Works matching Antisense nucleic acids

Results: 710

Antisense and Functional Nucleic Acids in Rational Drug Development.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 3, p. 221, doi. 10.3390/antibiotics13030221

By:

Penchovsky, Robert;
Georgieva, Antoniya V.;
Dyakova, Vanya;
Traykovska, Martina;
Pavlova, Nikolet

Publication type:

Article

RNA Secondary Structure-Based Design of Antisense Peptide Nucleic Acids for Modulating Disease-Associated Aberrant Tau Pre-mRNA Alternative Splicing.

Published in:

Molecules, 2019, v. 24, n. 16, p. 3020, doi. 10.3390/molecules24163020

By:

Ong, Alan Ann Lerk;
Tan, Jiazi;
Bhadra, Malini;
Dezanet, Clément;
Patil, Kiran M.;
Chong, Mei Sian;
Kierzek, Ryszard;
Decout, Jean-Luc;
Roca, Xavier;
Chen, Gang;
Yavin, Eylon

Publication type:

Article

Down-Modulation of Survivin Expression and Inhibition of Tumor Growth In Vivo by EZN-3042, A Locked Nucleic Acid Antisense Oligonucleotide.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2010, v. 29, n. 2, p. 97, doi. 10.1080/15257771003597733

By:

Sapra, Puja;
Wang, Maoliang;
Bandaru, Raj;
Zhao, Hong;
Greenberger, LeeM.;
Horak, IvanD.

Publication type:

Article

Pyrenebutyrate Enhances the Antibacterial Effect of Peptide-Coupled Antisense Peptide Nucleic Acids in Streptococcus pyogenes.

Published in:

Microorganisms, 2023, v. 11, n. 9, p. 2131, doi. 10.3390/microorganisms11092131

By:

Abt, Corina;
Gerlach, Lisa Marie;
Bull, Jana;
Jacob, Anette;
Kreikemeyer, Bernd;
Patenge, Nadja

Publication type:

Article

Construction of Graphene Oxide Probes Loaded with Antisense Peptide Nucleic Acid and Doxorubicin for Regulating Telomerase Activity and Inducing Apoptosis of Cancer Cells.

Published in:

Biosensors (2079-6374), 2025, v. 15, n. 6, p. 337, doi. 10.3390/bios15060337

By:

Zhu, Yanyan;
Ji, Qinghong;
Hong, Min

Publication type:

Article

The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187286

By:

Uemura, Yasunori;
Hagiwara, Kenji;
Kobayashi, Katsuya

Publication type:

Article

Subtractive modification of bacterial consortium using antisense peptide nucleic acids.

Published in:

Frontiers in Microbiology, 2024, p. 1, doi. 10.3389/fmicb.2023.1321428

By:

Tatsuya Hizume;
Yu Sato;
Hiroaki Iwaki;
Kohsuke Honda;
Kenji Okano

Publication type:

Article

Inhibition of biofilm formation by the antisense peptide nucleic acids targeted at the motA gene in Pseudomonas aeruginosa PAO1 strain.

Published in:

World Journal of Microbiology & Biotechnology, 2011, v. 27, n. 9, p. 1981, doi. 10.1007/s11274-011-0658-x

By:

Jian'e Hu;
Yun Xia;
Ying Xiong;
Xiaofeng Li;
Xiaoyan Su

Publication type:

Article

Development of antisense peptide-peptide nucleic acids against fluoroquinolone-resistant Escherichia coli.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 8, p. 2052, doi. 10.1093/jac/dkad203

By:

Kim, Se Kye;
Lee, Jun Bong;
Lee, Hyung Tae;
Han, Dalmuri;
Yoon, Jang Won

Publication type:

Article

Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection.

