Works by dos Santos, Helcio Silva

Results: 73

Antibacterial potential of chalcones and its derivatives against Staphylococcus aureus.

Published in:

3 Biotech, 2022, v. 13, n. 1, p. 1, doi. 10.1007/s13205-022-03398-7

By:

da Silva, Larissa;
Donato, Isydorio Alves;
Gonçalves, Cicera Alane Coelho;
Scherf, Jackelyne Roberta;
dos Santos, Hélcio Silva;
Mori, Edna;
Coutinho, Henrique Douglas Melo;
da Cunha, Francisco Assis Bezerra

Publication type:

Article

Antibacterial and Inhibitory Activity of Nora and Mepa Efflux Pumps of Estragole Complexed to β-Cyclodextrin (ES/β-CD) In Vitro Against Staphylococcus aureus Bacteria, Molecular Docking and MPO-Based Pharmacokinetics Prediction.

Published in:

Pharmaceutics, 2024, v. 16, n. 11, p. 1469, doi. 10.3390/pharmaceutics16111469

By:

Costa, Roger Henrique Sousa da;
Pessoa, Renata Torres;
Silva, Eduardo dos Santos;
Araujo, Isaac Moura;
Gonçalves, Sheila Alves;
Rocha, Janaína Esmeraldo;
Pereira Junior, Francisco Nascimento;
Oliveira, Naiara Cipriano;
Oliveira, Victor Moreira de;
Rocha, Matheus Nunes da;
Marinho, Emmanuel Silva;
Kelly Gomes de Carvalho, Natália;
Galberto Martins da Costa, José;
Santos, Hélcio Silva dos;
Menezes, Irwin Rose Alencar de

Publication type:

Article

Evaluation of Emulsification Techniques to Optimize the Properties of Chalcone Nanoemulsions for Antifungal Applications.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 11, p. 1442, doi. 10.3390/ph17111442

By:

Nascimento, Joice Farias do;
Abreu, Flavia Oliveira Monteiro da Silva;
Holanda, Taysse;
Oliveira dos Santos Fontenelle, Raquel;
Prado, Júlio César Sousa;
Marinho, Emmanuel Silva;
da Rocha, Matheus Nunes;
Guedes, Jesyka Macêdo;
Cavalcanti, Bruno Coelho;
Ribeiro, Wesley Lyeverton Correia;
Marinho, Márcia Machado;
Santos, Helcio Silva dos

Publication type:

Article

Investigation of the anti-leishmanial potential of triazole-linked carvacrol–coumarin derivatives: a docking, molecular dynamics, MM/GBSA toxicity approach.

Published in:

Journal of the Iranian Chemical Society, 2025, v. 22, n. 3, p. 459, doi. 10.1007/s13738-024-03166-9

By:

Roberto, Caio Henrique Alexandre;
de Sousa, Damião Sampaio;
da Silva Mendes, Francisco Rogenio;
de Oliveira, Lorena Mayana Beserra;
Teixeira, Alexandre Magno Rodrigues;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking.

Published in:

Biological Chemistry, 2024, v. 405, n. 11/12, p. 727, doi. 10.1515/hsz-2024-0068

By:

Ali, Arif;
de Almeida, Igor Moreira;
Magalhães, Emanuel Paula;
Guedes, Jesyka Macedo;
Cajazeiras, Francisco Ferdinando Mesquita;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
de Menezes, Ramon Róseo Paula Pessoa Bezerra;
Sampaio, Tiago Lima;
Santos, Hélcio Silva dos;
da Silva Júnior, Geraldo Bezerra;
Martins, Alice Maria Costa

Publication type:

Article

Screening of Potential Inhibitors Targeting the Main Protease Structure of SARS-CoV-2 via Molecular Docking, and Approach with Molecular Dynamics, RMSD, RMSF, H-Bond, SASA and MMGBSA.

Published in:

Molecular Biotechnology, 2024, v. 66, n. 8, p. 1919, doi. 10.1007/s12033-023-00831-x

By:

da Fonseca, Aluísio Marques;
Caluaco, Bernardino Joaquim;
Madureira, Junilson Martinho Canjanja;
Cabongo, Sadrack Queque;
Gaieta, Eduardo Menezes;
Djata, Faustino;
Colares, Regilany Paulo;
Neto, Moises Maia;
Fernandes, Carla Freire Celedonio;
Marinho, Gabrielle Silva;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

In Silico Study in MPO and Molecular Docking of the Synthetic Drynaran Analogues Against the Chronic Tinnitus: Modulation of the M1 Muscarinic Acetylcholine Receptor.

