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Polygenic Risk Score of Longevity Predicts Longer Survival Across an Age Continuum.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2021, v. 76, n. 5, p. 750, doi. 10.1093/gerona/glaa289
By:
- Tesi, Niccoló;
- van der Lee, Sven J.;
- Hulsman, Marc;
- Jansen, Iris E.;
- Stringa, Najada;
- van Schoor, Natasja M.;
- Scheltens, Philip;
- van der Flier, Wiesje M.;
- Huisman, Martijn;
- Reinders, Marcel J. T.;
- Holstege, Henne
Publication type:
Article
Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 10, p. 3522, doi. 10.1093/brain/awae090
By:
- Reus, Lianne M;
- Jansen, Iris E;
- Tijms, Betty M;
- Visser, Pieter Jelle;
- Tesi, Niccoló;
- Lee, Sven J van der;
- Vermunt, Lisa;
- Peeters, Carel F W;
- Groot, Lisa A De;
- Hok-A-Hin, Yanaika S;
- Chen-Plotkin, Alice;
- Irwin, David J;
- Hu, William T;
- Meeter, Lieke H;
- Swieten, John C van;
- Holstege, Henne;
- Hulsman, Marc;
- Lemstra, Afina W;
- Pijnenburg, Yolande A L;
- Flier, Wiesje M van der
Publication type:
Article
Association of MGMT and BIN1 genes with Alzheimer's disease risk across sex and APOE ε4 status.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2282, doi. 10.1002/alz.13550
By:
- Le Borgne, Julie;
- Amouyel, Philippe;
- Andreassen, Ole;
- Frikke‐Schmidt, Ruth;
- Hiltunen, Mikko;
- Ingelsson, Martin;
- Ramirez, Alfredo;
- Rossi, Giacomina;
- Ruiz, Agustin;
- Sanchez‐Juan, Pascual;
- Sims, Rebecca;
- Sleegers, Kristel;
- Tsolaki, Magda;
- van der Lee, Sven J.;
- Williams, Julie;
- Lambert, Jean‐Charles;
- Bellenguez, Céline
Publication type:
Article
Dissecting the shared genetic basis of Alzheimer's disease and hippocampal volumes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082963
By:
- Jiang, Chenyang;
- van der Lee, Sven J;
- van der Flier, Wiesje M.;
- Tijms, Betty M.;
- Reus, Lianne M.
Publication type:
Article
Replication of HLA‐DRB1*04:04 allele subtype protective effect against Alzheimer's Disease in cognitively healthy centenarians using long‐read sequencing.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082981
By:
- Sirvent, Daniel Alvarez;
- Salazar, Alex N;
- Tesi, Niccoló;
- Hulsman, Marc;
- van der Lee, Sven J;
- Pijnenburg, Yolande A.L.;
- van der Flier, Wiesje M.;
- Holstege, Henne
Publication type:
Article
Can escapees of familial AD help identify protective factors? A case report of an extremely resilient PSEN1 carrier.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 22, p. 1, doi. 10.1002/alz.074216
By:
- Smulders, Michelle N.C.A.;
- Dijkstra, Janna I.R.;
- Visser, Denise;
- Vermunt, Lisa;
- Giessen, Elsmarieke;
- Pijnenburg, Yolande A.L.;
- Holstege, Henne;
- van der Flier, Wiesje M.;
- Ossenkoppele, Rik;
- van der Lee, Sven J
Publication type:
Article
Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: A survey study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079601
By:
- Waterink, Lisa;
- Masselink, Larissa A;
- van der Lee, Sven J;
- Visser, Leonie N.C.;
- Cleutjens, Solange;
- van der Schaar, Jetske;
- van Harten, Argonde C.;
- Scheltens, Philip;
- van der Flier, Wiesje M.;
- Zwan, Marissa D.
