Works matching Bone pain and cancer

Results: 850

鞘内注射Akt特异性抑制剂GSK690693 抑制骨癌诱导的大鼠痛相关行为的研究.

Published in:

Progress in Modern Biomedicine, 2017, v. 17, n. 25, p. 4812, doi. 10.13241/j.cnki.pmb.2017.25.003

By:

廖志军;
周云龙;
李静;
梁洪享;
袁翠堂;
丁罡

Publication type:

Article

BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1575733

By:

Xie, Mingming;
Li, Dan;
Zeng, Haohao;
Huang, Yulin;
Xu, Rui;
Wang, Zhen;
Yu, Jiacheng;
Sun, Yu'e

Publication type:

Article

Oxytocin ameliorates bone cancer pain by suppressing toll-like receptor 4 and proinflammatory cytokines in rat spinal cord.

Published in:

Journal of Neurogenetics, 2020, v. 34, n. 2, p. 216, doi. 10.1080/01677063.2019.1711077

By:

Mou, Xiaping;
Fang, Ji;
Yang, An;
Du, Gang

Publication type:

Article

微小 RNA-362 通过调控组蛋白去乙酰化酶 6 抑制大鼠骨癌痛.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2021, v. 42, n. 5, p. 706, doi. 10.7652/jdyxb202105011

By:

郭池华;
王湘;
刘焕;
赵妍;
郭玉芳;
王爽;
王文涛

Publication type:

Article

TET1-TRPV4 Signaling Contributes to Bone Cancer Pain in Rats.

Published in:

Brain Sciences (2076-3425), 2023, v. 13, n. 4, p. 644, doi. 10.3390/brainsci13040644

By:

Xu, Zhen-Hua;
Niu, Zheng;
Liu, Yun;
Liu, Pei-Lin;
Lin, Xiao-Long;
Zhang, Ling;
Chen, Long;
Song, Yu;
Sun, Ren;
Zhang, Hai-Long

Publication type:

Article

Resolvin D2 Reduces Chronic Neuropathic Pain and Bone Cancer Pain via Spinal Inhibition of IL-17 Secretion, CXCL1 Release and Astrocyte Activation in Mice.

Published in:

Brain Sciences (2076-3425), 2023, v. 13, n. 1, p. 152, doi. 10.3390/brainsci13010152

By:

Pang, Jun;
Xin, Pengfei;
Kong, Ying;
Wang, Zhe;
Wang, Xiaopeng

Publication type:

Article

Simultaneous inhibition of NMDA and mGlu1/5 receptors by levo-corydalmine in rat spinal cord attenuates bone cancer pain.

Published in:

International Journal of Cancer, 2017, v. 141, n. 4, p. 805, doi. 10.1002/ijc.30780

By:

Dai, Wen‐Ling;
Yan, Bing;
Jiang, Nan;
Wu, Juan‐Juan;
Liu, Xiu‐Feng;
Liu, Ji‐Hua;
Yu, Bo‐Yang

Publication type:

Article

Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain.

Published in:

International Journal of Cancer, 2017, v. 140, n. 2, p. 411, doi. 10.1002/ijc.30438

By:

Ding, Zhuofeng;
Xu, Wei;
Zhang, Jie;
Zou, Wangyuan;
Guo, Qulian;
Huang, Changsheng;
Liu, Chang;
Zhong, Tao;
Zhang, Jun‐Ming;
Song, Zongbin

Publication type:

Article

Bone Pain in Cancer Patients: Mechanisms and Current Treatment.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 23, p. 6047, doi. 10.3390/ijms20236047

By:

Zajączkowska, Renata;
Kocot-Kępska, Magdalena;
Leppert, Wojciech;
Wordliczek, Jerzy

Publication type:

Article

Targeted therapy: P2X3 receptor silencing in bone cancer pain relief.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 11, p. 1, doi. 10.1002/jbt.70026

By:

Jiang, Yuge;
Liu, Xuan;
Zhang, Hong;
Xu, Longhe

Publication type:

Article

Management of cancer pain due to bone metastasis.