Published in:

Molecular Biotechnology, 2024, v. 66, n. 2, p. 254, doi. 10.1007/s12033-023-00748-5

By:

da Rocha, Matheus Nunes;
da Fonseca, Aluísio Marques;
Dantas, Adriana Nogueira Machado;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Gabrielle Silva

Publication type:

Article

Chemical composition determination and evaluation of the antibacterial activity of essential oils from Ruellia asperula (Mart. Ex Ness) Lindau and Ruellia paniculata L. against oral streptococci.

Published in:

Natural Product Research, 2023, v. 37, n. 2, p. 333, doi. 10.1080/14786419.2021.1960521

By:

Vasconcelos, Ariana Azevedo;
Veras, Idia Nara de Sousa;
Vasconcelos, Mayron Alves de;
Andrade, Alexandre Lopes;
dos Santos, Hélcio Silva;
Bandeira, Paulo Nogueira;
Souza, Elnatan Bezerra de;
Albuquerque, Maria Rose Jane Ribeiro;
Teixeira, Edson Holanda

Publication type:

Article

Biocatalysis and in silico study of coconut water peroxidase: A valuable alternative for sustainable and efficient organic synthesis processes.

Published in:

Biocatalysis & Biotransformation, 2025, v. 43, n. 3, p. 280, doi. 10.1080/10242422.2025.2486628

By:

Pinto, Francisco das Chagas Lima;
Bongua, Júnior Inácio;
Paiva, Maria Mabelle Pereira Costa;
de Lemos, Telma Leda Gomes;
Colares, Regilany Paulo;
Marinho, Emmanuel Silva;
Santos, Hélcio Silva dos;
de Oliveira, Mauro Macedo;
da Fonseca, Aluísio Marques

Publication type:

Article

Antibacterial and Antibiofilm Activities of Hydralazine, an Antihypertensive Drug: In Vitro and In Silico Approaches.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 3, p. 286, doi. 10.3390/antibiotics14030286

By:

Pereira, Antônio Mateus Gomes;
da Silva, Benise Ferreira;
Araujo, Ingrid Maria Frota;
Aguiar, Francisco Kauê Carvalho;
Coelho, Paulo Adenes Teixeira;
Costa, Renata Albuquerque;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
Nunes, João Victor Serra;
Carneiro, Victor Alves;
Santos, Hélcio Silva dos

Publication type:

Article

Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach.

Published in:

Future Journal of Pharmaceutical Sciences, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s43094-025-00783-w

By:

Silva, Jacilene;
da Rocha, Matheus Nunes;
de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
Lúcio, Francisco Nithael Melo;
Marinho, Márcia Machado;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Structural, Vibrational and Electrochemical Analysis and Antibacterial Potential of Isomeric Chalcones Derived from Natural Acetophenone.

Published in:

Applied Sciences (2076-3417), 2020, v. 10, n. 14, p. 4713, doi. 10.3390/app10144713

By:

Silva, Priscila Teixeira da;
Freitas, Thiago Sampaio de;
Sena, Diniz Maciel;
Bandeira, Paulo Nogueira;
Julião, Murilo Ségio da Silva;
Marinho, Emmanuel Silva;
Alcanfor, Ana Aline Coêlho;
Marinho, Emanuelle Machado;
Lima-Neto, Pedro de;
Nogueira, Carlos Emídio Sampaio;
Coutinho, Henrique Douglas Melo;
Leal, Antonio Linkoln Alves Borges;
Barreto, Humberto Medeiros;
Martins, Natália;
Rodrigues Teixeira, Alexandre Magno;
Santos, Hélcio Silva dos

Publication type:

Article

Robinin Isolated From Solanum Asperum Exhibits Pharmacological Actions in the Central Nervous System of Adult Zebrafish (Danio rerio).

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 5, p. 1, doi. 10.1002/cbdv.202402173

By:

Lemos, Cecília Guimarães;
Wlisses da Silva, Antonio;
Maciel, Jéssica Bezerra;
Ferreira, Maria Kueirislene Amâncio;
Nunes da Rocha, Matheus;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
Pinto, Francisco das Chagas Lima;
Loiola, Otília Deusdênia;
de Castro Gomes, Andreia Ferreira;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Hydralazine and Hydrazine Derivatives: Properties, Applications, and Repositioning Potential.

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 3, p. 1, doi. 10.1002/cbdv.202401561

By:

Romão, Ivana Carneiro;
Siqueira, Sônia Maria Costa;
Silva Abreu, Flávia Oliveira Monteiro da;
Santos, Hélcio Silva dos

Publication type:

Article

Anxiolytic and Anticonvulsant Potential of Biosynthetic Limonene Derivatives in Adult Zebrafish.

