Works matching Biopharmaceutics

Results: 5000

A perspective on the physicochemical and biopharmaceutic properties of marketed antiseizure drugs—From phenobarbital to cenobamate and beyond.

Published in:

Epilepsia (Series 4), 2020, v. 61, n. 8, p. 1543, doi. 10.1111/epi.16597

By:

Odi, Reem;
Bibi, David;
Wager, Travis;
Bialer, Meir

Publication type:

Article

Physiologically Based Biopharmaceutics Model of Apixaban for Biopharmaceutics Risk Assessment.

Published in:

Pharmaceutics, 2025, v. 17, n. 3, p. 382, doi. 10.3390/pharmaceutics17030382

By:

Paixão, Paulo;
Petric, Zvonimir;
Morais, José A. G.

Publication type:

Article

Effect of the Similarity of Formulations and Excipients of Approved Generic Drug Products on In Vivo Bioequivalence for Putative Biopharmaceutics Classification System Class III Drugs.

Published in:

Pharmaceutics, 2023, v. 15, n. 9, p. 2366, doi. 10.3390/pharmaceutics15092366

By:

Ren, Ping;
Chan, Theresa;
Yang, Wen-Cheng;
Frost, Mitchell;
Wang, Yan;
Luke, Markham;
Kim, Myong-Jin;
Lionberger, Robert;
Zhang, Yi

Publication type:

Article

Current State and Challenges of Physiologically Based Biopharmaceutics Modeling (PBBM) in Oral Drug Product Development.

Published in:

Pharmaceutical Research, 2023, v. 40, n. 2, p. 321, doi. 10.1007/s11095-022-03373-0

By:

Wu, Di;
Li, Min

Publication type:

Article

Scipion PKPD: an Open-Source Platform for Biopharmaceutics, Pharmacokinetics and Pharmacodynamics Data Analysis.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 7, p. 1169, doi. 10.1007/s11095-021-03065-1

By:

Sorzano, C. O. S.;
Fonseca-Reyna, Y.;
de la Cruz-Moreno, M. A. Pérez

Publication type:

Article

Study on Biopharmaceutics Classification and Oral Bioavailability of a Novel Multikinase Inhibitor NCE for Cancer Therapy.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 5, p. 7199, doi. 10.3390/ijms15057199

By:

Yang Yang;
Chun-Mei Fan;
Xuan He;
Ke Ren;
Jin-Kun Zhang;
Ying-Ju He;
Luo-Ting Yu;
Ying-Lan Zhao;
Chang-Yang Gong;
Yu Zheng;
Xiang-Rong Song;
Jun Zeng

Publication type:

Article

Gliclazide: Biopharmaceutics Characteristics to Discuss the Biowaiver of Immediate and Extended Release Tablets.

Published in:

Applied Sciences (2076-3417), 2020, v. 10, n. 20, p. 7131, doi. 10.3390/app10207131

By:

Mapa, Bruna de Carvalho;
Araújo, Lorena Ulhôa;
Silva-Barcellos, Neila Márcia;
Caldeira, Tamires Guedes;
Souza, Jacqueline

Publication type:

Article

Biopharmaceutics studies applied to goyazensolide: a drug candidate from Lychnophora species.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 8, p. 1140, doi. 10.1093/jpp/rgac020

By:

Tana, Iara Dévula Tiso;
Saúde-Guimarães, Dênia Antunes;
Caldeira, Tamires Guedes;
Marques, Maria Betânia de Freitas;
Mussel, Wagner da Nova;
Souza, Jacqueline de

Publication type:

Article

Matrix effects of the hydroethanolic extract and the butanol fraction of calyces from Physalis peruviana L. on the biopharmaceutics classification of rutin.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 5, p. 738, doi. 10.1111/jphp.13248

By:

Domínguez Moré, Gina Paola;
Feltrin, Clarissa;
Brambila, Paula Freire;
Cardona, María Isabel;
Echeverry, Sandra Milena;
Simões, Cláudia Maria Oliveira;
Aragón, Diana Marcela

Publication type:

Article

Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models.

Published in:

Journal of Pharmacy & Pharmacology, 2016, v. 68, n. 12, p. 1501, doi. 10.1111/jphp.12618

By:

Hansmann, Simone;
Darwich, Adam;
Margolskee, Alison;
Aarons, Leon;
Dressman, Jennifer

Publication type:

Article

Acceptability and characteristics of 124 human bioequivalence studies with active substances classified according to the Biopharmaceutic Classification System.

