, Xiang

Publication type:

Article

Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062715

By:

Simonaro, Calogera M.;
Sachot, Sylvain;
Ge, Yi;
He, Xingxuan;
DeAngelis, Victor A.;
Eliyahu, Efrat;
Leong, Daniel J.;
Sun, Hui B.;
Mason, Jeffrey B.;
Haskins, Mark E.;
Richardson, Dean W.;
Schuchman, Edward H.

Publication type:

Article

Blockade of Lysosomal Acid Ceramidase Induces GluN2B-Dependent Tau Phosphorylation in Rat Hippocampal Slices.

Published in:

Neural Plasticity, 2014, v. 2014, p. 1, doi. 10.1155/2014/196812

By:

Laurier-Laurin, Marie-Elaine;
DeMontigny, Audrée;
Essis, Suzanne Attiori;
Cyr, Michel;
Massicotte, Guy

Publication type:

Article

Identification of a Novel ASAH1 Gene Mutation in Spinal Muscular Atrophy with Progressive Myoclonic Epilepsy.

Published in:

Iranian Journal of Child Neurology, 2024, v. 18, n. 3, p. 131, doi. 10.22037/ijcn.v18i3.44081

By:

Ahangari, Najmeh;
Arab, Fatemeh;
Babaei, Meisam

Publication type:

Article

Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 3, p. 635, doi. 10.1007/s00280-012-2050-4

By:

Morad, Samy;
Messner, Maria;
Levin, Jonathan;
Abdelmageed, Noha;
Park, Hyejung;
Merrill, Alfred;
Cabot, Myles

Publication type:

Article

Construction of Conditional Acid Ceramidase Knockout Mice and in vivo Effects on Oocyte Development and Fertility.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2012, v. 30, n. 3, p. 735, doi. 10.1159/000341453

By:

Eliyahu, Efrat;
Shtraizent, Nataly;
Shalgi, Ruth;
Schuchman, Edward H.

Publication type:

Article

Signalling Effects Induced by Acid Ceramidase in Human Epithelial Or Leukemic Cell Lines.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 5, p. 1092, doi. 10.33594/000000074

By:

Baduva, Käthe;
Büchter, Lara;
Kreyenkamp, Katja;
Westphal, Linnea;
Wilker, Barbara;
Kohnen, Marcus;
Schuchman, Edward H.;
Edwards, Michael J.;
Becker, Katrin Anne;
Gulbins, Erich;
Carpinteiro, Alexander

Publication type:

Article

Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177805

By:

Bai, Aiping;
Mao, Cungui;
Jenkins, Russell W.;
Szulc, Zdzislaw M.;
Bielawska, Alicja;
Hannun, Yusuf A.

Publication type:

Article

Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90219-1

By:

Lai, Michele;
Amato, Rachele;
La Rocca, Veronica;
Bilgin, Mesut;
Freer, Giulia;
Spezia, Piergiorgio;
Quaranta, Paola;
Piomelli, Daniele;
Pistello, Mauro

Publication type:

Article

Genetic Variation in Acid Ceramidase Predicts Non-completion of an Exercise Intervention.

Published in:

Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00781

By:

Lewis, Lauren S.;
Huffman, Kim M.;
Smith, Ira J.;
Donahue, Mark P.;
Slentz, Cris A.;
Houmard, Joseph A.;
Hubal, Monica J.;
Hoffman, Eric P.;
Hauser, Elizabeth R.;
Siegler, Ilene C.;
Kraus, William E.

Publication type:

Article

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.

Published in:

Cancers, 2023, v. 15, n. 24, p. 5866, doi. 10.3390/cancers15245866

By:

Ung, Johnson;
Tan, Su-Fern;
Fox, Todd E.;
Shaw, Jeremy J. P.;
Taori, Maansi;
Horton, Bethany J.;
Golla, Upendarrao;
Sharma, Arati;
Szulc, Zdzislaw M.;
Wang, Hong-Gang;
Chalfant, Charles E.;
Cabot, Myles C.;
Claxton, David F.;
Loughran Jr., Thomas P.;
Feith, David J.

Publication type:

Article

Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.

