Works matching Bone pain and cancer

Results: 863

鞘内注射Akt特异性抑制剂GSK690693 抑制骨癌诱导的大鼠痛相关行为的研究.

Published in:

Progress in Modern Biomedicine, 2017, v. 17, n. 25, p. 4812, doi. 10.13241/j.cnki.pmb.2017.25.003

By:

廖志军;
周云龙;
李静;
梁洪享;
袁翠堂;
丁罡

Publication type:

Article

地舒单抗对骨癌痛大鼠痛阈值、凝血功能及 TAK1/JNK/c-Jun 活性的影响.

Published in:

Guangdong Medical Journal, 2025, v. 46, n. 4, p. 519, doi. 10.13820/j.cnki.gdyx.20241992

By:

段登科;
白智龙;
温振涛;
王岩;
孙邦建

Publication type:

Article

Administration of 2-deoxy-D-glucose alleviates cancer-induced bone pain by suppressing microglial polarization to the M1 phenotype and neuroinflammation.

Published in:

Molecular Pain, 2025, v. 21, p. 1, doi. 10.1177/17448069251348778

By:

Liu, Lin;
Li, Dan-Yang;
Zhang, Long-Qing;
Gao, Shao-Jie;
Song, Fan-He;
Wu, Jia-Yi;
Zhou, Ya-Qun;
Liu, Dai-Qiang;
Mei, Wei

Publication type:

Article

Contributions of spinal d-amino acid oxidase to bone cancer pain.

Published in:

Amino Acids, 2012, v. 43, n. 5, p. 1905, doi. 10.1007/s00726-012-1390-z

By:

Huang, Jin-Lu;
Chen, Xiao-Ling;
Guo, Cheng;
Wang, Yong-Xiang

Publication type:

Article

Oxytocin ameliorates bone cancer pain by suppressing toll-like receptor 4 and proinflammatory cytokines in rat spinal cord.

Published in:

Journal of Neurogenetics, 2020, v. 34, n. 2, p. 216, doi. 10.1080/01677063.2019.1711077

By:

Mou, Xiaping;
Fang, Ji;
Yang, An;
Du, Gang

Publication type:

Article

A Single Intrathecal or Intraperitoneal Injection of CB2 Receptor Agonist Attenuates Bone Cancer Pain and Induces a Time-Dependent Modification of GRK2.

Published in:

Cellular & Molecular Neurobiology, 2017, v. 37, n. 1, p. 101, doi. 10.1007/s10571-016-0349-0

By:

Lu, Cui'e;
Shi, Linyu;
Sun, Bei;
Zhang, Yu;
Hou, Bailing;
Sun, Yu'e;
Ma, Zhengliang;
Gu, Xiaoping

Publication type:

Article

Inhibition of HDAC6 alleviates cancer-induced bone pain by reducing the activation of NLRP3 inflammasome.

Published in:

International Journal of Molecular Medicine, 2024, v. 53, n. 1, p. N.PAG, doi. 10.3892/ijmm.2023.5328

By:

Hu, Yin-Di;
Wang, Zhao-Di;
Yue, Yuan-Fen;
Li, Dai;
Zhen, Shu-Qing;
Ding, Jie-Qiong;
Meng, Wei;
Zhu, Hai-Li;
Xie, Min;
Liu, Ling

Publication type:

Article

Activation of the STING pathway induces peripheral sensitization via neuroinflammation in a rat model of bone cancer pain.

Published in:

Inflammation Research, 2023, v. 72, n. 1, p. 117, doi. 10.1007/s00011-022-01663-2

By:

Zhang, Yuxin;
Wang, Wei;
Gong, Zhihao;
Peng, Yuan;
Li, Xin;
Zhang, Zuojing;
Zhang, Xiaoxuan;
You, Xingji;
Wu, Jingxiang

Publication type:

Article

TET1-TRPV4 Signaling Contributes to Bone Cancer Pain in Rats.

Published in:

Brain Sciences (2076-3425), 2023, v. 13, n. 4, p. 644, doi. 10.3390/brainsci13040644

By:

Xu, Zhen-Hua;
Niu, Zheng;
Liu, Yun;
Liu, Pei-Lin;
Lin, Xiao-Long;
Zhang, Ling;
Chen, Long;
Song, Yu;
Sun, Ren;
Zhang, Hai-Long

Publication type:

Article

Resolvin D2 Reduces Chronic Neuropathic Pain and Bone Cancer Pain via Spinal Inhibition of IL-17 Secretion, CXCL1 Release and Astrocyte Activation in Mice.