Published in:

British Journal of Clinical Pharmacology, 2010, v. 70, n. 5, p. 694, doi. 10.1111/j.1365-2125.2010.03757.x

By:

Ramirez, Elena;
Laosa, Olga;
Guerra, Pedro;
Duque, Blanca;
Mosquera, Beatriz;
Borobia, Alberto M.;
Lei, Suhua H.;
Carcas, Antonio J.;
Frias, Jesus

Publication type:

Article

Surge Dose ® Formulations of NSAIDs Provide for Ultra-Rapid and Consistent Drug Absorption in Both the Fasted and Fed State as Predicted by Physiologically Based Biopharmaceutics Modelling.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 708, doi. 10.3390/pharmaceutics17060708

By:

Dickinson, Harri;
Jiang, Zhixin;
Dickinson, Paul A.;
Wilding, Ian R.;
Elliott, Geraldine A.

Publication type:

Article

Biopharmaceutics Classification by High Throughput Solubility Assay and PAMPA.

Published in:

Drug Development & Industrial Pharmacy, 2004, v. 30, n. 2, p. 181, doi. 10.1081/DDC-120028713

By:

Obata, Kouki;
Sugano, Kiyohiko;
Machida, Minoru;
Aso, Yoshinori

Publication type:

Article

Biopharmaceutics classification and pharmacokinetics study of magnesium orotate.

Published in:

Magnesium Research, 2019, v. 32, n. 4, p. 132, doi. 10.1684/mrh.2020.0462

By:

Verma, Hitesh;
Garg, Rajeev

Publication type:

Article

Predicting Interactions between Rifampin and Antihypertensive Drugs Using the Biopharmaceutics Drug Disposition Classification System.

Published in:

Pharmacotherapy, 2020, v. 40, n. 4, p. 274, doi. 10.1002/phar.2380

By:

Liu, Wei;
Yan, Tingting;
Chen, Ken;
Yang, Li;
Benet, Leslie Z.;
Zhai, Suodi

Publication type:

Article

Physiologically Based Biopharmaceutics Model (PBBM) of Minimally Absorbed Locally Acting Drugs in the Gastrointestinal Tract—Case Study: Tenapanor.

Published in:

Pharmaceutics, 2023, v. 15, n. 12, p. 2726, doi. 10.3390/pharmaceutics15122726

By:

Stamatopoulos, Konstantinos;
Mistry, Nena;
Fotaki, Nikoletta;
Turner, David B.;
Swift, Brandon

Publication type:

Article

Classification of WHO Essential Oral Medicines for Children Applying a Provisional Pediatric Biopharmaceutics Classification System.

Published in:

Pharmaceutics, 2019, v. 11, n. 11, p. 567, doi. 10.3390/pharmaceutics11110567

By:

delMoral-Sanchez, Jose-Manuel;
Gonzalez-Alvarez, Isabel;
Gonzalez-Alvarez, Marta;
Navarro, Andres;
Bermejo, Marival

Publication type:

Article

Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults.

Published in:

Pharmaceutical Research, 2023, v. 40, n. 2, p. 387, doi. 10.1007/s11095-022-03339-2

By:

Pepin, Xavier J. H.;
Hammarberg, Maria;
Mattinson, Alexandra;
Moir, Andrea

Publication type:

Article

Physiologically Based Pharmacokinetics Modeling in Biopharmaceutics: Case Studies for Establishing the Bioequivalence Safe Space for Innovator and Generic Drugs.

Published in:

Pharmaceutical Research, 2023, v. 40, n. 2, p. 337, doi. 10.1007/s11095-022-03319-6

By:

Wu, Di;
Sanghavi, Maitri;
Kollipara, Sivacharan;
Ahmed, Tausif;
Saini, Anuj K;
Heimbach, Tycho

Publication type:

Article

The Use of Physiologically Based Pharmacokinetic Analyses—in Biopharmaceutics Applications -Regulatory and Industry Perspectives.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 8, p. 1681, doi. 10.1007/s11095-022-03280-4

By:

Anand, Om;
Pepin, Xavier J. H.;
Kolhatkar, Vidula;
Seo, Paul

Publication type:

Article

Biopharmaceutics classification and intestinal absorption of chikusetsusaponin IVa.

