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Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease.
Published in:
Nature Medicine, 2003, v. 9, n. 1, p. 40, doi. 10.1038/nm804
By:
- Ghoreschi, Kamran;
- Thomas, Peter;
- Breit, Susanne;
- Dugas, Martin;
- Mailhammer, Reinhard;
- van Eden, Willem;
- van der Zee, Ruurd;
- Biedermann, Tilo;
- Prinz, Jörg;
- Mack, Matthias;
- Mrowietz, Ulrich;
- Christophers, Enno;
- Schlöndorff, Detlef;
- Plewig, Gerd;
- Sander, Christian A.;
- Röcken, Martin
Publication type:
Article
Hsp70 and NF-kB Mediated Control of Innate Inflammatory Responses in a Canine Macrophage Cell Line.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6464, doi. 10.3390/ijms21186464
By:
- Lyu, Qingkang;
- Wawrzyniuk, Magdalena;
- Rutten, Victor P. M. G.;
- van Eden, Willem;
- Sijts, Alice J. A. M.;
- Broere, Femke
Publication type:
Article
Anti-T-Cell Receptor Peptide Specific T-Cells and Adjuvant Arthritis.
Published in:
Annals of the New York Academy of Sciences, 1995, v. 756, n. 1, p. 227, doi. 10.1111/j.1749-6632.1995.tb44519.x
By:
- BROEREN, CHRIS P. M.;
- LUCASSEN, MARJOLEINE A.;
- ZEE, RUURD van der;
- BOOG, CLAIRE J. P.;
- KUSTERS, JOHANNES G.;
- EDEN, WILLEM van
Publication type:
Article
Macrophage Activation Assays to Evaluate the Immunostimulatory Capacity of Avibacterium paragallinarum in A Multivalent Poultry Vaccine.
Published in:
Vaccines, 2020, v. 8, n. 4, p. 671, doi. 10.3390/vaccines8040671
By:
- van den Biggelaar, Robin H. G. A.;
- van Eden, Willem;
- Rutten, Victor P. M. G.;
- Jansen, Christine A.
Publication type:
Article
Nitric Oxide Production and Fc Receptor-Mediated Phagocytosis as Functional Readouts of Macrophage Activity upon Stimulation with Inactivated Poultry Vaccines in Vitro.
Published in:
Vaccines, 2020, v. 8, n. 2, p. 332, doi. 10.3390/vaccines8020332
By:
- van den Biggelaar, Robin H. G. A.;
- van Eden, Willem;
- Rutten, Victor P. M. G.;
- Jansen, Christine A.
Publication type:
Article
Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice.
Published in:
International Immunology, 2012, v. 24, n. 8, p. 507, doi. 10.1093/intimm/dxs057
By:
- Kis-Toth, Katalin;
- Radacs, Marianna;
- Olasz, Katalin;
- van Eden, Willem;
- Mikecz, Katalin;
- Glant, Tibor T.
Publication type:
Article
Nasal application of a naturally processed and presented T cell epitope derived from TCR AV11 protects against adjuvant arthritis.
Published in:
International Immunology, 2000, v. 12, n. 12, p. 1715, doi. 10.1093/intimm/12.12.1715
By:
- van Tienhoven, Esther A. E.;
- Broeren, Chris P. M.;
- Noordzij, Alida;
- Wagenaar, Joseé P. A.;
- van Eden, Willem;
- Wauben, Marca H. M.
Publication type:
Article
A self-hsp60 peptide acts as a partial agonist inducing expression of B7-2 on mycobacterial hsp60-specific T cells: a possible mechanism for inhibitory T cell regulation of adjuvant arthritis?
Published in:
International Immunology, 2000, v. 12, n. 7, p. 1041, doi. 10.1093/intimm/12.7.1041
By:
- Paul, Alberta G. A.;
- van der Zee, Ruurd;
- Taams, Leonie S.;
- van Eden, Willem
Publication type:
Article
Characterization of polarization states of canine monocyte derived macrophages.
