Works matching Alkylating agents

Results: 4423

Les alkylants.

Published in:

Oncologie (Tech Science Press), 2007, v. 9, n. 11, p. 751, doi. 10.1007/s10269-007-0785-z

By:

Ben Abid, F.;
Gazzah, A.;
Ousbane, A.;
Gutierrez, M.;
Brain, E.

Publication type:

Article

In Vivo Evidence of Melatonin's Protective Role in Alkylating-Agent-Induced Pulmonary Toxicity: A Systematic Review.

Published in:

Antioxidants, 2025, v. 14, n. 6, p. 712, doi. 10.3390/antiox14060712

By:

Sola, Emma;
Morales-García, Jose A.;
López-Muñoz, Francisco;
Ramos, Eva;
Romero, Alejandro

Publication type:

Article

Comparative safety analysis of bevacizumab and alkylating agent in glioblastoma management – What have we learned recently?

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1595642

By:

Qu, Zhizhao;
Zhao, Jiajia;
Yang, Liu;
Fu, Yuanwei;
Bai, Rui;
Li, Jinchuan;
Wang, Hongqin

Publication type:

Article

Alkylating agents in membranous nephropathy: efficacy proven beyond doubt.

Published in:

2010

By:

Hofstra, Julia M.;
Wetzels, Jack F.M.

Publication type:

Editorial

Temozolomide and Other Alkylating Agents in Glioblastoma Therapy.

Published in:

Biomedicines, 2019, v. 7, n. 3, p. 69, doi. 10.3390/biomedicines7030069

By:

Strobel, Hannah;
Baisch, Tim;
Fitzel, Rahel;
Schilberg, Katharina;
Siegelin, Markus D.;
Karpel-Massler, Georg;
Debatin, Klaus-Michael;
Westhoff, Mike-Andrew

Publication type:

Article

Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism C. elegans.

Published in:

Cells (2073-4409), 2023, v. 12, n. 23, p. 2728, doi. 10.3390/cells12232728

By:

Ruszkiewicz, Joanna;
Endig, Lisa;
Güver, Ebru;
Bürkle, Alexander;
Mangerich, Aswin

Publication type:

Article

Alkylating agents are possible inducers of glioblastoma and other brain tumors.

Published in:

Human & Experimental Toxicology, 2024, v. 43, p. 1, doi. 10.1177/09603271241256598

By:

Smith, Carr J.;
Perfetti, Thomas A.;
Chokshi, Chirayu;
Venugopal, Chitra;
Ashford, J. Wesson;
Singh, Sheila K.

Publication type:

Article

Docking analysis of aryl derivatives of diepoxide alkylating agents.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2020, v. 33, n. 5, p. 2017, doi. 10.36721/PJPS.2020.33.5.REG.2017-2021.1

By:

Sheikh, Hamdullah Khadim;
Arshad, Tanzila;
Merajoddin, Maria;
Mohammad, Zainab Sher;
Usman, Rafia;
Hasan, Muhammad Mohtasheemul

Publication type:

Article

Dosage time affects alkylating agents induced micronuclei in mouse peripheral blood reticulocytes through the function of erythropoietin.

Published in:

Journal of Toxicological Sciences, 2019, v. 44, n. 4, p. 273, doi. 10.2131/jts.44.273

By:

Keiichi Itoh;
Shoji Masumori;
Daisuke Mukai;
Hiroyuki Sakakibara;
Michiko Yasuda;
Kayoko Shimoi

Publication type:

Article

A sensitive method for simultaneous screening exposure to 14 alkylating agents based on tripeptide adducts: an efficient approach for chemical weapon verification and chemical impurity profiling in plasma samples.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 15, p. 3353, doi. 10.1007/s00216-025-05870-8

By:

Chen, Bo;
Liang, Deshen;
Yu, Huilan;
Liu, Changcai;
Yuan, Ling;
Wang, Fengyun;
Liu, Shilei

Publication type:

Article

In vitro testing of drug combinations employing nilotinib and alkylating agents with regard to pretransplant conditioning treatment of advanced-phase chronic myeloid leukemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 427, doi. 10.1007/s00280-014-2533-6

By:

Radujkovic, Aleksandar;
Luft, Thomas;
Dreger, Peter;
Ho, Anthony;
Jens Zeller, W.;
Fruehauf, Stefan;
Topaly, Julian

Publication type:

Article

Multi-Omics Analysis of NCI-60 Cell Line Data Reveals Novel Metabolic Processes Linked with Resistance to Alkylating Anti-Cancer Agents.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13242, doi. 10.3390/ijms241713242

By:

Rushing, Blake R.