Published in:

Gene Therapy, 2011, v. 18, n. 4, p. 326, doi. 10.1038/gt.2010.133

By:

Zhang, Y;
Qu, Z;
Kim, S;
Shi, V;
Liao, B;
Kraft, P;
Bandaru, R;
Wu, Y;
Greenberger, L M;
Horak, I D

Publication type:

Article

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010682

By:

Gupta, Nidhi;
Fisker, Niels;
Asselin, Marie-Claude;
Lindholm, Marie;
Rosenbohm, Christoph;
Ørum, Henrik;
Elmén, Joacim;
Seidah, Nabil G.;
Straarup, Ellen Marie

Publication type:

Article

Targeting murine alveolar macrophages by the intratracheal administration of locked nucleic acid containing antisense oligonucleotides.

Published in:

Drug Delivery, 2019, v. 26, n. 1, p. 803, doi. 10.1080/10717544.2019.1648589

By:

Uemura, Yasunori;
Kobayashi, Katsuya

Publication type:

Article

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128686

By:

Mutso, Margit;
Nikonov, Andrei;
Pihlak, Arno;
Žusinaite, Eva;
Viru, Liane;
Selyutina, Anastasia;
Reintamm, Tõnu;
Kelve, Merike;
Saarma, Mart;
Karelson, Mati;
Merits, Andres

Publication type:

Article

Antisense peptide nucleic acid-mediated knockdown of the p75 neurotrophin receptor delays motor neuron disease in mutant SOD1 transgenic mice.

Published in:

Journal of Neurochemistry, 2003, v. 87, n. 3, p. 752, doi. 10.1046/j.1471-4159.2003.02053.x

By:

Turmer, Bradley J.;
Cheah, Irwin K.;
Macfarlane, Katherine J.;
Lopes, Elizabeth C.;
Petratos, Steven;
Langford, Steven J.;
Cheema, Surindar S.

Publication type:

Article

2'-O-Methyl RNA/Ethylene-Bridged Nucleic Acid Chimera Antisense Oligonucleotides to Induce Dystrophin Exon 45 Skipping.

Published in:

Genes, 2017, v. 8, n. 2, p. 67, doi. 10.3390/genes8020067

By:

Tomoko Lee;
Hiroyuki Awano;
Mariko Yagi;
Masaaki Matsumoto;
Nobuaki Watanabe;
Ryoya Goda;
Makoto Koizumi;
Yasuhiro Takeshima;
Masafumi Matsuo

Publication type:

Article

IMPLICATIONS OF SENSE/ANTISENSE NUCLEIC-ACID CODONS ON AMINO-ACID COUNTS.

Published in:

Studia Universitatis Babes-Bolyai, Chemia, 2010, n. 4, p. 167

By:

Rosenfeld, Vladimir R.;
Klein, Douglas J.

Publication type:

Article

Cooperative Cellular Uptake and Activity of Octaarginine Antisense Peptide Nucleic Acid (PNA) Conjugates.

Published in:

Biomolecules (2218-273X), 2019, v. 9, n. 10, p. 554, doi. 10.3390/biom9100554

By:

Ghavami, Mahdi;
Shiraishi, Takehiko;
Nielsen, Peter E.

Publication type:

Article

Cell-permeable peptide nucleic acid antisense oligonucleotide platform targeting human betacoronaviruses.

Published in:

Frontiers in Microbiology, 2023, p. 1, doi. 10.3389/fmicb.2023.1258091

By:

Soree Park;
Seong Ho Kim;
Dezhbord, Mehrangiz;
Eun-Hwi Lee;
Yeasel Jeon;
Daram Jung;
Se Hun Gu;
Chiho Yu;
Seung Ho Lee;
Sung Chun Kim;
Kyun-Hwan Kim

Publication type:

Article

De Novo Potent Peptide Nucleic Acid Antisense Oligomer Inhibitors Targeting SARS-CoV-2 RNA-Dependent RNA Polymerase via Structure-Guided Drug Design.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17473, doi. 10.3390/ijms242417473

By:

Shehzadi, Kiran;
Yu, Mingjia;
Liang, Jianhua

Publication type:

Article

Topical Application of Peptide Nucleic Acid Antisense Oligonucleotide for MMP-1 and Its Potential Anti-Aging Properties.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 7, p. 2472, doi. 10.3390/jcm12072472

By:

Lee, Young In;
Lee, Sang Gyu;
Jung, Inhee;
Suk, Jangmi;
Baeg, Chaemin;
Han, Seon-Young;
Seo, Jeong Yeon;
Jung, Daram;
Jeon, Yeasel;
Lee, Ju Hee

Publication type:

Article

Vegf or EphA2 Antisense Polyamide-nucleic acids; Vascular Localization and Suppression of Retinal Neovascularization.