Published in:

Journal of Bone & Mineral Metabolism, 2023, v. 41, n. 3, p. 327, doi. 10.1007/s00774-022-01382-y

By:

Takei, Daisuke;
Tagami, Keita

Publication type:

Article

Down-Regulation of NOX4 Expression in Dorsal Horn of Spinal Cord Could Alleviate Cancer-Induced Bone Pain in Rats by Reducing Oxidative Stress Response.

Published in:

Cancer Management & Research, 2020, v. 12, p. 10929, doi. 10.2147/CMAR.S263177

By:

Long, Hao;
Zheng, Hui;
Ai, Long;
Osman, Kamil;
Liu, Zhigang

Publication type:

Article

Effect of bushen tongluo decoction on the ERK/c-Fos signal transduction pathway in rats with bone cancer pain.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2023, v. 36, p. 1859, doi. 10.36721/PJPS.2023.36.6.SP.1859-1867.1

By:

Xinchao Jiang;
Yi Song;
Mei Fang;
Biao Zhang;
Yinyin Guo;
Zhijun Fang;
Jianxue Qian

Publication type:

Article

Scutellarin Mitigates Cancer-Induced Bone Pain by Suppressing CaMKII/CREB Pathway in Rat Models.

Published in:

Current Topics in Nutraceutical Research, 2019, v. 17, n. 3, p. 249, doi. 10.37290/ctnr2641-452x.17:249-253

By:

Chenglong Liu;
Haihua Liu;
Fei Zhang;
Jie Zheng;
Fang Wei

Publication type:

Article

Delayed Activation of Spinal Microglia Contributes to the Maintenance of Bone Cancer Pain in Female Wistar Rats via P2X7 Receptor and IL-18.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 20, p. 7950, doi. 10.1523/JNEUROSCI.5250-14.2015

By:

Yan Yang;
Hui Li;
Ting-Ting Li;
Hao Luo;
Xi-Yao Gu;
Ning Lü;
Ru-Rong Ji;
Yu-Qiu Zhang

Publication type:

Article

Effects of dezocine on morphine tolerance and opioid receptor expression in a rat model of bone cancer pain.

Published in:

2021

By:

Wu, Lin-xin;
Dong, Yan-peng;
Zhu, Qian-mei;
Zhang, Bo;
Ai, Bo-lun;
Yan, Tao;
Zhang, Guo-hua;
Sun, Li

Publication type:

journal article

Esketamine inhibits the c-Jun N-terminal kinase pathway in the spinal dorsal horn to relieve bone cancer pain in rats.

Published in:

Molecular Pain, 2024, p. 1, doi. 10.1177/17448069241239231

By:

Duan, Chenxia;
Zhu, Yi;
Zhang, Zhuoliang;
Wu, Tiantian;
Shen, Mengwei;
Xu, Jinfu;
Gao, Wenxin;
Pan, Jianhua;
Wei, Lei;
Su, Huibin;
Shi, Chenghuan

Publication type:

Article

AAV-mediated siRNA against TRPV1 reduces nociception in a rat model of bone cancer pain.

Published in:

Neurological Research, 2019, v. 41, n. 11, p. 972, doi. 10.1080/01616412.2019.1639317

By:

Zhang, Shuangli;
Zhao, Jun;
Meng, Qinggang

Publication type:

Article

Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn.

Published in:

Integrative Cancer Therapies, 2021, v. 20, p. 1, doi. 10.1177/1534735421995237

By:

Jiang, Bin;
Zhong, Xuemei;
Fang, Junfan;
Zhang, Aijun;
WangD, Wen;
Liang, Yi;
Fang, Jianqiao;
Chen, Feng;
Du, Junying

Publication type:

Article

Expression of Synaptic Proteins in the DRGs and Spinal Cord in Rats with Bone Cancer Pain.

Published in:

Neurophysiology, 2019, v. 51, n. 1, p. 9, doi. 10.1007/s11062-019-09784-x

By:

Xie, X.;
Li, X.;
Zhao, H.;
Li, Y.;
Gao, Y.;
Xu, X.;
Wang, H.;
Zhang, X.;
Ke, Ch.