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 2, p. 1, doi. 10.1002/cbdv.202401663

By:

Cavalcante, Rafaela Mesquita Bastos;
Ferreira, Maria Kueirislene Amâncio;
Wlisses da Silva, Antonio;
Mendes, Francisco Rogenio da Silva;
Guimarães Lemos, Cecília;
Bezerra Maciel, Jéssica;
Rocha Cavalcante, Thaís;
Silva Marinho, Emmanuel;
Alencar de Menezes, Jane Eire Silva;
dos Santos, Helcio Silva

Publication type:

Article

Anxiolytic and Anticonvulsant Effects of Fisetin Isolated from Bauhinia pentandra on Adult Zebrafish (Danio rerio).

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 11, p. 1, doi. 10.1002/cbdv.202401207

By:

da Silva, Horlando Carlota;
das Chagas Lima Pinto, Francisco;
Silva Marinho, Emmanuel;
Alencar de Menezes, Jane Eire Silva;
Kueirislene Amâncio Ferreira, Maria;
da Silva, Antonio Wlisses;
Machado Marinho, Emanuelle;
Marinho, Márcia Machado;
Pessoa Bezerra de Menezes, Ramon Róseo Paula;
Washington Cavalcante, John;
Silva dos Santos, Hélcio;
Pessoa, Otília Deusdênia Loiola;
Santiago, Gilvandete Maria Pinheiro

Publication type:

Article

Effect of Cinnamaldehyde Chalcone on Behavior in Adult Zebrafish (Danio rerio): In Silico Approach.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 8, p. 1, doi. 10.1002/cbdv.202400935

By:

Carneiro Romão, Ivana;
Costa Siqueira, Sônia Maria;
Amâncio Ferreira, Maria Kueirislene;
Wlisses da Silva, Antonio;
Machado Marinho, Márcia;
Ferreira Ribeiro, Walber Henrique;
de Castro Gomes, Andreia Ferreira;
Alencar de Menezes, Jane Eire Silva;
dos Santos, Hélcio Silva

Publication type:

Article

Withanicandrin Isolated from Datura Ferox Promotes Antinociception by Modulating the Asics and TRPS Channels and Anti‐Inflammation in Adult Zebrafish.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 7, p. 1, doi. 10.1002/cbdv.202400538

By:

Maciel, Jéssica Bezerra;
Liberato, Hortência Ribeiro;
da Silva, Antônio Wlisses;
da Silva, João Pedro Vieira;
das Chagas L. Pinto, Francisco;
de Lima Rebouças, Emanuela;
da Silva, Francisco Sydney Henrique;
Ferreira, Maria Kueirislene Amâncio;
Marinho, Marcia Machado;
Marinho, Emmanuel Silva;
Pessoa, Otília Deusdênia Loiola;
de Barros Silva, Paulo Goberlânio;
Coelho‐de‐Souza, Andrelina Noronha;
Guedes, Maria Izabel Florindo;
de Castro Gomes, Andreia Ferreira;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Neuromodulation of Acid‐Sensitive Ion Channels (ASICs) and Anti‐Inflammatory Potential by Lichenxanthone in Adult Zebrafish (Danio rerio): Experimental and Docking Studies.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 4, p. 1, doi. 10.1002/cbdv.202400063

By:

Ribeiro Liberato, Hortência;
Bezerra Maciel, Jéssica;
Wlisses Da Silva, Antônio;
Eduarda Uchoa Bezerra, Maria;
San De Oliveira Brito, Luana;
Silva, Jacilene;
Kuerislene Amâncio Ferreira, Maria;
Machado Marinho, Marcia;
Marinho, Gabrielle S;
Deusdênia Loiola Pessoa, Otília;
Guedes, Maria Izabel F;
Goberlânio De Barros Silva, Paulo;
Ferreira de Castro Gomes, Andreia;
Silva Alencar De Menezes, Jane Eire;
Silva Dos Santos, Hélcio

Publication type:

Article

Chemical Profile and Biological Potential of Scaptotrigona Bee Products (Hymenoptera, Apidae, Meliponini): An Review.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 4, p. 1, doi. 10.1002/cbdv.202301962

By:

de Sousa Silveira, Zildene;
Silva Macêdo, Nair;
de Menezes Dantas, Débora;
Vieira Brito, Samuel;
Silva dos Santos, Helcio;
Regis de Sousa Gomes, Renata Valéria;
Douglas Melo Coutinho, Henrique;
Bezerra da Cunha, Francisco Assis;
Vanusa da Silva, Márcia

Publication type:

Article

Molecular Docking and GC/MS‐Based Approach for Identification of Anxiolytic Alkaloids from Griffinia (Amaryllidaceae) Species in a Zebrafish Model.

