Works by van der Vlag, Johan

Results: 79

Heparanase-2 protein and peptides have a protective effect on experimental glomerulonephritis and diabetic nephropathy.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1098184

By:

Buijsers, Baranca;
Garsen, Marjolein;
de Graaf, Mark;
Bebber, Marinka Bakker-van;
Chunming Guo;
Xue Li;
van der Vlag, Johan

Publication type:

Article

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01433

By:

Luo, Wentian;
Olaru, Florina;
Miner, Jeffrey H.;
Beck Jr, Laurence H.;
van der Vlag, Johan;
Thurman, Joshua M.;
Borza, Dorin-Bogdan

Publication type:

Article

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00989

By:

Biermann, Mona H. C.;
Boeltz, Sebastian;
Pieterse, Elmar;
Knopf, Jasmin;
Rech, Jürgen;
Bilyy, Rostyslav;
van der Vlag, Johan;
Tincani, Angela;
Distler, Jörg H. W.;
Krönke, Gerhard;
Schett, Georg Andreas;
Herrmann, Martin;
Muñoz, Luis E.

Publication type:

Article

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 10, p. 1236, doi. 10.1038/nsmb1013-1236b

By:

Erkek, Serap;
Hisano, Mizue;
Liang, Ching-Yeu;
Gill, Mark;
Murr, Rabih;
Dieker, Jürgen;
Schübeler, Dirk;
van der Vlag, Johan;
Stadler, Michael B;
Peters, Antoine H F M

Publication type:

Article

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 868, doi. 10.1038/nsmb.2599

By:

Erkek, Serap;
Hisano, Mizue;
Liang, Ching-Yeu;
Gill, Mark;
Murr, Rabih;
Dieker, Jürgen;
Schübeler, Dirk;
Vlag, Johan van der;
Stadler, Michael B;
Peters, Antoine H F M

Publication type:

Article

Errata.

Published in:

2021

By:

Braanker, Dirk J W den;
Maas, Rutger J;
Deegens, Jeroen K;
Yanginlar, Cansu;
Wetzels, Jack F M;
van der Vlag, Johan;
Nijenhuis, Tom

Publication type:

Correction Notice

Novel in vitro assays to detect circulating permeability factor(s) in idiopathic focal segmental glomerulosclerosis.

Published in:

Nephrology Dialysis Transplantation, 2021, v. 36, n. 2, p. 247, doi. 10.1093/ndt/gfaa211

By:

Braanker, Dirk J W den;
Maas, Rutger J;
Deegens, Jeroen K;
Yanginlar, Cansu;
Wetzels, Jack F M;
van der Vlag, Johan;
Nijenhuis, Tom

Publication type:

Article

The role of heparanase and the endothelial glycocalyx in the development of proteinuria.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 1, p. 49, doi. 10.1093/ndt/gft410

By:

Garsen, Marjolein;
Rops, Angelique L.W.M.M.;
Rabelink, Ton J.;
Berden, Jo H.M.;
van der Vlag, Johan

Publication type:

Article

New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 7, p. 1830, doi. 10.1093/ndt/gfs572

By:

Hofstra, Julia M.;
Lainez, Sergio;
van Kuijk, Willie H.M.;
Schoots, Jeroen;
Baltissen, Marijke P.A.;
Hoefsloot, Lies H.;
Knoers, Nine V.A.M.;
Berden, Jo H.M.;
Bindels, René J.M.;
van der Vlag, Johan;
Hoenderop, Joost G.J.;
Wetzels, Jack F.M.;
Nijenhuis, Tom

Publication type:

Article

Urinary heparanase activity in patients with Type 1 and Type 2 diabetes.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 7, p. 2853, doi. 10.1093/ndt/gfr732

By:

Rops, Angelique L.W.M.M.;
van den Hoven, Mabel J.;
Veldman, Bart A.;
Salemink, Simone;
Vervoort, Gerald;
Elving, Lammy D.;
Aten, Jan;
Wetzels, Jack F.;
van der Vlag, Johan;
Berden, Jo H.M.

