Works matching DE "ABL1 gene"

Results: 78

c-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential.

Published in:

Journal of Parkinson's Disease, 2017, v. 7, n. 4, p. 589, doi. 10.3233/JPD-171191

By:

Brahmachari, Saurav;
Karuppagounder, Senthilkumar S.;
Ge, Preston;
Lee, Saebom;
Dawson, Valina L.;
Dawson, Ted M.;
Han Seok Ko

Publication type:

Article

Modelling c-Abl Signalling in Activated Neutrophils: the Anti-inflammatory Effect of Seliciclib.

Published in:

BioDiscovery, 2017, p. 1, doi. 10.7750/BioDiscovery.2013.7.4

By:

Jackson, Robert C.;
Radivoyevitch, Tomas

Publication type:

Article

Chronic myelogenous leukemia-like hematological malignancy with t(8;22) in a 26-year-old pregnant woman: A case report.

Published in:

2016

By:

YOU‑WEN QIN;
YI‑NING YANG;
PING BAI;
CHUN WANG

Publication type:

Case Study

A case of myeloproliferative neoplasm with a normal complete blood cell count: A novel problem of the JAK2 era.

Published in:

2016

By:

XIU-PENG YE;
SHEN BAO;
HUAN-MIN GAO;
YING GUO;
YU-PING WEI

Publication type:

Case Study

High expression of LMO2 predicts a favorable outcome in adult patients with BCR/ABL negative B-cell acute lymphoblastic leukemia.

Published in:

Oncology Letters, 2016, v. 11, n. 3, p. 1917, doi. 10.3892/ol.2016.4127

By:

ALY, RABAB M.;
TAALAB, MONA M.;
ABDSALAM, EMAN M.;
ELYAMANY, OMAR H.;
HASAN, OMAR E.

Publication type:

Article

c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer.

Published in:

Oncogene, 2014, v. 33, n. 36, p. 4508, doi. 10.1038/onc.2013.399

By:

Fiore, L S;
Ganguly, S S;
Sledziona, J;
Cibull, M L;
Wang, C;
Richards, D L;
Neltner, J M;
Beach, C;
McCorkle, J R;
Kaetzel, D M;
Plattner, R

Publication type:

Article

A novel BCR-ABL1 fusion gene with genetic heterogeneity indicates a good prognosis in a chronic myeloid leukemia case.

Published in:

Molecular Cytogenetics (17558166), 2017, v. 10, p. 1, doi. 10.1186/s13039-017-0322-8

By:

Fen Zhou;
Runming Jin;
Yu Hu;
Heng Mei

Publication type:

Article

c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemic sclerosis dermal fibroblasts.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 405, n. 1/2, p. 169, doi. 10.1007/s11010-015-2408-0

By:

Karimizadeh, Elham;
Motamed, Nasrin;
Jafarinejad-Farsangi, Saeideh;
Gharibdoost, Farhad;
Jamshidi, Ahmadreza;
Mahmoudi, Mahdi

Publication type:

Article

ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.

Published in:

Science Signaling, 2016, v. 9, n. 413, p. 1, doi. 10.1126/scisignal.aad3210

By:

Jun Wang;
Rouse, Clay;
Jasper, Jeff S.;
Pendergast, Ann Marie

Publication type:

Article

Defining the target and the effect of imatinib on the filarial c-Abl homologue.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005690

By:

O’Connell, Elise M.;
Kamenyeva, Olena;
Lustigman, Sara;
Bell, Aaron;
Nutman, Thomas B.

Publication type:

Article

Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/683097

By:

Cesareni, Gianni;
Di Bartolomeo, Claudia;
Diederich, Marc;
Gonfloni, Stefania;
Maiani, Emiliano

Publication type:

Article

Fluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase Function.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133590

By:

Grover, Prerna;
Shi, Haibin;
Baumgartner, Matthew;
Camacho, Carlos J.;
Smithgall, Thomas E.