Publication type:

Article

PQQ Dietary Supplementation Prevents Alkylating Agent-Induced Ovarian Dysfunction in Mice.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.781404

By:

Dai, Xiuliang;
Yi, Xiangjiao;
Wang, Yufeng;
Xia, Wei;
Tao, Jianguo;
Wu, Jun;
Miao, Dengshun;
Chen, Li

Publication type:

Article

Potentiation of alkylating agents by NLCQ-1 or TPZ in vitro and in vivo.

Published in:

Journal of Experimental Therapeutics & Oncology, 2008, v. 7, n. 1, p. 261

By:

Papadopoulou, Maria V.;
Ji, Xinhai;
Bloomer, William D.

Publication type:

Article

Potentiation of alkylating agents by NLCQ-1 or TPZ in vitro and in vivo.

Published in:

Journal of Experimental Therapeutics & Oncology, 2006, v. 5, n. 4, p. 261

By:

Papadopoulou, Maria V.;
Xinhai Ji;
Bloomer, William D.

Publication type:

Article

Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer.

Published in:

Frontiers in Oncology, 2022, v. 11, p. 1, doi. 10.3389/fonc.2021.811635

By:

Chang, Yu-Chan;
Chang, Peter Mu-Hsin;
Li, Chien-Hsiu;
Chan, Ming-Hsien;
Lee, Yi-Jang;
Chen, Ming-Huang;
Hsiao, Michael

Publication type:

Article

Alkylating Agent-Induced High Tumor Mutational Burden in Medullary Thyroid Cancer and Response to Immune Checkpoint Inhibitors: Two Case Reports.

Published in:

Thyroid, 2023, v. 33, n. 11, p. 1368, doi. 10.1089/thy.2023.0144

By:

Moog, Sophie;
Lamartina, Livia;
Bani, Mohamed-Amine;
Al Ghuzlan, Abir;
Friboulet, Luc;
Italiano, Antoine;
Lacroix, Ludovic;
Postel Vinay, Sophie;
Tselikas, Lambros;
Deschamps, Frédéric;
Bonnet, Baptiste;
Pani, Fabiana;
Baudin, Eric;
Hadoux, Julien

Publication type:

Article

Mechanism of Action and Use of Radiomimetic Compounds: Part 1 - Alkylating Agents and Antimetabolites.

Published in:

Military Engineer / Hadmérnök, 2022, v. 17, n. 1, p. 101, doi. 10.32567/hm.2022.1.7

By:

Deli, Gábor

Publication type:

Article

Combination Therapy with Immune Checkpoint Inhibitors and Histone Deacetylase Inhibitors or Alkylating Agents.

Published in:

Cancer Management & Research, 2024, v. 16, p. 855, doi. 10.2147/CMAR.S464245

By:

Joerger, Markus;
Koster, Kira-Lee;
Janik, Tomas;
de Jong, Floris A

Publication type:

Article

Effect of Previous Alkylating Agent Exposure on Follicle Numbers in Cryopreserved Prepubertal and Young Adult Ovarian Tissue after Long-Term Xenografting.

Published in:

Cancers, 2022, v. 14, n. 2, p. 399, doi. 10.3390/cancers14020399

By:

Nurmio, Mirja;
Asadi-Azarbaijani, Babak;
Hou, Mi;
Kiviö, Ronja;
Toppari, Jorma;
Tinkanen, Helena;
Laine, Tiina;
Oskam, Irma C.;
Jahnukainen, Kirsi

Publication type:

Article

Increased frequency of dicentric chromosomes in therapy-related MDS and AML compared to de novo disease is significantly related to previous treatment with alkylating agents and suggests a specific susceptibility to chromosome breakage at the centromere.

