Works by van Attikum, Haico

Results: 42

Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56561-y

By:

van der Horst, Sophie C.;
Kollenstart, Leonie;
Batté, Amandine;
Keizer, Sander;
Vreeken, Kees;
Pandey, Praveen;
Chabes, Andrei;
van Attikum, Haico

Publication type:

Article

The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51090-6

By:

van de Kooij, Bert;
van der Wal, Fenna J.;
Rother, Magdalena B.;
Wiegant, Wouter W.;
Creixell, Pau;
Stout, Merula;
Joughin, Brian A.;
Vornberger, Julia;
Altmeyer, Matthias;
van Vugt, Marcel A. T. M.;
Yaffe, Michael B.;
van Attikum, Haico

Publication type:

Article

The small CRL4<sup>CSA</sup> ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50584-7

By:

Llerena Schiffmacher, Diana A.;
Lee, Shun-Hsiao;
Kliza, Katarzyna W.;
Theil, Arjan F.;
Akita, Masaki;
Helfricht, Angela;
Bezstarosti, Karel;
Gonzalo-Hansen, Camila;
van Attikum, Haico;
Verlaan-de Vries, Matty;
Vertegaal, Alfred C. O.;
Hoeijmakers, Jan H. J.;
Marteijn, Jurgen A.;
Lans, Hannes;
Demmers, Jeroen A. A.;
Vermeulen, Michiel;
Sixma, Titia K.;
Ogi, Tomoo;
Vermeulen, Wim;
Pines, Alex

Publication type:

Article

Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining.

Published in:

Cell Cycle, 2013, v. 12, n. 18, p. 3070, doi. 10.4161/cc.26033

By:

Helfricht, Angela;
Wiegant, Wouter W.;
Thijssen, Peter E.;
Vertegaal, Alfred C.;
Luijsterbur, Martijn S.;
van Attikum, Haico

Publication type:

Article

Chromatin and the DNA damage response: The cancer connection

Published in:

Molecular Oncology, 2011, v. 5, n. 4, p. 349, doi. 10.1016/j.molonc.2011.06.001

By:

Luijsterburg, Martijn S.;
van Attikum, Haico

Publication type:

Article

Chl1 helicase controls replication fork progression by regulating dNTP pools.

Published in:

Life Science Alliance, 2022, v. 5, n. 4, p. 1, doi. 10.26508/lsa.202101153

By:

Batté, Amandine;
van der Horst, Sophie C.;
Tittel-Elmer, Mireille;
Su Ming Sun;
Sushma Sharma;
van Leeuwen, Jolanda;
Chabes, Andrei;
van Attikum, Haico

Publication type:

Article

The Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T‐DNA.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 14, p. 4247, doi. 10.1093/nar/gkg458

By:

van Attikum, Haico;
Bundock, Paul;
Overmeer, René M.;
Lee, Lan‐Ying;
Gelvin, Stanton B.;
Hooykaas, Paul J. J.

Publication type:

Article

Genetic requirements for the targeted integration of Agrobacterium T‐DNA in Saccharomyces cerevisiae.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 3, p. 826, doi. 10.1093/nar/gkg183

By:

van Attikum, Haico;
Hooykaas, Paul J. J.

Publication type:

Article

Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 15, p. 3395, doi. 10.1093/nar/gkf445

By:

Bundock, Paul;
van Attikum, Haico;
Hooykaas, Paul

Publication type:

Article

Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26691-0

By:

Singh, Jenny Kaur;
Smith, Rebecca;
Rother, Magdalena B.;
de Groot, Anton J. L.;
Wiegant, Wouter W.;
Vreeken, Kees;
D'Augustin, Ostiane;
Kim, Robbert Q.;
Qian, Haibin;
Krawczyk, Przemek M.;
González-Prieto, Román;
Vertegaal, Alfred C. O.;
Lamers, Meindert;
Huet, Sébastien;
van Attikum, Haico

Publication type:

Article

Insertional mutagenesis in yeasts using T-DNA from Agrobacterium tumefaciens.

