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Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27854-9
By:
- Wu, Yue;
- Cui, Zhenling;
- Huang, Yen-Hua;
- de Veer, Simon J.;
- Aralov, Andrey V.;
- Guo, Zhong;
- Moradi, Shayli V.;
- Hinton, Alexandra O.;
- Deuis, Jennifer R.;
- Guo, Shaodong;
- Chen, Kai-En;
- Collins, Brett M.;
- Vetter, Irina;
- Herzig, Volker;
- Jones, Alun;
- Cooper, Matthew A.;
- King, Glenn F.;
- Craik, David J.;
- Alexandrov, Kirill;
- Mureev, Sergey
Publication type:
Article
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Published in:
Biochemical Journal, 2015, v. 469, n. 2, p. 243, doi. 10.1042/BJ20150412
By:
- de Veer, Simon J.;
- Swedberg, Joakim E.;
- Akcan, Muharrem;
- Rosengren, K. Johan;
- Brattsand, Maria;
- Craik, David J.;
- Harris, Jonathan M.
Publication type:
Article
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27854-9
By:
- Wu, Yue;
- Cui, Zhenling;
- Huang, Yen-Hua;
- de Veer, Simon J.;
- Aralov, Andrey V.;
- Guo, Zhong;
- Moradi, Shayli V.;
- Hinton, Alexandra O.;
- Deuis, Jennifer R.;
- Guo, Shaodong;
- Chen, Kai-En;
- Collins, Brett M.;
- Vetter, Irina;
- Herzig, Volker;
- Jones, Alun;
- Cooper, Matthew A.;
- King, Glenn F.;
- Craik, David J.;
- Alexandrov, Kirill;
- Mureev, Sergey
Publication type:
Article
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.
Published in:
Scientific Reports, 2016, p. 35385, doi. 10.1038/srep35385
By:
- Riley, Blake T.;
- Ilyichova, Olga;
- Costa, Mauricio G. S.;
- Porebski, Benjamin T.;
- de Veer, Simon J.;
- Swedberg, Joakim E.;
- Kass, Itamar;
- Harris, Jonathan M.;
- Hoke, David E.;
- Buckle, Ashley M.
Publication type:
Article
Mastering the Canonical Loop of Serine Protease Inhibitors: Enhancing Potency by Optimising the Internal Hydrogen Bond Network.
Published in:
PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019302
By:
- Swedberg, Joakim E.;
- de Veer, Simon J.;
- Sit, Kei C.;
- Reboul, Cyril F.;
- Buckle, Ashley M.;
- Harris, Jonathan M.
Publication type:
Article
Characterising the Subsite Specificity of Urokinase‐Type Plasminogen Activator and Tissue‐Type Plasminogen Activator using a Sequence‐Defined Peptide Aldehyde Library.
Published in:
ChemBioChem, 2019, v. 20, n. 1, p. 46, doi. 10.1002/cbic.201800395
By:
- Li, Choi Yi;
- de Veer, Simon J.;
- Law, Ruby H. P.;
- Whisstock, James C.;
- Craik, David J.;
- Swedberg, Joakim E.
Publication type:
Article
Cystine Knot Peptides with Tuneable Activity and Mechanism.
Published in:
Angewandte Chemie, 2022, v. 134, n. 19, p. 1, doi. 10.1002/ange.202200951
By:
- Li, Choi Yi;
- Rehm, Fabian B. H.;
- Yap, Kuok;
- Zdenek, Christina N.;
- Harding, Maxim D.;
- Fry, Bryan G.;
- Durek, Thomas;
- Craik, David J.;
- de Veer, Simon J.
Publication type:
Article
Enzymatic C‐to‐C Protein Ligation.
Published in:
Angewandte Chemie, 2022, v. 134, n. 11, p. 1, doi. 10.1002/ange.202116672
By:
- Rehm, Fabian B. H.;
- Tyler, Tristan J.;
- de Veer, Simon J.;
- Craik, David J.;
- Durek, Thomas
Publication type:
Article
Cystine Knot Peptides with Tuneable Activity and Mechanism.
Published in:
Angewandte Chemie International Edition, 2022, v. 61, n. 19, p. 1, doi. 10.1002/anie.202200951
By:
- Li, Choi Yi;
- Rehm, Fabian B. H.;
- Yap, Kuok;
- Zdenek, Christina N.;
- Harding, Maxim D.;
- Fry, Bryan G.;
- Durek, Thomas;
- Craik, David J.;
- de Veer, Simon J.
Publication type:
Article
Enzymatic C‐to‐C Protein Ligation.
Published in:
Angewandte Chemie International Edition, 2022, v. 61, n. 11, p. 1, doi. 10.1002/anie.202116672
By:
- Rehm, Fabian B. H.;
- Tyler, Tristan J.;
- de Veer, Simon J.;
- Craik, David J.;
- Durek, Thomas
Publication type:
Article
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases.
Published in:
Nature Protocols, 2021, v. 16, n. 3, p. 1740, doi. 10.1038/s41596-020-00483-0
By:
- Yap, Kuok;
- Du, Junqiao;
- Rehm, Fabian B. H.;
- Tang, Shyn Ric;
- Zhou, Yan;
- Xie, Jing;
- Wang, Conan K.;
- de Veer, Simon J.;
- Lua, Linda H. L.;
- Durek, Thomas;
- Craik, David J.
Publication type:
Article
Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif.
Published in:
PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210842
By:
- Chen, Xingchen;
- Riley, Blake T.;
- de Veer, Simon J.;
- Hoke, David E.;
- Van Haeften, Jessica;
- Leahy, Darren;
- Swedberg, Joakim E.;
- Brattsand, Maria;
- Hartfield, Perry J.;
- Buckle, Ashley M.;
- Harris, Jonathan M.
Publication type:
Article
Display Technologies for Expanding the Pharmaceutical Applications of Cyclotides.
Published in:
Israel Journal of Chemistry, 2024, v. 64, n. 8/9, p. 1, doi. 10.1002/ijch.202400010
By:
- Xie, Jing;
- Kan, Meng‐Wei;
- de Veer, Simon J.;
- Wang, Conan;
- Craik, David J.
Publication type:
Article
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.
Published in:
Biological Chemistry, 2012, v. 393, n. 5, p. 331, doi. 10.1515/bc-2011-250
By:
- de Veer, Simon J.;
- Swedberg, Joakim E.;
- Parker, Edward A.;
- Harris, Jonathan M.
Publication type:
Article
Natural and engineered kallikrein inhibitors: an emerging pharmacopoeia.
Published in:
Biological Chemistry, 2010, v. 391, n. 4, p. 357, doi. 10.1515/BC.2010.037
By:
- Swedberg, Joakim E.;
- de Veer, Simon J.;
- Harris, Jonathan M.
Publication type:
Article

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