Publication type:
Article
The Association Between Levels of Plasma Biomarkers and Cognitive Performance in the Oldest Old.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078964
By:
- Lorenz, Linda M.C.;
- Zhang, Meng;
- Tesi, Niccoló;
- van der Lee, Sven J;
- Hulsman, Marc;
- Gouda, Mariam;
- Sikkes, Sietske A.M.;
- Teunissen, Charlotte E.;
- Holstege, Henne
Publication type:
Article
The Association of Plasma Biomarkers and Survival in the Oldest Old.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078919
By:
- Lorenz, Linda M.C.;
- Tesi, Niccoló;
- van der Lee, Sven J;
- Hulsman, Marc;
- Gouda, Mariam;
- Sikkes, Sietske A.M.;
- Teunissen, Charlotte E.;
- Holstege, Henne
Publication type:
Article
CSF proteomics in autosomal dominant Alzheimer's disease highlights parallels with sporadic disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073682
By:
- van der Ende, Emma L.;
- in 't Veld, Sjors G.J.G.;
- Hanskamp, Iris;
- Van der lee, Sven J;
- Dijkstra, Janna I.R.;
- van Swieten, John C.;
- Irwin, David J.;
- Chen‐Plotkin, Alice;
- Hu, William T.;
- Lemstra, Afina W.;
- Pijnenburg, Yolande A.L.;
- van der Flier, Wiesje M.;
- del Campo, Marta;
- Teunissen, Charlotte E.;
- Vermunt, Lisa
Publication type:
Article
In‐depth evaluation of protein domains improves classification of SORL1 variant pathogenicity in Alzheimer's Disease patients.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080395
By:
- de Waal, Matthijs W J;
- Hulsman, Marc;
- van der Lee, Sven J;
- Andersen, Olav M.;
- Holstege, Henne
Publication type:
Article
Cerebrospinal fluid metabolome‐wide association study of Alzheimer's disease provides insight into molecular pathways.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078688
By:
- Reus, Lianne M.;
- Boltz, Toni;
- Francia, Marcelo;
- Bot, Merel;
- Loohuis, Loes Olde;
- Teunissen, Charlotte E.;
- Ophoff, Roel;
- Tijms, Betty;
- van der Lee, Sven J;
- Visser, Pieter Jelle;
- van der Flier, Wiesje M.;
- Ramesh, Naren
Publication type:
Article
TREM2 Burden associates solely with Alzheimer's Disease, and decreases the Chance to become a Centenarian.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078234
By:
- Dijkstra, Janna I.R.;
- Vermunt, Lisa;
- Biessels, Geert Jan;
- Braber, Anouk;
- Claassen, Jurgen A.H.R.;
- De Deyn, Peter Paul;
- Ghanbari, Mohsen;
- Huisman, Martijn;
- Hulsman, Marc;
- Ramakers, Inez H.G.B.;
- Reinders, Marcel J. T.;
- Seelaar, Harro;
- Tesi, Niccoló;
- Visser, Pieter Jelle;
- van der Flier, Wiesje M.;
- Teunissen, Charlotte E.;
- Holstege, Henne;
- Van Der Lee, Sven J
Publication type:
Article
Identifying Cognitive Resilience Related Genes Among Genetic Risk Loci of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077781
By:
- Carrigan, Maria;
- Van der Lee, Sven J;
- van Loenhoud, Anna C.;
- Bocancea, Diana I.;
- Groot, Colin;
- Barkhof, Frederik;
- Krugers, Harm J.;
- Lucassen, Paul J.;
- van der Flier, Wiesje M.;
- Ossenkoppele, Rik
Publication type:
Article
Cognitively Healthy Centenarians are genetically protected against Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076095
By:
- Tesi, Niccoló;
- Van Der Lee, Sven J;
- Hulsman, Marc;
- van Schoor, Natasja;
- Huisman, Martijn;
- Pijnenburg, Yolande A. L.;
- Flier, Wiesje M.;
- Reinders, Marcel JT;
- Holstege, Henne
Publication type:
Article
Rare copy number variation in the GR@ACE/DEGESCO dementia dataset of spanish population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074012
By:
- de Rojas, Itziar;