Publication type:

Article

Protein Expression Correlates Linearly with mRNA Dose over Up to Five Orders of Magnitude In Vitro and In Vivo.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 511, doi. 10.3390/biomedicines9050511

By:

van Asbeck, Alexander H.;
Dieker, Jürgen;
Oude Egberink, Rik;
van den Berg, Lennard;
van der Vlag, Johan;
Brock, Roland;
García-Díaz, María

Publication type:

Article

Inhibition of mTOR delayed but could not prevent experimental collapsing focal segmental glomerulosclerosis.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65352-y

By:

Miesen, Laura;
Eymael, Jennifer;
Sharma, Shagun;
Loeven, Markus A.;
Willemsen, Brigith;
Bakker-van Bebber, Marinka;
Mooren, Fieke;
Meyer-Schwesinger, Catherine;
Dijkman, Henry;
Wetzels, Jack F. M.;
Jansen, Jitske;
van der Vlag, Johan;
Smeets, Bart

Publication type:

Article

Heparanase Is a Putative Mediator of Endothelial Glycocalyx Damage in COVID-19 – A Proof-of-Concept Study.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.916512

By:

Drost, Carolin Christina;
Rovas, Alexandros;
Osiaevi, Irina;
Rauen, Matthias;
van der Vlag, Johan;
Buijsers, Baranca;
Salmenov, Rustem;
Lukasz, Alexander;
Pavenstädt, Hermann;
Linke, Wolfgang A.;
Kümpers, Philipp

Publication type:

Article

Microparticles in Autoimmunity: Cause or Consequence of Disease?

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.822995

By:

Rother, Nils;
Yanginlar, Cansu;
Pieterse, Elmar;
Hilbrands, Luuk;
van der Vlag, Johan

Publication type:

Article

Vitamin D attenuates proteinuria by inhibition of heparanase expression in the podocyte.

Published in:

Journal of Pathology, 2015, v. 237, n. 4, p. 472, doi. 10.1002/path.4593

By:

Garsen, Marjolein;
Sonneveld, Ramon;
Rops, Angelique LWMM;
Huntink, Suzanne;
van Kuppevelt, Toin H;
Rabelink, Ton J;
Hoenderop, Joost GJ;
Berden, Jo HM;
Nijenhuis, Tom;
van der Vlag, Johan

Publication type:

Article

Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration.

Published in:

Journal of Pathology, 2013, v. 229, n. 5, p. 645, doi. 10.1002/path.4125

By:

Smeets, Bart;
Boor, Peter;
Dijkman, Henry;
Sharma, Shagun V;
Jirak, Peggy;
Mooren, Fieke;
Berger, Katja;
Bornemann, Jörg;
Gelman, Irwin H;
Floege, Jürgen;
van der Vlag, Johan;
Wetzels, Jack FM;
Moeller, Marcus J

Publication type:

Article

Lupus Nephritis: Enigmas, Conflicting Models and an Emerging Concept.

Published in:

Molecular Medicine, 2013, v. 19, n. 2, p. 161, doi. 10.2119/molmed.2013.00010

By:

Seredkina, Natalya;
van der Vlag, Johan;
Berden, Jo;
Mortensen, Elin;
Rekvig, Ole Petter

Publication type:

Article

Apoptosis and NET formation in the pathogenesis of SLE.

Published in:

Autoimmunity, 2012, v. 45, n. 8, p. 597, doi. 10.3109/08916934.2012.719953

By:

Bouts, Yvette M.;
Wolthuis, David F.G.J.;
Dirkx, Michiel F.M.;
Pieterse, Elmar;
Simons, Esther M.F.;
Van Boekel, Anna M.;
Dieker, Jürgen W.;
Van Der Vlag, Johan

Publication type:

Article

Effect of administration of apoptotic blebs on disease development in lupus mice.

Published in:

Autoimmunity, 2012, v. 45, n. 4, p. 290, doi. 10.3109/08916934.2012.664668

By:

Fransen, Justin H.;
Berden, Jo H.;
Koeter, Claudia M.;
Adema, Gosse J.;
Van Der Vlag, Johan;
Hilbrands, Luuk B.

Publication type:

Article

Regulatory and pathogenetic mechanisms of autoantibodies in SLE.