Published in:

Leukemia (08876924), 2000, v. 14, n. 1, p. 105, doi. 10.1038/sj.leu.2401594

By:

Anderson, M.K.;
Pedersen-Bjergaard, J.

Publication type:

Article

Primary gonadal failure in children with intracranial brain tumors treated with high dose alkylating agents and radiation sparing therapy: an institutional case series.

Published in:

Pediatric Hematology & Oncology, 2025, v. 42, n. 3, p. 178, doi. 10.1080/08880018.2025.2480741

By:

Cheng, Sylvia;
Riedlinger, Sarah;
Ronsley, Rebecca;
Stewart, Laura;
Hukin, Juliette;
Lam, Carol K.L.

Publication type:

Article

Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients.

Published in:

Xenobiotica, 2017, v. 47, n. 5, p. 394, doi. 10.1080/00498254.2016.1201703

By:

Nassar, Ala F.;
Wisnewski, Adam V.;
King, Ivan

Publication type:

Article

Supported Nickel Nanoparticles as Catalyst in Direct sp3 C−H Alkylation of 9H‐Fluorene Using Alcohols as Alkylating Agent.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 1, p. 1, doi. 10.1002/asia.202400989

By:

M, Vageesh;
Joshi, Harsh;
A S, Anupriya;
Dey, Raju

Publication type:

Article

Chemotherapy with Alkylating Agents and Dental Anomalies in Children: A Systematic Review.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 3, p. 1030, doi. 10.3390/jcm14031030

By:

Gallenzi, Patrizia;
Malatesta, Angela;
Staderini, Edoardo;
Guglielmi, Federica

Publication type:

Article

Temozolomide in Glioblastoma Therapy: Role of Apoptosis, Senescence and Autophagy. Comment on Strobel et al., Temozolomide and Other Alkylating Agents in Glioblastoma Therapy. Biomedicines 2019, 7, 69.

Published in:

2019

By:

Kaina, Bernd

Publication type:

Letter

Efficacy and toxicity of the combination chemotherapy of thalidomide, alkylating agent, and steroid for relapsed/refractory myeloma patients: a report from the Korean Multiple Myeloma Working Party (KMMWP) retrospective study.

Published in:

Cancer Medicine, 2017, v. 6, n. 1, p. 100, doi. 10.1002/cam4.970

By:

Kwon, Jihyun;
Min, Chang‐Ki;
Kim, Kihyun;
Han, Jae‐joon;
Moon, Joon Ho;
Kang, Hye Jin;
Eom, Hyeon‐Seok;
Kim, Min Kyoung;
Kim, Hyo Jung;
Yoon, Dok Hyun;
Lee, Jeong‐Ok;
Lee, Won Sik;
Lee, Jae Hoon;
Lee, Je‐Jung;
Choi, Yoon‐seok;
Kim, Sung hyun;
Yoon, Sung‐soo

Publication type:

Article

Epitaxial Growth of a Thin Layer of Putative Cancer Cells under Limited Resources and in the Presence of an Alkylating Agent.

Published in:

Nonlinear Dynamics, Psychology & Life Sciences, 2022, v. 26, n. 2, p. 131

By:

Aiello, Gaetano L.;
Richards, Kyle A.

Publication type:

Article

Structure-activity study of the interaction of bioreductive benzoquinone alkylating agents with DNA topoisomerase II.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 2, p. 221, doi. 10.1007/s00280-005-0040-5

By:

Hasinoff, Brian B.;
Xing Wu;
Begleiter, Asher;
Guziec, Lynn J.;
Guziec Jr., Frank;
Giorgianni, Angela;
Shaohua Yang;
Yu Jiang;
Yalowich, Jack C.

Publication type:

Article

Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.

Published in:

Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 3, p. 191, doi. 10.1007/s00280-003-0718-5

By:

Fourie, Jeanne;
Guziec, Frank;
Guziec, Lynn;
Monterrosa, Cielo;
Fiterman, Derek J.;
Begleiter, Asher

Publication type:

Article

Novel MGMT inhibitors increase the sensitivity of glioma MGMT-positive cells to treatment with alkylating agents in vitro.