- García‐Ribas, Guillermo;
- Sanchez‐Juan, Pascual;
- Perez‐Tur, Jordi;
- Pastor, Pau;
- Bullido, María J.;
- Álvarez‐Martínez, Victoria;
- Real, Luis Miguel;
- Mir, Pablo;
- Piñol‐Ripoll, Gerard;
- García‐Alberca, Jose María;
- Medina, Miguel;
- Sáez, María Eugenia;
- Carracedo, Angel;
- Tárraga, Lluís;
- Boada, Mercè;
- Van Der Lee, Sven J;
- Ruiz, Agustin
Publication type:
Article
In‐depth evaluation of protein domains improves classification of SORL1 variant pathogenicity in Alzheimer's Disease patients.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080395
By:
- de Waal, Matthijs W J;
- Hulsman, Marc;
- van der Lee, Sven J;
- Andersen, Olav M.;
- Holstege, Henne
Publication type:
Article
Cerebrospinal fluid metabolome‐wide association study of Alzheimer's disease provides insight into molecular pathways.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078688
By:
- Reus, Lianne M.;
- Boltz, Toni;
- Francia, Marcelo;
- Bot, Merel;
- Loohuis, Loes Olde;
- Teunissen, Charlotte E.;
- Ophoff, Roel;
- Tijms, Betty;
- van der Lee, Sven J;
- Visser, Pieter Jelle;
- van der Flier, Wiesje M.;
- Ramesh, Naren
Publication type:
Article
TREM2 Burden associates solely with Alzheimer's Disease, and decreases the Chance to become a Centenarian.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078234
By:
- Dijkstra, Janna I.R.;
- Vermunt, Lisa;
- Biessels, Geert Jan;
- Braber, Anouk;
- Claassen, Jurgen A.H.R.;
- De Deyn, Peter Paul;
- Ghanbari, Mohsen;
- Huisman, Martijn;
- Hulsman, Marc;
- Ramakers, Inez H.G.B.;
- Reinders, Marcel J. T.;
- Seelaar, Harro;
- Tesi, Niccoló;
- Visser, Pieter Jelle;
- van der Flier, Wiesje M.;
- Teunissen, Charlotte E.;
- Holstege, Henne;
- Van Der Lee, Sven J
Publication type:
Article
Identifying Cognitive Resilience Related Genes Among Genetic Risk Loci of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077781
By:
- Carrigan, Maria;
- Van der Lee, Sven J;
- van Loenhoud, Anna C.;
- Bocancea, Diana I.;
- Groot, Colin;
- Barkhof, Frederik;
- Krugers, Harm J.;
- Lucassen, Paul J.;
- van der Flier, Wiesje M.;
- Ossenkoppele, Rik
Publication type:
Article
Cognitively Healthy Centenarians are genetically protected against Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076095
By:
- Tesi, Niccoló;
- Van Der Lee, Sven J;
- Hulsman, Marc;
- van Schoor, Natasja;
- Huisman, Martijn;
- Pijnenburg, Yolande A. L.;
- Flier, Wiesje M.;
- Reinders, Marcel JT;
- Holstege, Henne
Publication type:
Article
Rare copy number variation in the GR@ACE/DEGESCO dementia dataset of spanish population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074012
By:
- de Rojas, Itziar;
- García‐Ribas, Guillermo;
- Sanchez‐Juan, Pascual;
- Perez‐Tur, Jordi;
- Pastor, Pau;
- Bullido, María J.;
- Álvarez‐Martínez, Victoria;
- Real, Luis Miguel;
- Mir, Pablo;
- Piñol‐Ripoll, Gerard;
- García‐Alberca, Jose María;
- Medina, Miguel;
- Sáez, María Eugenia;
- Carracedo, Angel;
- Tárraga, Lluís;
- Boada, Mercè;
- Van Der Lee, Sven J;
- Ruiz, Agustin
Publication type:
Article
Shorter disease duration in females with sporadic frontotemporal dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067557
By:
- de Boer, Sterre C.M.;
- Riedl, Lina;
- Van der lee, Sven J;
- Otto, Markus;
- Anderl‐Straub, Sarah;
- Landin‐Romero, Ramon;
- Sorrentino, Federica;
- Fieldhouse, Jay L.P.;
- Reus, Lianne M.;
- Halliday, Glenda M;
- Galimberti, Daniela;
- Diehl‐Schmid, Janine;
- Ducharme, Simon;
- Piguet, Olivier;
- Pijnenburg, Yolande A.L.