Published in:

Brain Sciences (2076-3425), 2023, v. 13, n. 1, p. 152, doi. 10.3390/brainsci13010152

By:

Pang, Jun;
Xin, Pengfei;
Kong, Ying;
Wang, Zhe;
Wang, Xiaopeng

Publication type:

Article

Esketamine inhibits the c-Jun N-terminal kinase pathway in the spinal dorsal horn to relieve bone cancer pain in rats.

Published in:

Molecular Pain, 2024, p. 1, doi. 10.1177/17448069241239231

By:

Duan, Chenxia;
Zhu, Yi;
Zhang, Zhuoliang;
Wu, Tiantian;
Shen, Mengwei;
Xu, Jinfu;
Gao, Wenxin;
Pan, Jianhua;
Wei, Lei;
Su, Huibin;
Shi, Chenghuan

Publication type:

Article

AAV-mediated siRNA against TRPV1 reduces nociception in a rat model of bone cancer pain.

Published in:

Neurological Research, 2019, v. 41, n. 11, p. 972, doi. 10.1080/01616412.2019.1639317

By:

Zhang, Shuangli;
Zhao, Jun;
Meng, Qinggang

Publication type:

Article

Monocyte chemoattractant protein-1 contributes to morphine tolerance in rats with cancer-induced bone pain.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 13, n. 2, p. 461, doi. 10.3892/etm.2016.3979

By:

LEI LIU;
XIU-JUAN GAO;
CHUN-GUANG REN;
JI-HUA HU;
XIAN-WEN LIU;
PING ZHANG;
ZONG-WANG ZHANG;
ZHI-JIAN FU

Publication type:

Article

Effect of systemic injection of heterogenous and homogenous opioids on peripheral cellular immune response in rats with bone cancer pain: A comparative study.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 12, n. 4, p. 2568, doi. 10.3892/etm.2016.3647

By:

JUN-YING DU;
YI LIANG;
JUN-FAN FANG;
YONG-LIANG JIANG;
XIAO-MEI SHAO;
XIAO-FEN HE;
JIAN-QIAO FANG

Publication type:

Article

siRNA-mediated downregulation of GluN2B in the rostral anterior cingulate cortex attenuates mechanical allodynia and thermal hyperalgesia in a rat model of pain associated with bone cancer.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 11, n. 1, p. 221, doi. 10.3892/etm.2015.2859

By:

YONGGUANG XU;
GONGMING WANG;
XULI ZOU;
ZAIQI YANG;
QIN WANG;
HAO FENG;
MENGYUAN ZHANG

Publication type:

Article

Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism.

Published in:

Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.696861

By:

Zhao, Guanghai;
Shi, Yongqiang;
Gong, Chaoyang;
Liu, Taicong;
Nan, Wei;
Ma, Lin;
Wu, Zuolong;
Da, Chaoming;
Zhou, Kaisheng;
Zhang, Haihong

Publication type:

Article

Delayed Activation of Spinal Microglia Contributes to the Maintenance of Bone Cancer Pain in Female Wistar Rats via P2X7 Receptor and IL-18.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 20, p. 7950, doi. 10.1523/JNEUROSCI.5250-14.2015

By:

Yan Yang;
Hui Li;
Ting-Ting Li;
Hao Luo;
Xi-Yao Gu;
Ning Lü;
Ru-Rong Ji;
Yu-Qiu Zhang

Publication type:

Article

Management of cancer pain due to bone metastasis.

Published in:

Journal of Bone & Mineral Metabolism, 2023, v. 41, n. 3, p. 327, doi. 10.1007/s00774-022-01382-y

By:

Takei, Daisuke;
Tagami, Keita

Publication type:

Article

微小 RNA-362 通过调控组蛋白去乙酰化酶 6 抑制大鼠骨癌痛.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2021, v. 42, n. 5, p. 706, doi. 10.7652/jdyxb202105011

By:

郭池华;
王湘;
刘焕;
赵妍;
郭玉芳;
王爽;
王文涛

Publication type:

Article

Simultaneous inhibition of NMDA and mGlu1/5 receptors by levo-corydalmine in rat spinal cord attenuates bone cancer pain.

Published in:

International Journal of Cancer, 2017, v. 141, n. 4, p. 805, doi. 10.1002/ijc.30780

By:

Dai, Wen‐Ling;
Yan, Bing;
Jiang, Nan;
Wu, Juan‐Juan;
Liu, Xiu‐Feng;
Liu, Ji‐Hua;
Yu, Bo‐Yang

Publication type:

Article

Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain.

