Works matching Acid ceramidase

Results: 212

Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges.

Published in:

Pharmaceutics, 2018, v. 10, n. 2, p. 45, doi. 10.3390/pharmaceutics10020045

By:

Nguyen, Ha S.;
Awad, Ahmed J.;
Shabani, Saman;
Doan, Ninh

Publication type:

Article

Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 3, p. 635, doi. 10.1007/s00280-012-2050-4

By:

Morad, Samy;
Messner, Maria;
Levin, Jonathan;
Abdelmageed, Noha;
Park, Hyejung;
Merrill, Alfred;
Cabot, Myles

Publication type:

Article

Signalling Effects Induced by Acid Ceramidase in Human Epithelial Or Leukemic Cell Lines.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 5, p. 1092, doi. 10.33594/000000074

By:

Baduva, Käthe;
Büchter, Lara;
Kreyenkamp, Katja;
Westphal, Linnea;
Wilker, Barbara;
Kohnen, Marcus;
Schuchman, Edward H.;
Edwards, Michael J.;
Becker, Katrin Anne;
Gulbins, Erich;
Carpinteiro, Alexander

Publication type:

Article

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.

Published in:

Cancers, 2023, v. 15, n. 24, p. 5866, doi. 10.3390/cancers15245866

By:

Ung, Johnson;
Tan, Su-Fern;
Fox, Todd E.;
Shaw, Jeremy J. P.;
Taori, Maansi;
Horton, Bethany J.;
Golla, Upendarrao;
Sharma, Arati;
Szulc, Zdzislaw M.;
Wang, Hong-Gang;
Chalfant, Charles E.;
Cabot, Myles C.;
Claxton, David F.;
Loughran Jr., Thomas P.;
Feith, David J.

Publication type:

Article

Fragment-Based Hologram QSAR Studies on a Series of2,4-Dioxopyrimidine-1-Carboxamides As Highly Potent Inhibitors of Acid Ceramidase.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, p. 139

By:

Xiang-Lin Yang;
Yuan Zhou;
Xin-Ling Liu

Publication type:

Article

Pharmacophore elucidation and 3D-QSAR analysis of a new class of highly potent inhibitors of acid ceramidase based on maximum common substructure and field fit alignment methods.

Published in:

Journal of the Iranian Chemical Society, 2014, v. 11, n. 5, p. 1329, doi. 10.1007/s13738-013-0402-6

By:

Pirhadi, Somayeh;
Shiri, Fereshteh;
Ghasemi, Jahan

Publication type:

Article

Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.

Published in:

Journal of Biochemistry, 2015, v. 158, n. 4, p. 309, doi. 10.1093/jb/mvv039

By:

Naoki Mizutani;
Minami Inoue;
Yukari Omori;
Hiromi Ito;
Keiko Tamiya-Koizumi;
Akira Takagi;
Tetsuhito Kojima;
Mitsuhiro Nakamura;
Soichiro Iwaki;
Masahiro Nakatochi;
Motoshi Suzuki;
Yoshinori Nozawa;
Takashi Murate

Publication type:

Article

Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 2, p. 485, doi. 10.1002/anie.201409042

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Inside Cover: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. Int. Ed. 2/2015).

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 2, p. 366, doi. 10.1002/anie.201410931

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Acid Ceramidase Promotes Nuclear Export of PTEN through Sphingosine 1-Phosphate Mediated Akt Signaling.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076593

By:

Beckham, Thomas H.;
Cheng, Joseph C.;
Lu, Ping;
Marrison, S. Tucker;
Norris, James S.;
Liu, Xiang

Publication type:

Article

Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062715

By:

Simonaro, Calogera M.;
Sachot, Sylvain;
Ge, Yi;
He, Xingxuan;
DeAngelis, Victor A.;
Eliyahu, Efrat;
Leong, Daniel J.;
Sun, Hui B.;
Mason, Jeffrey B.;
Haskins, Mark E.;
Richardson, Dean W.;
Schuchman, Edward H.

Publication type:

Article

Blockade of Lysosomal Acid Ceramidase Induces GluN2B-Dependent Tau Phosphorylation in Rat Hippocampal Slices.