Publication type:
Article
Genetic insights of all‐cause and vascular dementia through genome‐wide association studies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067165
By:
- Fongang, Bernard;
- Sargurupremraj, Muralidharan;
- Jian, Xueqiu;
- Mishra, Aniket;
- Bis, Joshua C;
- Fan, Kang‐Hsien;
- Li, Gloria;
- Yang, Jingyun;
- Hilal, Saima;
- Knol, Maria J.;
- Concas, Maria Pina;
- Girotto, Giorgia;
- Riaz, Moeen;
- Guðjónsson, Alexander;
- Lacaze, Paul;
- Naj, Adam C.;
- Van Der Lee, Sven J.;
- Skrobot, Olivia Anna;
- Gudnason, Vilmundur;
- Lopez, Oscar L.
Publication type:
Article
Differences in sex distribution between genetic and sporadic FTD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052836
By:
- de Boer, Sterre C.M.;
- Van Der Lee, Sven J;
- Diehl‐Schmid, Janine;
- Riedl, Lina;
- Piguet, Olivier;
- Halliday, Glenda M;
- Galimberti, Daniela;
- Sorrentino, Federica;
- Ducharme, Simon;
- Fieldhouse, Jay L.P.;
- Reus, Lianne M.;
- Pijnenburg, Yolande A.L.
Publication type:
Article
Pathway‐specific polygenic risk score of AD‐associated genetic variants associated with AD risk, resilience against AD, and progression to AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053500
By:
- Tesi, Niccoló;
- Van Der Lee, Sven J;
- Hulsman, Marc;
- Jansen, Iris E.;
- Stringa, Najada;
- van Schoor, Natasja;
- Huisman, Martijn;
- Scheltens, Philip;
- Reinders, Marcel JT;
- van der Flier, Wiesje M;
- Holstege, Henne
Publication type:
Article
The majority of the patients with a monogenic predisposition for dementia did not fulfill current criteria for genetic testing.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.052075
By:
- Van Der Lee, Sven J;
- Hulsman, Marc;
- van Spaendonk, Rosalina M.L.;
- Cohn‐Hokke, Petra E;
- van der Flier, Wiesje M;
- Holstege, Henne;
- Scheltens, Philip
Publication type:
Article
Alzheimer's disease genetic risk variants show brain cell type‐specific associations with protein levels in cerebrospinal fluid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.049531
By:
- Reus, Lianne M.;
- Van Der Lee, Sven J;
- Teunissen, Charlotte E.;
- Gobom, Johan;
- Vos, Stephanie J. B.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bertram, Lars;
- Visser, Pieter Jelle;
- Tijms, Betty M.
Publication type:
Article
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participants.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 10, p. 1663, doi. 10.1002/alz.12333
By:
- Damotte, Vincent;
- van der Lee, Sven J.;
- Chouraki, Vincent;
- Grenier‐Boley, Benjamin;
- Simino, Jeannette;
- Adams, Hieab;
- Tosto, Giuseppe;
- White, Charles;
- Terzikhan, Natalie;
- Cruchaga, Carlos;
- Knol, Maria J.;
- Li, Shuo;
- Schraen, Susanna;
- Grove, Megan L.;
- Satizabal, Claudia;
- Amin, Najaf;
- Berr, Claudine;
- Younkin, Steven;
- Gottesman, Rebecca F.;
- Buée, Luc
Publication type:
Article
Attitudes towards genetic susceptibility testing for Alzheimer's disease dementia in cognitively normal adults: A survey study: Developing topics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047393
By:
- Masselink, Larissa A;
- Visser, Leonie NC;
- Cleutjens, Solange;
- van der Lee, Sven J;
- van der Schaar, Jetske;
- Scheltens, Philip;
- van Der Flier, Wiesje;
- Zwan, Marissa D
Publication type:
Article
Genome‐wide meta‐analysis of late‐onset Alzheimer's disease using rare variant imputation in 65,602 subjects identifies risk loci with roles in memory, neurodevelopment, and cardiometabolic traits: The international genomics of Alzheimer's project (IGAP): Genetics: Genetics and omics of AD II