Published in:
PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0292757
By:
- Lyu, Qingkang;
- Veldhuizen, Edwin J. A.;
- Ludwig, Irene S.;
- Rutten, Victor P. M. G.;
- van Eden, Willem;
- Sijts, Alice J. A. M.;
- Broere, Femke
Publication type:
Article
Stress, Heat Shock Proteins, and Autoimmunity.
Published in:
Annals of the New York Academy of Sciences, 2007, v. 1113, p. 217, doi. 10.1196/annals.1391.020
By:
- VAN EDEN, WILLEM;
- WICK, GEORGE;
- ALBANI, SALVATORE;
- COHEN, IRUN
Publication type:
Article
Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4+ T cell responses through TLR4 ligation.
Published in:
Scientific Reports, 2016, p. 25064, doi. 10.1038/srep25064
By:
- Brummelman, Jolanda;
- Raeven, René H. M.;
- Helm, Kina;
- Pennings, Jeroen L. A.;
- Metz, Bernard;
- van Eden, Willem;
- van Els, Cécile A. C. M.;
- Han, Wanda G. H.
Publication type:
Article
Heat Shock Proteins Can Be Surrogate Autoantigens for Induction of Antigen Specific Therapeutic Tolerance in Rheumatoid Arthritis.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.00279
By:
- van Eden, Willem;
- Jansen, Manon A. A.;
- Ludwig, Irene S.;
- Leufkens, Paul;
- van der Goes, Marlies C.;
- van Laar, Jacob M.;
- Broere, Femke
Publication type:
Article
<italic>Lactobacillus rhamnosus</italic> GG-Derived Soluble Mediators Modulate Adaptive Immune Cells.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01546
By:
- Ludwig, Irene S.;
- Broere, Femke;
- Manurung, Sarmauli;
- Lambers, Tim T.;
- van der Zee, Ruurd;
- van Eden, Willem
Publication type:
Article
The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01690
By:
- van Eden, Willem;
- Jansen, Manon A. A.;
- de Wolf, A. Charlotte M. T.;
- Ludwig, Irene S.;
- Leufkens, Paul;
- Broere, Femke
Publication type:
Article
The Enigma of Heat Shock Proteins in Immune Tolerance.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01599
By:
- van Eden, Willem;
- Jansen, Manon A. A.;
- Ludwig, Irene;
- van Kooten, Peter;
- van der Zee, Ruurd;
- Broere, Femke
Publication type:
Article
An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01441
By:
- Platteel, Anouk C. M.;
- Liepe, Juliane;
- van Eden, Willem;
- Mishto, Michele;
- Sijts, Alice J. A. M.
Publication type:
Article
T Cell-Mediated Chronic inflammatory Diseases Are Candidates for Therapeutic Tolerance induction with Heat Shock Proteins.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01408
By:
- Betancourt, Ariana Barbera;
- Qingkang Lyu;
- Broere, Femke;
- Sijts, Alice;
- Rutten, Victor P. M. G.;
- van Eden, Willem
Publication type:
Article
In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4+CD25- T Cells Using an Hsp70 Peptide.
Published in:
PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128373
By:
- van Herwijnen, Martijn J. C.;
- van der Zee, Ruurd;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
Activated Peritoneal Cavity B-1a Cells Possess Regulatory B Cell Properties.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088869
By:
- Margry, Bram;
- Kersemakers, Saskia C. W.;
- Hoek, Aad;
- Arkesteijn, Ger J. A.;
- Wieland, Willemien H.;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
Tolerogenic Dendritic Cells That Inhibit Autoimmune Arthritis Can Be Induced by a Combination of Carvacrol and Thermal Stress.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046336
By:
- Spiering, Rachel;
- Van Der Zee, Ruurd;
- Wagenaar, Josée;
- Kapetis, Dimos;
- Zolezzi, Francesca;
- Van Eden, Willem;
- Broere, Femke;
- Song Guo Zheng
Publication type:
Article
PLGA, PLGA-TMC and TMC-TPP Nanoparticles Differentially Modulate the Outcome of Nasal Vaccination by Inducing Tolerance or Enhancing Humoral Immunity.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0026684
By:
- Keijzer, Chantal;
- Slütter, Bram;
- Zee, Ruurd van der;
- Jiskoot, Wim;
- Eden, Willem van;
- Broere, Femke
Publication type:
Article
IL-10 Is Critically Involved in Mycobacterial HSP70 Induced Suppression of Proteoglycan-Induced Arthritis.
