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Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10857-x
By:
- Hiemstra, Steven;
- Fehling-Kaschek, Mirjam;
- Kuijper, Isoude A.;
- Bischoff, Luc J. M.;
- Wijaya, Lukas S.;
- Rosenblatt, Marcus;
- Esselink, Jeroen;
- van Egmond, Allard;
- Mos, Jornt;
- Beltman, Joost B.;
- Timmer, Jens;
- van de Water, Bob;
- Kaschek, Daniel
Publication type:
Article
Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-01863-4
By:
- Koedoot, Esmee;
- van Steijn, Eline;
- Vermeer, Marjolein;
- González-Prieto, Román;
- Vertegaal, Alfred C. O.;
- Martens, John W. M.;
- Le Dévédec, Sylvia E.;
- van de Water, Bob
Publication type:
Article
Imprinted survival genes preclude loss of heterozygosity of chromosome 7 in cancer cells.
Published in:
Journal of Pathology, 2016, v. 240, n. 1, p. 72, doi. 10.1002/path.4756
By:
- Boot, Arnoud;
- Oosting, Jan;
- de Miranda, Noel FCC;
- Zhang, Yinghui;
- Corver, Willem E;
- van de Water, Bob;
- Morreau, Hans;
- van Wezel, Tom
Publication type:
Article
Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.
Published in:
Journal of Pathology, 2015, v. 236, n. 3, p. 348, doi. 10.1002/path.4528
By:
- Baranski, Zuzanna;
- Booij, Tijmen H;
- Cleton‐Jansen, Anne‐Marie;
- Price, Leo S;
- van de Water, Bob;
- Bovée, Judith VMG;
- Hogendoorn, Pancras CW;
- Danen, Erik HJ
Publication type:
Article
Phospho-proteomic analysis of cellular signaling.
Published in:
Electrophoresis, 2006, v. 27, n. 13, p. 2676, doi. 10.1002/elps.200600018
By:
- Marjo de Graauw;
- Paul Hensbergen;
- Bob van de Water
Publication type:
Article
Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia.
Published in:
Breast Cancer Research & Treatment, 2023, v. 198, n. 3, p. 583, doi. 10.1007/s10549-023-06863-w
By:
- Liu, Qiuyu;
- Liu, Nasi;
- van der Noord, Vera;
- van der Stel, Wanda;
- van de Water, Bob;
- Danen, Erik H. J.;
- Le Dévédec, Sylvia E.
Publication type:
Article
Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer.
Published in:
Breast Cancer Research & Treatment, 2019, v. 178, n. 2, p. 263, doi. 10.1007/s10549-019-05380-z
By:
- He, Jichao;
- McLaughlin, Ronan P.;
- van der Noord, Vera;
- Foekens, John A.;
- Martens, John W. M.;
- van Westen, Gerard;
- Zhang, Yinghui;
- van de Water, Bob
Publication type:
Article
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.
Published in:
Archives of Toxicology, 2023, v. 97, n. 2, p. 523, doi. 10.1007/s00204-022-03436-6
By:
- Capinha, Liliana;
- Zhang, Yaran;
- Holzer, Anna-Katharina;
- Ückert, Anna-Katharina;
- Zana, Melinda;
- Carta, Giada;
- Murphy, Cormac;
- Baldovini, Jenna;
- Mazidi, Zahra;
- Grillari, Johannes;
- Dinnyes, Andras;
- van de Water, Bob;
- Leist, Marcel;
- Commandeur, Jan N. M.;
- Jennings, Paul
Publication type:
Article
β<sub>1</sub> Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ--miR-200--ZEB Network in E-Cadherin--Positive Triple-Negative Breast Cancer.
Published in:
Science Signaling, 2014, v. 7, n. 312, p. 1, doi. 10.1126/scisignal.2004751
By:
- Truong, Hoa H.;
- Jiangling Xiong;
- Ghotra, Veerander P. S.;
- Nirmala, Ella;
- Haazen, Lizette;
- Le Dévédec, Sylvia E.;
- Balcioğlu, Hayri E.;
- Shuning He;
- Snaar-Jagalska, B. Ewa;
- Vreugdenhil, Erno;
- Meerman, John H. N.;
- van de Water, Bob;
- Danen, Erik H. J.
Publication type:
Article
Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour.