Published in:

Chemistry & Biodiversity, 2024, v. 21, n. 3, p. 1, doi. 10.1002/cbdv.202302122

By:

Leite, Elder Luis Lima;
Sheila de Queiroz Souza, Ana;
Riceli Vasconcelos Ribeiro, Paulo;
de Cássia Alves Pereira, Rita;
Florêncio Martins, Natália;
Kueirislene Amâncio Ferreira, Maria;
Silva Alencar de Menezes, Jane Eire;
Silva dos Santos, Hélcio;
Deusdênia Loiola Pessoa, Otília;
Marques Canuto, Kirley

Publication type:

Article

Floral Visitation, Phytochemical and Biological Activities of Bioproducts from Tetragonisca angustula (Hymenoptera, Apidae, Meliponini): A Review.

Published in:

Chemistry & Biodiversity, 2023, v. 20, n. 12, p. 1, doi. 10.1002/cbdv.202301451

By:

Silva Macêdo, Nair;
de Sousa Silveira, Zildene;
da Silva Sousa, Ângella Eduarda;
Menezes Dantas, Débora;
Bispo Monteiro, Amanda Lins;
Silva dos Santos, Helcio;
Bezerra da Cunha, Francisco Assis

Publication type:

Article

Chemical Composition Determination and Evaluation of the Antimicrobial Activity of Essential Oil from Croton blanchetianus (Euphorbiaceae) against Clinically Relevant Bacteria.

Published in:

Chemistry & Biodiversity, 2023, v. 20, n. 1, p. 1, doi. 10.1002/cbdv.202200777

By:

Nunes, Aluska Kelly A.;
Araújo Malveira, Ellen;
Lopes Andrade, Alexandre;
Barbosa da Silva, Wildson Max;
de Morais, Selene Maia;
Silva dos Santos, Hélcio;
Cavalcanti de Albuquerque, Cynthia;
Holanda Teixeira, Edson;
do Nascimento Souza, Diego Nathan;
Alves de Vasconcelos, Mayron

Publication type:

Article

Assessment In vitro and In silico of the Activity of Thiadiazines as NorA Efflux Pump Inhibitors.

Published in:

Current Microbiology, 2024, v. 81, n. 10, p. 1, doi. 10.1007/s00284-024-03836-0

By:

de Araújo, Ana Carolina Justino;
Freitas, Priscilla Ramos;
Araújo, Isaac Moura;
de Oliveira Borges, João Arthur;
Gonçalves, Sheila Alves;
Paulo, Cícera Laura Roque;
Almeida, Ray Silva;
de Moraes Oliveira-Tintino, Cícera Datiane;
de Araújo-Neto, José Bezerra;
dos Santos Nascimento, Igor José;
de Araújo-Júnior, João Xavier;
da Silva-Júnior, Edeildo Ferreira;
de Aquino, Thiago Mendonça;
Junior, Francisco Jaime Bezerra Mendonça;
Marinho, Emmanuel Silva;
dos Santos, Helcio Silva;
de Alencar Menezes, Irwin Rose;
Tintino, Saulo Relison;
Coutinho, Henrique Douglas Melo;
Braga, Maria Flaviana Bezerra Morais

Publication type:

Article

Antibacterial and Antibiofilm Activity of Croton urticifolius Lam. Essential Oil Via Membrane Disruption.

Published in:

Current Microbiology, 2024, v. 81, n. 8, p. 1, doi. 10.1007/s00284-024-03779-6

By:

Malveira, Ellen Araújo;
Nunes, Aluska Kelly A.;
Andrade, Alexandre Lopes;
Melo, Gabriel Lucas Carvalho;
da Silva, Wildson Max Barbosa;
de Morais, Selene Maia;
dos Santos, Hélcio Silva;
de Lima, Leandro Bezerra;
de Albuquerque, Cynthia Cavalcanti;
do Nascimento Souza, Diego Nathan;
Teixeira, Edson Holanda;
de Vasconcelos, Mayron Alves

Publication type:

Article

Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg.

Published in:

Current Microbiology, 2021, v. 78, n. 5, p. 1926, doi. 10.1007/s00284-021-02449-1

By:

do Vale, Jean Parcelli Costa;
Vasconcelos, Mayron Alves;
Arruda, Francisco Vassiliepe Sousa;
Firmino, Nairley Cardoso Sá;
Pereira, Anna Luísa;
Andrade, Alexandre Lopes;
Saker-Sampaio, Silvana;
Sampaio, Alexandre Holanda;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
Marinho, Márcia Machado;
Rodrigues, Tigressa Helena Soares;
Teixeira, Edson Holanda;
dos Santos, Hélcio Silva

Publication type:

Article

Seasonality Effects on Antibacterial and Antibiotic Potentiating Activity against Multidrug-Resistant Strains of Escherichia coli and Staphylococcus aureus and ATR-FTIR Spectra of Essential Oils from Vitex gardneriana Leaves.