Published in:

Autoimmunity, 2011, v. 44, n. 5, p. 349, doi. 10.3109/08916934.2010.536794

By:

Radic, Marko;
Herrmann, Martin;
van der Vlag, Johan;
Rekvig, Ole Petter

Publication type:

Article

Nephritogenic antibodies bind in glomeruli through interaction with exposed chromatin fragments and not with renal cross-reactive antigens.

Published in:

Autoimmunity, 2011, v. 44, n. 5, p. 373, doi. 10.3109/08916934.2010.541170

By:

Mjelle, Janne Erikke;
Rekvig, Ole Petter;
Van Der Vlag, Johan;
Fenton, Kristin A.

Publication type:

Article

Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice.

Published in:

Arthritis Research & Therapy, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13075-015-0617-2

By:

Dieker, Jürgen;
Hilbrands, Luuk;
Thielen, Astrid;
Dijkman, Henry;
Berden, Jo H.;
van der Vlag, Johan

Publication type:

Article

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0168981

By:

Maicas, Nuria;
van der Vlag, Johan;
Bublitz, Janin;
Florquin, Sandrine;
Bakker-van Bebber, Marinka;
Dinarello, Charles A.;
Verweij, Vivienne;
Masereeuw, Roos;
Joosten, Leo A.;
Hilbrands, Luuk B.

Publication type:

Article

Direct Observation of Enhanced Nitric Oxide in a Murine Model of Diabetic Nephropathy.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170065

By:

Boels, Margien G. S.;
van Faassen, Ernst E. H.;
Avramut, M. Cristina;
van der Vlag, Johan;
van den Berg, Bernard M.;
Rabelink, Ton J.

Publication type:

Article

RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167336

By:

van Gemst, Jasper J.;
Loeven, Markus A.;
de Graaf, Mark J. J.;
Berden, Jo H. M.;
Rabelink, Ton J.;
Smit, Cornelis H.;
van der Vlag, Johan

Publication type:

Article

Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165373

By:

Dieker, Jürgen;
Berden, Jo H.;
Bakker, Marinka;
Briand, Jean-Paul;
Muller, Sylviane;
Voll, Reinhard;
Sjöwall, Christopher;
Herrmann, Martin;
Hilbrands, Luuk B.;
van der Vlag, Johan

Publication type:

Article

Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160894

By:

Garsen, Marjolein;
Rops, Angelique L.;
Li, Jinhua;
van Beneden, Katrien;
van den Branden, Christiane;
Berden, Jo HM;
Rabelink, Ton J.;
van der Vlag, Johan

Publication type:

Article

Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation.

Published in:

Nature Genetics, 2007, v. 39, n. 2, p. 251, doi. 10.1038/ng1949

By:

van der Heijden, Godfried W.;
Derijck, Alwin A. H. A.;
Pósfai, Eszter;
Giele, Maud;
Pelczar, Pawel;
Ramos, Liliana;
Wansink, Derick G.;
van der Vlag, Johan;
Peters, Antoine H. F. M.;
de Boer, Peter

Publication type:

Article

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation.

Published in:

Nature Genetics, 1999, v. 23, n. 4, p. 474, doi. 10.1038/70602

By:

van der Vlag, Johan;
Otte, Arie P.

Publication type:

Article

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.

Published in:

2016

By:

Boels, Margien G. S.;
Avramut, M. Cristina;
Koudijs, Angela;
Dane, Martijn J. C.;
Dae Hyun Lee;
van der Vlag, Johan;
Koster, Abraham J.;
van Zonneveld, Anton Jan;
van Faassen, Ernst;
Gröne, Hermann-Josef;
van den Berg, Bernard M.;
Rabelink1, Ton J.;
Lee, Dae Hyun;
Rabelink, Ton J

Publication type:

journal article

Expression of sialidase and dystroglycan in human glomerular diseases.

Published in:

Nephrology Dialysis Transplantation, 2010, v. 25, n. 2, p. 478, doi. 10.1093/ndt/gfp465

By:

Vogtländer, Nils P. J.;
Van der Vlag, Johan;
Bakker, Marinka A. H.;
Dijkman, Henry B.;
Wevers, Ron A.;
Campbell, Kevin P.;
Wetzels, Jack F. M.;
Berden, Jo H. M.