Published in:

International Journal of Cancer, 2017, v. 140, n. 2, p. 411, doi. 10.1002/ijc.30438

By:

Ding, Zhuofeng;
Xu, Wei;
Zhang, Jie;
Zou, Wangyuan;
Guo, Qulian;
Huang, Changsheng;
Liu, Chang;
Zhong, Tao;
Zhang, Jun‐Ming;
Song, Zongbin

Publication type:

Article

Connexin 43 Mediates CXCL12 Production from Spinal Dorsal Horn to Maintain Bone Cancer Pain in Rats.

Published in:

Neurochemical Research, 2016, v. 41, n. 5, p. 1200, doi. 10.1007/s11064-015-1815-7

By:

Hang, Li-Hua;
Li, Shu-Na;
Luo, Hong;
Shu, Wei-Wei;
Mao, Zu-Min;
Chen, Yuan-Feng;
Shi, Lei-Lei;
Shao, Dong-Hua

Publication type:

Article

STING Contributes to Cancer-Induced Bone Pain by Promoting M1 Polarization of Microglia in the Medial Prefrontal Cortex.

Published in:

Cancers, 2022, v. 14, n. 21, p. 5188, doi. 10.3390/cancers14215188

By:

Zhang, Xiaoxuan;
Li, Xin;
Wang, Wei;
Zhang, Yuxin;
Gong, Zhihao;
Peng, Yuan;
Wu, Jingxiang;
You, Xingji

Publication type:

Article

The Stage-Specific Plasticity of Descending Modulatory Controls in a Rodent Model of Cancer-Induced Bone Pain.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3286, doi. 10.3390/cancers12113286

By:

Kucharczyk, Mateusz Wojciech;
Derrien, Diane;
Dickenson, Anthony Henry;
Bannister, Kirsty

Publication type:

Article

Modulation of Rat Cancer-Induced Bone Pain is Independent of Spinal Microglia Activity.

Published in:

Cancers, 2020, v. 12, n. 10, p. 2740, doi. 10.3390/cancers12102740

By:

Diaz-delCastillo, Marta;
Hansen, Rie Bager;
Appel, Camilla Kristine;
Nielsen, Lykke;
Nielsen, Sascha Nolsøe;
Karyniotakis, Konstantinos;
Dahl, Louise M.;
Andreasen, Rikke B.;
Heegaard, Anne-Marie

Publication type:

Article

Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn.

Published in:

Integrative Cancer Therapies, 2021, v. 20, p. 1, doi. 10.1177/1534735421995237

By:

Jiang, Bin;
Zhong, Xuemei;
Fang, Junfan;
Zhang, Aijun;
WangD, Wen;
Liang, Yi;
Fang, Jianqiao;
Chen, Feng;
Du, Junying

Publication type:

Article

Combined application of diclofenac and celecoxib with an opioid yields superior efficacy in metastatic bone cancer pain: a randomized controlled trial.

Published in:

International Journal of Clinical Oncology, 2017, v. 22, n. 5, p. 980, doi. 10.1007/s10147-017-1133-y

By:

Liu, Zunyong;
Xu, Yan;
Liu, Zhong-liang;
Tian, Yi-zhou;
Shen, Xiao-heng

Publication type:

Article

Targeted therapy: P2X3 receptor silencing in bone cancer pain relief.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 11, p. 1, doi. 10.1002/jbt.70026

By:

Jiang, Yuge;
Liu, Xuan;
Zhang, Hong;
Xu, Longhe

Publication type:

Article

Clinical and Genetic Factors Related to Cancer-Induced Bone Pain and Bone Pain Relief.

Published in:

Oncologist, 2014, v. 19, n. 12, p. 1276, doi. 10.1634/theoncologist.2014-0174

By:

Scarpi, Emanuela;
Calistri, Daniele;
Klepstad, Pål;
Kaasa, Stein;
Skorpen, Frank;
Habberstad, Ragnhild;
Nanni, Oriana;
Amadori, Dino;
Maltoni, Marco

Publication type:

Article

Systemic administration of Resolvin D1 reduces cancer‐induced bone pain in mice: Lack of sex dependency in pain development and analgesia.

Published in:

Cancer Medicine, 2024, v. 13, n. 15, p. 1, doi. 10.1002/cam4.70077

By:

Flippen, Alyssa;
Khasabova, Iryna A.;
Simone, Donald A.;
Khasabov, Sergey G.

