Works matching Cyclin-dependent kinases

Results: 5000

Identification of Potential Phytochemicals Against Cyclin-Dependent Kinase 1 and Cyclin-Dependent Kinase 2: A Molecular Docking and Molecular Dynamic Approach.

Published in:

Indian Journal of Pharmaceutical Sciences, 2024, v. 86, n. 1, p. 322, doi. 10.36468/pharmaceutical-sciences.1281

By:

PAWAR, SWARANJALI;
SHINDE, SHALINI;
CHAVAN, POOJA;
RATHOD, S.;
CHOUDHARI, P.;
ARVINDEKAR, SNEHAL;
PATIL, S.

Publication type:

Article

The driving power of the cell cycle: cyclin-dependent kinases, cyclins and their inhibitors.

Published in:

Bratislava Medical Journal / Bratislavské Lekárske Listy, 2023, v. 124, n. 4, p. 261, doi. 10.4149/BLL_2023_039

By:

HIVES, Mark;
JURECEKOVA, Jana;
HIVES HOLECKOVA, Klaudia;
KLIMENT, Jan;
KMETOVA SIVONOVA, Monika

Publication type:

Article

Cyclin-Dependent Kinase Inhibitors KRP1 and KRP2 Are Involved in Grain Filling and Seed Germination in Rice (Oryza sativa L.).

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 245, doi. 10.3390/ijms21010245

By:

Ajadi, Abolore Adijat;
Tong, Xiaohong;
Wang, Huimei;
Zhao, Juan;
Tang, Liqun;
Li, Zhiyong;
Liu, Xixi;
Shu, Yazhou;
Li, Shufan;
Wang, Shuang;
Liu, Wanning;
Tajo, Sani Muhammad;
Zhang, Jian;
Wang, Yifeng

Publication type:

Article

Continuing Cyclin-Dependent Kinase 4/6 Inhibitors Beyond Progression in Advanced Breast Cancer: A Meta-Analysis †.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1609, doi. 10.3390/cancers17101609

By:

Pathak, Neha;
Kumar, Sudhir;
Gimenez, Diego Malon;
Di Iorio, Massimo;
Savill, Jacqueline;
Berner-Wygoda, Yael;
Li, Meredith;
Valiente, Consolacion Molto;
Cuthbert, Danielle;
Gupta, Aarushi;
Arteaga, Diana P.;
Batra, Atul;
Amir, Eitan;
Mittal, Abhenil

Publication type:

Article

USE OF CYCLIN-DEPENDENT KINASE 4 AND 6 INHIBITORS IN TREATING METASTATIC BREAST CANCER - A YEAR-LONG EXPERIENCE OF SUBOTICA GENERAL HOSPITAL IN PATIENT FOLLOW-UP.

Published in:

Medical Review / Medicinski Pregled, 2024, v. 77, n. 3/4, p. 94, doi. 10.2298/MPNS2404094B

By:

ZELEN, Teodora BRDAR;
JOVIŠEVIĆ, Marija;
PRICA, Anja

Publication type:

Article

Analyzing the scaffold diversity of cyclin‐dependent kinase inhibitors and revisiting the clinical and preclinical pipeline.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 2, p. 654, doi. 10.1002/med.21856

By:

Bhurta, Deendyal;
Bharate, Sandip B.

Publication type:

Article

Sodium valproate affects the expression of p16INK4a and p21WAFI/Cip1 cyclin‑dependent kinase inhibitors in HeLa cells.

Published in:

Oncology Letters, 2024, v. 28, n. 3, p. N.PAG, doi. 10.3892/ol.2024.14563

By:

Rocha, Marina Amorim;
Cardoso, Adauto Lima;
Martins, Cesar;
Mello, Maria Luiza S.

Publication type:

Article

Interferon-β sensitizes human glioblastoma cells to the cyclin-dependent kinase inhibitor, TG02.

Published in:

Oncology Letters, 2020, v. 19, n. 4, p. 2649, doi. 10.3892/ol.2020.11362

By:

LOHMANN, BIRTHE;
RHUN, EMILIE LE;
SILGINER, MANUELA;
EPSKAMP, MIRKA;
WELLER, MICHAEL

Publication type:

Article

Effect of tumor suppressor gene cyclin-dependent kinase inhibitor 2A wild-type and A148T mutant on the cell cycle of human ovarian cancer cells.

Published in:

Oncology Letters, 2014, v. 7, n. 4, p. 1229, doi. 10.3892/ol.2014.1867

By:

ZEHUA BIAN;
YANG YU;
TERIGELE YANG;
CHAO QUAN;
WENJING SUN;
SONGBIN FU

Publication type:

Article

Effects of cyclin-dependent kinase activity on the coordination of growth and the cell cycle in green algae at different temperatures.