Published in:

Neural Plasticity, 2014, v. 2014, p. 1, doi. 10.1155/2014/196812

By:

Laurier-Laurin, Marie-Elaine;
DeMontigny, Audrée;
Essis, Suzanne Attiori;
Cyr, Michel;
Massicotte, Guy

Publication type:

Article

Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177805

By:

Bai, Aiping;
Mao, Cungui;
Jenkins, Russell W.;
Szulc, Zdzislaw M.;
Bielawska, Alicja;
Hannun, Yusuf A.

Publication type:

Article

Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis.

Published in:

2020

By:

Gardner, Aaron I.;
Haq, Iram J.;
Simpson, A. John;
Becker, Katrin A.;
Gallagher, John;
Saint-Criq, Vinciane;
Verdon, Bernard;
Mavin, Emily;
Trigg, Alexandra;
Gray, Michael A.;
Koulman, Albert;
McDonnell, Melissa J.;
Fisher, Andrew J.;
Kramer, Elizabeth L.;
Clancy, John P.;
Ward, Christopher;
Schuchman, Edward H.;
Gulbins, Erich;
Brodlie, Malcolm

Publication type:

journal article

Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase.

Published in:

Angewandte Chemie, 2015, v. 127, n. 2, p. 495, doi. 10.1002/ange.201409042

By:

Pizzirani, Daniela;
Bach, Anders;
Realini, Natalia;
Armirotti, Andrea;
Mengatto, Luisa;
Bauer, Inga;
Girotto, Stefania;
Pagliuca, Chiara;
De Vivo, Marco;
Summa, Maria;
Ribeiro, Alison;
Piomelli, Daniele

Publication type:

Article

Acid ceramidase deficiency: Farber disease and SMA-PME.

Published in:

2018

By:

Yu, Fabian P. S.;
Amintas, Samuel;
Levade, Thierry;
Medin, Jeffrey A.

Publication type:

journal article

Construction of Conditional Acid Ceramidase Knockout Mice and in vivo Effects on Oocyte Development and Fertility.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2012, v. 30, n. 3, p. 735, doi. 10.1159/000341453

By:

Eliyahu, Efrat;
Shtraizent, Nataly;
Shalgi, Ruth;
Schuchman, Edward H.

Publication type:

Article

Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90219-1

By:

Lai, Michele;
Amato, Rachele;
La Rocca, Veronica;
Bilgin, Mesut;
Freer, Giulia;
Spezia, Piergiorgio;
Quaranta, Paola;
Piomelli, Daniele;
Pistello, Mauro

Publication type:

Article

Genetic Variation in Acid Ceramidase Predicts Non-completion of an Exercise Intervention.

Published in:

Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00781

By:

Lewis, Lauren S.;
Huffman, Kim M.;
Smith, Ira J.;
Donahue, Mark P.;
Slentz, Cris A.;
Houmard, Joseph A.;
Hubal, Monica J.;
Hoffman, Eric P.;
Hauser, Elizabeth R.;
Siegler, Ilene C.;
Kraus, William E.

Publication type:

Article

The molecular medicine of acid ceramidase.

Published in:

Biological Chemistry, 2015, v. 396, n. 6/7, p. 759, doi. 10.1515/hsz-2014-0290

By:

Frohbergh, Michael;
Xingxuan He;
Schuchman, Edward H.

Publication type:

Article

Acid ceramidase gene therapy ameliorates pulmonary arterial hypertension with right heart dysfunction.

Published in:

Respiratory Research, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12931-023-02487-2

By:

Katz, Michael G.;
Hadas, Yoav;
Vincek, Adam;
Freage-Kahn, Lina;
Shtraizent, Nataly;
Madjarov, Jeko M.;
Pastuszko, Peter;
Eliyahu, Efrat

Publication type:

Article

Decreased Sphingosine Due to Down-Regulation of Acid Ceramidase Expression in Airway of Bronchiectasis Patients: A Potential Contributor to Pseudomonas aeruginosa Infection.

Published in:

Infection & Drug Resistance, 2023, v. 16, p. 2573, doi. 10.2147/IDR.S407335

By:

Qi, Qian;
Xu, Jiawei;
Wang, Yujiao;
Zhang, Jian;
Gao, Mingxia;
Li, Yu;
Dong, Liang

Publication type:

Article

New insights on the use of desipramine as an inhibitor for acid ceramidase

Published in:

FEBS Letters, 2006, v. 580, n. 19, p. 4751, doi. 10.1016/j.febslet.2006.07.071

By:

Elojeimy, Saeed;
Holman, David H.;
Liu, Xiang;
El-Zawahry, Ahmed;
Villani, Maristella;
Cheng, Joseph C.;
Mahdy, Ayman;
Zeidan, Youssef;
Bielwaska, Alicja;
Hannun, Yusuf A.;
Norris, James S.