Published in:

Current Microbiology, 2020, v. 77, n. 12, p. 3969, doi. 10.1007/s00284-020-02226-6

By:

Pereira, Raimundo Luiz Silva;
Freitas, Thiago Sampaio de;
Freitas, Priscilla Ramos;
Araújo, Ana Carolina Justino de;
Campina, Fábia Ferreira;
Fidelis, Kleber Ribeiro;
Vale, Jean Parcelli Costa do;
Barreto, Antônio César Honorato;
Coutinho, Henrique Douglas Melo;
Bandeira, Paulo Nogueira;
Teixeira, Alexandre Magno Rodrigues;
Santos, Hélcio Silva dos

Publication type:

Article

Chemical Composition, Antibacterial and Inhibitory Activity of the Efflux Pump of Essential Oils from Croton piauhiensis Müll.

Published in:

Nutraceuticals (1661-3821), 2023, v. 3, n. 4, p. 591, doi. 10.3390/nutraceuticals3040042

By:

Cruz, Beatriz Gonçalves;
de Freitas, Thiago Sampaio;
Costa, Maria do Socorro;
da Silva, Ana Raquel Pereira;
Coutinho, Henrique Douglas Melo;
de Morais, Selene Maia;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
Silva dos Santos, Hélcio

Publication type:

Article

Antioxidant Activity and Anxiolytic Effect of Cnidoscolus quercifolius Pohl Stem Bark Extract in Zebrafish.

Published in:

Future Pharmacology, 2025, v. 5, n. 2, p. 16, doi. 10.3390/futurepharmacol5020016

By:

do Nascimento, Joice Barbosa;
da Silva Mendes, Johnatan Wellisson;
Viturino, José Jonas Ferreira;
Inácio da Silva, Maria;
Pereira da Silva, Mariana;
Duarte Leite, Débora Odília;
Marinho, Emmanuel Silva;
de Menezes, Jane Eire Silva Alencar;
Santos, Hélcio Silva dos;
da Costa, José Galberto Martins

Publication type:

Article

Anticonvulsant, Anticholinesterase and Cytoprotective Effects of the Aqueous Extract of Lippia sidoides Cham.

Published in:

Plants (2223-7747), 2024, v. 13, n. 21, p. 3034, doi. 10.3390/plants13213034

By:

Camilo, Cicera Janaine;
Leite, Débora Odília Duarte;
de Carvalho, Natália Kelly Gomes;
Castro, José Walber Gonçalves;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Helcio Silva;
Silva, Joanda Paolla Raimundo;
Alves, Daniela Ribeiro;
de Morais, Selene Maia;
Rodrigues, Fabíola Fernandes Galvão;
da Costa, José Galberto Martins

Publication type:

Article

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species.

Published in:

Plants (2223-7747), 2023, v. 12, n. 8, p. 1675, doi. 10.3390/plants12081675

By:

Nonato, Carla de Fatima Alves;
de Melo, Emerson Vinicius Silva;
Camilo, Cicera Janaine;
Ferreira, Maria Kueirislene Amâncio;
de Meneses, Jane Eire Alencar;
da Silva, Antonio Wlisses;
Santos, Hélcio Silva dos;
Ribeiro-Filho, Jaime;
Paolla Raimundo e Silva, Joanda;
Tavares, Josean Fechine;
Menezes, Irwin Rose Alencar de;
Coutinho, Henrique Douglas Melo;
Kowalska, Grażyna;
Baj, Tomasz;
Kowalski, Radosław;
da Costa, José Galberto Martins

Publication type:

Article

Synthesis, antibiotic modifying activity, ADMET study and molecular docking of chalcone (E)-3-(2,4-dichlorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying MepA efflux pumps.

Published in:

Archives of Microbiology, 2022, v. 204, n. 1, p. 1, doi. 10.1007/s00203-021-02666-z

By:

Rocha, Janaína Esmeraldo;
de Freitas, Thiago Sampaio;
da Cunha Xavier, Jayze;
Pereira, Raimundo Luiz Silva;
Pereira, Francisco Nascimento Jr;
Nogueira, Carlos Emídio Sampaio;
Marinho, Márcia Machado;
Bandeira, Paulo Nogueira;
Fernandes, Maria Alyce Albuquerque;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
dos Santos, Hélcio Silva;
Coutinho, Henrique Douglas Melo

Publication type:

Article

Chemical composition and potentiating action of Norfloxacin mediated by the essential oil of Piper caldense C.D.C. against Staphylococcus aureus strains overexpressing efflux pump genes.