Published in:

Molecular Therapy, 2007, v. 15, n. 11, p. 1924, doi. 10.1038/sj.mt.6300276

By:

Jikui Shen;
Bing Xie;
Hatara, Christina M.;
Hackett, Sean F.;
Campochiaro, Peter A.

Publication type:

Article

First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer.

Published in:

British Journal of Cancer, 2013, v. 109, n. 10, p. 2579, doi. 10.1038/bjc.2013.619

By:

Bianchini, D;
Omlin, A;
Pezaro, C;
Lorente, D;
Ferraldeschi, R;
Mukherji, D;
Crespo, M;
Figueiredo, I;
Miranda, S;
Riisnaes, R;
Zivi, A;
Buchbinder, A;
Rathkopf, D E;
Attard, G;
Scher, H I;
de Bono, J;
Danila, D C

Publication type:

Article

An antisense amido-bridged nucleic acid gapmer oligonucleotide targeting SRRM4 alters REST splicing and exhibits anti-tumor effects in small cell lung cancer and prostate cancer cells.

Published in:

Cancer Cell International, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12935-022-02842-1

By:

Yoshida, Misa;
Oda, Chihiro;
Mishima, Keishiro;
Tsuji, Itsuki;
Obika, Satoshi;
Shimojo, Masahito

Publication type:

Article

Survivin反义核酸联合紫杉醇对皮下荷瘤Balb/c小鼠模型的治疗作用.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2015, v. 36, n. 4, p. 467, doi. 10.7652/jdyxb201504008

By:

吴丽贤;
黄立森;
陈瑞家;
田崛;
柯方

Publication type:

Article

RNA Silencing in the Struggle against Disease.

Published in:

Annals of the New York Academy of Sciences, 2006, v. 1082, n. 1, p. 44, doi. 10.1196/annals.1348.051

By:

PATZEL, VOLKER;
DIETRICH, ISABELL;
KAUFMANN, STEFAN H.E.

Publication type:

Article

Selected strategies to fight pathogenic bacteria.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2022.2155816

By:

Plotniece, Aiva;
Sobolev, Arkadij;
Supuran, Claudiu T.;
Carta, Fabrizio;
Björkling, Fredrik;
Franzyk, Henrik;
Yli-Kauhaluoma, Jari;
Augustyns, Koen;
Cos, Paul;
De Vooght, Linda;
Govaerts, Matthias;
Aizawa, Juliana;
Tammela, Päivi;
Žalubovskis, Raivis

Publication type:

Article

Cover Picture: Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications (Chem. Rec. 4/2022).

Published in:

Chemical Record, 2022, v. 22, n. 4, p. 1, doi. 10.1002/tcr.202280401

By:

Fàbrega, Carme;
Aviñó, Anna;
Eritja, Ramon

Publication type:

Article

An intranasal ASO therapeutic targeting SARS-CoV-2.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32216-0

By:

Zhu, Chi;
Lee, Justin Y.;
Woo, Jia Z.;
Xu, Lei;
Nguyenla, Xammy;
Yamashiro, Livia H.;
Ji, Fei;
Biering, Scott B.;
Van Dis, Erik;
Gonzalez, Federico;
Fox, Douglas;
Wehri, Eddie;
Rustagi, Arjun;
Pinsky, Benjamin A.;
Schaletzky, Julia;
Blish, Catherine A.;
Chiu, Charles;
Harris, Eva;
Sadreyev, Ruslan I.;
Stanley, Sarah

Publication type:

Article

Antisense therapeutics.

