Works by van Esdonk, Michiel J.

Results: 25
    1

    Safety, Pharmacokinetics, and Pharmacodynamics of a First‐in‐Class ClC‐1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

    Published in:
    Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 3, p. 768, doi. 10.1002/cpt.3516
    By:
    • Ruijs, Titia Q.;
    • de Cuba, Catherine M. K. E.;
    • Heuberger, Jules A. A. C.;
    • Hutchison, John;
    • Bold, Jane;
    • Grønnebæk, Thomas S.;
    • Jensen, Klaus G.;
    • Chin, Eva;
    • Quiroz, Jorge A.;
    • Petersen, Thomas K.;
    • Flagstad, Peter;
    • de Kam, Marieke L.;
    • van Esdonk, Michiel J.;
    • Klaassen, Erica;
    • Doll, Robert J.;
    • Koopmans, Ingrid W.;
    • de Goede, Annika A.;
    • Aulin, Linda B. S.;
    • Pedersen, Thomas H.;
    • Groeneveld, Geert Jan
    Publication type:
    Article
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    A novel sustained-release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers.

    Published in:
    Pharmacology Research & Perspectives, 2021, v. 9, n. 2, p. 1, doi. 10.1002/prp2.739
    By:
    • Berends, Cécile L.;
    • Pagan, Lisa;
    • van Esdonk, Michiel J.;
    • Klarenbeek, Naomi B.;
    • Bergmann, Kirsten R.;
    • Moerland, Matthijs;
    • der Wel, Vincent van;
    • de Visser, Saco J.;
    • Büller, Hans;
    • Loos, Frans de;
    • de Vries, Wouter S.;
    • Waals, Hans;
    • de Leede, Leo G. J.;
    • Burggraaf, Jacobus;
    • Kamerling, Ingrid M. C.
    Publication type:
    Article
    6

    The power of modelling pulsatile profiles.

    Published in:
    Journal of Pharmacokinetics & Pharmacodynamics, 2021, v. 48, n. 3, p. 439, doi. 10.1007/s10928-021-09743-2
    By:
    • van Esdonk, Michiel J.;
    • Stevens, Jasper
    Publication type:
    Article
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    A phase 1 trial of AP30663, a K<sub>Ca</sub>2 channel inhibitor in development for conversion of atrial fibrillation.

    Published in:
    British Journal of Clinical Pharmacology, 2024, v. 90, n. 4, p. 1027, doi. 10.1111/bcp.15973
    By:
    • Yfanti, Christina;
    • Vestbjerg, Birgitte;
    • van't Westende, Juliette;
    • Edvardsson, Nils;
    • Monfort, Laia Meseguer;
    • Olesen, Morten Salling;
    • Bentzen, Bo Hjorth;
    • Grunnet, Morten;
    • Eveleens Maarse, Boukje C.;
    • Diness, Jonas Goldin;
    • Kemme, Michiel J. B.;
    • Sørensen, Ulrik;
    • Moerland, Matthijs;
    • van Esdonk, Michiel J.;
    • Klaassen, Erica S.;
    • Gal, Pim;
    • Holst, Anders G.
    Publication type:
    Article
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    Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement.

    Published in:
    British Journal of Clinical Pharmacology, 2021, v. 87, n. 12, p. 4658, doi. 10.1111/bcp.14884
    By:
    • Mellion, Michelle L.;
    • Ronco, Lucienne;
    • Berends, Cecile L.;
    • Pagan, Lisa;
    • Brooks, Sander;
    • van Esdonk, Michiel J.;
    • van Brummelen, Emilie M. J.;
    • Odueyungbo, Adefowope;
    • Thompson, Lorin A.;
    • Hage, Michelle;
    • Badrising, Umesh A.;
    • Raines, Shane;
    • Tracewell, William G.;
    • van Engelen, Baziel;
    • Cadavid, Diego;
    • Groeneveld, Geert J.
    Publication type:
    Article
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    Correction: Wind et al. Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial. Cancers 2022, 14 , 1510.

    Published in:
    2023
    By:
    • Wind, Selinde S.;
    • Jansen, Manon A. A.;
    • Rijsbergen, Melanie;
    • van Esdonk, Michiel J.;
    • Ziagkos, Dimitrios;
    • Cheng, Wing C.;
    • Niemeyer-van der Kolk, Tessa;
    • Korsten, John;
    • Gruszka, Agnieszka;
    • Schmitz-Rohmer, Debora;
    • Bonnel, David;
    • Legouffe, Raphael;
    • Barré, Florian;
    • Bekkenk, Marcel W.;
    • de Haas, Ellen R. M.;
    • Quint, Koen D.;
    • Schnidar, Harald;
    • Rolli, Melanie;
    • Streefkerk, Henk Johan;
    • Burggraaf, Jacobus
    Publication type:
    Correction Notice
    18

    Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial.

    Published in:
    Cancers, 2022, v. 14, n. 6, p. 1510, doi. 10.3390/cancers14061510
    By:
    • Wind, Selinde S.;
    • Jansen, Manon A. A.;
    • Rijsbergen, Melanie;
    • van Esdonk, Michiel J.;
    • Ziagkos, Dimitrios;
    • Cheng, Wing C.;
    • Niemeyer-van der Kolk, Tessa;
    • Korsten, John;
    • Gruszka, Agnieszka;
    • Schmitz-Rohmer, Debora;
    • Bonnel, David;
    • Legouffe, Raphael;
    • Barré, Florian;
    • Bekkenk, Marcel W.;
    • de Haas, Ellen R. M.;
    • Quint, Koen D.;
    • Rolli, Melanie;
    • Streefkerk, Henk Johan;
    • Burggraaf, Jacobus;
    • Vermeer, Maarten H.
    Publication type:
    Article
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    A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11014-1
    By:
    • de Valk, Kim S.;
    • Handgraaf, Henricus J.;
    • Deken, Marion M.;
    • Sibinga Mulder, Babs G.;
    • Valentijn, Adrianus R.;
    • Terwisscha van Scheltinga, Anton G.;
    • Kuil, Joeri;
    • van Esdonk, Michiel J.;
    • Vuijk, Jaap;
    • Bevers, Rob F.;
    • Peeters, Koen C.;
    • Holman, Fabian A.;
    • Frangioni, John V.;
    • Burggraaf, Jacobus;
    • Vahrmeijer, Alexander L.
    Publication type:
    Article