Published in:
Scientific Reports, 2016, p. 31707, doi. 10.1038/srep31707
By:
- Fokkelman, Michiel;
- Balcıoğlu, Hayri E.;
- Klip, Janna E.;
- Yan, Kuan;
- Verbeek, Fons J.;
- Danen, Erik H. J.;
- van de Water, Bob
Publication type:
Article
Tumor-induced remote ECM network orientation steers angiogenesis.
Published in:
Scientific Reports, 2016, p. 22580, doi. 10.1038/srep22580
By:
- Balcioglu, Hayri E.;
- van de Water, Bob;
- Danen, Erik H. J.
Publication type:
Article
Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.679407
By:
- Yang, Huan;
- van der Stel, Wanda;
- Lee, Randy;
- Bauch, Caroline;
- Bevan, Sam;
- Walker, Paul;
- van de Water, Bob;
- Danen, Erik H. J.;
- Beltman, Joost B.
Publication type:
Article
In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease.
Published in:
Journal of Molecular Cell Biology, 2020, v. 12, n. 8, p. 644, doi. 10.1093/jmcb/mjz029
By:
- Booij, Tijmen H;
- Leonhard, Wouter N;
- Bange, Hester;
- Yan, Kuan;
- Fokkelman, Michiel;
- Plugge, Anna J;
- Veraar, Kimberley A M;
- Dauwerse, Johannes G;
- Westen, Gerard J P van;
- van de Water, Bob;
- Price, Leo S;
- Peters, Dorien J M
Publication type:
Article
Ultra High Content Image Analysis and Phenotype Profiling of 3D Cultured Micro-Tissues.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109688
By:
- Di, Zi;
- Klop, Maarten J. D.;
- Rogkoti, Vasiliki-Maria;
- Le Dévédec, Sylvia E.;
- van de Water, Bob;
- Verbeek, Fons J.;
- Price, Leo S.;
- Meerman, John H. N.
Publication type:
Article
Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076476
By:
- von Stechow, Louise;
- Ruiz-Aracama, Ainhoa;
- van de Water, Bob;
- Peijnenburg, Ad;
- Danen, Erik;
- Lommen, Arjen
Publication type:
Article
Silencing of Doublecortin-Like (DCL) Results in Decreased Mitochondrial Activity and Delayed Neuroblastoma Tumor Growth.
Published in:
PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075752
By:
- Verissimo, Carla S.;
- Elands, Rachel;
- Cheng, Sou;
- Saaltink, Dirk-Jan;
- ter Horst, Judith P.;
- Alme, Maria N.;
- Pont, Chantal;
- van de Water, Bob;
- Håvik, Bjarte;
- Fitzsimons, Carlos P.;
- Vreugdenhil, Erno
Publication type:
Article
Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052337
By:
- Zi Di;
- Herpers, Bram;
- Fredriksson, Lisa;
- Kuan Yan;
- de Water, Bob van;
- Verbeek, Fons J.;
- Meerman, John H. N.
Publication type:
Article
Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031281
By:
- Ghotra, Veerander P. S.;
- Shuning He;
- de Bont, Hans;
- van Der Ent, Wietske;
- Spaink, Herman P.;
- van De Water, Bob;
- naar-Jagalska, B. Ewa;
- Danen, Erik H. J.
Publication type:
Article
Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11020-3
By:
- Koedoot, Esmee;
- Fokkelman, Michiel;
- Rogkoti, Vasiliki-Maria;
- Smid, Marcel;
- van de Sandt, Iris;
- de Bont, Hans;
- Pont, Chantal;
- Klip, Janna E.;
- Wink, Steven;
- Timmermans, Mieke A.;
- Wiemer, Erik A. C.;
- Stoilov, Peter;
- Foekens, John A.;
- Le Dévédec, Sylvia E.;
- Martens, John W. M.;
- van de Water, Bob
Publication type:
Article
Targeting the Heterogeneous Genomic Landscape in Triple-Negative Breast Cancer through Inhibitors of the Transcriptional Machinery.
Published in:
Cancers, 2022, v. 14, n. 18, p. N.PAG, doi. 10.3390/cancers14184353
By:
- van der Noord, Vera E.;
- van de Water, Bob;
- Le Dévédec, Sylvia E.
Publication type:
Article
Utility of Extrapolating Human S1500+ Genes to the Whole Transcriptome: Tunicamycin Case Study.