Published in:

Nature Biotechnology, 1999, v. 17, n. 4, p. 403, doi. 10.1038/7973

By:

Persidis, Aris

Publication type:

Article

Synthesis and applications of bicyclic sugar modified locked nucleic acids: A review.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2022, v. 41, n. 5/6, p. 503, doi. 10.1080/15257770.2022.2052316

By:

Goswami, Arkaja;
Prasad, Ashok K.;
Maity, Jyotirmoy;
Khaneja, Neerja

Publication type:

Article

Phase-I trial of survivin inhibition with EZN-3042 in dogs with spontaneous lymphoma.

Published in:

BMC Veterinary Research, 2020, v. 16, n. 1, p. 1, doi. 10.1186/s12917-020-02317-3

By:

Thamm, Douglas H.;
Joseph, Jenette K.;
Rose, Barbara J.;
Meuten, Travis K.;
Weishaar, Kristen M.

Publication type:

Article

Antimicrobial activity of antisense peptide-peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms.

Published in:

2017

By:

Otsuka, Taketo;
Brauer, Aimee L;
Kirkham, Charmaine;
Sully, Erin K;
Pettigrew, Melinda M;
Kong, Yong;
Geller, Bruce L;
Murphy, Timothy F

Publication type:

journal article

Target optimization for peptide nucleic acid (PNA)-mediated antisense inhibition of the CmeABC multidrug efflux pump in Campylobacter jejuni.

Published in:

2014

By:

Oh, Euna;
Zhang, Qijing;
Jeon, Byeonghwa

Publication type:

journal article

Target optimization for peptide nucleic acid (PNA)-mediated antisense inhibition of the CmeABC multidrug efflux pump in Campylobacter jejuni.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2014, v. 69, n. 2, p. 375

By:

Oh, Euna;
Zhang, Qijing;
Jeon, Byeonghwa

Publication type:

Article

Microarrays for basic studies of nucleic acid hybridization and selection of antisense reagents.

Published in:

1999

By:

Southern, Edwin

Publication type:

Abstract

Potentiating antibiotic efficacy via perturbation of non-essential gene expression.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02783-x

By:

Otoupal, Peter B.;
Eller, Kristen A.;
Erickson, Keesha E.;
Campos, Jocelyn;
Aunins, Thomas R.;
Chatterjee, Anushree

Publication type:

Article

Novel antiviral approaches for Marburg: a promising therapeutics in the pipeline.

Published in:

Frontiers in Microbiology, 2024, p. 1, doi. 10.3389/fmicb.2024.1387628

By:

Srivastava, Shriyansh;
Kumar, Sachin;
Ashique, Sumel;
Sridhar, Sathvik Belagodu;
Shareef, Javedh;
Thomas, Sabin

Publication type:

Article

Exploration of Using Antisense Peptide Nucleic Acid (PNA)-cell Penetrating Peptide (CPP) as a Novel Bactericide against Fire Blight Pathogen Erwinia amylovora.

Published in:

Frontiers in Microbiology, 2017, p. 1, doi. 10.3389/fmicb.2017.00687

By:

Patel, Ravi R.;
Sundin, George W.;
Ching-Hong Yang;
Jie Wang;
Huntley, Regan B.;
Xiaochen Yuan;
Quan Zeng

Publication type:

Article

Effects of antisense oligodeoxynucleotide to type I collagen gene on hypertrophic scars in the transplanted nude mouse model.

Published in:

Journal of Cutaneous Pathology, 2009, v. 36, n. 11, p. 1146, doi. 10.1111/j.1600-0560.2009.01246.x

By:

Xie, Julin;
Qi, Shaohai;
Yuan, Jishan;
Xu, Yinbing;
Li, Tianzeng;
Li, Houdong;
Liu, Xusheng;
Shu, Bin;
Liang, Huizeng

Publication type:

Article

Inhibition of gene expression and growth of multidrug-resistant Acinetobacter baumannii by antisense peptide nucleic acids.

Published in:

Molecular Biology Reports, 2014, v. 41, n. 11, p. 7535, doi. 10.1007/s11033-014-3643-2

By:

Wang, Huijuan;
He, Yunyan;
Xia, Yun;
Wang, Lipeng;
Liang, Shumei

Publication type:

Article

Marriage of convenience.