Published in:

Journal of Experimental Botany, 2019, v. 70, n. 3, p. 845, doi. 10.1093/jxb/ery391

By:

Zachleder, Vilém;
Ivanov, Ivan;
Vítová, Milada;
Bišová, Kateřina

Publication type:

Article

Cyclin-dependent kinase inhibitor 2B gene is associated with the sensitivity of hepatoma cells to Sorafenib.

Published in:

OncoTargets & Therapy, 2019, v. 12, p. 5025, doi. 10.2147/OTT.S196607

By:

Weng, Xie;
Zeng, Lixian;
Yan, Feifei;
He, Mengxue;
Wu, Xiuqiong;
Zheng, Dayong

Publication type:

Article

Cyclin-dependent kinase-specific activity predicts the prognosis of stage I and stage II non-small cell lung cancer.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-755

By:

Hiroshi Kubo;
Takashi Suzuki;
Tomoko Matsushima;
Hideki Ishihara;
Kazuya Uchino;
Satoshi Suzuki;
Sachiyo Tada;
Masahiro Yoshimura;
Takashi Kondo

Publication type:

Article

Pulchranin A: First report of isolation from an endophytic fungus and its inhibitory activity on cyclin dependent kinases.

Published in:

Natural Product Research, 2020, v. 34, n. 19, p. 2715, doi. 10.1080/14786419.2019.1585846

By:

Moussa, Ashaimaa Y.;
Mostafa, Nada M.;
Singab, Abdel Nasser B.

Publication type:

Article

Inhibition of cyclin‐dependent kinase activity exacerbates H2O2‐induced DNA damage in Kindler syndrome keratinocytes.

Published in:

Experimental Dermatology, 2019, v. 28, n. 9, p. 1074, doi. 10.1111/exd.14000

By:

Emmert, Hila;
Culley, Jayne;
Brunton, Valerie G.

Publication type:

Article

Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors.

Published in:

Cancer (0008543X), 2015, v. 121, n. 9, p. 1463, doi. 10.1002/cncr.29213

By:

Vaughn, David J.;
Hwang, Wei‐Ting;
Lal, Priti;
Rosen, Mark A.;
Gallagher, Maryann;
O'Dwyer, Peter J.

Publication type:

Article

Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 6, p. 1528, doi. 10.1111/cbdd.12618

By:

Řezníčková, Eva;
Weitensteiner, Sabine;
Havlíček, Libor;
Jorda, Radek;
Gucký, Tomáš;
Berka, Karel;
Bazgier, Václav;
Zahler, Stefan;
Kryštof, Vladimír;
Strnad, Miroslav

Publication type:

Article

Cyclin-dependent kinase 4 and 6 inhibitors in combination with neoadjuvant endocrine therapy in estrogen receptor-positive early breast cancer: a systematic review and meta-analysis.

Published in:

Clinical & Experimental Medicine, 2023, v. 23, n. 2, p. 245, doi. 10.1007/s10238-022-00814-3

By:

Guan, Yumei;
Shen, Guoshuang;
Fang, Qianqian;
Xin, Yuanfang;
Huo, Xingfa;
Li, Jinming;
Zhao, Fuxing;
Ren, Dengfeng;
Liu, Zhen;
Li, Zitao;
Zhao, Jiuda

Publication type:

Article

Acute-on-Chronic Liver Failure Incited by Cyclin-Dependent Kinase Inhibitor Therapy for Breast Cancer Effectively Treated With Liver Transplantation.

Published in:

ACG Case Reports Journal, 2024, v. 11, n. 1, p. 1, doi. 10.14309/crj.0000000000001253

By:

Kalas, Vasilios;
Nguyen, Jessica;
Wan, Alan W.;
Dietch, Zachary C.;
Kulik, Laura;
Hughes, Dempsey L.

Publication type:

Article

Elevated methylation of cyclin dependent kinase inhibitor 2B contributes to the risk of coronary heart disease in women.

Published in:

Experimental & Therapeutic Medicine, 2019, v. 17, n. 1, p. 205

By:

Chen, Xiaomin;
Jiang, Danjie;
Xu, Limin;
Han, Liyuan;
Hu, Haochang;
Huang, Yi;
Lu, Deyi;
Ji, Huihui;
Li, Bin;
Yang, Yong;
Zhou, Cong;
Xu, Xuting;
Wu, Nan;
Xu, Xiaofeng;
Xu, Yan;
Shen, Yusheng;
Li, Jiyi;
Duan, Shiwei

Publication type:

Article

Tailoring advanced breast cancer treatment after cyclin-dependent kinase 4/6 inhibitors progression - real-world data analysis.