Publication type:

Article

Flow Cytometric Immunobead Assay for Detection of BCR-ABL1 Fusion Proteins in Chronic Myleoid Leukemia: Comparison with FISH and PCR Techniques.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130360

By:

Recchia, Anna Grazia;
Caruso, Nadia;
Bossio, Sabrina;
Pellicanò, Mariavaleria;
De Stefano, Laura;
Franzese, Stefania;
Palummo, Angela;
Abbadessa, Vincenzo;
Lucia, Eugenio;
Gentile, Massimo;
Vigna, Ernesto;
Caracciolo, Clementina;
Agostino, Antolino;
Galimberti, Sara;
Levato, Luciano;
Stagno, Fabio;
Molica, Stefano;
Martino, Bruno;
Vigneri, Paolo;
Di Raimondo, Francesco

Publication type:

Article

Constitutive Activity in an Ancestral Form of Abl Tyrosine Kinase.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131062

By:

Aleem, Saadat U.;
Craddock, Barbara P.;
Miller, W. Todd

Publication type:

Article

Molecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and Coevolution.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130203

By:

Tse, Amanda;
Verkhivker, Gennady M.

Publication type:

Article

Inhibition of c-Abl Kinase Activity Renders Cancer Cells Highly Sensitive to Mitoxantrone.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105526

By:

Alpay, Kemal;
Farshchian, Mehdi;
Tuomela, Johanna;
Sandholm, Jouko;
Aittokallio, Kaappo;
Siljamäki, Elina;
Kallio, Marko;
Kähäri, Veli-Matti;
Hietanen, Sakari

Publication type:

Article

Abl Family Kinases Regulate Endothelial Barrier Function In Vitro and in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0085231

By:

Chislock, Elizabeth M.;
Pendergast, Ann Marie

Publication type:

Article

Regulatory Effects of Sestrin 3 (SESN3) in BCR-ABL Expressing Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078780

By:

Vakana, Eliza;
Arslan, Ahmet Dirim;
Szilard, Amy;
Altman, Jessica K.;
Platanias, Leonidas C.

Publication type:

Article

MicroRNA-4723 Inhibits Prostate Cancer Growth through Inactivation of the Abelson Family of Nonreceptor Protein Tyrosine Kinases.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078023

By:

Arora, Sumit;
Saini, Sharanjot;
Fukuhara, Shinichiro;
Majid, Shahana;
Shahryari, Varahram;
Yamamura, Soichiro;
Chiyomaru, Takeshi;
Deng, Guoren;
Tanaka, Yuichiro;
Dahiya, Rajvir

Publication type:

Article

Low Expression of miR-196b Enhances the Expression of BCR-ABL1 and HOXA9 Oncogenes in Chronic Myeloid Leukemogenesis.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068442

By:

Liu, Yue;
Zheng, Wenling;
Song, Yanbin;
Ma, Wenli;
Yin, Hong

Publication type:

Article

Neuroprotective Efficacy of a New Brain-Penetrating C-Abl Inhibitor in a Murine Parkinson’s Disease Model

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0065129

By:

Imam, Syed Z.;
Trickler, William;
Kimura, Shinya;
Binienda, Zbigniew K.;
Paule, Merle G.;
Slikker Jr, William;
Li, Senlin;
Clark, Robert A.;
Ali, Syed F.

Publication type:

Article

Sensitive Detection of Pre-Existing BCR-ABL Kinase Domain Mutations in CD34+ Cells of Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia Patients Is Associated with Imatinib Resistance: Implications in the Post-Imatinib Era.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055717

By:

Iqbal, Zafar;
Aleem, Aamer;
Iqbal, Mudassar;
Naqvi, Mubashar Iqbal;
Gill, Ammara;
Taj, Abid Sohail;
Qayyum, Abdul;
ur-Rehman, Najeeb;
Khalid, Ahmad Mukhtar;
Shah, Ijaz Hussain;
Khalid, Muhammad;
Haq, Riazul;
Khan, Mahwish;
Baig, Shahid Mahmood;
Jamil, Abid;
Abbas, Muhammad Naeem;
Absar, Muhammad;
Mahmood, Amer;
Rasool, Mahmood;
Akhtar, Tanveer

Publication type:

Article

Heterogeneous Nuclear Ribonucleoprotein K Interacts with Abi-1 at Postsynaptic Sites and Modulates Dendritic Spine Morphology.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027045

By:

Proepper, Christian;
Steinestel, Konrad;
Schmeisser, Michael J.;
Heinrich, Jutta;
Steinestel, Julie;
Bockmann, Juergen;
Liebau, Stefan;
Boeckers, Tobias M.