Publication type:

Article

Tamoxifen is a candidate first‐in‐class inhibitor of acid ceramidase that reduces amitotic division in polyploid giant cancer cells—Unrecognized players in tumorigenesis.

Published in:

Cancer Medicine, 2020, v. 9, n. 9, p. 3142, doi. 10.1002/cam4.2960

By:

White‐Gilbertson, Shai;
Lu, Ping;
Jones, Christian M.;
Chiodini, Stephanie;
Hurley, Deborah;
Das, Arabinda;
Delaney, Joe R.;
Norris, James S.;
Voelkel‐Johnson, Christina

Publication type:

Article

Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet β-cells

Published in:

FEBS Letters, 2009, v. 583, n. 12, p. 2136, doi. 10.1016/j.febslet.2009.05.047

By:

Zhu, Qun;
Shan, Xiaohong;
Miao, Heng;
Lu, Yibing;
Xu, Jiarong;
You, Na;
Liu, Chao;
Liao, Duan-fang;
Jin, Junfei

Publication type:

Article

Molecular Markers of Therapy-Resistant Glioblastoma and Potential Strategy to Combat Resistance.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1765, doi. 10.3390/ijms19061765

By:

Nguyen, Ha S.;
Shabani, Saman;
Awad, Ahmed J.;
Kaushal, Mayank;
Doan, Ninh

Publication type:

Article

Potential role of autophagy induced by FLT3-ITD and acid ceramidase in acute myeloid leukemia chemo-resistance: new insights.

Published in:

2022

By:

Zalpoor, Hamidreza;
Bakhtiyari, Maryam;
Akbari, Abdullatif;
Aziziyan, Fatemeh;
Shapourian, Hooriyeh;
Liaghat, Mahsa;
Zare-Badie, Zahra;
Yahyazadeh, Sheida;
Tarhriz, Vahideh;
Ganjalikhani-Hakemi, Mazdak

Publication type:

Literature Review

Overexpression and mass spectrometry analysis of mature human acid ceramidase.

Published in:

Biological Chemistry, 2007, v. 388, n. 12, p. 1333, doi. 10.1515/BC.2007.152

By:

Schulze, Heike;
Schepers, Ute;
Sandhoff, Konrad

Publication type:

Article

Pathological manifestations of Farber disease in a new mouse model.

Published in:

Biological Chemistry, 2018, v. 399, n. 10, p. 1183, doi. 10.1515/hsz-2018-0170

By:

Beckmann, Nadine;
Kadow, Stephanie;
Schumacher, Fabian;
Göthert, Joachim R.;
Kesper, Stefanie;
Draeger, Annette;
Schulz-Schaeffer, Walter J.;
Jiang Wang;
Becker, Jan U.;
Kramer, Melanie;
Kühn, Claudine;
Kleuser, Burkhard;
Becker, Katrin Anne;
Gulbins, Erich;
Carpinteiro, Alexander

Publication type:

Article

Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C<sub>6</sub> ceramide.

Published in:

Prostate Cancer & Prostatic Diseases, 2011, v. 14, n. 1, p. 30, doi. 10.1038/pcan.2010.47

By:

Turner, L. S.;
Cheng, J. C.;
Beckham, T. H.;
Keane, T. E.;
Norris, J. S.;
Liu, X.

Publication type:

Article

Acid ceramidase expression reduces IFNγ secretion by mouse CD4<sup>+</sup> T cells and is crucial for maintaining B-cell numbers in mice.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1309846

By:

Mandasari, Putri;
Hollmann, Claudia;
Zaidi, Rehan-Haider;
Löw, Samira;
Schrama, Jann;
Wigger, Dominik;
Schumacher, Fabian;
Kleuser, Burkhard;
Beyersdorf, Niklas

Publication type:

Article

Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis.