Published in:
PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004186
By:
- Wieten, Lotte;
- Berlo, Suzanne E.;
- ten Brink, Corlinda B.;
- van Kooten, Peter J.;
- Singh, Mahavir;
- van der Zee, Ruurd;
- Glant, Tibor T.;
- Broere, Femke;
- van Eden, Willem
Publication type:
Article
Immunomodulatory Effects of Antigen-Pulsed Macrophages in a Murine Model of Allergic Asthma.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2002, v. 27, n. 2, p. 257, doi. 10.1165/ajrcmb.27.2.4788
By:
- Janssen, Edith M.;
- Wauben, Marca H. M.;
- Nijkamp, Frans P.;
- van Eden, Willem;
- van Oosterhout, Antoon J. M.
Publication type:
Article
Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis.
Published in:
Nature, 1988, v. 331, n. 6152, p. 171, doi. 10.1038/331171a0
By:
- Eden, Willem van;
- Tholet, Jelle E. R.;
- Zee, Ruurd van der;
- Noordzij, Alie;
- van Embden, Jan D. A.;
- Hensen, Evert J.;
- Cohen, Irun R.
Publication type:
Article
In vitro Chicken Bone Marrow-Derived Dendritic Cells Comprise Subsets at Different States of Maturation.
Published in:
Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00141
By:
- van den Biggelaar, Robin H. G. A.;
- Arkesteijn, Ger J. A.;
- Rutten, Victor P. M. G.;
- van Eden, Willem;
- Jansen, Christine A.
Publication type:
Article
Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4+ T Cells in a Murine Arthritis Model.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02068
By:
- Jansen, Manon A. A.;
- Spiering, Rachel;
- Ludwig, Irene S.;
- van Eden, Willem;
- Hilkens, Catharien M. U.;
- Broere, Femke
Publication type:
Article
Heat shock proteins are no DAMPs, rather 'DAMPERs'.
Published in:
2011
By:
- Broere, Femke;
- van der Zee, Ruurd;
- van Eden, Willem
Publication type:
commentary
Heat-shock proteins induce T-cell regulation of chronic inflammation.
Published in:
Nature Reviews Immunology, 2005, v. 5, n. 4, p. 318, doi. 10.1038/nri1593
By:
- Van Eden, Willem;
- Van der Zee, Ruurd;
- Prakken, Berent
Publication type:
Article
Transcriptome Analysis of The Inflammatory Responses of Bovine Mammary Epithelial Cells: Exploring Immunomodulatory Target Genes for Bovine Mastitis.
Published in:
Pathogens, 2020, v. 9, n. 3, p. 200, doi. 10.3390/pathogens9030200
By:
- Islam, Md. Aminul;
- Takagi, Michihiro;
- Fukuyama, Kohtaro;
- Komatsu, Ryoya;
- Albarracin, Leonardo;
- Nochi, Tomonori;
- Suda, Yoshihito;
- Ikeda-Ohtsubo, Wakako;
- Rutten, Victor;
- Eden, Willem van;
- Villena, Julio;
- Aso, Hisashi;
- Kitazawa, Haruki
Publication type:
Article
Heat shock proteins and their immunomodulatory role in inflammatory arthritis.