Published in:

Yeast, 2002, v. 19, n. 6, p. 529, doi. 10.1002/yea.858

By:

Bundock, Paul;
van Attikum, Haico;
den Dulk-Ras, Amke;
Hooykaas, Paul J. J.

Publication type:

Article

Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes.

Published in:

PLoS Genetics, 2009, v. 5, n. 12, p. 1, doi. 10.1371/journal.pgen.1000782

By:

Hannum, Gregory;
Srivas, Rohith;
Guénolé, Aude;
van Attikum, Haico;
Krogan, Nevan J.;
Karp, Richard M.;
Ideker, Trey

Publication type:

Article

The histone code at DNA breaks: a guide to repair?

Published in:

Nature Reviews Molecular Cell Biology, 2005, v. 6, n. 10, p. 757, doi. 10.1038/nrm1737

By:

Van Attikum, Haico;
Gasser, Susan M.

Publication type:

Article

Chromatin at the crossroads. Meeting on Signalling to Chromatin Epigenetics.

Published in:

EMBO Reports, 2006, v. 7, n. 12, p. 1206, doi. 10.1038/sj.embor.7400834

By:

West, Adam G;
van Attikum, Haico

Publication type:

Article

Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2021.809832

By:

van de Kooij, Bert;
van Attikum, Haico

Publication type:

Article

Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2021.809832

By:

van de Kooij, Bert;
van Attikum, Haico

Publication type:

Article

Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32743-w

By:

van de Kooij, Bert;
Kruswick, Alex;
van Attikum, Haico;
Yaffe, Michael B.

Publication type:

Article

ATP-Dependent Chromatin Remodeling and DNA Double-Strand Break Repair.

Published in:

Cell Cycle, 2005, v. 4, n. 8, p. 1011, doi. 10.4161/cc.4.8.1887

By:

van Attikum, Haico;
Gasser, Susan M.

Publication type:

Article

Improved functional overview of protein complexes using inferred epistatic relationships.

Published in:

BMC Systems Biology, 2011, v. 5, n. 1, p. 80, doi. 10.1186/1752-0509-5-80

By:

Ryan, Colm;
Greene, Derek;
Guénolé, Aude;
Attikum, Haico van;
Krogan, Nevan J;
Cunningham, Pádraig;
Cagney, Gerard

Publication type:

Article

Regulation of Nuclear Positioning and Dynamics of the Silent Mating Type Loci by the Yeast Ku70/Ku80 Complex.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 3, p. 835, doi. 10.1128/MCB.01009-08

By:

Bystricky, Kerstin;
van Attikum, Haico;
Montiel, Maria-Dolores;
Dion, Vincent;
Gehlen, Lutz;
Gasser, Susan M.

Publication type:

Article

Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair.

Published in:

Journal of Cell Biology, 2014, v. 207, n. 6, p. 717, doi. 10.1083/jcb.201405077

By:

Klement, Karolin;
Luijsterburg, Martijn S.;
Pinder, Jordan B.;
Cena, Chad S.;
Del Nero, Victor;
Wintersinger, Christopher M.;
Dellaire, Graham;
van Attikum, Haico;
Goodarzi, Aaron A.

Publication type:

Article

DDB2 promotes chromatin decondensation at UV-induced DNA damage.

Published in:

Journal of Cell Biology, 2012, v. 197, n. 2, p. 267, doi. 10.1083/jcb.201106074

By:

Luijsterburg, Martijn S.;
Lindh, Michael;
Acs, Klara;
Vrouwe, Mischa G.;
Pines, Alex;
van Attikum, Haico;
Mullenders, Leon H.;
Dantuma, Nico P.

Publication type:

Article

The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage.

Published in:

Journal of Cell Biology, 2010, v. 190, n. 5, p. 741, doi. 10.1083/jcb.201001048

By:

Smeenk, Godelieve;
Wiegant, Wouter W.;
Vrolijk, Hans;
Solari, Aldo P.;
Pastink, Albert;
Attikum, Haico van

Publication type:

Article

Meta-analysis of DNA double-strand break response kinetics.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 22, p. 12625, doi. 10.1093/nar/gkx1128

By:

Kochan, Jakub A.;
Desclos, Emilie C.B.;
Bosch, Ruben;
Meister, Luna;
Vriend, Lianne E.M.;
van Attikum, Haico;
Krawczyk, Przemek M.