Published in:

Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1408664

By:

Kubeczko, Marcin;
Polakiewicz-Gilowska, Anna;
Świderska, Katarzyna;
Leśniak, Aleksandra;
Mianowska-Malec, Marta;
Łanoszka, Barbarba;
Chomik, Konstanty;
Grandys, Barbara;
Lisovska, Natalya;
Bobek-Billewicz, Barbara;
Chmielik, Ewa;
Jarząb, Michał

Publication type:

Article

CANCER THERAPY BY CYCLIN-DEPENDENT KINASE INHIBITORS (CDKIS): BENCH TO BEDSIDE.

Published in:

EXCLI Journal, 2024, v. 23, p. 862, doi. 10.17179/excli2024-7076

By:

Hassanzadeh, Ali;
Shomali, Navid;
Kamrani, Amin;
Soltani-Zangbar, Mohammad Sadegh;
Nasiri, Hadi;
Akbari, Morteza

Publication type:

Article

Studying the mechanism that enables paullones to selectively inhibit glycogen synthase kinase 3 rather than cyclin-dependent kinase 5 by molecular dynamics simulations and free-energy calculations.

Published in:

Journal of Molecular Modeling, 2011, v. 17, n. 4, p. 795, doi. 10.1007/s00894-010-0762-0

By:

Quan Chen;
Wei Cui;
Yuanhua Cheng;
Fushi Zhang;
Mingjuan Ji

Publication type:

Article

Cyclin-Dependent Kinase Inhibitors for the Treatment of Breast Cancer: Past, Present, and Future.

Published in:

Pharmacotherapy, 2016, v. 36, n. 6, p. 652, doi. 10.1002/phar.1756

By:

DiPippo, Adam J.;
Patel, Neelam K.;
Barnett, Chad M.

Publication type:

Article

Anti-cancer therapy with cyclin-dependent kinase inhibitors: impact and challenges.

Published in:

Expert Reviews in Molecular Medicine, 2021, v. 23, p. 1, doi. 10.1017/erm.2021.3

By:

Reinius, Marika A. V.;
Smyth, Elizabeth

Publication type:

Article

Neoadjuvant Therapy of Cyclin-Dependent Kinase 4/6 Inhibitors Combined with Endocrine Therapy in HR+/HER2− Breast Cancer: A Systematic Review and Meta-Analysis.

Published in:

Oncology Research & Treatment, 2021, v. 44, n. 10, p. 557, doi. 10.1159/000518573

By:

Hong, Kai;
Yao, Lingli;
Sheng, Xianneng;
Ye, Dan;
Guo, Yu

Publication type:

Article

Pretreatment neutrophil to lymphocyte ratio as prognostic factor in metastatic breast cancer treated with cyclin dependent kinase 4/6 inhibitors.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2022.1105587

By:

Rottier, Pauline;
Emile, George;
Johnson, Alison;
Levy, Christelle;
Allouache, Djelila;
Hrab, Ioana;
Segura, Carine;
Morel, Adeline;
Villemin, Maud;
Dubot-Poitelon, Coraline;
Boismoreau, Louis;
Cherifi, François;
Lequesne, Justine;
Da Silva, Angélique

Publication type:

Article

Activation of an alfalfa cyclin-dependent kinase inhibitor by calmodulin-like domain protein kinase.

Published in:

Plant Journal, 2006, v. 46, n. 1, p. 111, doi. 10.1111/j.1365-313X.2006.02677.x

By:

Pettkó-Szandtner, Aladár;
Mészáros, Tamás;
Horváth, Gábor V.;
Bak, Lászl;
Csordás-Tóth, Éva;
Blastyák, András;
Zhiponova, Miroslava;
Miskolczi, Pál;
Dudits, Dénes

Publication type:

Article

Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2

Published in:

FEBS Letters, 2003, v. 544, n. 1-3, p. 38, doi. 10.1016/S0014-5793(03)00446-0

By:

Kwun, Hyun Jin;
Lee, Jae Hwa;
Min, Do Sik;
Jang, Kyung Lib

Publication type:

Article

Ultraviolet-B-Induced G1 Arrest is Mediated by Downregulation of Cyclin-Dependent Kinase 4 in Transformed Keratinocytes Lacking Functional p53.

Published in:

Journal of Investigative Dermatology, 2002, v. 118, n. 5, p. 818, doi. 10.1046/j.1523-1747.2002.01734.x

By:

Kim, Arianna L;
Athar, Mohammad;
Bickers, David R;
Gautier, Jean

Publication type:

Article

Turkish cases of early infantile epileptic encephalopathy: two novel mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene.