Published in:

Biopharmaceutics & Drug Disposition, 2019, v. 40, n. 8, p. 276, doi. 10.1002/bdd.2200

By:

Zhang, Wenzhou;
Liu, Hui;
Liu, Chongfeng

Publication type:

Article

COVID-19 Tedavisinde Kullanılan İlaçların Biyofarmasötik, Farmakokinetik ve Patent Değerlendirmeleri: Ülkemizde Eşdeğer İlaçların Geliştirilmesindeki Güncel Durum.

Published in:

Gazi Medical Journal, 2020, v. 31, p. 498, doi. 10.12996/gmj.2020.119

By:

Usta, Duygu Yılmaz;
Teksin, Zeynep Şafak

Publication type:

Article

Risk assessment for extending the Biopharmaceutics Classification System-based biowaiver of immediate release dosage forms of fluconazole in adults to the paediatric population.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 8, p. 1156, doi. 10.1111/jphp.12411

By:

Charoo, Naseem A.;
Cristofoletti, Rodrigo;
Dressman, Jennifer B.

Publication type:

Article

Bioactivities, Biopharmaceutics, and Advanced Drug Delivery Systems of Magnolol.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2024, v. 58, p. S1108, doi. 10.5530/ijper.58.4s.110

By:

Kotta, Sabna;
Eshmawi, Bayan A.;
Alahmadi, Amerh Aiad;
Aldawsari, Hibah Mubarak;
Badr-Eldin, Shaimaa M.;
Nair, Anroop B.

Publication type:

Article

Integrating In Vitro Biopharmaceutics into Physiologically Based Biopharmaceutic Model (PBBM) to Predict Food Effect of BCS IV Zwitterionic Drug (GSK3640254).

Published in:

Pharmaceutics, 2023, v. 15, n. 2, p. 521, doi. 10.3390/pharmaceutics15020521

By:

Stamatopoulos, Konstantinos;
Ferrini, Paola;
Nguyen, Dung;
Zhang, Ying;
Butler, James M.;
Hall, Jon;
Mistry, Nena

Publication type:

Article

The utility of rat jejunal permeability for biopharmaceutics classification system.

Published in:

Drug Development & Industrial Pharmacy, 2009, v. 35, n. 12, p. 1496, doi. 10.3109/03639040903037199

By:

Zakeri-Milani, Parvin;
Valizadeh, Hadi;
Tajerzadeh, Hosnieh;
Islambulchilar, Ziba

Publication type:

Article

Biopharmaceutics 4.0, Advanced Pre-Clinical Development of mRNA-Encoded Monoclonal Antibodies to Immunosuppressed Murine Models.

Published in:

Vaccines, 2021, v. 9, n. 8, p. 890, doi. 10.3390/vaccines9080890

By:

Ouranidis, Andreas;
Choli-Papadopoulou, Theodora;
Papachristou, Eleni T.;
Papi, Rigini;
Kostomitsopoulos, Nikolaos

Publication type:

Article

Physiologically-Based Biopharmaceutics Modeling for Ibuprofen: Identifying Key Formulation Parameter and Virtual Bioequivalence Assessment.

Published in:

Pharmaceutics, 2025, v. 17, n. 4, p. 408, doi. 10.3390/pharmaceutics17040408

By:

Zarzoso-Foj, Javier;
Cuquerella-Gilabert, Marina;
Merino-Sanjuan, Matilde;
Reig-Lopez, Javier;
Mangas-Sanjuán, Víctor;
Garcia-Arieta, Alfredo

Publication type:

Article

In Vivo Predictive Dissolution and Biopharmaceutic-Based In Silico Model to Explain Bioequivalence Results of Valsartan, a Biopharmaceutics Classification System Class IV Drug.

Published in:

Pharmaceutics, 2024, v. 16, n. 3, p. 390, doi. 10.3390/pharmaceutics16030390

By:

Gonzalez-Alvarez, Isabel;
Ruiz-Picazo, Alejandro;
Selles-Talavera, Ruben;
Figueroa-Campos, Andres;
Merino, Virginia;
Bermejo, Marival;
Gonzalez-Alvarez, Marta

Publication type:

Article

Development of Extended-Release Mini-Tablets Containing Metoprolol Supported by Design of Experiments and Physiologically Based Biopharmaceutics Modeling.

Published in:

Pharmaceutics, 2022, v. 14, n. 5, p. 892, doi. 10.3390/pharmaceutics14050892

By:

Issa, Michele Georges;
de Souza, Natalia Vieira;
Jou, Bruna Wenyi Chuang;
Duque, Marcelo Dutra;
Ferraz, Humberto Gomes

Publication type:

Article

A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP.

