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Optimal experiment design for model selection in biochemical networks.
Published in:
BMC Systems Biology, 2014, v. 8, n. 1, p. 1, doi. 10.1186/1752-0509-8-20
By:
- Vanlier, Joep;
- Tiemann, Christian A.;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
Using Kinetic Modelling to Infer Adaptations in Saccharomyces cerevisiae Carbohydrate Storage Metabolism to Dynamic Substrate Conditions.
Published in:
Metabolites (2218-1989), 2023, v. 13, n. 1, p. 88, doi. 10.3390/metabo13010088
By:
- Lao-Martil, David;
- Verhagen, Koen J. A.;
- Valdeira Caetano, Ana H.;
- Pardijs, Ilse H.;
- van Riel, Natal A. W.;
- Wahl, S. Aljoscha
Publication type:
Article
Kinetic Modeling of Saccharomyces cerevisiae Central Carbon Metabolism: Achievements, Limitations, and Opportunities.
Published in:
Metabolites (2218-1989), 2022, v. 12, n. 1, p. 74, doi. 10.3390/metabo12010074
By:
- Lao-Martil, David;
- Verhagen, Koen J. A.;
- Schmitz, Joep P. J.;
- Teusink, Bas;
- Wahl, S. Aljoscha;
- van Riel, Natal A. W.
Publication type:
Article
Simulating Metabolic Flexibility in Low Energy Expenditure Conditions Using Genome-Scale Metabolic Models.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 10, p. 695, doi. 10.3390/metabo11100695
By:
- Cabbia, Andrea;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
Prognostic Value of Combined Biomarkers in Patients With Heart Failure: The Heartmarker Score.
Published in:
Annals of Laboratory Medicine, 2023, v. 43, n. 3, p. 253, doi. 10.3343/alm.2023.43.3.253
By:
- van der Stam, Jonna A.;
- Bouwmeester, Sjoerd;
- van Loon, Saskia L. M.;
- van Riel, Natal A. W.;
- Dekker, Lukas R.;
- Boer, Arjen-Kars;
- Houthuizen, Patrick;
- Scharnhorst, Volkher
Publication type:
Article
Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data.
Published in:
PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0292030
By:
- O'Donovan, Shauna D.;
- Cavill, Rachel;
- Wimmenauer, Florian;
- Lukas, Alexander;
- Stumm, Tobias;
- Smirnov, Evgueni;
- Lenz, Michael;
- Ertaylan, Gokhan;
- Jennen, Danyel G. J.;
- van Riel, Natal A. W.;
- Driessens, Kurt;
- Peeters, Ralf L. M.;
- de Kok, Theo M. C. M.
Publication type:
Article
Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study.
Published in:
PLoS ONE, 2023, v. 18, n. 7, p. 1, doi. 10.1371/journal.pone.0285820
By:
- Erdős, Balázs;
- van Sloun, Bart;
- Goossens, Gijs H.;
- O'Donovan, Shauna D.;
- de Galan, Bastiaan E.;
- van Greevenbroek, Marleen M. J.;
- Stehouwer, Coen D. A.;
- Schram, Miranda T.;
- Blaak, Ellen E.;
- Adriaens, Michiel E.;
- van Riel, Natal A. W.;
- Arts, Ilja C. W.
Publication type:
Article
Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.
Published in:
Briefings in Bioinformatics, 2006, v. 7, n. 4, p. 364, doi. 10.1093/bib/bbl040
By:
- van Riel, Natal A. W.
Publication type:
Article
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0135665
By:
- Sips, Fianne L. P.;
- Nyman, Elin;
- Adiels, Martin;
- Hilbers, Peter A. J.;
- Strålfors, Peter;
- van Riel, Natal A. W.;
- Cedersund, Gunnar
Publication type:
Article
Prediction of Muscle Energy States at Low Metabolic Rates Requires Feedback Control of Mitochondrial Respiratory Chain Activity by Inorganic Phosphate.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0034118
By:
- Schmitz, Joep P. J.;
- Jeneson, Jeroen A. L.;
- van Oorschot, Joep W. M.;
- Prompers, Jeanine J.;
- Nicolay, Klaas;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
The Accuracy of Wrist-Worn Photoplethysmogram-Measured Heart and Respiratory Rates in Abdominal Surgery Patients: Observational Prospective Clinical Validation Study.