Published in:

Turkish Journal of Pediatrics, 2015, v. 57, n. 3, p. 272

By:

Gökben, Sarenur;
Serdaroğlu, Gül;
Yılmaz, Sanem;
Bienvenu, Thierry;
Ceylaner, Serdar

Publication type:

Article

Gene polymorphisms of cyclin‐dependent kinase inhibitor and matrix metalloproteinase‐9 in Sudanese patients with esophageal squamous cell carcinoma.

Published in:

Molecular Genetics & Genomic Medicine, 2022, v. 10, n. 12, p. 1, doi. 10.1002/mgg3.2074

By:

Eltayeb, Majdolin Mohammed;
Ali, Mohamed M.;
Omar, Saeed M.;
Mohamed, Nouh Saad;
Adam, Ishag;
Hamdan, Hamdan Z.

Publication type:

Article

Functional characterization of the tomato cyclin-dependent kinase inhibitor SlKRP1 domains involved in protein-protein interactions.

Published in:

New Phytologist, 2010, v. 188, n. 1, p. 136, doi. 10.1111/j.1469-8137.2010.03364.x

By:

Nafati, Mehdi;
Frangne, Nathalie;
Hernould, Michel;
Chevalier, Christian;
Gévaudant, Frédéric

Publication type:

Article

Mechanistic Roles of Transcriptional Cyclin-Dependent Kinases in Oncogenesis: Implications for Cancer Therapy.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1554, doi. 10.3390/cancers17091554

By:

Alrouji, Mohammed;
Alshammari, Mohammed S.;
Anwar, Saleha;
Venkatesan, Kumar;
Shamsi, Anas

Publication type:

Article

Cyclin-Dependent Kinase Inhibition in Prostate Cancer: Past, Present, and Future.

Published in:

Cancers, 2025, v. 17, n. 5, p. 774, doi. 10.3390/cancers17050774

By:

Siskin, Matthew;
Economides, Minas P.;
Wise, David R.

Publication type:

Article

Imidazole-4-N-acetamide Derivatives as a Novel Scaffold for Selective Targeting of Cyclin Dependent Kinases.

Published in:

Cancers, 2023, v. 15, n. 15, p. 3766, doi. 10.3390/cancers15153766

By:

Rusina, Polina;
Gandalipov, Erik;
Abdusheva, Yana;
Panova, Maria;
Burdenkova, Alexandra;
Chaliy, Vasiliy;
Brachs, Maria;
Stroganov, Oleg;
Guzeeva, Ksenia;
Svitanko, Igor;
Shtil, Alexander;
Novikov, Fedor

Publication type:

Article

Opposite Regulation of the Expression of Cyclin-Dependent Kinase Inhibitors during Contact Inhibition1.

Published in:

Journal of Biochemistry, 1999, v. 125, n. 1, p. 36, doi. 10.1093/oxfordjournals.jbchem.a022265

By:

Yanagisawa, Ken;
Kosaka, Akiko;
Iwahana, Hiroyuki;
Nakanishi, Makoto;
Tominaga, Shin-ichi

Publication type:

Article

SKUAMÖZ HÜCRELİ LARİNKS KANSERİNDE p53 MUTASYONU VE p21 SİKLİN BAĞIMLI KİNAZ İNHİBİTÖRÜ EKSPRESYONUNUN SAĞKAUM VE PROGNOSTİK FAKTÖRLERLE İLİŞKİSİ.

Published in:

Nobel Medicus Journal, 2014, v. 10, n. 1, p. 68

By:

Salman, Nergis;
Akın, İstemihan;
Hücümenoğlu, Sema

Publication type:

Article

Adjuvant cyclin‐dependent kinase 4/6 inhibition in hormone receptor–positive breast cancer: One Monarch to rule them all?

Published in:

Cancer (0008543X), 2021, v. 127, n. 18, p. 3302, doi. 10.1002/cncr.33650

By:

Dhakal, Ajay;
Falkson, Carla;
O'Regan, Ruth M.

Publication type:

Article

A cyclin-dependent kinase family member (PHOA) is required to link developmental fate to environmental conditions in Aspergillus nidulans.

Published in:

EMBO Journal, 1998, v. 17, n. 14, p. 3990, doi. 10.1093/emboj/17.14.3990

By:

Business, Henk-Jan;
Osmani, Stephen A.