Published in:

Pharmaceutics, 2020, v. 12, n. 1, p. 74, doi. 10.3390/pharmaceutics12010074

By:

Bermejo, Marival;
Hens, Bart;
Dickens, Joseph;
Mudie, Deanna;
Paixão, Paulo;
Tsume, Yasuhiro;
Shedden, Kerby;
Amidon, Gordon L.

Publication type:

Article

Integration of artificial neural network and physiologically based biopharmaceutic models in the development of sustained‐release formulations.

Published in:

Biopharmaceutics & Drug Disposition, 2023, v. 44, n. 4, p. 335, doi. 10.1002/bdd.2376

By:

Severino Martins, Frederico;
Borges, Luiza;
Oliveira do Couto, Rene;
Schaller, Stephan;
de Freitas, Osvaldo

Publication type:

Article

Drugs are Absorbed in Finite Time: A New Era in Biopharmaceutics and Pharmacokinetics.

Published in:

Acta Pharmaceutica Hungarica, 2021, v. 91, n. 3/4, p. 148, doi. 10.33892/aph.2021.91.148-149

By:

MACHERAS, PANOS

Publication type:

Article

Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 4, p. 437, doi. 10.1093/jpp/rgaa055

By:

O'Dwyer, Patrick J.;
Box, Karl J.;
Dressman, Jennifer;
Griffin, Brendan T.;
Henze, Laura J.;
Litou, Chara;
Pentafragka, Christina;
Statelova, Marina;
Vertzoni, Maria;
Reppas, Christos

Publication type:

Article

Polymorphic characterization and implications on biopharmaceutics properties of potential anti‐inflammatory drug candidate eremantholide C from Lychnophora trichocarpha (Brazilian Arnica).

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 6, p. 910, doi. 10.1111/jphp.13080

By:

Caldeira, Tamires G.;
Saúde‐Guimarães, Dênia A.;
De Lacerda, Dâmaris L. R.;
Mussel, Wagner Da Nova;
Yoshida, Maria Irene;
De Souza, Jacqueline

Publication type:

Article

Adult and pediatric physiologically‐based biopharmaceutics modeling to explain lamotrigine immediate release absorption process.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 2, p. 208, doi. 10.1002/psp4.13071

By:

Caleffi‐Marchesini, Edilainy Rizzieri;
Herling, Amanda Antunes;
Macente, Julia;
Bonan, Rodolfo Hernandes;
de Freitas Lima, Priscila;
Moreno, Rafaela;
Alexandre, Veriano;
Charbe, Nitin Bharat;
Borghi‐Pangoni, Fernanda Belincanta;
Cristofoletti, Rodrigo;
Diniz, Andréa

Publication type:

Article

Application of physiologically based biopharmaceutics modeling to understand the impact of dissolution differences on in vivo performance of immediate release products: The case of bisoprolol.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 6, p. 622, doi. 10.1002/psp4.12634

By:

Macwan, Joyce S.;
Fraczkiewicz, Grace;
Bertolino, Mauro;
Krüger, Phillip;
Peters, Sheila‐Annie

Publication type:

Article

POPULATION-BASED APPROACH TO ANALYZE SPARSE SAMPLING DATA IN BIOPHARMACEUTIC AND PHARMACOKINETIC STUDIES USING NONMEM AND MONOLIX.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2017, v. 28, n. 4, p. 205, doi. 10.14499/indonesianjpharm28iss4pp205

By:

Nugroho, Akhmad Kharis;
Hakim, Arief Rahman;
Hakim, Lukman

Publication type:

Article

Corrigendum to “biopharmaceutics classification and pharmacokinetics study of magnesium orotate” (Mag Res 2019;32:132-42) [1].

Published in:

2022

By:

Verma, Hitesh;
Garg, Rajeev

Publication type:

Correction Notice

Buccal Absorption of Biopharmaceutics Classification System III Drugs: Formulation Approaches and Mechanistic Insights.

Published in:

Pharmaceutics, 2024, v. 16, n. 12, p. 1563, doi. 10.3390/pharmaceutics16121563

By:

Sabra, Rayan;
Kirby, Daniel;
Chouk, Vikram;
Malgorzata, Kleta;
Mohammed, Afzal R.