Published in:
Rheumatology, 2017, v. 56, n. 2, p. 198, doi. 10.1093/rheumatology/kew266
By:
- Spierings, Julia;
- van Eden, Willem
Publication type:
Article
Proteomic analysis of chicken bone marrow-derived dendritic cells in response to an inactivated IBV + NDV poultry vaccine.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89810-3
By:
- van den Biggelaar, Robin H. G. A.;
- van der Maas, Larissa;
- Meiring, Hugo D.;
- Pennings, Jeroen L. A.;
- van Eden, Willem;
- Rutten, Victor P. M. G.;
- Jansen, Christine A.
Publication type:
Article
An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 3, p. 639, doi. 10.1002/art.39444
By:
- de Wolf, Charlotte;
- van der Zee, Ruurd;
- den Braber, Ineke;
- Glant, Tibor;
- Maillère, Bernard;
- Favry, Emmanuel;
- van Lummel, Menno;
- Koning, Frits;
- Hoek, Aad;
- Ludwig, Irene;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity.
Published in:
Scientific Reports, 2013, p. 1, doi. 10.1038/srep02478
By:
- Jansen, Christine A.;
- de Geus, Eveline;
- van Haarlem, Daphne A.;
- van de Haar, Peter M.;
- Löndt, Brandon Z.;
- Graham, Simon P.;
- Göbel, Thomas W.;
- van Eden, Willem;
- Brookes, Sharon M.;
- Vervelde, Lonneke
Publication type:
Article
Stress proteins are used by the immune system for cognate interactions with anti-inflammatory regulatory T cells.
Published in:
FEBS Letters, 2013, v. 587, n. 13, p. 1951, doi. 10.1016/j.febslet.2013.05.024
By:
- van Eden, Willem;
- van Herwijnen, Martijn;
- Wagenaar, Josée;
- van Kooten, Peter;
- Broere, Femke;
- van der Zee, Ruurd
Publication type:
Article
Targeting of tolerogenic dendritic cells towards heat-shock proteins: a novel therapeutic strategy for autoimmune diseases?
Published in:
Immunology, 2018, v. 153, n. 1, p. 51, doi. 10.1111/imm.12811
By:
- Jansen, Manon A. A.;
- Spiering, Rachel;
- Broere, Femke;
- van Laar, Jacob M.;
- Isaacs, John D.;
- van Eden, Willem;
- Hilkens, Catharien M. U.
Publication type:
Article
Presentation of the candidate rheumatoid arthritis autoantigen aggrecan by antigen-specific B cells induces enhanced CD4+ T helper type 1 subset differentiation.
Published in:
Immunology, 2012, v. 135, n. 4, p. 344, doi. 10.1111/j.1365-2567.2011.03548.x
By:
- Wilson, Caroline L.;
- Hine, Dominic W.;
- Pradipta, Ariel;
- Pearson, Jeffrey P.;
- van Eden, Willem;
- Robinson, John H.;
- Knight, Andrew M.
Publication type:
Article
HLA-linked control of predisposition to lepromatous leprosy.
Published in:
1985
By:
- van Eden, Willem;
- Gonzalez, Nieves M.;
- de Vries, Rene R. P.;
- Convit, Jacinto;
- van Rood, Jon J.;
- van Eden, W;
- Gonzalez, N M;
- de Vries, R R;
- Convit, J;
- van Rood, J J
Publication type:
journal article
First International Conference on the Pathogenesis of Mycobacterial Infections: A Summary.
Published in:
Clinical Infectious Diseases, 1992, v. 14, n. 1, p. 308
By:
- Rastogi, Nalin;
- McFadden, Johnjoe;
- Ottenhoff, Tom H. M.;
- Eden, Willem van
Publication type:
Article
Cell stress induced HSP are targets of regulatory T cells: A role for HSP inducing compounds as anti-inflammatory immuno-modulators?