Publication type:

Article

Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell‐induced bone pain.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2019, v. 46, n. 12, p. 1201, doi. 10.1111/1440-1681.13165

By:

Shenoy, Priyank A.;
Kuo, Andy;
Leparc, German;
Hildebrandt, Tobias;
Rust, Werner;
Nicholson, Janet R.;
Corradini, Laura;
Vetter, Irina;
Smith, Maree T.

Publication type:

Article

Spinal SET7/9 may contribute to the maintenance of cancer-induced bone pain in mice.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2017, v. 44, n. 10, p. 1001, doi. 10.1111/1440-1681.12789

By:

Hang, Li‐Hua;
Xu, Zhen‐Kai;
Wei, Shi‐You;
Shu, Wei‐Wei;
Luo, Hong;
Chen, Jian

Publication type:

Article

Role of nitric oxide synthase in the development of bone cancer pain and effect of L-NMMA.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1220, doi. 10.3892/mmr.2015.4647

By:

YAN YANG;
JUAN ZHANG;
YUE LIU;
YAGUO ZHENG;
JINHUA BO;
XIAOFANG ZHOU;
JUNHUA WANG;
ZHENGLIANG MA

Publication type:

Article

Down-Regulation of NOX4 Expression in Dorsal Horn of Spinal Cord Could Alleviate Cancer-Induced Bone Pain in Rats by Reducing Oxidative Stress Response.

Published in:

Cancer Management & Research, 2020, v. 12, p. 10929, doi. 10.2147/CMAR.S263177

By:

Long, Hao;
Zheng, Hui;
Ai, Long;
Osman, Kamil;
Liu, Zhigang

Publication type:

Article

Preconditioning with hydrogen sulfide prevents bone cancer pain in rats through a proliferator-activated receptor gamma/p38/Jun N-terminal kinase pathway.

Published in:

Experimental Biology & Medicine, 2018, v. 243, n. 1, p. 57, doi. 10.1177/1535370217740859

By:

Zhuang, Li;
Li, Ke;
Wang, Gaowei;
Shou, Tao;
Gao, Chunlin;
Mao, Yong;
Bao, Mingliang;
Zhao, Mingli

Publication type:

Article

Expression of Synaptic Proteins in the DRGs and Spinal Cord in Rats with Bone Cancer Pain.

Published in:

Neurophysiology, 2019, v. 51, n. 1, p. 9, doi. 10.1007/s11062-019-09784-x

By:

Xie, X.;
Li, X.;
Zhao, H.;
Li, Y.;
Gao, Y.;
Xu, X.;
Wang, H.;
Zhang, X.;
Ke, Ch.

Publication type:

Article

Resveratrol attenuates bone cancer pain through the inhibition of spinal glial activation and CX3 CR1 upregulation.

Published in:

Fundamental & Clinical Pharmacology, 2014, v. 28, n. 6, p. 661, doi. 10.1111/fcp.12084

By:

Cheng, Wei;
Zhao, Yu;
Liu, He;
Fan, Qin;
Lu, Fei‐Fei;
Li, Jing;
Yin, Qin;
Yan, Chang‐Dong

Publication type:

Article

Blockade of spinal dopamine D1/D2 receptor heteromers by levo-Corydalmine suppressed calcium signaling cascade in spinal neurons to alleviate bone cancer pain in rats.

Published in:

Journal of Cancer, 2024, v. 15, n. 4, p. 1041, doi. 10.7150/jca.91129

By:

Xiao-Nan Ma;
Chang-Heng Yao;
Yu-Jie Yang;
Xue Li;
Meng-Yuan Zhou;
Jin Yang;
Shen Zhang;
Bo-Yang Yu;
Wen-Ling Dai;
Ji-Hua Liu

Publication type:

Article

Electrical peripheral nerve stimulation relieves bone cancer pain by inducing Arc protein expression in the spinal cord dorsal horn.

Published in:

Journal of Pain Research, 2018, v. 11, p. 599, doi. 10.2147/JPR.S149470

By:

Sun, Ke-fu;
Feng, Wan-wen;
Liu, Yue-peng;
Dong, Yan-bin;
Gao, Li;
Yang, Hui-lin

Publication type:

Article

Up-regulation of brain-derived neurotrophic factor in the dorsal root ganglion of the rat bone cancer pain model.