Publication type:

Article

Physiologically Based Biopharmaceutics Modeling of Food Effect for Basmisanil: A Retrospective Case Study of the Utility for Formulation Bridging.

Published in:

Pharmaceutics, 2023, v. 15, n. 1, p. 191, doi. 10.3390/pharmaceutics15010191

By:

Belubbi, Tejashree;
Bassani, Davide;
Stillhart, Cordula;
Parrott, Neil

Publication type:

Article

ICH Guideline for Biopharmaceutics Classification System-Based Biowaiver (M9): Toward Harmonization in Latin American Countries.

Published in:

Pharmaceutics, 2021, v. 13, n. 3, p. 363, doi. 10.3390/pharmaceutics13030363

By:

Miranda, Claudia;
Aceituno, Alexis;
Fernández, Mirna;
Mendes, Gustavo;
Rodríguez, Yanina;
Llauró, Verónica;
Cabrera-Pérez, Miguel Ángel;
Conway, Barbara R.

Publication type:

Article

Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations.

Published in:

Pharmaceutics, 2020, v. 12, n. 3, p. 269, doi. 10.3390/pharmaceutics12030269

By:

Varela-Fernández, Rubén;
Díaz-Tomé, Victoria;
Luaces-Rodríguez, Andrea;
Conde-Penedo, Andrea;
García-Otero, Xurxo;
Luzardo-Álvarez, Asteria;
Fernández-Ferreiro, Anxo;
Otero-Espinar, Francisco J.

Publication type:

Article

SubQ-Sim: A Subcutaneous Physiologically Based Biopharmaceutics Model. Part 1: The Injection and System Parameters.

Published in:

Pharmaceutical Research, 2023, v. 40, n. 9, p. 2195, doi. 10.1007/s11095-023-03567-0

By:

Pepin, Xavier J. H.;
Grant, Iain;
Wood, J. Matthew

Publication type:

Article

Possibility of extending biopharmaceutics classification system based biowaiver to BCS class IIa drug.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2019, v. 32, n. 5, p. 2065

By:

Khalid, Farah;
Hassan, Syed Muhammad Farid;
Noor, Rabia;
Zaheer, Kamran;
Hassan, Fouzia;
Muhammad, Iyad Naeem

Publication type:

Article

Justification of widened dissolution specifications of an extended-release product using physiologically based biopharmaceutics modeling.

Published in:

Xenobiotica, 2024, v. 54, n. 10, p. 781, doi. 10.1080/00498254.2024.2411980

By:

Bhattiprolu, Adithya Karthik;
Kollipara, Sivacharan;
Boddu, Rajkumar;
Ahmed, Tausif

Publication type:

Article

Biopharmaceutics Classification System.

Published in:

Systematic Reviews in Pharmacy, 2010, v. 1, n. 1, p. 62, doi. 10.4103/0975-8453.59513

By:

Shidhaye, S. S.;
Lotlikar, V. M.;
Ghule, A. M.;
Phutane, P. K.;
Kadam, V. J.

Publication type:

Article

Physicochemical Properties of Lomefloxacin, Levofloxacin, and Moxifloxacin Relevant to the Biopharmaceutics Classification System.

Published in:

Acta Chimica Slovenica, 2014, v. 61, n. 4, p. 827

By:

Kłosińska-Szmurło, Ewa;
Grudzień, Monika;
Betlejewska-Kielak, Katarzyna;
Pluciński, Franciszek;
Biernacka, Joanna;
Mazurek, Aleksander Paweł

Publication type:

Article

Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.

Published in:

British Journal of Clinical Pharmacology, 2016, v. 81, n. 1, p. 137, doi. 10.1111/bcp.12752

By:

Somani, Amit A.;
Thelen, Kirstin;
Zheng, Songmao;
Trame, Mirjam N.;
Coboeken, Katrin;
Meyer, Michaela;
Schnizler, Katrin;
Ince, Ibrahim;
Willmann, Stefan;
Schmidt, Stephan

Publication type:

Article

Elucidating the Role of Dose in the Biopharmaceutics Classification of Drugs: The Concepts of Critical Dose, Effective In Vivo Solubility, and Dose-Dependent BCS.

Published in:

Pharmaceutical Research, 2012, v. 29, n. 11, p. 3188, doi. 10.1007/s11095-012-0815-4

By:

Charkoftaki, Georgia;
Dokoumetzidis, Aristides;
Valsami, Georgia;
Macheras, Panos

Publication type:

Article