Published in:
FEBS Letters, 2007, v. 581, n. 19, p. 3716, doi. 10.1016/j.febslet.2007.04.082
By:
- Wieten, Lotte;
- Broere, Femke;
- van der Zee, Ruurd;
- Koerkamp, Elles Klein;
- Wagenaar, Josée;
- van Eden, Willem
Publication type:
Article
Membrane-Bound Metallothionein 1 of Murine Dendritic Cells Promotes the Expansion of Regulatory T Cells In Vitro.
Published in:
Toxicological Sciences, 2014, v. 138, n. 1, p. 69, doi. 10.1093/toxsci/kft268
By:
- Spiering, Rachel;
- Wagenaar-Hilbers, Josée;
- Huijgen, Veerle;
- van der Zee, Ruurd;
- van Kooten, Peter J. S.;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
Extracellular HSPs: The Complicated Roles of Extracellular HSPs in Immunity.
Published in:
Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00159
By:
- Calderwood, Stuart K.;
- Gong, Jianlin;
- Murshid, Ayesha;
- Van Eden, Willem;
- Fournel, Sylvie;
- Wheeler, Robert T.;
- Xiang-Yang Wang
Publication type:
Article
Generation of the First TCR Transgenic Mouse with CD4+ T Cells Recognizing an Anti-inflammatory Regulatory T Cell-Inducing Hsp70 Peptide.
Published in:
Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00090
By:
- Jansen, Manon A. A.;
- van Herwijnen, Martijn J. C.;
- van Kooten, Peter J. S.;
- Hoek, Aad;
- van der Zee, Ruurd;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
1,25-Dihydroxyvitamin D3-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease.
Published in:
Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00575
By:
- Besusso, Dario;
- Saul, Louise;
- Leech, Melanie D.;
- O'Connor, Richard A.;
- MacDonald, Andrew S.;
- Anderton, Stephen M.;
- Mellanby, Richard J.;
- Masaaki Murakami;
- Van Eden, Willem
Publication type:
Article
Treg inducing adjuvants for therapeutic vaccination against chronic inflammatory diseases.
Published in:
Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00245
By:
- Keijzer, Chantal;
- van der Zee, Ruurd;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
The immunology of cellular stress proteins.
Published in:
Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00153
By:
- Van Eden, Willem;
- Bonorino, Cristina;
- Van Der Zee, Ruurd
Publication type:
Article
Opposing roles for heat and heat shock proteins in macrophage functions during inflammation: a function of cell activation state?
Published in:
Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00140
By:
- Chen-Ting Lee;
- Repasky, Elizabeth A.;
- van Eden, Willem;
- i Giovine, Francesco Saverio;
- Yoshida, Hiroki
Publication type:
Article
The tricky balancing act of using heat shock proteins for cross-presentation.
Published in:
2012
By:
- Sijts, Alice J.;
- van Eden, Willem
Publication type:
Opinion
The anti-inflammatory mechanisms of Hsp70.
Published in:
Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00095
By:
- Borges, Thiago J.;
- Wieten, Lotte;
- van Herwijnen, Martijn J. C.;
- Broere, Femke;
- van der Zee, Ruurd;
- Bonorino, Cristina;
- van Eden, Willem
Publication type:
Article
Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection.
Published in:
European Journal of Immunology, 2009, v. 39, n. 11, p. 3031, doi. 10.1002/eji.200939619
By:
- Van Rhijn, Ildiko;
- Nguyen, Thi Kim Anh;
- Michel, Anita;
- Cooper, Dave;
- Govaerts, Marc;
- Cheng, Tan-Yun;
- van Eden, Willem;
- Moody, D. Branch;
- Coetzer, Jacobus A. W.;
- Rutten, Victor;
- Koets, Ad P.
Publication type:
Article
Translating immunological tolerance into therapy.
Published in:
European Journal of Immunology, 2007, v. 37, n. 9, p. 2360, doi. 10.1002/eji.200790036
By:
- Prakken, Berent J.;
- Albani, Salvatore;
- van Eden, Willem
Publication type:
Article

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