Published in:
Bioinformatics & Biology Insights, 2020, p. 1, doi. 10.1177/1177932220952742
By:
- Mav, Deepak;
- Phadke, Dhiral P;
- Balik-Meisner, Michele R;
- Merrick, B Alex;
- Auerbach, Scott;
- Niemeijer, Marije;
- Huppelschoten, Suzanna;
- Baze, Audrey;
- Parmentier, Celine;
- Richert, Lysiane;
- van de Water, Bob;
- Shah, Ruchir R;
- Paules, Richard S
Publication type:
Article
Utility of Extrapolating Human S1500+ Genes to the Whole Transcriptome: Tunicamycin Case Study.
Published in:
Bioinformatics & Biology Insights, 2020, p. 1, doi. 10.1177/1177932220952742
By:
- Mav, Deepak;
- Phadke, Dhiral P;
- Balik-Meisner, Michele R;
- Merrick, B Alex;
- Auerbach, Scott;
- Niemeijer, Marije;
- Huppelschoten, Suzanna;
- Baze, Audrey;
- Parmentier, Celine;
- Richert, Lysiane;
- van de Water, Bob;
- Shah, Ruchir R;
- Paules, Richard S
Publication type:
Article
A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy.
Published in:
2019
By:
- McLaughlin, Ronan P.;
- He, Jichao;
- van der Noord, Vera E.;
- Redel, Jevin;
- Foekens, John A.;
- Martens, John W. M.;
- Smid, Marcel;
- Zhang, Yinghui;
- van de Water, Bob
Publication type:
journal article
Insulin-like growth factor 1 receptor activation promotes mammary gland tumor development by increasing glycolysis and promoting biomass production.
Published in:
2017
By:
- Braak, Bas ter;
- Siezen, Christine L.;
- Lee, Joo S.;
- Rao, Pooja;
- Voorhoeve, Charlotte;
- Ruppin, Eytan;
- van der Laan, Jan Willem;
- van de Water, Bob;
- Ter Braak, Bas
Publication type:
journal article
Model-based translation of DNA damage signaling dynamics across cell types.
Published in:
PLoS Computational Biology, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.pcbi.1010264
By:
- Heldring, Muriel M.;
- Wijaya, Lukas S.;
- Niemeijer, Marije;
- Yang, Huan;
- Lakhal, Talel;
- Le Dévédec, Sylvia E.;
- van de Water, Bob;
- Beltman, Joost B.
Publication type:
Article
The integrated stress response‐related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability.
Published in:
Liver International, 2024, v. 44, n. 3, p. 760, doi. 10.1111/liv.15822
By:
- Vlasveld, Matthijs;
- Callegaro, Giulia;
- Fisher, Ciarán;
- Eakins, Julie;
- Walker, Paul;
- Lok, Samantha;
- van Oost, Siddh;
- de Jong, Brechtje;
- Pellegrino‐Coppola, Damiano;
- Burger, Gerhard;
- Wink, Steven;
- van de Water, Bob
Publication type:
Article
An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49809-3
By:
- van der Noord, Vera E.;
- McLaughlin, Ronan P.;
- Smid, Marcel;
- Foekens, John A.;
- Martens, John W. M.;
- Zhang, Yinghui;
- van de Water, Bob
Publication type:
Article
Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47440-w
By:
- Nair, Nishanth Ulhas;
- Das, Avinash;
- Rogkoti, Vasiliki-Maria;
- Fokkelman, Michiel;
- Marcotte, Richard;
- de Jong, Chiaro G.;
- Koedoot, Esmee;
- Lee, Joo Sang;
- Meilijson, Isaac;
- Hannenhalli, Sridhar;
- Neel, Benjamin G.;
- de Water, Bob van;
- Le Dévédec, Sylvia E.;
- Ruppin, Eytan
Publication type:
Article
Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.
Published in:
2019
By:
- Zgheib, Elias;
- Limonciel, Alice;
- Jiang, Xiaoqi;
- Wilmes, Anja;
- Wink, Steven;
- van de Water, Bob;
- Kopp-Schneider, Annette;
- Bois, Frederic Y.;
- Jennings, Paul
Publication type:
Correction Notice
The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells.
Published in:
Oncogene, 1999, v. 18, n. 47, p. 6505, doi. 10.1038/sj.onc.1203060
By:
- Zhan, Yi;
- van de Water, Bob;
- Wang, Yuping;
- Stevens, James L
Publication type:
Article
Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.
Published in:
Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0611-2
By:
- Bronsveld, Heleen K.;
- Braak, Bas ter;
- Karlstad, Øystein;
- Vestergaard, Peter;
- Starup-Linde, Jakob;
- Bazelier, Marloes T.;
- De Bruin, Marie L.;
- de Boer, Anthonius;
- Siezen, Christine L. E.;
- van de Water, Bob;
- van der Laan, Jan Willem;
- Schmidt, Marjanka K.