Published in:
JMIR Perioperative Medicine, 2023, v. 6, p. 1, doi. 10.2196/40474
By:
- van der Stam, Jonna A.;
- Mestrom, Eveline H. J.;
- Scheerhoorn, Jai;
- Jacobs, Fleur E. N. B.;
- Nienhuijs, Simon;
- Boer, Arjen-Kars;
- van Riel, Natal A. W.;
- de Morree, Helma M.;
- Bonomi, Alberto G.;
- Scharnhorst, Volkher;
- Bouwman, R. Arthur
Publication type:
Article
Leveraging continuous glucose monitoring for personalized modeling of insulin-regulated glucose metabolism.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-58703-6
By:
- Erdős, Balázs;
- O'Donovan, Shauna D.;
- Adriaens, Michiel E.;
- Gijbels, Anouk;
- Trouwborst, Inez;
- Jardon, Kelly M.;
- Goossens, Gijs H.;
- Afman, Lydia A.;
- Blaak, Ellen E.;
- van Riel, Natal A. W.;
- Arts, Ilja C. W.
Publication type:
Article
Computational modelling of energy balance in individuals with Metabolic Syndrome.
Published in:
BMC Systems Biology, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s12918-019-0705-z
By:
- Rozendaal, Yvonne J. W.;
- Wang, Yanan;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45858-w
By:
- O'Donovan, Shauna D.;
- Lenz, Michael;
- Goossens, Gijs H.;
- van der Kallen, Carla J. H.;
- Eussen, Simone J. M. P.;
- Stehouwer, Coen D. A.;
- van Greevenbroek, Marleen M.;
- Schram, Miranda T.;
- Sep, Simone J.;
- Peeters, Ralf L. M.;
- Blaak, Ellen E.;
- van Riel, Natal A. W.;
- de Kok, Theo M. C. M.;
- Arts, Ilja C. W.
Publication type:
Article
A Dynamic Model for Prediction of Psoriasis Management by Blue Light Irradiation.
Published in:
Frontiers in Physiology, 2017, v. 8, p. 1, doi. 10.3389/fphys.2017.00028
By:
- Garza, Zandra C. Félix;
- Liebmann, Joerg;
- Born, Matthias;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.;
- Schilling, Marcel;
- Tianhui Niu
Publication type:
Article
Use of deep learning methods to translate drug-induced gene expression changes from rat to human primary hepatocytes.
Published in:
PLoS ONE, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pone.0236392
By:
- O'Donovan, Shauna D.;
- Driessens, Kurt;
- Lopatta, Daniel;
- Wimmenauer, Florian;
- Lukas, Alexander;
- Neeven, Jelmer;
- Stumm, Tobias;
- Smirnov, Evgueni;
- Lenz, Michael;
- Ertaylan, Gokhan;
- Jennen, Danyel G. J.;
- van Riel, Natal A. W.;
- Cavill, Rachel;
- Peeters, Ralf L. M.;
- de Kok, Theo M. C. M.
Publication type:
Article
Identifying User Preferences for a Digital Educational Solution for Young Seniors With Diabetes.
Published in:
Diabetes Spectrum, 2017, v. 30, n. 3, p. 182, doi. 10.2337/ds16-0023
By:
- van der Molen, Pieta;
- Maas, Anne H.;
- Wei Chen;
- van Pul, Carola;
- Cottaar, Eduardus J. E.;
- van Riel, Natal A. W.;
- Hilbers, Peter A. J.;
- Haak, Harm R.
Publication type:
Article
Machine Learning for Postoperative Continuous Recovery Scores of Oncology Patients in Perioperative Care with Data from Wearables.
Published in:
Sensors (14248220), 2023, v. 23, n. 9, p. 4455, doi. 10.3390/s23094455
By:
- van den Eijnden, Meike A. C.;
- van der Stam, Jonna A.;
- Bouwman, R. Arthur;
- Mestrom, Eveline H. J.;
- Verhaegh, Wim F. J.;
- van Riel, Natal A. W.;
- Cox, Lieke G. E.
Publication type:
Article
A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation.
Published in:
FASEB Journal, 2015, v. 29, n. 4, p. 1153, doi. 10.1096/fj.14-254656
By:
- Hijmans, Brenda S.;
- Tiemann, Christian A.;
- Grefhorst, Aldo;
- Boesjes, Marije;
- van Dijk, Theo H.;
- Tietge, Uwe J. F.;
- Kuipers, Folkert;
- van Riel, Natal A. W.;
- Groen, Albert K.;
- Oosterveer, Maaike H.
Publication type:
Article
A Computational Model for the Analysis of Lipoprotein Distributions in the Mouse: Translating FPLC Profiles to Lipoprotein Metabolism.
Published in:
PLoS Computational Biology, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.pcbi.1003579
By:
- Sips, Fianne L. P.;
- Tiemann, Christian A.;
- Oosterveer, Maaike H.;
- Groen, Albert K.;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
Parameter Trajectory Analysis to Identify Treatment Effects of Pharmacological Interventions.