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044193
By:
- Naj, Adam C.;
- Sha, Jin;
- Zhao, Yi;
- Leonenko, Ganna;
- Jian, Xueqiu;
- Grenier‐Boley, Benjamin;
- Dalmasso, Maria Carolina;
- van der Lee, Sven J.;
- Sims, Rebecca;
- Chouraki, Vincent;
- Bis, Josh C.;
- Kuzma, Amanda B.;
- Kunkle, Brian W.;
- Karamujić‐Čomić, Hata;
- Pitsillides, Achilleas N.;
- Xia, Rui;
- Fulton‐Howard, Brian;
- Holmans, Peter;
- Dupuis, Josée;
- Wang, Li‐San
Publication type:
Article
BDNF‐Met polymorphism on top of amyloid pathology predisposes for faster cognitive decline in cognitively normal elderly: The SCIENCe Project: Genetics/genetic factors of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042728
By:
- van den Bosch, Karlijn Antoinette;
- Verberk, Inge M.W.;
- Ebenau, Jarith;
- van der Lee, Sven J.;
- Jansen, Iris E.;
- Prins, Niels D.;
- Scheltens, Philip;
- Teunissen, Charlotte E.;
- van Der Flier, Wiesje
Publication type:
Article
Immune response and endocytosis pathways are associated with the resilience against Alzheimer's disease: Genetics: Molecular genetics of AD and ADRD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042614
By:
- Tesi, Niccoló;
- Van Der Lee, Sven J.;
- Hulsman, Marc;
- Jansen, Iris E.;
- Stringa, Najada;
- van Schoor, Natasja;
- Scheltens, Philip;
- van Der Flier, Wiesje;
- Huisman, Martijn;
- Reinders, Marcel J.T.;
- Holstege, Henne
Publication type:
Article
A polygenic risk score for Alzheimer's disease determines the risk of incident dementia in APOE ɛ4 negative individuals over the age of 95: A population‐based cohort study: Genetics/genetic factors of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042452
By:
- Najar, Jenna;
- Joas, Erik;
- Van Der Lee, Sven J.;
- Wetterberg, Hanna;
- Guerreiro, Rita;
- Bras, Jose;
- Hardy, John A.;
- Waern, Margda;
- Kern, Silke;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Skoog, Ingmar;
- Zettergren, Anna
Publication type:
Article
Polygenic risk score for Alzheimer's disease is related to amyloid positivity in subjective cognitive decline: The SCIENCe project: Neuroimaging: Imaging genetics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042116
By:
- van der Lee, Sven J.;
- Ebenau, Jarith L.;
- Jansen, Iris E.;
- Verberk, Inge M.W.;
- Scheltens, Philip;
- Teunissen, Charlotte E.;
- Barkhof, Frederik;
- Reinders, Marcel J.T.;
- Van Berckel, Bart N.M.;
- Holstege, Henne;
- van Der Flier, Wiesje
Publication type:
Article
Novel genetic effects on amyloid and tau protein levels in cerebrospinal fluid: Towards a better knowledge of the genetics of Alzheimer's disease, the European Alzheimer Disease Biobank (EADB) Consortium.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037973
By:
- Jansen, Iris E.;
- Van Der Lee, Sven J.;
- Bellenguez, Céline;
- Grenier‐Boley, Benjamin;
- de Rojas, Itziar;
- Zettergren, Anna;
- Kleineidam, Luca
Publication type:
Article
O2‐10‐06: GENOME‐WIDE META‐ANALYSIS OF LATE‐ONSET ALZHEIMER'S DISEASE USING RARE VARIANT IMPUTATION IN 64,859 SUBJECTS IDENTIFIES RISK LOCI WITH ROLES IN INNATE IMMUNITY AND CARDIOVASCULAR TRAITS: THE INTERNATIONAL GENOMICS OF ALZHEIMER'S PROJECT (IGAP)
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P566, doi. 10.1016/j.jalz.2019.06.4510
By:
- Naj, Adam;
- Sha, Jin;
- Leonenko, Ganna;
- Chen, Yuning;
- Chouraki, Vincent;
- Leber, Markus;
- Sims, Rebecca;
- Grenier-Boley, Benjamin;
- Bis, Joshua C.;
- Zhao, Yi;
- Kuzma, Amanda B.;
- Kunkle, Brian W.;
- Karamujić-Čomić, Hata;
- Van Der Lee, Sven J.;
- Bellenguez, Celine;
- Frizzati, Aura;
- Holmans, Peter;
- Dupuis, Josée;
- Wang, Li-San;
- Farrer, Lindsay A.