Published in:

Journal of Biochemistry, 2015, v. 158, n. 4, p. 309, doi. 10.1093/jb/mvv039

By:

Naoki Mizutani;
Minami Inoue;
Yukari Omori;
Hiromi Ito;
Keiko Tamiya-Koizumi;
Akira Takagi;
Tetsuhito Kojima;
Mitsuhiro Nakamura;
Soichiro Iwaki;
Masahiro Nakatochi;
Motoshi Suzuki;
Yoshinori Nozawa;
Takashi Murate

Publication type:

Article

Spinal Muscular Atrophy with Progressive Myoclonic Epilepsy (SMA-PME): three new cases and review of the mutational spectrum.

Published in:

Italian Journal of Pediatrics, 2023, v. 49, n. 1, p. 1, doi. 10.1186/s13052-023-01474-z

By:

Najafi, Ali;
Tasharrofi, Behnoosh;
Zandsalimi, Farshid;
Rasulinezhad, Maryam;
Ghahvechi Akbari, Masood;
Zamani, Gholamreza;
Ashrafi, Mahmoud Reza;
Heidari, Morteza

Publication type:

Article

Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis.

Published in:

2020

By:

Gardner, Aaron I.;
Haq, Iram J.;
Simpson, A. John;
Becker, Katrin A.;
Gallagher, John;
Saint-Criq, Vinciane;
Verdon, Bernard;
Mavin, Emily;
Trigg, Alexandra;
Gray, Michael A.;
Koulman, Albert;
McDonnell, Melissa J.;
Fisher, Andrew J.;
Kramer, Elizabeth L.;
Clancy, John P.;
Ward, Christopher;
Schuchman, Edward H.;
Gulbins, Erich;
Brodlie, Malcolm

Publication type:

journal article

Fragment-Based Hologram QSAR Studies on a Series of2,4-Dioxopyrimidine-1-Carboxamides As Highly Potent Inhibitors of Acid Ceramidase.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, p. 139

By:

Xiang-Lin Yang;
Yuan Zhou;
Xin-Ling Liu

Publication type:

Article

Molecular Markers of Therapy-Resistant Glioblastoma and Potential Strategy to Combat Resistance.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1765, doi. 10.3390/ijms19061765

By:

Nguyen, Ha S.;
Shabani, Saman;
Awad, Ahmed J.;
Kaushal, Mayank;
Doan, Ninh

Publication type:

Article

Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges.

Published in:

Pharmaceutics, 2018, v. 10, n. 2, p. 45, doi. 10.3390/pharmaceutics10020045

By:

Nguyen, Ha S.;
Awad, Ahmed J.;
Shabani, Saman;
Doan, Ninh

Publication type:

Article

Pharmacophore elucidation and 3D-QSAR analysis of a new class of highly potent inhibitors of acid ceramidase based on maximum common substructure and field fit alignment methods.

Published in:

Journal of the Iranian Chemical Society, 2014, v. 11, n. 5, p. 1329, doi. 10.1007/s13738-013-0402-6

By:

Pirhadi, Somayeh;
Shiri, Fereshteh;
Ghasemi, Jahan

Publication type:

Article

Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 2, p. 485, doi. 10.1002/anie.201409042

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Inside Cover: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. Int. Ed. 2/2015).

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 2, p. 366, doi. 10.1002/anie.201410931

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Pathological manifestations of Farber disease in a new mouse model.

Published in:

Biological Chemistry, 2018, v. 399, n. 10, p. 1183, doi. 10.1515/hsz-2018-0170

By:

Beckmann, Nadine;
Kadow, Stephanie;
Schumacher, Fabian;
Göthert, Joachim R.;
Kesper, Stefanie;
Draeger, Annette;
Schulz-Schaeffer, Walter J.;
Jiang Wang;
Becker, Jan U.;
Kramer, Melanie;
Kühn, Claudine;
Kleuser, Burkhard;
Becker, Katrin Anne;
Gulbins, Erich;
Carpinteiro, Alexander

Publication type:

Article

Highlight: sphingolipids in infectious biology and immunology.

Published in:

Biological Chemistry, 2018, v. 399, n. 10, p. 1113, doi. 10.1515/hsz-2018-0341

By:

Carpinteiro, Alexander;
Becker, Katrin Anne;
Gulbins, Erich

Publication type:

Article

The molecular medicine of acid ceramidase.

Published in:

Biological Chemistry, 2015, v. 396, n. 6/7, p. 759, doi. 10.1515/hsz-2014-0290

By:

Frohbergh, Michael;
Xingxuan He;
Schuchman, Edward H.

Publication type:

Article