Published in:
PLoS Computational Biology, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pcbi.1003166
By:
- Tiemann, Christian A.;
- Vanlier, Joep;
- Oosterveer, Maaike H.;
- Groen, Albert K.;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
Left atrial reservoir strain as a predictor of cardiac outcome in patients with heart failure: the HaFaC cohort study.
Published in:
2022
By:
- Bouwmeester, Sjoerd;
- van der Stam, Jonna A.;
- van Loon, Saskia L. M.;
- van Riel, Natal A. W.;
- Boer, Arjen-Kars;
- Dekker, Lukas R.;
- Scharnhorst, Volkher;
- Houthuizen, Patrick
Publication type:
journal article
Personalized computational model quantifies heterogeneity in postprandial responses to oral glucose challenge.
Published in:
PLoS Computational Biology, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.pcbi.1008852
By:
- Erdős, Balázs;
- van Sloun, Bart;
- Adriaens, Michiel E.;
- O'Donovan, Shauna D.;
- Langin, Dominique;
- Astrup, Arne;
- Blaak, Ellen E.;
- Arts, Ilja C. W.;
- van Riel, Natal A. W.
Publication type:
Article
Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples.
Published in:
BMC Medical Genomics, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s12920-019-0567-7
By:
- Félix Garza, Zandra C.;
- Lenz, Michael;
- Liebmann, Joerg;
- Ertaylan, Gökhan;
- Born, Matthias;
- Arts, Ilja C. W.;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article
Silencing of glycolysis in muscle: experimental observation and numerical analysis.
Published in:
Experimental Physiology, 2010, v. 95, n. 2, p. 380, doi. 10.1113/expphysiol.2009.049841
By:
- Schmitz, Joep P. J.;
- Van Riel, Natal A. W.;
- Nicolay, Klaas;
- Hilbers, Peter A. J.;
- Jeneson, Jeroen A. L.
Publication type:
Article
The influence of temporal resolution in determining pharmacokinetic parameters from DCE-MRI data.
Published in:
Magnetic Resonance in Medicine, 2010, v. 63, n. 3, p. 811, doi. 10.1002/mrm.22171
By:
- Heisen, Marieke;
- Fan, Xiaobing;
- Buurman, Johannes;
- van Riel, Natal A. W.;
- Karczmar, Gregory S.;
- ter Haar Romeny, Bart M.
Publication type:
Article
A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data.
Published in:
PLoS Computational Biology, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pcbi.1007400
By:
- O’Donovan, Shauna D.;
- Lenz, Michael;
- Vink, Roel G.;
- Roumans, Nadia J. T.;
- de Kok, Theo M. C. M.;
- Mariman, Edwin C. M.;
- Peeters, Ralf L. M.;
- van Riel, Natal A. W.;
- van Baak, Marleen A.;
- Arts, Ilja C. W.
Publication type:
Article
Flux Balance Analysis of Plant Metabolism: The Effect of Biomass Composition and Model Structure on Model Predictions.
Published in:
Frontiers in Plant Science, 2016, p. 1, doi. 10.3389/fpls.2016.00537
By:
- Huili Yuan;
- Cheung, C. Y. Maurice;
- Hilbers, Peter A. J.;
- Van Riel, Natal A. W.;
- Seaver, Samuel;
- Misra, Biswapriya Biswavas
Publication type:
Article
A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding.
Published in:
Nutrients, 2022, v. 14, n. 22, p. 4936, doi. 10.3390/nu14224936
By:
- Paalvast, Yared;
- Zhou, Enchen;
- Rozendaal, Yvonne J. W.;
- Wang, Yanan;
- Gerding, Albert;
- van Dijk, Theo H.;
- de Boer, Jan Freark;
- Rensen, Patrick C. N.;
- van Dijk, Ko Willems;
- Kuivenhoven, Jan A.;
- Bakker, Barbara M.;
- van Riel, Natal A. W.;
- Groen, Albert K.
Publication type:
Article
In vivo and in silico dynamics of the development of Metabolic Syndrome.
Published in:
PLoS Computational Biology, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.pcbi.1006145
By:
- Rozendaal, Yvonne J. W.;
- Wang, Yanan;
- Paalvast, Yared;
- Tambyrajah, Lauren L.;
- Li, Zhuang;
- Willems van Dijk, Ko;
- Rensen, Patrick C. N.;
- Kuivenhoven, Jan A.;
- Groen, Albert K.;
- Hilbers, Peter A. J.;
- van Riel, Natal A. W.
Publication type:
Article

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