Publication type:
Article
O5‐04‐01: A RARE GENETIC VARIANT IN THE PLCG2 GENE IS ASSOCIATED WITH A REDUCED RISK OF ALL MAJOR TYPES OF DEMENTIA AND AN INCREASED RISK TO REACH AN EXTREMELY OLD AGE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1648, doi. 10.1016/j.jalz.2018.06.3013
By:
- Van der Lee, Sven J.;
- Jansen, Iris E.;
- Pletnikova, Olga;
- Blauwendraat, Cornelis;
- Hulsman, Marc;
- Dalmasso, Maria Carolina;
- Kawalia, Amit;
- Ramirez, Alfredo;
- Van der Flier, Wiesje M.;
- Scheltens, Philip;
- Reinders, Marcel JT.;
- Hernandez, Isabel;
- Lleó, Alberto;
- Fortea, Juan;
- Stringa, Najada;
- Ruiz, Agustín Ruiz;
- Illán-Gala, Ignacio;
- Morenas-Rodríguez, Estrella;
- Clarimon, Jordi;
- Lage, Carmen
Publication type:
Article
P4‐240: STOP‐GAIN VARIANT IN MICROGLIA‐EXPRESSED GENE GMIP IS ASSOCIATED WITH EARLY‐ONSET ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1534, doi. 10.1016/j.jalz.2018.07.061
By:
- Khan, Raiyan R.;
- Altmann, Andre;
- Napolioni, Valerio;
- Kim, Yongha;
- Guerreiro, Rita;
- Bras, Jose T.;
- Carmona, Susana;
- Pereira, Miguel;
- Santana, Isabel;
- Hardy, John;
- Mead, Simon;
- Cruchaga, Carlos;
- Fernandez, Maria Victoria;
- Holstege, Henne;
- Van der Flier, Wiesje M.;
- Hulsman, Marc;
- Van der Lee, Sven J.;
- Chen, Yuning;
- Bis, Joshua C.;
- Launer, Lenore J.
Publication type:
Article
P4‐158: THE ASSOCIATION OF VASCULAR DISORDERS WITH INCIDENT DEMENTIA AND MORTALITY IN DIFFERENT AGE GROUPS IN A PRIMARY CARE DATABASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1499, doi. 10.1016/j.jalz.2018.06.2563
By:
- Legdeur, Nienke;
- Van der Lee, Sven J.;
- de Wilde, Marcel;
- Van Der Lei, Johan;
- Maier, Andrea B.;
- Visser, Pieter Jelle
Publication type:
Article
P4‐038: IS SORL1 AN AUTOSOMAL DOMINANT ALZHEIMER GENE?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1447, doi. 10.1016/j.jalz.2018.06.2440
By:
- Van der Lee, Sven J.;
- Minderhoud, Crista;
- van Spaendonk, Rosalina;
- Meijers-Heijboer, Hanne;
- Van der Flier, Wiesje M.;
- Scheltens, Philip;
- Holstege, Henne
Publication type:
Article
P2‐134: THE ADDED VALUE OF EXTREME PHENOTYPES IN ALZHEIMER'S DISEASE CASE‐CONTROL STUDIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P719, doi. 10.1016/j.jalz.2018.06.820
By:
- Tesi, Niccoló;
- Van der Lee, Sven J.;
- Hulsman, Marc;
- Jansen, Iris E.;
- Stringa, Najada;
- van Schoor, Natasja;
- Meijers-Heijboer, Hanne;
- Huisman, Martijn;
- Scheltens, Philip;
- Reinders, Marcel JT.;
- Van der Flier, Wiesje M.;
- Holstege, Henne
Publication type:
Article
Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 7, p. 848, doi. 10.1016/j.jalz.2018.01.005
By:
- Ahmad, Shahzad;
- Bannister, Christian;
- van der Lee, Sven J.;
- Vojinovic, Dina;
- Adams, Hieab H.H.;
- Ramirez, Alfredo;
- Escott‐Price, Valentina;
- Sims, Rebecca;
- Baker, Emily;
- Williams, Julie;
- Holmans, Peter;
- Vernooij, Meike W.;
- Ikram, M. Arfan;
- Amin, Najaf;
- van Duijn, Cornelia M.