Publication type:

Article

Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species.

Published in:

Nephrology Dialysis Transplantation, 2009, v. 24, n. 9, p. 2637, doi. 10.1093/ndt/gfp182

By:

Van den Hoven, Mabel J.;
Waanders, Femke;
Rops, Angelique L.;
Kramer, Andrea B.;
Van Goor, Harry;
Berden, Jo H.;
Navis, Gerjan;
Van der Vlag, Johan

Publication type:

Article

Proteasome inhibition: a new therapeutic option in lupus nephritis?

Published in:

Nephrology Dialysis Transplantation, 2008, v. 23, n. 12, p. 3771, doi. 10.1093/ndt/gfn536

By:

Johan van der Vlag;
Jo H. M. Berden

Publication type:

Article

Adult and paediatric patients with minimal change nephrotic syndrome show no major alterations in glomerular expression of sulphated heparan sulphate domains.

Published in:

Nephrology Dialysis Transplantation, 2007, v. 22, n. 10, p. 2886

By:

Tessa J. M. Wijnhoven;
Joyce M. Geelen;
Marinka Bakker;
Joost F. M. Lensen;
Angelique L. W. M. M. Rops;
Andrea B. Kramer;
Gerjan Navis;
Mabel J. W. van den Hoven;
Johan van der Vlag;
Jo H. M. Berden;
Jack F. M. Wetzels;
Lambert P. W. J. van den Heuvel;
Leo A. H. Monnens;
Toin H. van Kuppevelt

Publication type:

Article

Expression of glomerular heparan sulphate domains in murine and human lupus nephritis.

Published in:

Nephrology Dialysis Transplantation, 2007, v. 22, n. 8, p. 2416, doi. 10.1093/ndt/gfm530

By:

Angelique L. Rops;
Mabel J. van den Hoven;
Marinka A. Bakker;
Joost F. Lensen;
Tessa J. Wijnhoven;
Lambert P. van den Heuvel;
Toin H. van Kuppevelt;
Johan van der Vlag;
Jo H. Berden

Publication type:

Article

Expression of glomerular heparan sulphate domains in murine and human lupus nephritis.

Published in:

Nephrology Dialysis Transplantation, 2007, v. 22, n. 7, p. 1891, doi. 10.1093/ndt/gfm194

By:

Rops, Angelique L.;
Van den Hoven, Mabel J.;
Bakker, Marinka A.;
Lensen, Joost F.;
Wijnhoven, Tessa J.;
Van den Heuvel, Lambert P.;
Van Kuppevelt, Toin H.;
Van der Vlag, Johan;
Berden, Jo H.

Publication type:

Article

Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes.

Published in:

Nephrology Dialysis Transplantation, 2007, v. 22, n. 4, p. 1070, doi. 10.1093/ndt/gfl801

By:

Angelique L. Rops;
Cor W. Jacobs;
Peter C. Linssen;
Jan B. Boezeman;
Joost F. Lensen;
Tessa J. Wijnhoven;
Lambert P. van den Heuvel;
Toin H. van Kuppevelt;
Johan van der Vlag;
Jo H. Berden

Publication type:

Article

Deranged removal of apoptotic cells: its role in the genesis of lupus.

Published in:

Nephrology Dialysis Transplantation, 2004, v. 19, n. 2, p. 282, doi. 10.1093/ndt/gfg485

By:

Jürgen W. C. Dieker;
Johan van der Vlag;
Jo H. M. Berden

Publication type:

Article

Microvascular differences in individuals with obesity at risk of developing cardiovascular disease.

Published in:

2021

By:

van der Velden, Anouk I. M.;
van den Berg, Bernard M.;
de Mutsert, Renée;
van der Vlag, Johan;
Jukema, J. Wouter;
Rosendaal, Frits R.;
Rabelink, Ton J.;
Vink, Hans

Publication type:

journal article

Neutrophil Extracellular Traps in Dengue Are Mainly Generated NOX-Independently.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. 1, doi. 10.3389/fimmu.2021.629167

By:

Garishah, Fadel Muhammad;
Rother, Nils;
Riswari, Silvita Fitri;
Alisjahbana, Bachti;
Overheul, Gijs J.;
van Rij, Ronald P.;
van der Ven, André;
van der Vlag, Johan;
de Mast, Quirijn

Publication type:

Article

Neutrophils Discriminate Between Lipopolysaccharides of Different Bacterial Sources and Selectively Release Neutrophil Extracellular Traps.