Published in:

Archives of Pharmacal Research, 2019, v. 42, n. 3, p. 232, doi. 10.1007/s12272-019-01114-3

By:

Cho, Sung Min;
Kwon, Ho Jeong

Publication type:

Article

Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00538-w

By:

Xiao, Juan;
Zeng, Wenying;
Zhang, Pengcheng;
Zhou, Yuan;
Fang, Qiangqiang

Publication type:

Article

Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 2, p. 231, doi. 10.1007/s00280-007-0465-0

By:

Holman, David H.;
Turner, Lorianne S.;
El-Zawahry, Ahmed;
Elojeimy, Saeed;
Xiang Liu;
Bielawski, Jacek;
Szulc, Zdzislaw M.;
Norris, Kristi;
Zeidan, Youssef H.;
Hannun, Yusuf A.;
Bielawska, Alicja;
Norris, James S.

Publication type:

Article

High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 343, doi. 10.1080/14756366.2022.2150183

By:

Aseeri, Mazen;
Abad, José Luis;
Delgado, Antonio;
Fabriàs, Gemma;
Triola, Gemma;
Casas, Josefina

Publication type:

Article

Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.

Published in:

International Journal of Cancer, 2016, v. 139, n. 6, p. 1372, doi. 10.1002/ijc.30171

By:

Korbelik, Mladen;
Banáth, Judit;
Zhang, Wei;
Saw, Kyi Min;
Szulc, Zdzislaw M.;
Bielawska, Alicja;
Separovic, Duska

Publication type:

Article

Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B.

Published in:

International Journal of Cancer, 2012, v. 131, n. 9, p. 2034, doi. 10.1002/ijc.27480

By:

Beckham, Thomas H.;
Lu, Ping;
Cheng, Joseph C.;
Zhao, Dan;
Turner, Lorianne S.;
Zhang, Xiaoyi;
Hoffman, Stanley;
Armeson, Kent E.;
Liu, Angen;
Marrison, Tucker;
Hannun, Yusuf A.;
Liu, Xiang

Publication type:

Article

Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling.

Published in:

Oncogenesis, 2013, v. 2, n. 6, p. 1, doi. 10.1038/oncsis.2013.14

By:

Beckham, T. H.;
J. C. Cheng;
P. Lu;
Y. Shao;
D. Troyer;
Lance, R.;
Marrison, S. T.;
Norris, J. S.;
X. Liu

Publication type:

Article

Acid Ceramidase Deficiency: Bridging Gaps between Clinical Presentation, Mouse Models, and Future Therapeutic Interventions.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 274, doi. 10.3390/biom13020274

By:

Kleynerman, Annie;
Rybova, Jitka;
Faber, Mary L.;
McKillop, William M.;
Levade, Thierry;
Medin, Jeffrey A.

Publication type:

Article

Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer.

Published in:

Climacteric, 2009, v. 12, n. 6, p. 502, doi. 10.3109/13697130902939913

By:

Ruckhäberle, E.;
Holtrich, U.;
Engels, K.;
Hanker, L.;
Gätje, R.;
Metzler, D.;
Karn, T.;
Kaufmann, M.;
Rody, A.

Publication type:

Article

Targeting Acid Ceramidase Inhibits Glioblastoma Cell Migration through Decreased AKT Signaling.

Published in:

Cells (2073-4409), 2022, v. 11, n. 12, p. 1873, doi. 10.3390/cells11121873

By:

Hawkins, Cyntanna C.;
Jones, Amber B.;
Gordon, Emily R.;
Williford, Sarah E.;
Harsh, Yuvika;
Ziebro, Julia K.;
Landis, Catherine J.;
Gc, Sajina;
Crossman, David K.;
Cooper, Sara J.;
Ramanadham, Sasanka;
Doan, Ninh;
Hjelmeland, Anita B.

Publication type:

Article

Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer.