Publication type:
Article
Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells.
Published in:
Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0600-5
By:
- ter Braak, Bas;
- Wink, Steven;
- Koedoot, Esmee;
- Pont, Chantal;
- Siezen, Christine;
- van der Laan, Jan Willem;
- van de Water, Bob
Publication type:
Article
Mammary gland tumor promotion by chronic administration of IGF1 and the insulin analogue AspB10 in the p53<sup>R270H/+</sup>WAPCre mouse model.
Published in:
Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0518-y
By:
- Braak, Bas ter;
- Siezen, Christine;
- Speksnijder, Ewoud N.;
- Koedoot, Esmee;
- van Steeg, Harry;
- Salvatori, Daniela C. F.;
- de Water, Bob Van;
- der Laan, Jan Willem Van
Publication type:
Article
Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.
Published in:
2015
By:
- Bronsveld, Heleen K;
- Ter Braak, Bas;
- Karlstad, øystein;
- Vestergaard, Peter;
- Starup-Linde, Jakob;
- Bazelier, Marloes T;
- De Bruin, Marie L;
- de Boer, Anthonius;
- Siezen, Christine L E;
- van de Water, Bob;
- van der Laan, Jan Willem;
- Schmidt, Marjanka K;
- Karlstad, Øystein
Publication type:
journal article
Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.
Published in:
Breast Cancer Research, 2011, v. 13, n. 3, p. 1, doi. 10.1186/bcr2883
By:
- Yinghui Zhang;
- Moerkens, Marja;
- Ramaiahgari, Sreenivasa;
- de Bont, Hans;
- Price, Leo;
- Meerman, John;
- van de Water, Bob
Publication type:
Article
Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.
Published in:
Breast Cancer Research, 2011, v. 13, n. 1, p. 1, doi. 10.1186/bcr2883
By:
- Zhang, Yinghui;
- Moerkens, Marja;
- Ramaiahgari, Sreenivasa;
- de Bont, Hans;
- Price, Leo;
- Meerman, John;
- van de Water, Bob
Publication type:
Article
Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes.
Published in:
2011
By:
- Zhang, Yinghui;
- Moerkens, Marja;
- Ramaiahgari, Sreenivasa;
- de Bont, Hans;
- Price, Leo;
- Meerman, John;
- van de Water, Bob
Publication type:
journal article
Mining a human transcriptome database for chemical modulators of NRF2.
Published in:
PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0239367
By:
- Rooney, John P.;
- Chorley, Brian;
- Hiemstra, Steven;
- Wink, Steven;
- Wang, Xuting;
- Bell, Douglas A.;
- van de Water, Bob;
- Corton, J. Christopher
Publication type:
Article
Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase-dependent cell contractility.
Published in:
FASEB Journal, 2009, v. 23, n. 10, p. 3482, doi. 10.1096/fj.08-123398
By:
- Van Miltenburg, Martine H. A. M.;
- Lalai, Reshma;
- De Bont, Hans;
- Van Waaij, Eveline;
- Beggs, Hilary;
- Danen, Erik H. J.;
- Van De Water, Bob
Publication type:
Article
Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1648, doi. 10.1172/JCI74440
By:
- van Roosmalen, Wies;
- Le Dévédec, Sylvia E.;
- Golani, Ofra;
- Smid, Marcel;
- Pulyakhina, Irina;
- Timmermans, Annemieke M.;
- Look, Maxime P.;
- Di Zi;
- Pont, Chantal;
- de Graauw, Marjo;
- Nafar-Abu-Amara, Suha;
- Kirsanova, Catherine;
- Rustici, Gabriella;
- 't Hoen, Peter A. C.;
- Martens, John W. M.;
- Foekens, John A.;
- Geiger, Benjamin;
- van de Water, Bob
Publication type:
Article
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
Published in:
NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0058-z
By:
- Oppelt, Angela;
- Kaschek, Daniel;
- Huppelschoten, Suzanna;
- Sison-Young, Rowena;
- Zhang, Fang;
- Buck-Wiese, Marie;
- Herrmann, Franziska;
- Malkusch, Sebastian;
- Krüger, Carmen L.;
- Meub, Mara;
- Merkt, Benjamin;
- Zimmermann, Lea;
- Schofield, Amy;
- Jones, Robert P.;
- Malik, Hassan;
- Schilling, Marcel;
- Heilemann, Mike;
- van de Water, Bob;
- Goldring, Christopher E.;
- Park, B. Kevin
Publication type:
Article
FAIR High Content Screening in Bioimaging.