Publication type:

Article

Monocyte chemoattractant protein-1 contributes to morphine tolerance in rats with cancer-induced bone pain.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 13, n. 2, p. 461, doi. 10.3892/etm.2016.3979

By:

LEI LIU;
XIU-JUAN GAO;
CHUN-GUANG REN;
JI-HUA HU;
XIAN-WEN LIU;
PING ZHANG;
ZONG-WANG ZHANG;
ZHI-JIAN FU

Publication type:

Article

Effect of systemic injection of heterogenous and homogenous opioids on peripheral cellular immune response in rats with bone cancer pain: A comparative study.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 12, n. 4, p. 2568, doi. 10.3892/etm.2016.3647

By:

JUN-YING DU;
YI LIANG;
JUN-FAN FANG;
YONG-LIANG JIANG;
XIAO-MEI SHAO;
XIAO-FEN HE;
JIAN-QIAO FANG

Publication type:

Article

siRNA-mediated downregulation of GluN2B in the rostral anterior cingulate cortex attenuates mechanical allodynia and thermal hyperalgesia in a rat model of pain associated with bone cancer.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 11, n. 1, p. 221, doi. 10.3892/etm.2015.2859

By:

YONGGUANG XU;
GONGMING WANG;
XULI ZOU;
ZAIQI YANG;
QIN WANG;
HAO FENG;
MENGYUAN ZHANG

Publication type:

Article

Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism.

Published in:

Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.696861

By:

Zhao, Guanghai;
Shi, Yongqiang;
Gong, Chaoyang;
Liu, Taicong;
Nan, Wei;
Ma, Lin;
Wu, Zuolong;
Da, Chaoming;
Zhou, Kaisheng;
Zhang, Haihong

Publication type:

Article

Chemokine receptor CXCR4 activates the RhoA/ROCK2 pathway in spinal neurons that induces bone cancer pain.

Published in:

Molecular Pain, 2020, v. 16, p. 1, doi. 10.1177/1744806920919568

By:

Xu, Heng;
Peng, Chong;
Chen, Xue-Tai;
Yao, Ying-Ying;
Chen, Li-Ping;
Yin, Qin;
Shen, Wen

Publication type:

Article

Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.

Published in:

Molecular Pain, 2020, v. 16, p. 1, doi. 10.1177/1744806920909993

By:

Yu, Jiachuan;
Luo, Yuanyuan;
Jin, Huidan;
Lv, Jiaxin;
Zhou, Tingting;
Yabasin, Iddrisu Baba;
Wen, Qingping

Publication type:

Article

BI4 ameliorates bone cancer pain through downregulating spinal interleukin-1β via suppressing neuron JAK2/STAT3 pathway.

Published in:

Molecular Pain, 2019, v. 15, p. 1, doi. 10.1177/1744806919886498

By:

Miao Xu;
Huadong Ni;
Longsheng Xu;
Hui Shen;
Housheng Deng;
Yungong Wang;
Ming Yao

Publication type:

Article

Endoplasmic reticulum stress promoting caspase signaling pathway-dependent apoptosis contributes to bone cancer pain in the spinal dorsal horn.

Published in:

Molecular Pain, 2019, v. 15, p. 1, doi. 10.1177/1744806919876150

By:

Qiuli He;
Tingting Wang;
Huadong Ni;
Qianying Liu;
Kang An;
Jiachun Tao;
Yajing Chen;
Longsheng Xu;
Chunyan Zhu;
Ming Yao

Publication type:

Article

2-Bromopalmitate attenuates bone cancer pain via reversing mitochondrial fusion and fission imbalance in spinal astrocytes.

Published in:

Molecular Pain, 2019, v. 15, p. 1, doi. 10.1177/1744806919871813

By:

Wei Meng;
Miao-Miao Hao;
Na Yu;
Ming-Yue Li;
Jie-Qiong Ding;
Bang-Hua Wang;
Hai-Li Zhu;
Min Xie

Publication type:

Article

Promotion of bone cancer pain development by decorin is accompanied by modification of excitatory synaptic molecules in the spinal cord.

Published in:

Molecular Pain, 2019, v. 15, p. 1, doi. 10.1177/1744806919864253

By:

Huan Wang;
Xiaohui Li;
Xianqiao Xie;
Haiwen Zhao;
Yan Gao;
Yang Li;
Xueqin Xu;
Xiaofei Zhang;
Changbin Ke;
Juying Liu

Publication type:

Article

Amitriptyline influences the mechanical withdrawal threshold in bone cancer pain rats by regulating glutamate transporter GLAST.