Published in:

Biopolymers & Cell, 2024, v. 40, n. 1, p. 47, doi. 10.7124/bc.000AAD

By:

Zhuvaka, K. S.;
Piven, O. О.;
Macewicz, L. L.;
Ruban, T. P.;
Volynets, G. P.;
Yarmoluk, S. M.;
Dobrzyn, P.;
Lukash, L. L.

Publication type:

Article

Antigenotoxic Effects of Citrus aurenfium L. Fruit Peel Oil on Mutagenicity of Two Alkylating Agents and Two Metals in the Drosophila Wing Spot Test.

Published in:

Environmental & Molecular Mutagenesis, 2009, v. 50, n. 6, p. 483, doi. 10.1002/em.20484

By:

Demir, Eşref;
Kocaoğlu, Serap;
Cetin, Huseyin;
Kaya, Bülent

Publication type:

Article

Kinetks of γ-H2AX Focus Formation Upon Treatment of Cells With UV Light and Alkylating Agents.

Published in:

Environmental & Molecular Mutagenesis, 2008, v. 49, n. 9, p. 734, doi. 10.1002/em.20430

By:

Staszewski, Ori;
Nikolova, Teodora;
Kaina, Bernd

Publication type:

Article

Autologous stem cell transplantation using modified TAM or combination of triple-alkylating agents conditioning regimens as one of the post-remission treatments in patients with adult acute myeloid leukemia in first complete remission.

Published in:

Bone Marrow Transplantation, 2004, v. 34, n. 3, p. 215, doi. 10.1038/sj.bmt.1704556

By:

Kim, H-J.;
Min, W-S.;
Eom, K-S.;
Park, S-J.;
Park, Y-H.;
Kim, D-W.;
Lee, J-W.;
Park, C-W.;
Kim, C-C.

Publication type:

Article

Design, synthesis, chemical and biological evaluation of brain targeted alkylating agent using reversible redox prodrug approach.

Published in:

Arabian Journal of Chemistry, 2017, v. 10, n. 3, p. 420, doi. 10.1016/j.arabjc.2013.12.008

By:

Singh, Rajesh K.;
Prasad, D. N.;
Bhardwaj, T. R.

Publication type:

Article

AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents

Published in:

FEBS Letters, 2013, v. 587, n. 2, p. 170, doi. 10.1016/j.febslet.2012.11.018

By:

Zhou, Jing;
Ng, Shukie;
Huang, Qing;
Wu, You-Tong;
Li, Zhengqiu;
Yao, Shao Q.;
Shen, Han-Ming

Publication type:

Article

Gemcitabine and oxaliplatin or alkylating agents for neuroendocrine tumors: Comparison of efficacy and search for predictive factors guiding treatment choice.

Published in:

2015

By:

Dussol, Anne‐Sophie;
Joly, Marie‐Odile;
Vercherat, Cecile;
Forestier, Julien;
Hervieu, Valérie;
Scoazec, Jean‐Yves;
Lombard‐Bohas, Catherine;
Walter, Thomas

Publication type:

journal article

Deregulation of homologous recombination DNA repair in alkylating agent-treated stem cell clones: a possible role in the aetiology of chemotherapy-induced leukaemia.

Published in:

Oncogene, 2006, v. 25, n. 12, p. 1709, doi. 10.1038/sj.onc.1209208

By:

Worrillow, L J;
Allan, J M

Publication type:

Article

Dose–Effect Relationship of Alkylating Agents on Testicular Function in Male Survivors of Childhood Lymphoma.

Published in:

Pediatric Hematology & Oncology, 2015, v. 32, n. 8, p. 613, doi. 10.3109/08880018.2015.1085933

By:

Servitzoglou, Marina;
De Vathaire, Florent;
Oberlin, Odile;
Patte, Catherine;
Thomas-Teinturier, Cécile

Publication type:

Article

Preparation and Chemical Behavior of 2‐(tert‐Butoxycarbonyl)amino‐3‐bromomethyl Pyridine, a Novel Alkylating Agent.