Publication type:

Article

A role for c-Abl in cell senescence and spontaneous immortalization.

Published in:

Age (0161-9152), 2013, v. 35, n. 4, p. 1251, doi. 10.1007/s11357-012-9452-4

By:

Zhang, Man;
Li, Lili;
Wang, Zhongfeng;
Liu, Huijuan;
Hou, Junlin;
Zhang, Min;
Hao, Aijun;
Liu, Yun;
He, Guang;
Shi, Yongyong;
He, Lin;
Wang, Xueying;
Wan, Yue;
Li, Baojie

Publication type:

Article

Evaluation of the Abelson gene as a control gene for real-time quantitative PCR in multiple myeloma.

Published in:

2014

By:

Zhang, Yao;
Ruan, Guo-Rui

Publication type:

Letter

Incidence and clinical importance of BCR-ABL1 mutations in Iranian patients with chronic myeloid leukemia on imatinib.

Published in:

Journal of Human Genetics, 2015, v. 60, n. 5, p. 253, doi. 10.1038/jhg.2015.11

By:

Rostami, Golale;
Hamid, Mohammad;
Yaran, Majid;
Khani, Mohsen;
Karimipoor, Morteza

Publication type:

Article

Neural mechanisms underlying stress resilience in Ahi1 knockout mice: relevance to neuropsychiatric disorders.

Published in:

Molecular Psychiatry, 2014, v. 19, n. 2, p. 243, doi. 10.1038/mp.2013.123

By:

Lotan, A;
Lifschytz, T;
Slonimsky, A;
Broner, E C;
Greenbaum, L;
Abedat, S;
Fellig, Y;
Cohen, H;
Lory, O;
Goelman, G;
Lerer, B

Publication type:

Article

Differential effects of dosing regimen on the safety and efficacy of dasatinib: retrospective exposure—response analysis of a Phase III study.

Published in:

Clinical Pharmacology, 2013, v. 5, p. 85, doi. 10.2147/CPAA.S42796

By:

Xiaoning Wang;
Roy, Amit;
Hochhaus, Andreas;
Kantarjian, Hagop M.;
Tai-Tsang Chen;
Shah, Neil P.

Publication type:

Article

Abl1 inhibitory contaminants leach from plastic tubes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 2, p. 340, doi. 10.3109/14756366.2015.1022171

By:

Chen, Hui;
Blanchaert, Bart;
Shinde, Abhijit Babaji;
Adams, Erwin;
Rozenski, Jef;
Baes, Myriam;
Van Schepdael, Ann

Publication type:

Article

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.

Published in:

Scientific Reports, 2015, p. 12974, doi. 10.1038/srep12974

By:

Huang, Yen-Hua;
Henriques, Sónia T.;
Wang, Conan K.;
Thorstholm, Louise;
Daly, Norelle L.;
Kaas, Quentin;
Craik, David J.

Publication type:

Article

A BCR-ABL1 cutoff of 1.5% at 3 months, determined by the GeneXpert system, predicts an optimal response in patients with chronic myeloid leukemia.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173532

By:

García-Gutiérrez, Valentín;
Gómez-Casares, María T.;
Puerta, José M.;
Alonso-Domínguez, Juan M.;
Osorio, Santiago;
Hernández-Boluda, Juan C.;
Collado, Rosa;
Ramírez, María J.;
Ibáñez, Fátima;
Martín, María L.;
Rodríguez-Gambarte, Juan D.;
Martínez-Laperche, Carolina;
Gómez, Montse;
Fiallo, Dolly V.;
Redondo, Sara;
Rodríguez, Alicia;
Ruiz-Nuño, Concepción;
Steegmann, Juan L.;
Jiménez-Velasco, Antonio;
null, null

Publication type:

Article

The Capable ABL: What Is Its Biological Function?