Published in:
2023
By:
- Hosseini, Rohola;
- Vlasveld, Matthijs;
- Willemse, Joost;
- van de Water, Bob;
- Le Dévédec, Sylvia E.;
- Wolstencroft, Katherine J.
Publication type:
Product Review
Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors.
Published in:
Environmental Health Perspectives, 2024, v. 132, n. 3, p. 037005-1, doi. 10.1289/EHP11891
By:
- Niemeijer, Marije;
- Więcek, Witold;
- Shuai Fu;
- Huppelschoten, Suzanna;
- Bouwman, Peter;
- Baze, Audrey;
- Parmentier, Céline;
- Richert, Lysiane;
- Paules, Richard S.;
- Bois, Frederic Y.;
- van de Water, Bob
Publication type:
Article
Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice.
Published in:
FASEB Journal, 2006, v. 20, n. 7, p. 953, doi. 10.1096/fj.05-4530fje
By:
- Boesten, Lianne S. M.;
- Zadelaar, A. Susanne M.;
- Van Nieuwkoop, Anita;
- Lihui Hu;
- Jonkers, Jos;
- Van de Water, Bob;
- Gijbels, Marion J. J.;
- Van der Made, Ingeborg;
- De Winther, Menno P. J.;
- Havekes, Louis M.;
- Van Vlijmen, Bart J. M.
Publication type:
Article
Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86664-7
By:
- Koedoot, Esmee;
- Wolters, Liesanne;
- Smid, Marcel;
- Stoilov, Peter;
- Burger, Gerhard A.;
- Herpers, Bram;
- Yan, Kuan;
- Price, Leo S.;
- Martens, John W. M.;
- Le Dévédec, Sylvia E.;
- van de Water, Bob
Publication type:
Article
Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells.
Published in:
Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00388
By:
- Zhang, Yongjie;
- den Braver-Sewradj, Shalenie P.;
- den Braver, Michiel W.;
- Hiemstra, Steven;
- Vermeulen, Nico P. E.;
- van de Water, Bob;
- Commandeur, Jan N. M.;
- Vos, J. C.
Publication type:
Article
Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.
Published in:
Frontiers in Genetics, 2018, p. 1, doi. 10.3389/fgene.2018.00429
By:
- Zgheib, Elias;
- Limonciel, Alice;
- Xiaoqi Jiang;
- Wilmes, Anja;
- Wink, Steven;
- de Water, Bob van;
- Kopp-Schneider, Annette;
- Bois, Frederic Y.;
- Jennings, Paul
Publication type:
Article
Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro.
Published in:
Cell Death & Differentiation, 1998, v. 5, n. 7, p. 601, doi. 10.1038/sj.cdd.4400392
By:
- Kruidering, Maricke;
- van de Water, Bob;
- Zhan, Yi;
- Baelde, Johan J;
- de Heer, Emile;
- Mulder, Gerard J;
- Stevens, Jim L;
- Nagelkerke, JFred
Publication type:
Article
Qualitative and Quantitative Concentration-Response Modelling of Gene Co-expression Networks to Unlock Hepatotoxic Mechanisms for Next Generation Chemical Safety Assessment.
Published in:
Altex, 2024, v. 41, n. 2, p. 213, doi. 10.14573/altex.2309201
By:
- Kunnen, Steven J.;
- Arnesdotter, Emma;
- Willenbockel, Christian Tobias;
- Vinken, Mathieu;
- de Water, Bob van
Publication type:
Article
Protectiveness of NAM-Based Hazard Assessment -- Which Testing Scope is Required?
Published in:
Altex, 2024, v. 41, n. 2, p. 302, doi. 10.14573/altex.2309081
By:
- Zobl, Walter;
- Bitsch, Annette;
- Blum, Jonathan;
- Boei, Jan J. W. A.;
- Capinha, Liliana;
- Carta, Giada;
- Castell, Jose V.;
- Davoli, Enrico;
- Drake, Christina;
- Fisher, Ciaran P.;
- Heldring, Muriel M.;
- Islam, Barira;
- Jennings, Paul;
- Leist, Marcel;
- Pellegrino-Coppola, Damiano;
- Schimming, Johannes P.;
- Snijders, Kirsten E.;
- Tolosa, Laia;
- de Water, Bob van;
- van Vugt-Lussenburg, Barbara M. A.
Publication type:
Article

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