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Development and performance of the c4c national clinical trial networks for optimizing pediatric trial facilitation.
- Published in:
- Frontiers in Pediatrics, 2024, p. 1, doi. 10.3389/fped.2023.1302272
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- Publication type:
- Article
Assessment of self-perceived knowledge of key clinical pharmacology concepts and educational needs among European Paediatric Intensive Care Units: an ESPNIC survey.
- Published in:
- Intensive Care Medicine - Paediatric & Neonatal, 2024, v. 2, n. 1, p. 1, doi. 10.1007/s44253-024-00044-3
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- Publication type:
- Article
Perceived barriers and facilitators for model-informed dosing in pregnancy: a qualitative study across healthcare practitioners and pregnant women.
- Published in:
- BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03450-8
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- Publication type:
- Article
Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial.
- Published in:
- Critical Care, 2024, v. 28, n. 1, p. 1, doi. 10.1186/s13054-024-04905-3
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- Publication type:
- Article
Maximum likelihood estimation of renal transporter ontogeny profiles for pediatric PBPK modeling.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 4, p. 576, doi. 10.1002/psp4.13102
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- Publication type:
- Article
Towards More Robust Evaluation of the Predictive Performance of Physiologically Based Pharmacokinetic Models: Using Confidence Intervals to Support Use of Model-Informed Dosing in Clinical Care.
- Published in:
- Clinical Pharmacokinetics, 2024, v. 63, n. 3, p. 343, doi. 10.1007/s40262-023-01326-3
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- Publication type:
- Article
Mental Health of School-Aged Children Treated with Propranolol or Atenolol for Infantile Hemangioma and Their Parents.
- Published in:
- Dermatology (10188665), 2024, v. 240, n. 2, p. 216, doi. 10.1159/000536144
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- Publication type:
- Article
Development and performance of the c4c national clinical trial networks for optimizing pediatric trial facilitation.
- Published in:
- Frontiers in Pediatrics, 2024, p. 1, doi. 10.3389/fped.2023.1302272
- By:
- Publication type:
- Article
Pain during the first year after scoliosis surgery in adolescents, an exploratory, prospective cohort study.
- Published in:
- Frontiers in Pediatrics, 2024, p. 01, doi. 10.3389/fped.2024.1293588
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- Publication type:
- Article
Pragmatic physiologically-based pharmacokinetic modeling to support clinical implementation of optimized gentamicin dosing in term neonates and infants: proof-of-concept.
- Published in:
- Frontiers in Pediatrics, 2023, p. 1, doi. 10.3389/fped.2023.1288376
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- Publication type:
- Article
Physiologically‐Based Pharmacokinetic Modeling for Drug Dosing in Pediatric Patients: A Tutorial for a Pragmatic Approach in Clinical Care.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 5, p. 960, doi. 10.1002/cpt.3023
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- Publication type:
- Article
Dose rationale for gabapentin and tramadol in pediatric patients with chronic pain.
- Published in:
- Pharmacology Research & Perspectives, 2023, v. 11, n. 5, p. 1, doi. 10.1002/prp2.1138
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- Publication type:
- Article
Guiding future paediatric drug studies based on existing pharmacokinetic and efficacy data: Cardiovascular drugs as a proof of concept.
- Published in:
- British Journal of Clinical Pharmacology, 2023, v. 89, n. 9, p. 2888, doi. 10.1111/bcp.15781
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- Publication type:
- Article
Correction to: Long-term neurocognitive functioning of children treated with propranolol or atenolol for infantile hemangioma.
- Published in:
- European Journal of Pediatrics, 2023, v. 182, n. 9, p. 4285, doi. 10.1007/s00431-023-05059-0
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- Publication type:
- Article
Optimizing expert and patient input in pediatric trial design: Lessons learned and recommendations from a collaboration between conect4children and European Patient‐CEntric ClinicAl TRial PLatforms.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 8, p. 1458, doi. 10.1111/cts.13547
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- Publication type:
- Article
Global Association of the COVID-19 Pandemic With Pediatric Clinical Trial Publication.
- Published in:
- JAMA Network Open, 2023, v. 6, n. 7, p. e2326313, doi. 10.1001/jamanetworkopen.2023.26313
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- Publication type:
- Article
Neonatal Drug Formularies—A Global Scope.
- Published in:
- Children, 2023, v. 10, n. 5, p. 848, doi. 10.3390/children10050848
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- Publication type:
- Article
Development of Best Evidence Dosing Recommendations for Term and Preterm Neonates (NeoDose Project).
- Published in:
- Neonatology (16617800), 2023, v. 120, n. 2, p. 196, doi. 10.1159/000528012
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- Publication type:
- Article
Lamivudine and Emtricitabine Dosing Proposal for Children with HIV and Chronic Kidney Disease, Supported by Physiologically Based Pharmacokinetic Modelling.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 5, p. 1424, doi. 10.3390/pharmaceutics15051424
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- Publication type:
- Article
Glomerular filtration rate in critically ill neonates and children: creatinine-based estimations versus iohexol-based measurements.
- Published in:
- Pediatric Nephrology, 2023, v. 38, n. 4, p. 1087, doi. 10.1007/s00467-022-05651-w
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- Publication type:
- Article
Clinical, methodology, and patient/carer expert advice in pediatric drug development by conect4children.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 3, p. 478, doi. 10.1111/cts.13459
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- Publication type:
- Article
Long-term neurocognitive functioning of children treated with propranolol or atenolol for infantile hemangioma.
- Published in:
- European Journal of Pediatrics, 2023, v. 182, n. 2, p. 757, doi. 10.1007/s00431-022-04674-7
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- Publication type:
- Article
Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers.
