Works by van den Akker, Emile

Results: 30

Differentiating erythroblasts adapt to mechanical stimulation by upregulation of cholesterol biosynthesis via S1P/SREBP-induced HMGCR expression.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81746-8
By:
- Iacono, Giulia;
- Abay, Asena;
- Murillo, Joan S. Gallego;
- Aglialoro, Francesca;
- Yagci, Nurcan;
- Varga, Eszter;
- Bijlsma, Tieme;
- Sohler, Justine;
- Fu, Kerly;
- Reisz, Julie A.;
- Argabright, Amy;
- D'Alessandro, Angelo;
- Svendsen, Arthur F.;
- von Lindern, Marieke;
- van den Akker, Emile
Publication type:
Article
Rapid, Sensitive, and Specific Severe Acute Respiratory Syndrome Coronavirus 2 Detection: A Multicenter Comparison Between Standard Quantitative Reverse-Transcriptase Polymerase Chain Reaction and CRISPR-Based DETECTR.
Published in:
2021
By:
- Brandsma, Eelke;
- Verhagen, Han J M P;
- Laar, Thijs J W van de;
- Claas, Eric C J;
- Cornelissen, Marion;
- van den Akker, Emile;
- van de Laar, Thijs J W
Publication type:
Journal Article
Human‐induced pluripotent stem cell‐derived blood products: state of the art and future directions.
Published in:
FEBS Letters, 2019, v. 593, n. 23, p. 3288, doi. 10.1002/1873-3468.13599
By:
- Hansen, Marten;
- von Lindern, Marieke;
- van den Akker, Emile;
- Varga, Eszter
Publication type:
Article
Reduced myeloid commitment and increased uptake by macrophages of stem cell-derived HPS2 neutrophils.
Published in:
Life Science Alliance, 2024, v. 7, n. 4, p. 1, doi. 10.26508/lsa.202302263
By:
- Webbers, Steven D. S.;
- Aarts, Cathelijn E. M.;
- Klein, Bart;
- Koops, Dané;
- Geissler, Judy;
- Tool, Anton T. J.;
- van Bruggen, Robin;
- van den Akker, Emile;
- Kuijpers, Taco W.
Publication type:
Article
GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06090-z
By:
- Venhuizen, Jeron;
- van Bergen, Maaike G. J. M.;
- Bergevoet, Saskia M.;
- Gilissen, Daan;
- Spruijt, Cornelia G.;
- Wingens, Laura;
- van den Akker, Emile;
- Vermeulen, Michiel;
- Jansen, Joop H.;
- Martens, Joost H. A.;
- van der Reijden, Bert A.
Publication type:
Article
Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts.
Published in:
Frontiers in Physiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.00958
By:
- Aglialoro, Francesca;
- Hofsink, Naomi;
- Hofman, Menno;
- Brandhorst, Nicole;
- van den Akker, Emile
Publication type:
Article
Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04126-6
By:
- Heshusius, Steven;
- Grech, Laura;
- Gillemans, Nynke;
- Brouwer, Rutger W. W.;
- den Dekker, Xander T.;
- van IJcken, Wilfred F. J.;
- Nota, Benjamin;
- Felice, Alex E.;
- van Dijk, Thamar B.;
- von Lindern, Marieke;
- Borg, Joseph;
- van den Akker, Emile;
- Philipsen, Sjaak
Publication type:
Article
Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97149-y
By:
- Eernstman, Jesse;
- Veldhuisen, Barbera;
- Ligthart, Peter;
- von Lindern, Marieke;
- van der Schoot, C. Ellen;
- van den Akker, Emile
Publication type:
Article
Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95291-1
By:
- Mattebo, Alexander;
- Sen, Taha;
- Jassinskaja, Maria;
- Pimková, Kristýna;
- Prieto González-Albo, Isabel;
- Alattar, Abdul Ghani;
- Ramakrishnan, Ramprasad;
- Lang, Stefan;
- Järås, Marcus;
- Hansson, Jenny;
- Soneji, Shamit;
- Singbrant, Sofie;
- van den Akker, Emile;
- Flygare, Johan
Publication type:
Article
Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08705-0
By:
- Lopez-Yrigoyen, Martha;
- Yang, Cheng-Tao;
- Fidanza, Antonella;
- Cassetta, Luca;
- Taylor, A. Helen;
- McCahill, Angela;
- Sellink, Erica;
- von Lindern, Marieke;
- van den Akker, Emile;
- Mountford, Joanne C.;
- Pollard, Jeffrey W.;
- Forrester, Lesley M.
Publication type:
Article
Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocytes.
Published in:
EJNMMI Research, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13550-021-00823-5
By:
- Blom, Thomas;
- Meinsma, Rutger;
- di Summa, Franca;
- van den Akker, Emile;
- van Kuilenburg, André B. P.;
- Hansen, Marten;
- Tytgat, Godelieve A. M.