Published in:

Cells (2073-4409), 2020, v. 9, n. 12, p. 2693, doi. 10.3390/cells9122693

By:

Clifford, Rachael E.;
Govindarajah, Naren;
Bowden, David;
Sutton, Paul;
Glenn, Mark;
Darvish-Damavandi, Mahnaz;
Buczacki, Simon;
McDermott, Ultan;
Szulc, Zdzislaw;
Ogretmen, Besim;
Parsons, Jason L.;
Vimalachandran, Dale

Publication type:

Article

Overexpression of the β-Subunit of Acid Ceramidase in the Epidermis of Mice Provokes Atopic Dermatitis-like Skin Symptoms.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8737, doi. 10.3390/ijms25168737

By:

Sashikawa-Kimura, Miho;
Takada, Mariko;
Hossain, Md Razib;
Tsuda, Hidetoshi;
Xie, Xiaonan;
Komine, Mayumi;
Ohtsuki, Mamitaro;
Imokawa, Genji

Publication type:

Article

Sphingomyelin Deacylase, the Enzyme Involved in the Pathogenesis of Atopic Dermatitis, Is Identical to the β-Subunit of Acid Ceramidase.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8789, doi. 10.3390/ijms21228789

By:

Teranishi, Yasuhiro;
Kuwahara, Hiroshi;
Ueda, Masaru;
Takemura, Tadashi;
Kusumoto, Masanori;
Nakamura, Keiji;
Sakai, Jun;
Kimura, Toru;
Furutani, Yasuji;
Kawashima, Makoto;
Imokawa, Genji;
Nogami-Itoh, Mari

Publication type:

Article

Acid Ceramidase Depletion Impairs Neuronal Survival and Induces Morphological Defects in Neurites Associated with Altered Gene Transcription and Sphingolipid Content.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1607, doi. 10.3390/ijms21051607

By:

Kyriakou, Kalia;
W. Lederer, Carsten;
Kleanthous, Marina;
Drousiotou, Anthi;
Malekkou, Anna

Publication type:

Article

Spinal Muscular Atrophy with Progressive Myoclonic Epilepsy (SMA-PME): three new cases and review of the mutational spectrum.

Published in:

Italian Journal of Pediatrics, 2023, v. 49, n. 1, p. 1, doi. 10.1186/s13052-023-01474-z

By:

Najafi, Ali;
Tasharrofi, Behnoosh;
Zandsalimi, Farshid;
Rasulinezhad, Maryam;
Ghahvechi Akbari, Masood;
Zamani, Gholamreza;
Ashrafi, Mahmoud Reza;
Heidari, Morteza

Publication type:

Article

Brief Report: Peripheral Osteolysis in Adults Linked to ASAH1 (Acid Ceramidase) Mutations: A New Presentation of Farber's Disease.

Published in:

Arthritis & Rheumatology, 2016, v. 68, n. 9, p. 2323, doi. 10.1002/art.39659

By:

Bonafé, Luisa;
Kariminejad, Ariana;
Li, Jia;
Royer‐Bertrand, Beryl;
Garcia, Virginie;
Mahdavi, Shokouholsadat;
Bozorgmehr, Bita;
Lachman, Ralph L.;
Mittaz‐Crettol, Lauréane;
Campos‐Xavier, Belinda;
Nampoothiri, Sheela;
Unger, Sheila;
Rivolta, Carlo;
Levade, Thierry;
Superti‐Furga, Andrea

Publication type:

Article

Acid ceramidase involved in pathogenic cascade leading to accumulation of α-synuclein in iPSC model of GBA1-associated Parkinson's disease.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 11, p. 1888, doi. 10.1093/hmg/ddad025

By:

Kumar, Manoj;
Srikanth, Manasa P;
Deleidi, Michela;
Hallett, Penelope J;
Isacson, Ole;
Feldman, Ricardo A

Publication type:

Article

Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 11, p. 1972, doi. 10.1093/hmg/ddy105

By:

Myung Jong Kim;
Jeon, Sohee;
Burbulla, Lena F.;
Krainc, Dimitri

Publication type:

Article

Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.

Published in:

Science Translational Medicine, 2020, v. 12, n. 557, p. 1, doi. 10.1126/scitranslmed.aay8798

By:

Alsamman, Sarah;
Christenson, Stephanie A.;
Yu, Amy;
Ayad, Nadia M. E.;
Mooring, Meghan S.;
Segal, Joe M.;
Hu, Jimmy Kuang-Hsien;
Schaub, Johanna R.;
Ho, Steve S.;
Rao, Vikram;
Marlow, Megan M.;
Turner, Scott M.;
Sedki, Mai;
Pantano, Lorena;
Ghoshal, Sarani;
Ferreira, Diego Dos Santos;
Ma, Hsiao-Yen;
Duwaerts, Caroline C.;
Espanol-Suner, Regina;
Wei, Lan

Publication type:

Article