Published in:

Archives of Microbiology, 2021, v. 203, n. 7, p. 4727, doi. 10.1007/s00203-021-02393-5

By:

Leal, Antonio Linkoln Alves Borges;
Bezerra, Camila Fonseca;
Confortin, Camila;
da Silva, Luiz Everson;
Marinho, Emanuelle Machado;
Marinho, Márcia Machado;
Vasconcelos, Mayron Alves;
da Silva, Terezinha Gonçalves;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
Coutinho, Henrique Douglas Melo;
Barreto, Humberto Medeiros;
dos Santos, Hélcio Silva

Publication type:

Article

Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone Derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone.

Published in:

Journal of Renewable Materials, 2024, v. 12, n. 2, p. 285, doi. 10.32604/jrm.2023.043919

By:

da Silva Abreu, Flavia Oliveira Monteiro;
Holanda, Taysse;
Farias do Nascimento, Joice;
Nascimento Pinheiro, Henety;
Menezes Castelo, Rachel;
Silva dos Santos, Hélcio;
Benincá, Thais;
da Silva Malheiros, Patrícia;
Sousa Prado, Júlio César;
de Oliveira Fontenelle, Raquel;
de Camargo Forte, Maria Madalena

Publication type:

Article

Leishmanicidal and healing effects of 3β,6β,16β-trihydroxy lup-20 (29)-ene isolated from Combretum leprosum on Leishmania braziliensis infection in vitro and in vivo.

Published in:

PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0287665

By:

Sombra Santos, Aline;
de Castro Rodrigues, Naya Lúcia;
Marciano Fonseca, Francisco Rafael;
Braga Fayão Oliveira, Nathalia;
Oliveira Loucard, Bianca;
Fernandes Heredia, Fabíola;
Albuquerque Gomes Nogueira, Teresa Neuma;
Monteiro Abreu, Ticiana;
Silva dos Santos, Hélcio;
Holanda Teixeira, Edson;
Almeida Moreira Leal, Luzia Kalyne;
Brandim Gomes, Regis Bernardo;
Romero Teixeira, Clarissa;
Teixeira, Maria Jania

Publication type:

Article

Insights of potential trypanocidal effect of the synthetic derivative (2E)-1-(4-aminophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one: in vitro assay, MEV analysis, quantum study, molecular docking, molecular dynamics, MPO analysis, and predictive ADMET.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 10, p. 7797, doi. 10.1007/s00210-024-03138-z

By:

Marinho, Márcia Machado;
da Rocha, Matheus Nunes;
Magalhães, Emanuel Paula;
Ribeiro, Lyanna Rodrigues;
Roberto, Caio Henrique Alexandre;
de Queiroz Almeida-Neto, Francisco Wagner;
Monteiro, Marília Lopes;
Nunes, João Victor Serra;
de Menezes, Ramon Róseo Paula Pessoa Bezerra;
Marinho, Emmanuel Silva;
de Lima Neto, Pedro;
Martins, Alice Maria Costa;
dos Santos, Hélcio Silva

Publication type:

Article

Casbane Diterpene as a Promising Natural Antimicrobial Agent against Biofilm-Associated Infections.

Published in:

Molecules, 2011, v. 16, n. 1, p. 190, doi. 10.3390/molecules16010190

By:

Carneiro, Victor Alves;
dos Santos, Hélcio Silva;
Sousa Arruda, Francisco Vassiliepe;
Bandeira, Paulo Nogueira;
Albuquerque, Maria Rose Jane Ribeiro;
Pereira, Maria Olívia;
Henriques, Mariana;
Cavada, Benildo Sousa;
Teixeira, Edson Holanda

Publication type:

Article

Antispasmodic effects of a new kaurene diterpene isolated from Croton argyrophylloides on rat airway smooth muscle.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 8, p. 1155, doi. 10.1111/j.2042-7158.2012.01494.x

By:

Aguiar, Liza Araújo;
Porto, Romulo Sousa;
Lahlou, Saad;
Ceccatto, Vânia Marilande;
Barbosa, Roseli;
Lemos, Telma Leda Gomes;
dos Santos, Hélcio Silva;
Coelho-de-Souza, Andrelina Noronha;
Magalhães, Pedro Jorge Caldas;
Zin, Walter Araújo;
Leal-Cardoso, José Henrique

Publication type:

Article

Antimicrobial Effect of the Triterpene 3 [beta] ,6 [beta] ,16 [beta] -Trihydroxylup-20(29)-ene on Planktonic Cells and Biofilms from Gram Positive and Gram Negative Bacteria.