- Published in:
- Acta Dermato-Venereologica, 2023, v. 103, p. 1, doi. 10.2340/actadv.v103.5286
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- Publication type:
- Article
Proenkephalin A as a marker for glomerular filtration rate in critically ill children: validation against gold standard iohexol GFR measurements.
- Published in:
- Clinical Chemistry & Laboratory Medicine, 2023, v. 61, n. 1, p. 104, doi. 10.1515/cclm-2022-0545
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- Publication type:
- Article
Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population.
- Published in:
- Pediatric Drugs, 2023, v. 25, n. 1, p. 5, doi. 10.1007/s40272-022-00535-w
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- Publication type:
- Article
Innovative methodologies in paediatric drug development: A conect4children (c4c) special issue.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 4962, doi. 10.1111/bcp.15355
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- Publication type:
- Article
Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 4965, doi. 10.1111/bcp.14958
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- Publication type:
- Article
General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 4985, doi. 10.1111/bcp.15571
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- Publication type:
- Article
How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 5017, doi. 10.1111/bcp.15216
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- Publication type:
- Article
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.
- Published in:
- Clinical Pharmacokinetics, 2022, v. 61, n. 12, p. 1705, doi. 10.1007/s40262-022-01181-8
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- Publication type:
- Article
Off‐Label, but on‐Evidence? A Review of the Level of Evidence for Pediatric Pharmacotherapy.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1243, doi. 10.1002/cpt.2736
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- Publication type:
- Article
Correspondence to: Reliability of glomerular filtration rate estimating formulas compared to iohexol plasma clearance in critically ill children.
- Published in:
- 2022
- By:
- Publication type:
- Letter to the Editor
Innovative approaches and recent advances in the study of ontogeny of drug metabolism and transport.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 10, p. 4285, doi. 10.1111/bcp.14534
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- Publication type:
- Article
A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 10, p. 2392, doi. 10.1111/cts.13368
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- Publication type:
- Article
Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children.
- Published in:
- 2022
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- Publication type:
- journal article
Enalapril and Enalaprilat Pharmacokinetics in Children with Heart Failure Due to Dilated Cardiomyopathy and Congestive Heart Failure after Administration of an Orodispersible Enalapril Minitablet (LENA-Studies).
- Published in:
- Pharmaceutics, 2022, v. 14, n. 6, p. 1163, doi. 10.3390/pharmaceutics14061163
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- Publication type:
- Article
Best Evidence-Based Dosing Recommendations for Dexmedetomidine for Premedication and Procedural Sedation in Pediatrics: Outcome of a Risk-Benefit Analysis By the Dutch Pediatric Formulary.
- Published in:
- Pediatric Drugs, 2022, v. 24, n. 3, p. 247, doi. 10.1007/s40272-022-00498-y
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- Publication type:
- Article
Aesthetic Outcome of Propranolol vs Atenolol Treatment of Children with Infantile Haemangioma.
- Published in:
- Acta Dermato-Venereologica, 2022, v. 102, p. 1, doi. 10.2340/actadv.v102.2021
- By:
- Publication type:
- Article
Quantifying the Pharmacodynamics of Morphine in the Treatment of Postoperative Pain in Preverbal Children.
- Published in:
- Journal of Clinical Pharmacology, 2022, v. 62, n. 1, p. 99, doi. 10.1002/jcph.1952
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- Publication type:
- Article
Current Ceftriaxone Dose Recommendations are Adequate for Most Critically Ill Children: Results of a Population Pharmacokinetic Modeling and Simulation Study.
- Published in:
- Clinical Pharmacokinetics, 2021, v. 60, n. 10, p. 1361, doi. 10.1007/s40262-021-01035-9
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- Publication type:
- Article
Benefit‐Risk Assessment of Off‐Label Drug Use in Children: The Bravo Framework.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 952, doi. 10.1002/cpt.2336
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- Publication type:
- Article
Midazolam Infusion and Disease Severity Affect the Level of Sedation in Children: A Parametric Time-to-Event Analysis.
- Published in:
- Pharmaceutical Research, 2021, v. 38, n. 10, p. 1711, doi. 10.1007/s11095-021-03113-w
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- Publication type:
- Article
Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling.
- Published in:
- Archives of Toxicology, 2021, v. 95, n. 9, p. 3015, doi. 10.1007/s00204-021-03115-y
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- Publication type:
- Article
Assessing causality by means of the Naranjo scale in a paediatric patient with life threatening respiratory failure after alemtuzumab administration: a case report.
- Published in:
- 2021
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- Publication type:
- journal article
Rapid Implementation of Model-Based Dosing Recommendations During the Coronavirus Disease 2019 Pandemic.
- Published in:
- 2021
- By:
- Publication type:
- Letter
Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children.
- Published in:
- PLoS Computational Biology, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.pcbi.1008786
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- Publication type:
- Article
The conect4children (c4c) Consortium: Potential for Improving European Clinical Research into Medicines for Children.
- Published in:
- Pharmaceutical Medicine, 2021, v. 35, n. 2, p. 71, doi. 10.1007/s40290-020-00373-6
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- Publication type:
- Article
Pharmacological and Parenteral Nutrition-Based Interventions in Microvillus Inclusion Disease.
- Published in:
- Journal of Clinical Medicine, 2021, v. 10, n. 1, p. 22, doi. 10.3390/jcm10010022
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- Publication type:
- Article
A New Framework to Implement Model-Informed Dosing in Clinical Guidelines: Piperacillin and Amikacin as Proof of Concept.
- Published in:
- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.592204
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- Publication type:
- Article
Diagnosis and Treatment of Chronic Neuropathic and Mixed Pain in Children and Adolescents: Results of a Survey Study amongst Practitioners.
- Published in:
- Children, 2020, v. 7, n. 11, p. 1, doi. 10.3390/children7110208
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- Publication type:
- Article