Publication type:

Article

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 14, p. 6919, doi. 10.1093/nar/gkv613

By:

Typas, Dimitris;
Luijsterburg, Martijn S.;
Wiegant, Wouter W.;
Diakatou, Michaela;
Helfricht, Angela;
Thijssen, Peter E.;
van de Broek, Bram;
Mullenders, Leon H.;
van Attikum, Haico

Publication type:

Article

Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 13, p. 8473, doi. 10.1093/nar/gku565

By:

Aydin, Özge Z.;
Marteijn, Jurgen A.;
Ribeiro-Silva, Cristina;
Rodríguez López, Aida;
Wijgers, Nils;
Smeenk, Godelieve;
van Attikum, Haico;
Poot, Raymond A.;
Vermeulen, Wim;
Lans, Hannes

Publication type:

Article

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04649-z

By:

Velimezi, Georgia;
Robinson-Garcia, Lydia;
Muñoz-Martínez, Francisco;
Wiegant, Wouter W.;
da Silva, Joana Ferreira;
Owusu, Michel;
Moder, Martin;
Wiedner, Marc;
Rosenthal, Sara Brin;
Fisch, Kathleen M.;
Moffat, Jason;
Menche, Jörg;
van Attikum, Haico;
Jackson, Stephen P.;
Loizou, Joanna I.

Publication type:

Article

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03484-6

By:

Pines, Alex;
Dijk, Madelon;
Makowski, Matthew;
Meulenbroek, Elisabeth M.;
Vrouwe, Mischa G.;
van der Weegen, Yana;
Baltissen, Marijke;
French, Pim J.;
van Royen, Martin E.;
Luijsterburg, Martijn S.;
Mullenders, Leon H.;
Vermeulen, Michiel;
Vermeulen, Wim;
Pannu, Navraj S.;
van Attikum, Haico

Publication type:

Article

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.

Published in:

EMBO Journal, 2012, v. 31, n. 18, p. 3768, doi. 10.1038/emboj.2012.195

By:

Hegnauer, Anna Maria;
Hustedt, Nicole;
Shimada, Kenji;
Pike, Brietta L;
Vogel, Markus;
Amsler, Philipp;
Rubin, Seth M;
van Leeuwen, Fred;
Guénolé, Aude;
van Attikum, Haico;
Thomä, Nicolas H;
Gasser, Susan M

Publication type:

Article

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure.

Published in:

EMBO Journal, 2012, v. 31, n. 11, p. 2511, doi. 10.1038/emboj.2012.104

By:

Luijsterburg, Martijn S;
Acs, Klara;
Ackermann, Leena;
Wiegant, Wouter W;
Bekker-Jensen, Simon;
Larsen, Dorthe H;
Khanna, Kum Kum;
van Attikum, Haico;
Mailand, Niels;
Dantuma, Nico P

Publication type:

Article

Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks.

Published in:

EMBO Journal, 2007, v. 26, n. 18, p. 4113, doi. 10.1038/sj.emboj.7601835

By:

van Attikum, Haico;
Fritsch, Olivier;
Gasser, Susan M.

Publication type:

Article

Non-homologous end-joining proteins are required for Agrobacterium T-DNA integration.

Published in:

EMBO Journal, 2001, v. 20, n. 22, p. 6550, doi. 10.1093/emboj/20.22.6550

By:

van Attikum, Haico;
Bundock, Paul;
Hooykaas, Paul J.J.