Publication type:

Article

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2220, doi. 10.3390/molecules25092220

By:

Abdalla, Ashraf N.;
Abdallah, Mohamed E.;
Aslam, Akhmed;
Bader, Ammar;
Vassallo, Antonio;
Tommasi, Nunziatina De;
Malki, Waleed H.;
Gouda, Ahmed M.;
Mukhtar, Mohammed H.;
El-Readi, Mahmoud Zaki;
Alkahtani, Hamad M.;
Abdel-Aziz, Alaa A.-M.;
El-Azab, Adel S.;
Tylkowski, Bartosz;
Bajek, Anna;
Roszkowski, Krzysztof

Publication type:

Article

Identification of High-Affinity Inhibitors of Cyclin-Dependent Kinase 2 Towards Anticancer Therapy.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4589, doi. 10.3390/molecules24244589

By:

Mohammad, Taj;
Batra, Sagar;
Dahiya, Rashmi;
Baig, Mohammad Hassan;
Rather, Irfan Ahmad;
Dong, Jae-June;
Hassan, Imtaiyaz;
Tylkowski, Bartosz

Publication type:

Article

Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.757120

By:

Thoma, Oana-Maria;
Neurath, Markus F.;
Waldner, Maximilian J.

Publication type:

Article

Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.757120

By:

Thoma, Oana-Maria;
Neurath, Markus F.;
Waldner, Maximilan J.

Publication type:

Article

MYC Upregulation Confers Resistance to Everolimus and Establishes Vulnerability to Cyclin-Dependent Kinase Inhibitors in Pancreatic Neuroendocrine Neoplasm Cells.

Published in:

Neuroendocrinology, 2021, v. 111, n. 8, p. 739, doi. 10.1159/000509865

By:

Terracciano, Francesca;
Capone, Alessia;
Montori, Andrea;
Rinzivillo, Maria;
Partelli, Stefano;
Panzuto, Francesco;
Pilozzi, Emanuela;
Arcidiacono, Paolo Giorgio;
Sette, Claudio;
Capurso, Gabriele

Publication type:

Article

A current and comprehensive review of cyclin-dependent kinase inhibitors for the treatment of metastatic breast cancer.

Published in:

2017

By:

Bilgin, Burak;
Sendur, Mehmet A.N.;
Şener Dede, Didem;
Akıncı, Muhammed Bülent;
Yalçın, Bülent;
Şener Dede, Didem;
Akıncı, Muhammed Bülent;
Yalçın, Bülent

Publication type:

journal article

Cyclin-Dependent Kinase Inhibitor 2A is a Key Regulator of Cell Cycle Arrest and Senescence in Endothelial Colony-Forming Cells in Moyamoya Disease.

Published in:

Journal of Korean Neurosurgical Society, 2023, v. 66, n. 6, p. 662, doi. 10.3340/jkns.2023.0005

By:

Seung Ah Choi;
Youn Joo Moon;
Eun Jung Koh;
Ji Hoon Phi;
Ji Yeoun Lee;
Kyung Hyun Kim;
Seung-Ki Kim

Publication type:

Article

Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis

Published in:

FEBS Letters, 2009, v. 583, n. 6, p. 971, doi. 10.1016/j.febslet.2009.02.028

By:

Shi, Jiaqi;
Hershey, John W.B.;
Nelson, Mark A.

Publication type:

Article

Retinal and Peripheral Nerve Toxicity Induced by the Administration of a Pan-Cyclin Dependent Kinase (cdk) Inhibitor in Mice.

Published in:

Toxicologic Pathology, 2006, v. 34, n. 3, p. 243, doi. 10.1080/01926230600713186

By:

Illanes, Oscar;
Anderson, Scott;
Niesman, Michael;
Zwick, Laura;
Jessen, Bart A.

Publication type:

Article

Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury.

Published in:

Journal of Neurochemistry, 2016, v. 138, n. 2, p. 317, doi. 10.1111/jnc.13620

By:

Yousuf, Mohammad A.;
Tan, Chunfeng;
Torres‐Altoro, Melissa I.;
Lu, Fang‐Min;
Plautz, Erik;
Zhang, Shanrong;
Takahashi, Masaya;
Hernandez, Adan;
Kernie, Steven G.;
Plattner, Florian;
Bibb, James A.

Publication type:

Article

The effect of Cyclin-dependent kinase 5 on voltage-dependent calcium channels in PC12 cells varies according to channel type and cell differentiation state.

Published in:

Journal of Neurochemistry, 2014, v. 130, n. 4, p. 498, doi. 10.1111/jnc.12746

By:

Furusawa, Kotaro;
Asada, Akiko;
Saito, Taro;
Hisanaga, Shin‐ichi

Publication type:

Article