Publication type:
Article
Glutaraldehyde – A Subtle Tool in the Investigation of Healthy and Pathologic Red Blood Cells.
Published in:
Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00514
By:
- Abay, Asena;
- Simionato, Greta;
- Chachanidze, Revaz;
- Bogdanova, Anna;
- Hertz, Laura;
- Bianchi, Paola;
- van den Akker, Emile;
- von Lindern, Marieke;
- Leonetti, Marc;
- Minetti, Giampaolo;
- Wagner, Christian;
- Kaestner, Lars
Publication type:
Article
The Shape Shifting Story of Reticulocyte Maturation.
Published in:
Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.00829
By:
- Ovchynnikova, Elina;
- Aglialoro, Francesca;
- von Lindern, Marieke;
- van den Akker, Emile
Publication type:
Article
The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1416, doi. 10.3390/ijms25031416
By:
- Petkova-Kirova, Polina;
- Murciano, Nicoletta;
- Iacono, Giulia;
- Jansen, Julia;
- Simionato, Greta;
- Qiao, Min;
- van der Zwaan, Carmen;
- Rotordam, Maria Giustina;
- John, Thomas;
- Hertz, Laura;
- Hoogendijk, Arjan J.;
- Becker, Nadine;
- Wagner, Christian;
- von Lindern, Marieke;
- Egee, Stephane;
- van den Akker, Emile;
- Kaestner, Lars
Publication type:
Article
Mechanical Stress Induces Ca 2+ -Dependent Signal Transduction in Erythroblasts and Modulates Erythropoiesis.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 955, doi. 10.3390/ijms22020955
By:
- Aglialoro, Francesca;
- Abay, Asena;
- Yagci, Nurcan;
- Rab, Minke A. E.;
- Kaestner, Lars;
- van Wijk, Richard;
- von Lindern, Marieke;
- van den Akker, Emile
Publication type:
Article
The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene Expression.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 967, doi. 10.3390/ijms21030967
By:
- Hansen, Marten;
- Zeddies, Sabrina;
- Meinders, Marjolein;
- di Summa, Franca;
- Rollmann, Ewa;
- van Alphen, Floris P.J.;
- Hoogendijk, Arjan J.;
- Moore, Kat S.;
- Halbach, Melanie;
- Gutiérrez, Laura;
- van den Biggelaar, Maartje;
- Thijssen-Timmer, Daphne C.;
- Auburger, Georg W.J.;
- van den Akker, Emile;
- von Lindern, Marieke
Publication type:
Article
Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts.
Published in:
Frontiers in Neurology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.00958
By:
- Aglialoro, Francesca;
- Hofsink, Naomi;
- Hofman, Menno;
- Brandhorst, Nicole;
- van den Akker, Emile
Publication type:
Article
SMIM1 underlies the Vel blood group and influences red blood cell traits.
Published in:
Nature Genetics, 2013, v. 45, n. 5, p. 542, doi. 10.1038/ng.2603
By:
- Cvejic, Ana;
- Haer-Wigman, Lonneke;
- Stephens, Jonathan C;
- Kostadima, Myrto;
- Smethurst, Peter A;
- Frontini, Mattia;
- van den Akker, Emile;
- Bertone, Paul;
- Bielczyk-Maczyńska, Ewa;
- Farrow, Samantha;
- Fehrmann, Rudolf S N;
- Gray, Alan;
- de Haas, Masja;
- Haver, Vincent G;
- Jordan, Gregory;
- Karjalainen, Juha;
- Kerstens, Hindrik H D;
- Kiddle, Graham;
- Lloyd-Jones, Heather;
- Needs, Malcolm
Publication type:
Article
The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity.
Published in:
Biological Chemistry, 2004, v. 385, n. 5, p. 409, doi. 10.1515/BC.2004.045
By:
- Van den Akker, Emile;
- Van Dijk, Thamar B.;
- Schmidt, Uwe;
- Felida, Lamberto;
- Beug, Hartmut;
- Löwenberg, Bob;
- Von Lindern, Marieke
Publication type:
Article
Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors.
