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Pro-Arrhythmic Potential of Accumulated Uremic Toxins Is Mediated via Vulnerability of Action Potential Repolarization.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5373, doi. 10.3390/ijms24065373
By:
- van Ham, Willem B.;
- Cornelissen, Carlijn M.;
- Polyakova, Elizaveta;
- van der Voorn, Stephanie M.;
- Ligtermoet, Merel L.;
- Monshouwer-Kloots, Jantine;
- Vos, Marc A.;
- Bossu, Alexandre;
- van Rooij, Eva;
- van der Heyden, Marcel A. G.;
- van Veen, Toon A. B.
Publication type:
Article
LUF7244, an allosteric modulator/activator of Kv 11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model.
Published in:
2019
By:
- Qile, Muge;
- Beekman, Henriette D.M.;
- Sprenkeler, David J.;
- Houtman, Marien J.C.;
- Ham, Willem B.;
- Stary‐Weinzinger, Anna;
- Beyl, Stanislav;
- Hering, Steffen;
- Berg, Dirk‐Jan;
- Lange, Elizabeth C.M.;
- Heitman, Laura H.;
- IJzerman, Ad P.;
- Vos, Marc A.;
- Heyden, Marcel A.G.;
- van Ham, Willem B;
- Stary-Weinzinger, Anna;
- van den Berg, Dirk-Jan;
- de Lange, Elizabeth C M;
- van der Heyden, Marcel A G
Publication type:
journal article
Histidine at position 462 determines the low quinine sensitivity of ether-à-go-go channel superfamily member Kv 12.1.
Published in:
2019
By:
- Dierich, Marlen;
- Ham, Willem B.;
- Stary‐Weinzinger, Anna;
- Leitner, Michael G.;
- van Ham, Willem B;
- Stary-Weinzinger, Anna
Publication type:
journal article
Uremic toxins in chronic kidney disease highlight a fundamental gap in understanding their detrimental effects on cardiac electrophysiology and arrhythmogenesis.
Published in:
Acta Physiologica, 2022, v. 236, n. 3, p. 1, doi. 10.1111/apha.13888
By:
- van Ham, Willem B.;
- Cornelissen, Carlijn M.;
- van Veen, Toon A. B.
Publication type:
Article
Quantitative Analysis of the Cytoskeleton's Role in Inward Rectifier K IR 2.1 Forward and Backward Trafficking.
Published in:
Frontiers in Physiology, 2022, v. 12, p. 1, doi. 10.3389/fphys.2021.812572
By:
- Li, Encan;
- Loen, Vera;
- van Ham, Willem B.;
- Kool, Willy;
- van der Heyden, Marcel A. G.;
- Takanari, Hiroki
Publication type:
Article
Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.
Published in:
Science Translational Medicine, 2023, v. 15, n. 688, p. 1, doi. 10.1126/scitranslmed.add4248
By:
- Tsui, Hoyee;
- van Kampen, Sebastiaan Johannes;
- Han, Su Ji;
- Meraviglia, Viviana;
- van Ham, Willem B.;
- Casini, Simona;
- van der Kraak, Petra;
- Vink, Aryan;
- Yin, Xiaoke;
- Mayr, Manuel;
- Bossu, Alexandre;
- Marchal, Gerard A.;
- Monshouwer-Kloots, Jantine;
- Eding, Joep;
- Versteeg, Danielle;
- de Ruiter, Hesther;
- Bezstarosti, Karel;
- Groeneweg, Judith;
- Klaasen, Sjoerd J.;
- van Laake, Linda W.
Publication type:
Article
Maturation and Function of the Intercalated Disc: Report of Two Pediatric Cases Focusing on Cardiac Development and Myocardial Hyperplasia.
Published in:
Journal of Cardiovascular Development & Disease (JCDD), 2023, v. 10, n. 8, p. 354, doi. 10.3390/jcdd10080354
By:
- van Ham, Willem B.;
- Meijboom, Esmeralda E. M.;
- Ligtermoet, Merel L.;
- Nikkels, Peter G. J.;
- van Veen, Toon A. B.
Publication type:
Article

Found: 7

Pro-Arrhythmic Potential of Accumulated Uremic Toxins Is Mediated via Vulnerability of Action Potential Repolarization.

LUF7244, an allosteric modulator/activator of K<sub>v</sub> 11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model.

Histidine at position 462 determines the low quinine sensitivity of ether-à-go-go channel superfamily member K<sub>v</sub> 12.1.

Uremic toxins in chronic kidney disease highlight a fundamental gap in understanding their detrimental effects on cardiac electrophysiology and arrhythmogenesis.

Quantitative Analysis of the Cytoskeleton's Role in Inward Rectifier K<sub> IR </sub>2.1 Forward and Backward Trafficking.

Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.

Maturation and Function of the Intercalated Disc: Report of Two Pediatric Cases Focusing on Cardiac Development and Myocardial Hyperplasia.