Published in:

Nature, 1993, v. 365, n. 6446, p. 490, doi. 10.1038/365490a0

By:

Patel, Dinshaw J.

Publication type:

Article

Artificial Activation of Escherichia coli mazEF and hipBA Toxin–Antitoxin Systems by Antisense Peptide Nucleic Acids as an Antibacterial Strategy.

Published in:

Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.02870

By:

Równicki, Marcin;
Pieńko, Tomasz;
Czarnecki, Jakub;
Kolanowska, Monika;
Bartosik, Dariusz;
Trylska, Joanna

Publication type:

Article

Antisense Oligonucleotides in Cancer: Recent Advances.

Published in:

BioDrugs, 2000, v. 13, n. 3, p. 195, doi. 10.2165/00063030-200013030-00005

By:

Lebedeva, I.V.;
Stein, C.A.

Publication type:

Article

Preclinical development of a miR-132 inhibitor for heart failure treatment.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14349-2

By:

Foinquinos, Ariana;
Batkai, Sandor;
Genschel, Celina;
Viereck, Janika;
Rump, Steffen;
Gyöngyösi, Mariann;
Traxler, Denise;
Riesenhuber, Martin;
Spannbauer, Andreas;
Lukovic, Dominika;
Weber, Natalie;
Zlabinger, Katrin;
Hašimbegović, Ena;
Winkler, Johannes;
Fiedler, Jan;
Dangwal, Seema;
Fischer, Martin;
Roche, Jeanne de la;
Wojciechowski, Daniel;
Kraft, Theresia

Publication type:

Article

Antisense Oligonucleotide Reverses Leukodystrophy in Canavan Disease Mice.

Published in:

2020

By:

Hull, Vanessa;
Wang, Yan;
Burns, Travis;
Zhang, Sheng;
Sternbach, Sarah;
McDonough, Jennifer;
Guo, Fuzheng;
Pleasure, David

Publication type:

journal article

Antibiofilm Effects of Novel Compounds in Otitis Media Treatment: Systematic Review.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 23, p. 12841, doi. 10.3390/ijms252312841

By:

Jotic, Ana;
Savic Vujovic, Katarina;
Cirkovic, Andja;
Božić, Dragana D.;
Brkic, Snezana;
Subotic, Nikola;
Bukurov, Bojana;
Korugic, Aleksa;
Cirkovic, Ivana

Publication type:

Article

Boron Clusters as Enhancers of RNase H Activity in the Smart Strategy of Gene Silencing by Antisense Oligonucleotides.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12190, doi. 10.3390/ijms232012190

By:

Kaniowski, Damian;
Kulik, Katarzyna;
Suwara, Justyna;
Ebenryter-Olbińska, Katarzyna;
Nawrot, Barbara

Publication type:

Article

The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9165, doi. 10.3390/ijms22179165

By:

Roig-Carles, David;
Jackson, Holly;
Loveson, Katie F.;
Mackay, Alan;
Mather, Rebecca L.;
Waters, Ella;
Manzo, Massimiliano;
Alborelli, Ilaria;
Golding, Jon;
Jones, Chris;
Fillmore, Helen L.;
Crea, Francesco

Publication type:

Article

Antisense inhibition of the Escherichia coli NrdAB aerobic ribonucleotide reductase is bactericidal due to induction of DNA strand breaks.

Published in:

2021

By:

Campion, Christopher;
Charbon, Godefroid;
Thomsen, Thomas T;
Nielsen, Peter E;
Løbner-Olesen, Anders

Publication type:

journal article

Clinical Trials of Functional Nucleic Acids: Antisense Oligonucleotides and Aptamers.

Published in:

International Journal of Biomedical & Clinical Engineering, 2018, v. 7, n. 2, p. 46, doi. 10.4018/IJBCE.2018070104

By:

Traykovska, Martina;
Miedema, Sjoerd;
Penchovsky, Robert

Publication type:

Article