Published in:

Journal of Pain Research, 2014, v. 7, p. 415, doi. 10.2147/JPR.S63527

By:

Naoto Tomotsuka;
Ryuji Kaku;
Norihiko Obata;
Yoshikazu Matsuoka;
Hirotaka Kanzaki;
Arata Taniguchi;
Noriko Muto;
Hiroki Omiya;
Yoshitaro Itano;
Tadasu Sato;
Hiroyuki Ichikawa;
Satoshi Mizobuchi;
Hiroshi Morimatsu

Publication type:

Article

Transcriptome Sequencing Explores the Mechanism of Baicalin on Bone Cancer Pain.

Published in:

Journal of Inflammation Research, 2021, v. 14, p. 5999, doi. 10.2147/JIR.S336028

By:

Wang, Aitao;
Guo, Dongmei;
Cheng, Hongyu;
Jiang, Hui;
Liu, Xiaojuan;
Yun, Zhizhong

Publication type:

Article

Effect of bushen tongluo decoction on the ERK/c-Fos signal transduction pathway in rats with bone cancer pain.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2023, v. 36, p. 1859, doi. 10.36721/PJPS.2023.36.6.SP.1859-1867.1

By:

Xinchao Jiang;
Yi Song;
Mei Fang;
Biao Zhang;
Yinyin Guo;
Zhijun Fang;
Jianxue Qian

Publication type:

Article

CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord.

Published in:

Journal of Neuroinflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1742-2094-11-75

By:

Wen Shen;
Xue-Ming Hu;
Yan-Nan Liu;
Yuan Han;
Li-Ping Chen;
Chen-Chen Wang;
Chao Song

Publication type:

Article

Effects of dezocine on morphine tolerance and opioid receptor expression in a rat model of bone cancer pain.

Published in:

2021

By:

Wu, Lin-xin;
Dong, Yan-peng;
Zhu, Qian-mei;
Zhang, Bo;
Ai, Bo-lun;
Yan, Tao;
Zhang, Guo-hua;
Sun, Li

Publication type:

journal article

BAM8-22 targets spinal MrgC receptors to modulate UPR<sup>mt</sup> activity in the mechanism of bone cancer pain.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1575733

By:

Xie, Mingming;
Li, Dan;
Zeng, Haohao;
Huang, Yulin;
Xu, Rui;
Wang, Zhen;
Yu, Jiacheng;
Sun, Yu'e

Publication type:

Article

Intrathecal Injection of JWH-015 Attenuates Bone Cancer Pain Via Time-Dependent Modification of Pro-inflammatory Cytokines Expression and Astrocytes Activity in Spinal Cord.

Published in:

Inflammation, 2015, v. 38, n. 5, p. 1880, doi. 10.1007/s10753-015-0168-3

By:

Lu, Cui'e;
Liu, Yue;
Sun, Bei;
Sun, Yu'e;
Hou, Bailing;
Zhang, Yu;
Ma, Zhengliang;
Gu, Xiaoping

Publication type:

Article

Ion channels in cancer-induced bone pain: from molecular mechanisms to clinical applications.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1239599

By:

Huan-Jun Lu;
Xiao-Bo Wu;
Qian-Qi Wei

Publication type:

Article

Bone Pain in Cancer Patients: Mechanisms and Current Treatment.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 23, p. 6047, doi. 10.3390/ijms20236047

By:

Zajączkowska, Renata;
Kocot-Kępska, Magdalena;
Leppert, Wojciech;
Wordliczek, Jerzy

Publication type:

Article

External application of traditional Chinese medicine in the treatment of bone cancer pain: a meta-analysis.

Published in:

2016

By:

Xiangyong, Yan;
Zhongsheng, Yan;
Wenchao, Liu;
Hui, Ding;
Shuzhou, Qiao;
Gang, Chen;
XiaoHui, Wang;
Lian, Zhang;
Yan, Xiangyong;
Yan, Zhongsheng;
Liu, Wenchao;
Ding, Hui;
Qiao, Shuzhou;
Chen, Gang;
Wang, XiaoHui;
Zhang, Lian

Publication type:

journal article

A systematic review and meta-analysis on the use of traditional Chinese medicine compound kushen injection for bone cancer pain.

Published in:

Supportive Care in Cancer, 2014, v. 22, n. 3, p. 825, doi. 10.1007/s00520-013-2063-5

By:

Yanju, Bao;
Yang, Liping;
Hua, Baojin;
Hou, Wei;
Shi, Zhan;
Li, Weidong;
Li, Conghuang;
Chen, Cihui;
Liu, Rui;
Qin, Yinggang;
Lv, Wenliang

Publication type:

Article