Publication type:
Article
Association of branched‐chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 6, p. 723, doi. 10.1016/j.jalz.2018.01.003
By:
- Tynkkynen, Juho;
- Chouraki, Vincent;
- van der Lee, Sven J.;
- Hernesniemi, Jussi;
- Yang, Qiong;
- Li, Shuo;
- Beiser, Alexa;
- Larson, Martin G.;
- Sääksjärvi, Katri;
- Shipley, Martin J.;
- Singh‐Manoux, Archana;
- Gerszten, Robert E.;
- Wang, Thomas J.;
- Havulinna, Aki S.;
- Würtz, Peter;
- Fischer, Krista;
- Demirkan, Ayse;
- Ikram, M. Arfan;
- Amin, Najaf;
- Lehtimäki, Terho
Publication type:
Article
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 6, p. 707, doi. 10.1016/j.jalz.2017.11.012
By:
- van der Lee, Sven J.;
- Teunissen, Charlotte E.;
- Pool, René;
- Shipley, Martin J.;
- Teumer, Alexander;
- Chouraki, Vincent;
- Melo van Lent, Debora;
- Tynkkynen, Juho;
- Fischer, Krista;
- Hernesniemi, Jussi;
- Haller, Toomas;
- Singh‐Manoux, Archana;
- Verhoeven, Aswin;
- Willemsen, Gonneke;
- de Leeuw, Francisca A.;
- Wagner, Holger;
- van Dongen, Jenny;
- Hertel, Johannes;
- Budde, Kathrin;
- Willems van Dijk, Ko
Publication type:
Article
Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score.
Published in:
BMC Neurology, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12883-022-02925-6
By:
- Tomassen, Jori;
- den Braber, Anouk;
- van der Lee, Sven J.;
- Reus, Lianne M.;
- Konijnenberg, Elles;
- Carter, Stephen F.;
- Yaqub, Maqsood;
- van Berckel, Bart N.M.;
- Collij, Lyduine E.;
- Boomsma, Dorret I.;
- de Geus, Eco J.C.;
- Scheltens, Philip;
- Herholz, Karl;
- Tijms, Betty M.;
- Visser, Pieter Jelle
Publication type:
Article
Immune response and endocytosis pathways are associated with the resilience against Alzheimer's disease.
Published in:
Translational Psychiatry, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41398-020-01018-7
By:
- Tesi, Niccolò;
- van der Lee, Sven J.;
- Hulsman, Marc;
- Jansen, Iris E.;
- Stringa, Najada;
- van Schoor, Natasja M.;
- Scheltens, Philip;
- van der Flier, Wiesje M.;
- Huisman, Martijn;
- Reinders, Marcel J. T.;
- Holstege, Henne
Publication type:
Article
The association of vascular disorders with incident dementia in different age groups.
Published in:
Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0496-x
By:
- Legdeur, Nienke;
- van der Lee, Sven J.;
- de Wilde, Marcel;
- van der Lei, Johan;
- Muller, Majon;
- Maier, Andrea B.;
- Visser, Pieter Jelle
Publication type:
Article
Gray matter heritability in family-based and population-based studies using voxel-based morphometry.
Published in:
Human Brain Mapping, 2017, v. 38, n. 5, p. 2408, doi. 10.1002/hbm.23528
By:
- van der Lee, Sven J.;
- Roshchupkin, Gennady V.;
- Adams, Hieab H. H.;
- Schmidt, Helena;
- Hofer, Edith;
- Saba, Yasaman;
- Schmidt, Reinhold;
- Hofman, Albert;
- Amin, Najaf;
- van Duijn, Cornelia M.;
- Vernooij, Meike W.;
- Ikram, M. Arfan;
- Niessen, Wiro J.
Publication type:
Article
ALZHEIMER'S DISEASE SEQUENCING PROJECT: CASE-CONTROL ANALYSES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P570, doi. 10.1016/j.jalz.2017.07.186
By:
- Bis, Joshua C.;
- Jian, Xueqiu;
- Kunkle, Brian W.;
- Hamilton, Kara L.;
- Bush, William S.;
- Salerno, William;
- Lancour, Dan;
- Ma, Yiyi;
- Chen, Yuning;
- Destefano, Anita L.;
- Dupuis, Josée;
- Farrell, John;
- Zhao, Yi;
- Qu, Liming;
- Bellenguez, Celine;
- Lambert, Jean-Charles;
- van der Lee, Sven J.;
- van Duijn, Cornelia M.;
- Boerwinkle, Eric;
- Martin, Eden R.
Publication type:
Article

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