Published in:

Synthetic Communications, 2006, v. 36, n. 2, p. 181, doi. 10.1080/00397910500334371

By:

Krasavin, Mikhail;
Shkavrov, Sergey;
Kravchenko, Dmitry

Publication type:

Article

Alkylating Agent-Induced Toxicity and Melatonin-Based Therapies.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.873197

By:

Egea, Javier;
López-Muñoz, Francisco;
Fernández-Capetillo, Oscar;
Reiter, Russel J.;
Romero, Alejandro

Publication type:

Article

Stimulatory and Protective Effects of Alkylating Agents Applied in Ultra-Low Concentrations.

Published in:

Pharmacology, 2001, v. 62, n. 3, p. 129, doi. 10.1159/000056084

By:

Pukhalsky, Alexander L.;
Shmarina, Galina V.

Publication type:

Article

Development of validation of a rapid and simple analytical separation method for anticancer alkylating agents using application of total error concept.

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 2, p. 431, doi. 10.29228/jrp.140

By:

SOFIQUL, Islam;
MURUGAN, Vedigounder

Publication type:

Article

Novel Pathways of Oxidative and Nitrosative Inactivation of the Human MGMT Protein in Colon Cancer and Glioblastoma Cells: Increased Efficacy of Alkylating Agents In Vitro and In Vivo.

Published in:

Diseases, 2025, v. 13, n. 2, p. 32, doi. 10.3390/diseases13020032

By:

Basak, Debasish;
Mostofa, Agm;
Madala, Hanumantha Rao;
Srivenugopal, Kalkunte S.

Publication type:

Article

Human ALKBH6 Is Required for Maintenance of Genomic Stability and Promoting Cell Survival During Exposure of Alkylating Agents in Pancreatic Cancer.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.635808

By:

Zhao, Shengyuan;
Devega, Rodan;
Francois, Aaliyah;
Kidane, Dawit

Publication type:

Article

Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers.

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202203684

By:

Schilling, Danny;
Barayeu, Uladzimir;
Steimbach, Raphael R.;
Talwar, Deepti;
Miller, Aubry K.;
Dick, Tobias P.

Publication type:

Article

Rituximab, alkylating agents or combination therapy for gastric mucosa-associated lymphoid tissue lymphoma: a monocentric non-randomised observational study.

Published in:

Alimentary Pharmacology & Therapeutics, 2014, v. 39, n. 6, p. 619, doi. 10.1111/apt.12635

By:

Amiot, A.;
Lévy, M.;
Copie‐Bergman, C.;
Dupuis, J.;
Szablewski, V.;
Le Baleur, Y.;
Baia, M.;
Belhadj, K.;
Sobhani, I.;
Leroy, K.;
Haioun, C.;
Delchier, J‐C.

Publication type:

Article

Intracellular activation of 4-hydroxycyclophosphamide into a DNA-alkylating agent in human leucocytes.

Published in:

Xenobiotica, 2021, v. 51, n. 10, p. 1188, doi. 10.1080/00498254.2021.1975060

By:

Yong, Minghan;
Burns, Kathryn Elisa;
de Zoysa, Janak;
Helsby, Nuala Ann

Publication type:

Article

The Alkylating Agent Methyl Methanesulfonate Triggers Lipid Alterations at the Inner Nuclear Membrane That Are Independent from Its DNA-Damaging Ability.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7461, doi. 10.3390/ijms22147461

By:

Ovejero, Sara;
Soulet, Caroline;
Moriel-Carretero, María

Publication type:

Article

Histopathological investigation of the 1p/19q-codeleted gliomas resected following alkylating agent chemotherapy.

Published in:

Journal of Neuro-Oncology, 2021, v. 155, n. 3, p. 235, doi. 10.1007/s11060-021-03855-y

By:

Kanazawa, Tokunori;
Ohara, Kentaro;
Kitamura, Yohei;
Nakaya, Masato;
Yoshida, Kazunari;
Sasaki, Hikaru

Publication type:

Article