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 7, p. 1188, doi. 10.1128/MCB.01454-13

By:

Wang, Jean Y. J.

Publication type:

Article

Are submicroscopic chromosomal inversions predisposing factors for the t(9;22)(q34;q11.2) translocation in chronic myeloid leukemia?

Published in:

Molecular Cytogenetics (17558166), 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13039-015-0116-9

By:

González García, Juan Ramón;
Domínguez Cruz, Martín Daniel;
Gutiérrez, César Borjas

Publication type:

Article

Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation.

Published in:

Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8722-6-64

By:

Qi Shen;
Sichu Liu;
Yu Chen;
Lijian Yang;
Shaohua Chen;
Xiuli Wu;
Bo Li;
Yuhong Lu;
Kanger Zhu;
Yangqiu Li

Publication type:

Article

Primary myelofibrosis and its targeted therapy.

Published in:

2017

By:

Shantzer, Lindsey;
Berger, Kristin;
Pu, Jeffrey;
Pu, Jeffrey J

Publication type:

journal article

BCR-ABL-positive acute myeloid leukemia: About one case treated with ponatinib.

Published in:

2017

By:

Maël, Heiblig;
Arnaud, Pigneux;
Audrey, Bidet;
Evelyne, Callet-Bauchu;
Kaddour, Chabane;
Pierre-Yves, Dumas;
Gilles, Salles;
Maël, Heiblig

Publication type:

Case Study

Erratum to: BCR-ABL-positive acute myeloid leukemia: About one case treated with ponatinib.

Published in:

2017

By:

Pigneux, Arnaud;
Heiblig, Maël;
Callet-Bauchu, Evelyne;
Chabane, Kaddour;
Bidet, Audrey;
Dumas, Pierre-Yves;
Salles, Gilles;
Heiblig, Maël

Publication type:

corrected article

Comparative study of BCR-ABL1 quantification: Xpert assay, a feasible solution to standardization concerns.

Published in:

Annals of Hematology, 2012, v. 91, n. 8, p. 1245, doi. 10.1007/s00277-012-1468-4

By:

López-Jorge, C.;
Gómez-Casares, M.;
Jiménez-Velasco, A.;
García-Bello, M.;
Barrios, M.;
Lopez, J.;
Iglesia, S.;
Ramírez, T.;
Sánchez, G.;
Heiniger, A.;
Molero, T.

Publication type:

Article

Hypothesis: upfront use of ABL kinase inhibitor combination, either simultaneously or sequentially, in high-risk Ph leukemias?

Published in:

Annals of Hematology, 2010, v. 89, n. 6, p. 531, doi. 10.1007/s00277-010-0907-3

By:

Carella, A.

Publication type:

Article

Semi-random mutagenesis profile of BCR-ABL during imatinib resistance acquirement in K562 cells.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 6, p. 9409, doi. 10.3892/mmr.2017.7835

By:

YAN DONG;
XIAOTONG GAO;
YINGXIN ZHAO;
MENGYING WEI;
LINGMIN XU;
GUODONG YANG;
LI LIU

Publication type:

Article

Prevalence and outcomes of uncommon BCR‐ABL1 fusion transcripts in patients with chronic myeloid leukaemia: data from a single centre.

Published in:

British Journal of Haematology, 2018, v. 182, n. 5, p. 693, doi. 10.1111/bjh.15453

By:

Qin, Ya‐Zhen;
Jiang, Qian;
Jiang, Hao;
Lai, Yue‐Yun;
Shi, Hong‐Xia;
Chen, Wen‐Min;
Yu, Lu;
Huang, Xiao‐Jun

Publication type:

Article

Factors influencing long-term efficacy and tolerability of bosutinib in chronic phase chronic myeloid leukaemia resistant or intolerant to imatinib.