Published in:

Molecular Pain, 2019, v. 15, p. 1, doi. 10.1177/1744806919855834

By:

Simeng Ma;
Xiaochun Zheng;
Ting Zheng;
Fengyi Huang;
Jundan Jiang;
Huirong Luo;
Qianqian Guo;
Bin Hu

Publication type:

Article

Upregulation of bone morphogenetic protein 2 (Bmp2) in dorsal root ganglion in a rat model of bone cancer pain.

Published in:

Molecular Pain, 2019, v. 15, p. 1, doi. 10.1177/1744806918824250

By:

Wei Wang;
Qiliang Jiang;
Jingxiang Wu;
Wei Tang;
Meiying Xu

Publication type:

Article

Activation of the P2X7 receptor in midbrain periaqueductal gray participates in the analgesic effect of tramadol in bone cancer pain rats.

Published in:

Molecular Pain, 2018, v. 14, p. 1, doi. 10.1177/1744806918803039

By:

Pengtao Li;
Quan Zhang;
Zhi Xiao;
Shouyang Yu;
Yan Yan;
Ying Qin

Publication type:

Article

Sinomenine attenuates cancer-induced bone pain via suppressing microglial JAK2/STAT3 and neuronal CAMKII/CREB cascades in rat models.

Published in:

Molecular Pain, 2018, v. 14, p. 1, doi. 10.1177/1744806918793232

By:

Shu-Ping Chen;
Jia Sun;
Ya-Qun Zhou;
Fei Cao;
Braun, Cody;
Fang Luo;
Da-Wei Ye;
Yu-Ke Tian

Publication type:

Article

Dehydrocorydaline attenuates bone cancer pain by shifting microglial M1/M2 polarization toward the M2 phenotype.

Published in:

Molecular Pain, 2018, v. 14, p. 1, doi. 10.1177/1744806918781733

By:

Wenwen Huo;
Ying Zhang;
Yue Liu;
Yishan Lei;
Rao Sun;
Wei Zhang;
Yulin Huang;
Yanting Mao;
Chenchen Wang;
Zhengliang Ma;
Xiaoping Gu

Publication type:

Article

Hedgehog signaling contributes to bone cancer pain by regulating sensory neuron excitability in rats.

Published in:

Molecular Pain, 2018, v. 14, p. 1, doi. 10.1177/1744806918767560

By:

Su Liu;
You Lv;
Xin-Xin Wan;
Zhi-Jing Song;
Yue-Peng Liu;
Shuai Miao;
Guang-Lei Wang;
Gong-Jian Liu

Publication type:

Article

Suppression of asparaginyl endopeptidase attenuates breast cancer-induced bone pain through inhibition of neurotrophin receptors.

Published in:

Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917708127

By:

Peng Yao;
Yuanyuan Ding;
Zhenkai Han;
Ying Mu;
Tao Hong;
Yongqiang Zhu;
Hongxi Li

Publication type:

Article

The Stage-Specific Plasticity of Descending Modulatory Controls in a Rodent Model of Cancer-Induced Bone Pain.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3286, doi. 10.3390/cancers12113286

By:

Kucharczyk, Mateusz Wojciech;
Derrien, Diane;
Dickenson, Anthony Henry;
Bannister, Kirsty

Publication type:

Article

Modulation of Rat Cancer-Induced Bone Pain is Independent of Spinal Microglia Activity.

Published in:

Cancers, 2020, v. 12, n. 10, p. 2740, doi. 10.3390/cancers12102740

By:

Diaz-delCastillo, Marta;
Hansen, Rie Bager;
Appel, Camilla Kristine;
Nielsen, Lykke;
Nielsen, Sascha Nolsøe;
Karyniotakis, Konstantinos;
Dahl, Louise M.;
Andreasen, Rikke B.;
Heegaard, Anne-Marie

Publication type:

Article

The Ubiquitination of Spinal MrgC Alleviates Bone Cancer Pain and Reduces Intracellular Calcium Concentration in Spinal Neurons in Mice.

Published in:

Neurochemical Research, 2019, v. 44, n. 11, p. 2527, doi. 10.1007/s11064-019-02869-3

By:

Sun, Yu-E;
Xu, Hua-Ye;
Hao, Jing;
Huo, Wen-Wen;
Qian, Yue;
Hou, Bai-Ling

Publication type:

Article

Connexin 43 Mediates CXCL12 Production from Spinal Dorsal Horn to Maintain Bone Cancer Pain in Rats.