Publication type:

Article

Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91359-0

By:

Kollenstart, Leonie;
van der Horst, Sophie C.;
Vreeken, Kees;
Janssen, George M. C.;
Martino, Fabrizio;
Vlaming, Hanneke;
van Veelen, Peter A.;
van Leeuwen, Fred;
van Attikum, Haico

Publication type:

Article

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19502-5

By:

Rother, Magdalena B.;
Pellegrino, Stefania;
Smith, Rebecca;
Gatti, Marco;
Meisenberg, Cornelia;
Wiegant, Wouter W.;
Luijsterburg, Martijn S.;
Imhof, Ralph;
Downs, Jessica A.;
Vertegaal, Alfred C. O.;
Huet, Sébastien;
Altmeyer, Matthias;
van Attikum, Haico

Publication type:

Article

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.

Published in:

Nature, 2012, v. 489, n. 7417, p. 581, doi. 10.1038/nature11353

By:

Costelloe, Thomas;
Louge, Raphaël;
Tomimatsu, Nozomi;
Mukherjee, Bipasha;
Martini, Emmanuelle;
Khadaroo, Basheer;
Dubois, Kenny;
Wiegant, Wouter W.;
Thierry, Agnès;
Burma, Sandeep;
van Attikum, Haico;
Llorente, Bertrand

Publication type:

Article

A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.20922

By:

Luijsterburg, Martijn S.;
Typas, Dimitris;
Caron, Marie-Christine;
Wiegant, Wouter W.;
van den Heuvel, Diana;
Boonen, Rick A.;
Couturier, Anthony M.;
Mullenders, Leon H.;
Masson, Jean-Yves;
van Attikum, Haico

Publication type:

Article

Proteomic analysis identifies novel binding partners of BAP1.

Published in:

PLoS ONE, 2021, v. 16, n. 9, p. 1, doi. 10.1371/journal.pone.0257688

By:

Baas, Roy;
J. van der Wal, Fenna;
Bleijerveld, Onno B.;
van Attikum, Haico;
Sixma, Titia K.

Publication type:

Article

PHF6 promotes non‐homologous end joining and G2 checkpoint recovery.

Published in:

EMBO Reports, 2020, v. 21, n. 1, p. N.PAG, doi. 10.15252/embr.201948460

By:

Warmerdam, Daniël O;
Alonso‐de Vega, Ignacio;
Wiegant, Wouter W;
van den Broek, Bram;
Rother, Magdalena B;
Wolthuis, Rob MF;
Freire, Raimundo;
van Attikum, Haico;
Medema, René H;
Smits, Veronique AJ

Publication type:

Article

Antisense oligonucleotide-mediated exon skipping as a strategy to reduce proteolytic cleavage of ataxin-3.

Published in:

Scientific Reports, 2016, p. 35200, doi. 10.1038/srep35200

By:

Toonen, Lodewijk J. A.;
Schmidt, Iris;
Luijsterburg, Martijn S.;
van Attikum, Haico;
van Roon-Mom, Willeke M. C.

Publication type:

Article

Functional analysis of genetic variants in the high-risk breast cancer susceptibility gene PALB2.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13194-2

By:

Boonen, Rick A. C. M.;
Rodrigue, Amélie;
Stoepker, Chantal;
Wiegant, Wouter W.;
Vroling, Bas;
Sharma, Milan;
Rother, Magdalena B.;
Celosse, Nandi;
Vreeswijk, Maaike P. G.;
Couch, Fergus;
Simard, Jacques;
Devilee, Peter;
Masson, Jean-Yves;
van Attikum, Haico

Publication type:

Article

The CHD6 chromatin remodeler is an oxidative DNA damage response factor.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08111-y

By:

Moore, Shaun;
Berger, N. Daniel;
Luijsterburg, Martijn S.;
Piett, Cortt G.;
Stanley, Fintan K. T.;
Schräder, Christoph U.;
Fang, Shujuan;
Chan, Jennifer A.;
Schriemer, David C.;
Nagel, Zachary D.;
van Attikum, Haico;
Goodarzi, Aaron A.

Publication type:

Article

SWI/SNF complex in disorder SWItching from malignancies to intellectual disability.

Published in:

Epigenetics, 2012, v. 7, n. 11, p. 1219, doi. 10.4161/epi.22299

By:

Santen, Gijs W. E.;
Kriek, Marjolein;
van Attikum, Haico

Publication type:

Article