Published in:

2014

By:

Evaristo, Francisco Flávio Vasconcelos;
Albuquerque, Maria Rose Jane R;
Dos Santos, Hélcio Silva;
Bandeira, Paulo Nogueira;
Avila, Fábio do Nascimento;
da Silva, Bruno Rocha;
Vasconcelos, Ariana Azevedo;
Rabelo, Erica de Menezes;
Nascimento-Neto, Luiz Gonzaga;
Arruda, Francisco Vassiliepe Sousa;
Vasconcelos, Mayron Alves;
Carneiro, Victor Alves;
Cavada, Benildo Sousa;
Teixeira, Edson Holanda

Publication type:

Journal Article

Antibacterial and Antioxidant Activities of Derriobtusone A Isolated from Lonchocarpus obtusus.

Published in:

2014

By:

Vasconcelos, Mayron Alves;
Arruda, Francisco Vassiliepe Sousa;
de Alencar, Daniel Barroso;
Saker-Sampaio, Silvana;
Albuquerque, Maria Rose Jane Ribeiro;
Dos Santos, Hélcio Silva;
Bandeira, Paulo Nogueira;
Pessoa, Otília Deusdênia Loiola;
Cavada, Benildo Sousa;
Henriques, Mariana;
Pereira, Maria Olivia;
Teixeira, Edson Holanda

Publication type:

Journal Article

Antibacterial and Antioxidant Activities of Derriobtusone A Isolated from Lonchocarpus obtusus.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/248656

By:

Vasconcelos, Mayron Alves;
Sousa Arruda, Francisco Vassiliepe;
De Alencar, Daniel Barroso;
Saker-Sampaio, Silvana;
Ribeiro Albuquerque, Maria Rose Jane;
Dos Santos, Hélcio Silva;
Bandeira, Paulo Nogueira;
Loiola Pessoa, Otília Deusdênia;
Cavada, Benildo Sousa;
Henriques, Mariana;
Pereira, Maria Olivia;
Teixeira, Edson Holanda

Publication type:

Article

Synthesis, molecular docking, ADMET, and evaluation of the anxiolytic effect in adult zebrafish of synthetic chalcone (E)‐3‐(4‐(dimethylamino)phenyl)‐1‐(2‐hydroxyphenyl)prop‐2‐en‐1‐one: An in vivo and in silico approach

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 2, p. 290, doi. 10.1111/fcp.12960

By:

Santos Oliveira, Larissa;
Kueirislene Amâncio Ferreira, Maria;
Wagner de Queiroz Almeida‐Neto, Francisco;
Wlisses da Silva, Antonio;
Ivo Lima Pinto Filho, José;
Nunes da Rocha, Matheus;
Machado Marinho, Emanuelle;
Henrique Ferreira Ribeiro, Walber;
Machado Marinho, Márcia;
Silva Marinho, Emmanuel;
Eire Silva Alencar de Menezes, Jane;
dos Santos, Hélcio Silva

Publication type:

Article

Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains.

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 1, p. 84, doi. 10.1111/fcp.12950

By:

de Araújo, Ana Carolina Justino;
Freitas, Priscilla Ramos;
Araújo, Isaac Moura;
Siqueira, Gustavo Miguel;
de Oliveira Borges, João Arthur;
Alves, Daniel Sampaio;
Miranda, Gustavo Marinho;
dos Santos Nascimento, Igor José;
de Araújo‐Júnior, João Xavier;
da Silva‐Júnior, Edeildo Ferreira;
de Aquino, Thiago Mendonça;
Junior, Francisco Jaime Bezerra Mendonça;
Marinho, Emmanuel Silva;
dos Santos, Helcio Silva;
Tintino, Saulo Relison;
Coutinho, Henrique Douglas Melo

Publication type:

Article

Synthesis, spectroscopic characterization, and antibacterial activity of chalcone (2E)‐1‐(3′‐aminophenyl)‐3‐(4‐dimethylaminophenyl)‐prop‐2‐en‐1‐one against multiresistant Staphylococcus aureus carrier of efflux pump mechanisms and β‐lactamase

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 1, p. 60, doi. 10.1111/fcp.12938

By:

da Silva, Larissa;
Donato, Isydório Alves;
Bezerra, Suieny Rodrigues;
dos Santos, Hélcio Silva;
Bandeira, Paulo Nogueira;
do Nascimento, Maria Thalia Ramos;
Guedes, Jesyka Macêdo;
Freitas, Priscila Ramos;
de Araújo, Ana Carolina Justino;
de Freitas, Thiago Sampaio;
Coutinho, Henrique Douglas Melo;
de Matos, Yedda Maria Lobo Soares;
de Oliveira, Lígia Cláudia Castro;
da Cunha, Francisco Assis Bezerra

Publication type:

Article

Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one.