Published in:

Frontiers in Immunology, 2016, v. 7, p. 1, doi. 10.3389/fimmu.2016.00484

By:

Pieterse, Elmar;
Rother, Nils;
Yanginlar, Cansu;
Hilbrands, Luuk B.;
van der Vlag, Johan

Publication type:

Article

Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus.

Published in:

Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00610

By:

Rother, Nils;
van der Vlag, Johan;
Zhibin Chen;
MacDonald, Kelli Patricia Anne

Publication type:

Article

Editorial: Antimicrobial peptides and complement - maximising the inflammatory response.

Published in:

2015

By:

Stover, Cordula M.;
Van Der Vlag, Johan

Publication type:

Editorial

Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0189485

By:

de Groot, Theun;
Damen, Lars;
Kosse, Leanne;
Alsady, Mohammad;
Doty, Rosalinda;
Baumgarten, Ruben;
Sheehan, Susan;
van der Vlag, Johan;
Korstanje, Ron;
Deen, Peter M. T.

Publication type:

Article

Kidney tubule iron loading in experimental focal segmental glomerulosclerosis.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05261-4

By:

van Swelm, Rachel P. L.;
Beurskens, Sanne;
Dijkman, Henry;
Wiegerinck, Erwin T. G.;
Roelofs, Rian;
Thévenod, Frank;
van der Vlag, Johan;
Wetzels, Jack F. M.;
Swinkels, Dorine W.;
Smeets, Bart

Publication type:

Article

Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype.

Published in:

Biosensors (2079-6374), 2023, v. 13, n. 3, p. 339, doi. 10.3390/bios13030339

By:

't Hart, Daan C.;
Yildiz, Dilemin;
Palacio-Castañeda, Valentina;
Li, Lanhui;
Gumuscu, Burcu;
Brock, Roland;
Verdurmen, Wouter P. R.;
van der Vlag, Johan;
Nijenhuis, Tom

Publication type:

Article

Novel mouse strains to study circulating permeability factor(s) in primary focal segmental glomerulosclerosis.

Published in:

PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0274959

By:

den Braanker, Dirk;
Maas, Rutger;
Parr, Naomi;
Deegens, Jeroen;
Smeets, Bart;
Wetzels, Jack;
van der Vlag, Johan;
Nijenhuis, Tom

Publication type:

Article

A Putative Role for TRPC6 in Immune-Mediated Kidney Injury.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 22, p. 16419, doi. 10.3390/ijms242216419

By:

't Hart, Daan C.;
van der Vlag, Johan;
Nijenhuis, Tom

Publication type:

Article

Primary Focal Segmental Glomerulosclerosis Plasmas Increase Lipid Droplet Formation and Perilipin-2 Expression in Human Podocytes.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 194, doi. 10.3390/ijms24010194

By:

den Braanker, Dirk J. W.;
Maas, Rutger J. H.;
van Mierlo, Guido;
Parr, Naomi M. J.;
Bakker-van Bebber, Marinka;
Deegens, Jeroen K. J.;
Jansen, Pascal W. T. C.;
Gloerich, Jolein;
Willemsen, Brigith;
Dijkman, Henry B.;
van Gool, Alain J.;
Wetzels, Jack F. M.;
Rinschen, Markus M.;
Vermeulen, Michiel;
Nijenhuis, Tom;
van der Vlag, Johan

Publication type:

Article

Repurposing Riociguat to Target a Novel Paracrine Nitric Oxide-TRPC6 Pathway to Prevent Podocyte Injury.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12485, doi. 10.3390/ijms222212485

By:

't Hart, Daan;
Li, Jinhua;
van der Vlag, Johan;
Nijenhuis, Tom

Publication type:

Article