Published in:

Neurochemical Research, 2016, v. 41, n. 5, p. 1200, doi. 10.1007/s11064-015-1815-7

By:

Hang, Li-Hua;
Li, Shu-Na;
Luo, Hong;
Shu, Wei-Wei;
Mao, Zu-Min;
Chen, Yuan-Feng;
Shi, Lei-Lei;
Shao, Dong-Hua

Publication type:

Article

The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells.

Published in:

2017

By:

Xiao-Fan Hu;
Xiao-Tao He;
Kai-Xiang Zhou;
Chen Zhang;
Wen-Jun Zhao;
Ting Zhang;
Jin-Lian Li;
Jian-Ping Deng;
Yu-Lin Dong;
Hu, Xiao-Fan;
He, Xiao-Tao;
Zhou, Kai-Xiang;
Zhang, Chen;
Zhao, Wen-Jun;
Zhang, Ting;
Li, Jin-Lian;
Deng, Jian-Ping;
Dong, Yu-Lin

Publication type:

journal article

Analgesic effects of adenylyl cyclase inhibitor NB001 on bone cancer pain in a mouse model.

Published in:

Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916652409

By:

Kang, Wen-bo;
Yang, Qi;
Guo, Yan-yan;
Wang, Lu;
Wang, Dong-sheng;
Cheng, Qiang;
Li, Xiao-ming;
Tang, Jun;
Zhao, Jian-ning;
Liu, Gang;
Zhuo, Min;
Zhao, Ming-gao

Publication type:

Article

Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.

Published in:

Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916644929

By:

Wu, Jing-xiang;
Yuan, Xiao-min;
Wang, Qiong;
Wei, Wang;
Xu, Mei-ying

Publication type:

Article

Impacts of anti-nerve growth factor antibody on pain-related behaviors and expressions of opioid receptor in spinal dorsal horn and dorsal root ganglia of rats with cancer-induced bone pain.

Published in:

Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916644928

By:

Yao, Peng;
Ding, Yuanyuan;
Wang, Zhibin;
Ma, Jiaming;
Hong, Tao;
Zhu, Yongqiang;
Li, Hongxi;
Pan, Shinong

Publication type:

Article

Effects of Src-kinase inhibition in cancer-induced bone pain.

Published in:

Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916643725

By:

De Felice, Milena;
Lambert, Daniel;
Holen, Ingunn;
Escott, K Jane;
Andrew, David

Publication type:

Article

CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice.

Published in:

Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916641679

By:

Liang, Ying;
Liu, Yue;
Hou, Bailing;
Zhang, Wei;
Liu, Ming;
Sun, Yu-E;
Ma, Zhengliang;
Gu, Xiaoping

Publication type:

Article

Analgesic effects of adenylyl cyclase inhibitor NB001 on bone cancer pain in a mouse model.

Published in:

Molecular Pain, 2016, v. 12, p. 1, doi. 10.1177/1744806916652409

By:

Wen-bo Kang;
Qi Yang;
Yan-yan Guo;
Lu Wang;
Dong-sheng Wang;
Qiang Cheng;
Xiao-ming Li;
Jun Tang;
Jian-ning Zhao;
Gang Liu;
Min Zhuo;
Ming-gao Zhao

Publication type:

Article

Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.

Published in:

Molecular Pain, 2016, v. 12, p. 1, doi. 10.1177/1744806916644929

By:

Jing-xiang Wu;
Xiao-min Yuan;
Qiong Wang;
Wang Wei;
Mei-ying Xu

Publication type:

Article

Impacts of anti-nerve growth factor antibody on pain-related behaviors and expressions of opioid receptor in spinal dorsal horn and dorsal root ganglia of rats with cancer-induced bone pain.

Published in:

Molecular Pain, 2016, v. 12, p. 1, doi. 10.1177/1744806916644928

By:

Peng Yao;
Yuanyuan Ding;
Zhibin Wang;
Jiaming Ma;
Tao Hong;
Yongqiang Zhu;
Hongxi Li;
Shinong Pan

Publication type:

Article