Published in:

British Journal of Haematology, 2016, v. 172, n. 1, p. 97, doi. 10.1111/bjh.13801

By:

Brümmendorf, Tim H.;
Cortes, Jorge E.;
Khoury, Hanna J.;
Kantarjian, Hagop M.;
Kim, Dong‐Wook;
Schafhausen, Philippe;
Conlan, Maureen G.;
Shapiro, Mark;
Turnbull, Kathleen;
Leip, Eric;
Gambacorti‐Passerini, Carlo;
Lipton, Jeff H.

Publication type:

Article

BCR-ABL1 in leukemia: Disguise master outplays riding shotgun.

Published in:

Journal of Cancer Research & Therapeutics, 2013, v. 9, n. 1, p. 6, doi. 10.4103/0973-1482.110339

By:

Rana, Aamir;
Ali, Ghulam M.;
Ali, Shaukat;
Khan, Ammara;
Mansoor, Sajid;
Malik, Shazia;
Farooqi, Ammad A.

Publication type:

Article

Breakpoint cluster region-c-abl oncogene 1, non-receptor tyrosine kinase signaling: Current patterns of the versatile regulator revisited.

Published in:

Journal of Cancer Research & Therapeutics, 2013, v. 9, n. 1, p. 3, doi. 10.4103/0973-1482.110338

By:

Rana, Aamir;
Ali, Ghulam M.;
Ali, Shaukat;
Khan, Ammara;
Sabiha, Bibi;
Malik, Shazia;
Riaz, Asma M.;
Farooqi, Ammad A.

Publication type:

Article

Hippo signaling: to die or not to die.

Published in:

Cell Death & Differentiation, 2013, v. 20, n. 10, p. 1287, doi. 10.1038/cdd.2013.100

By:

Aqeilan, R I

Publication type:

Article

Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells.

Published in:

Science Translational Medicine, 2016, v. 8, n. 355, p. 1, doi. 10.1126/scitranslmed.aag1180

By:

Carter, Bing Z.;
Po Yee Mak;
Hong Mu;
Hongsheng Zhou;
Mak, Duncan H.;
Schober, Wendy;
Leverson, Joel D.;
Bin Zhang;
Bhatia, Ravi;
Xuelin Huang;
Cortes, Jorge;
Kantarjian, Hagop;
Konopleva, Marina;
Andreeff, Michael

Publication type:

Article

BCR-ABL fusion protein detection in peripheral blood and bone marrow samples of adult precursor B-cell acute lymphoblastic leukemia patients using the flow cytometric immunobead assay.

Published in:

Clinical Chemistry & Laboratory Medicine, 2012, v. 50, n. 9, p. 1657, doi. 10.1515/cclm-2011-0686

By:

Grigoriou, Eirini E.;
Psarra, Katerina K.;
Garofalaki, Maria K.;
Tziotziou, Eirini C.;
Papasteriades, Chryssa A.

Publication type:

Article

t(1;9)(p34;q34)/SFPQ-ABL1 Fusion in a Patient with Ph-Like Common B-Cell Acute Lymphoblastic Leukemia.

Published in:

Acta Haematologica, 2017, v. 137, n. 1, p. 40, doi. 10.1159/000452265

By:

Sheng, Guangying;
Zeng, Zhao;
Pan, Jinlan;
Wang, Qinrong;
Yao, Hong;
Wen, Lijun;
Ma, Liang;
Wu, Depei;
Chen, Suning

Publication type:

Article

The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.

Published in:

Cell Communication & Signaling, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12964-015-0119-5

By:

Saki Sekino;
Yuriko Kashiwagi;
Hitoshi Kanazawa;
Kazuki Takada;
Takashi Baba;
Seiichi Sato;
Hiroki Inoue;
Masaki Kojima;
Katsuko Tani

Publication type:

Article

Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.

Published in:

Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-145

By:

Steinestel, Konrad;
Brüderlein, Silke;
Lennerz, Jochen K.;
Steinestel, Julie;
Kraft, Klaus;
Pröpper, Christian;
Meineke, Viktor;
Möller, Peter

Publication type:

Article