Works matching AU van Brummelen, Emilie M. J.

Results: 11

BRAF Mutations as Predictive Biomarker for Response to Anti-EGFR Monoclonal Antibodies.

Published in:

Oncologist, 2017, v. 22, n. 7, p. 864, doi. 10.1634/theoncologist.2017-0031

By:

van Brummelen, Emilie M. J.;
de Boer, Anthonius;
Beijnen, Jos H.;
Schellens, Jan H. M.

Publication type:

Article

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.

Published in:

2020

By:

van Geel, Robin M. J. M.;
van Brummelen, Emilie M. J.;
Eskens, Ferry A. L. M.;
Huijberts, Sanne C. F. A.;
de Vos, Filip Y. F. L.;
Lolkema, Martijn P. J. K.;
Devriese, Lot A.;
Opdam, Frans L.;
Marchetti, Serena;
Steeghs, Neeltje;
Monkhorst, Kim;
Thijssen, Bas;
Rosing, Hilde;
Huitema, Alwin D. R.;
Beijnen, Jos H.;
Bernards, René;
Schellens, Jan H. M.

Publication type:

journal article

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

Published in:

2020

By:

Huijberts, Sanne C. F. A.;
van Geel, Robin M. J. M.;
van Brummelen, Emilie M. J.;
Opdam, Frans L.;
Marchetti, Serena;
Steeghs, Neeltje;
Pulleman, Saskia;
Thijssen, Bas;
Rosing, Hilde;
Monkhorst, Kim;
Huitema, Alwin D. R.;
Beijnen, Jos H.;
Bernards, René;
Schellens, Jan H. M.

Publication type:

journal article

Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season.

Published in:

Human Vaccines & Immunotherapeutics, 2020, v. 16, n. 6, p. 1322, doi. 10.1080/21645515.2019.1688040

By:

Van Der Plas, Johan L.;
Verdijk, Pauline;
Van Brummelen, Emilie M. J.;
Jeeninga, Rienk E.;
Roestenberg, Meta;
Burggraaf, Jacobus;
Kamerling, Ingrid M.C.

Publication type:

Article

Healthy volunteers in first‐in‐human oncology drug development for small molecules.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 4, p. 1773, doi. 10.1111/bcp.15092

By:

de las Heras, Begoña;
Bouyoucef‐Cherchalli, Dalila;
Reeve, Lesley;
Reichl, Andreas;
Mandarino, Debra;
Flach, Stephen;
Vidal, Laura;
van Brummelen, Emilie M. J.;
Steeghs, Neeltje

Publication type:

Article

First‐in‐human trial to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of STR‐324, a dual enkephalinase inhibitor for pain management.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 103, doi. 10.1111/bcp.14931

By:

Moss, Laurence M.;
Berends, Cecile L.;
van Brummelen, Emilie M. J.;
Kamerling, Ingrid M. C.;
Klaassen, Erica S.;
Bergmann, Kirsten;
Ville, Vanessa;
Juarez‐Perez, Victor;
Benichou, Annie‐Claude;
Groeneveld, Geert Jan

Publication type:

Article

Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement.

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 12, p. 4658, doi. 10.1111/bcp.14884

By:

Mellion, Michelle L.;
Ronco, Lucienne;
Berends, Cecile L.;
Pagan, Lisa;
Brooks, Sander;
van Esdonk, Michiel J.;
van Brummelen, Emilie M. J.;
Odueyungbo, Adefowope;
Thompson, Lorin A.;
Hage, Michelle;
Badrising, Umesh A.;
Raines, Shane;
Tracewell, William G.;
van Engelen, Baziel;
Cadavid, Diego;
Groeneveld, Geert J.

Publication type:

Article

A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma.

Published in:

Investigational New Drugs, 2020, v. 38, n. 2, p. 457, doi. 10.1007/s10637-019-00783-7

By:

van Brummelen, Emilie M. J.;
Levchenko, Evgeny;
Dómine, Manuel;
Fennell, Dean A.;
Kindler, Hedy L.;
Viteri, Santiago;
Gadgeel, Shirish;
López, Pilar Garrido;
Kostorov, Vladimir;
Morgensztern, Daniel;
Orlov, Sergey;
Zauderer, Marjorie G.;
Vansteenkiste, Johan F.;
Baker-Neblett, Katherine;
Vasquez, James;
Wang, Xiaowei;
Bellovin, David I.;
Schellens, Jan H. M.;
Yan, Li;
Mitrica, Ionel

Publication type:

Article

Integration of healthy volunteers in early phase clinical trials with immunooncological compounds.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.954806

By:

Radanovic, Igor;
Klarenbeek, Naomi;
Rissmann, Robert;
Groeneveld, Geert Jan;
van Brummelen, Emilie M. J.;
Moerland, Matthijs;
Bosch, Jacobus J.

Publication type:

Article

A phase I, randomized, double‐blind, placebo‐controlled, single‐ and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX‐128, a highly selective Na<sub>v</sub>1.8 inhibitor, in healthy adults

Published in:

CTS: Clinical & Translational Science, 2022, v. 15, n. 4, p. 981, doi. 10.1111/cts.13215

By:

Hijma, Hemme J.;
van Brummelen, Emilie M. J.;
Siebenga, Pieter S.;
Groeneveld, Geert Jan

Publication type:

Article

Touchscreen-based finger tapping: Repeatability and configuration effects on tapping performance.

Published in:

PLoS ONE, 2021, v. 16, n. 12, p. 1, doi. 10.1371/journal.pone.0260783

By:

Makai-Bölöni, Soma;
Thijssen, Eva;
van Brummelen, Emilie M. J.;
Groeneveld, Geert J.;
Doll, Robert J.

Publication type:

Article