Published in:

Fundamental & Clinical Pharmacology, 2022, v. 36, n. 6, p. 1066, doi. 10.1111/fcp.12785

By:

Hemília de Souza Nunes, Paula;
Sampaio de Freitas, Thiago;
Esmeraldo Rocha, Janaína;
Luiz Silva Pereira, Raimundo;
Machado Marinho, Marcia;
de Oliveira, Mateus Rodrigues;
Santos Oliveira, Larissa;
Machado Marinho, Emanuelle;
Silva Marinho, Emmanuel;
Sousa Aquino, Silvia;
Emidio Sampaio Nogueira, Carlos;
Douglas Melo Coutinho, Henrique;
Nogueira Bandeira, Paulo;
Magno Rodrigues Teixeira, Alexandre;
dos Santos, Hélcio Silva

Publication type:

Article

Hypoglycemic effect on adult zebrafish (Danio rerio) of the 3β‐6β‐16β‐trihydroxylup‐20(29)‐ene triterpene isolated from Combretum leprosum leaves in vivo and in silico approach.

Published in:

Fundamental & Clinical Pharmacology, 2022, v. 36, n. 5, p. 818, doi. 10.1111/fcp.12776

By:

Coutinho, Marnielle Rodrigues;
da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene Amâncio;
de Lima Rebouças, Emanuela;
Mendes, Francisco Rogênio S.;
Teixeira, Edson Holanda;
Marinho, Emanuelle Machado;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
Teixeira, Alexandre Magno Rodrigues;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Structure and Ligand Based Virtual Screening and MPO Topological Analysis of Triazolo Thiadiazepine-fused Coumarin Derivatives as Anti-Parkinson Drug Candidates.

Published in:

Molecular Biotechnology, 2025, v. 67, n. 6, p. 2339, doi. 10.1007/s12033-024-01200-y

By:

Pereira, Antônio Mateus Gomes;
de Oliveira, Victor Moreira;
da Rocha, Matheus Nunes;
Roberto, Caio Henrique Alexandre;
Cajazeiras, Francisco Ferdinando Mesquita;
Guedes, Jesyka Macêdo;
Marinho, Márcia Machado;
Teixeira, Alexandre Magno Rodrigues;
Marinho, Emmanuel Silva;
de Lima-Neto, Pedro;
dos Santos, Hélcio Silva

Publication type:

Article

Ligand and structure-based virtual screening approaches in drug discovery: minireview.

Published in:

Molecular Diversity, 2025, v. 29, n. 3, p. 2799, doi. 10.1007/s11030-024-10979-6

By:

da Rocha, Matheus Nunes;
de Sousa, Damião Sampaio;
da Silva Mendes, Francisco Rogenio;
dos Santos, Helcio Silva;
Marinho, Gabrielle Silva;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva

Publication type:

Article

In Vitro and In Silico Study of the Inhibitory Potential of Riparins I, II, III, and IV on the NorA Efflux Pump of Staphylococcus aureus.

Published in:

ChemistrySelect, 2025, v. 10, n. 23, p. 1, doi. 10.1002/slct.202500292

By:

Rodrigues dos Santos Barbosa, Cristina;
Rocha, Janaína Esmeraldo;
Silveira, Zildene de Sousa;
de Araújo, Ana Carolina Justino;
Freitas, Priscilla Ramos;
Oliveira‐Tintino, Cícera Datiane de Morais;
Macêdo, Nair Silva;
de Freitas, Thiago Sampaio;
da Cunha, Francisco Assis Bezerra;
Marinho, Emmanuel Silva;
de Sousa, Gabriela Ribeiro;
Barbosa‐Filho, José Maria;
de Souza‐Ferrari, Jailton;
Silva dos Santos, Hélcio;
Coutinho, Henrique Douglas Melo

Publication type:

Article

Antitrypanosomal Potential of Chalcone‐Based Ursolic Acid Derivatives via Ligand‐Based Virtual Screening, DMPK Analyses, Molecular Dynamics Simulation, and MM/GBSA Binding Energy.

Published in:

ChemistrySelect, 2024, v. 9, n. 44, p. 1, doi. 10.1002/slct.202402673

By:

Nunes, João Victor Serra;
da Rocha, Matheus Nunes;
de de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Márcia Machado;
Martins, Alice Maria Costa

Publication type:

Article