Published in:
Biotechnology & Bioengineering, 2022, v. 119, n. 11, p. 3096, doi. 10.1002/bit.28193
By:
- Gallego‐Murillo, Joan Sebastián;
- Iacono, Giulia;
- van der Wielen, Luuk A. M.;
- van den Akker, Emile;
- von Lindern, Marieke;
- Wahl, Sebastian Aljoscha
Publication type:
Article
Trichothiodystrophy causative TFIIEβ mutation affects transcription in highly differentiated tissue.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 23, p. 4689, doi. 10.1093/hmg/ddx351
By:
- Theil, Arjan F.;
- Mandemaker, Imke K.;
- van den Akker, Emile;
- Swagemakers, Sigrid M. A.;
- Raams, Anja;
- Wüst, Tatjana;
- Marteijn, Jurgen A.;
- Giltay, Jacques C.;
- Colombijn, Richard M.;
- Moog, Ute;
- Kotzaeridou, Urania;
- Ghazvini, Mehrnaz;
- von Lindern, Marieke;
- Hoeijmakers, Jan H. J.;
- Jaspers, Nicolaas G. J.;
- van der Spek, Peter J.;
- Vermeulen, Wim
Publication type:
Article
CD14+ monocytes repress gamma globin expression at early stages of erythropoiesis.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81060-7
By:
- Heshusius, Steven;
- Heideveld, Esther;
- von Lindern, Marieke;
- van den Akker, Emile
Publication type:
Article
Circular RNA expression in human hematopoietic cells is widespread and cell-type specific.
Published in:
Nucleic Acids Research, 2018, v. 46, n. 16, p. 8168, doi. 10.1093/nar/gky721
By:
- Nicolet, Benoit P;
- Engels, Sander;
- Aglialoro, Francesca;
- van den Akker, Emile;
- von Lindern, Marieke;
- Wolkers, Monika C
Publication type:
Article
Identification of a novel single-nucleotide mutation in SMIM1 gene that results in low Vel antigen expression.
Published in:
2019
By:
- Rijst, Marea V.E.;
- Voorn, Lesley;
- Veldhuisen, Barbera;
- Jongerius, John M.;
- Akker, Emile;
- Schoot, C. Ellen;
- van der Rijst, Marea V E;
- van den Akker, Emile;
- van der Schoot, C Ellen
Publication type:
journal article
Development of a recombinant anti-Vel immunoglobulin M to identify Vel-negative donors.
Published in:
2019
By:
- van der Rijst, Marea V.E.;
- Lissenberg‐Thunnissen, Suzanne N.;
- Ligthart, Peter C.;
- Visser, Remco;
- Jongerius, John M.;
- Voorn, Lesley;
- Veldhuisen, Barbera;
- Vidarsson, Gestur;
- van den Akker, Emile;
- van der Schoot, C. Ellen;
- Lissenberg-Thunnissen, Suzanne N
Publication type:
journal article
A variant RhAG protein encoded by the RHAG*572A allele causes serological weak D expression while maintaining normal RhCE phenotypes.
Published in:
2019
By:
- Wen, Jizhi;
- Verhagen, Onno J.H.M.;
- Jia, Shuangshuang;
- Liang, Qianni;
- Wang, Zhen;
- Wei, Ling;
- Luo, Hong;
- Luo, Guangping;
- Vidarsson, Gestur;
- Akker, Emile;
- Ji, Yanli;
- Schoot, C. Ellen;
- van den Akker, Emile;
- van der Schoot, C Ellen
Publication type:
journal article
Transient receptor potential channel vanilloid type 2 in red cells of cannabis consumer.
Published in:
American Journal of Hematology, 2022, v. 97, n. 5, p. E180, doi. 10.1002/ajh.26509
By:
- Flormann, Daniel;
- Qiao, Min;
- Murciano, Nicoletta;
- Iacono, Giulia;
- Darras, Alexis;
- Hof, Sebastian;
- Recktenwald, Steffen M.;
- Rotordam, Maria Giustina;
- Becker, Nadine;
- Geisel, Jürgen;
- Wagner, Christian;
- von Lindern, Marieke;
- van den Akker, Emile;
- Kaestner, Lars
Publication type:
Article
Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32706-1
By:
- Gallego-Murillo, Joan Sebastián;
- Yağcı, Nurcan;
- Pinho, Eduardo Machado;
- Wahl, Sebastian Aljoscha;
- van den Akker, Emile;
- von Lindern, Marieke
Publication type:
Article
Grsf1-Induced Translation of the SNARE Protein Use1 Is Required for Expansion of the Erythroid Compartment.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0104631
By:
- Nieradka, Andrzej;
- Ufer, Christoph;
- Thiadens, Klaske;
- Grech, Godfrey;
- Horos, Rastislav;
- van Coevorden-Hameete, Marleen;
- van den Akker, Emile;
- Sofi, Sajad;
- Kuhn, Hartmut;
- von Lindern, Marieke
Publication type:
Article
Differential Proteomic Analysis of Human Erythroblasts Undergoing Apoptosis Induced by Epo-Withdrawal.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038356
By:
- Pellegrin, Stéphanie;
- Heesom, Kate J.;
- Satchwell, Timothy J.;
- Hawley, Bethan R.;
- Daniels, Geoff;
- Den Akker, Emile van;
- Toye, Ashley M.
Publication type:
Article