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Primary SARS-CoV-2 variant of concern infections elicit broad antibody Fc-mediated effector functions and memory B cell responses.
Published in:
PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012453
By:
- van der Straten, Karlijn;
- Guerra, Denise;
- Kerster, Gius;
- Claireaux, Mathieu;
- Grobben, Marloes;
- Schriek, Angela I.;
- Boyd, Anders;
- van Rijswijk, Jacqueline;
- Tejjani, Khadija;
- Eggink, Dirk;
- Beaumont, Tim;
- de Taeye, Steven W.;
- de Bree, Godelieve J.;
- Sanders, Rogier W.;
- van Gils, Marit J.
Publication type:
Article
Anti-HIV-1 Nanobody-IgG1 Constructs With Improved Neutralization Potency and the Ability to Mediate Fc Effector Functions.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.893648
By:
- Schriek, Angela I.;
- van Haaren, Marlies M.;
- Poniman, Meliawati;
- Dekkers, Gillian;
- Bentlage, Arthur E. H.;
- Grobben, Marloes;
- Vidarsson, Gestur;
- Sanders, Rogier W.;
- Verrips, Theo;
- Geijtenbeek, Teunis B. H.;
- Heukers, Raimond;
- Kootstra, Neeltje A.;
- de Taeye, Steven W.;
- van Gils, Marit J.
Publication type:
Article
Variable Domain N-linked glycans acquired During antigen-specific immune responses can contribute to immunoglobulin g antibody stability.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00740
By:
- van de Bovenkamp, Fleur S.;
- Derksen, Ninotska I. L.;
- van Breemen, Mariëlle J.;
- de Taeye, Steven W.;
- Ooijevaar-de Heer, Pleuni;
- Sanders, Rogier W.;
- Rispens, Theo
Publication type:
Article
FcγR Binding and ADCC Activity of Human IgG Allotypes.
Published in:
Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00740
By:
- de Taeye, Steven W.;
- Bentlage, Arthur E. H.;
- Mebius, Mirjam M.;
- Meesters, Joyce I.;
- Lissenberg-Thunnissen, Suzanne;
- Falck, David;
- Sénard, Thomas;
- Salehi, Nima;
- Wuhrer, Manfred;
- Schuurman, Janine;
- Labrijn, Aran F.;
- Rispens, Theo;
- Vidarsson, Gestur
Publication type:
Article
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-40731-2
By:
- Stapleton, Nigel M.;
- Brinkhaus, Maximilian;
- Armour, Kathryn L.;
- Bentlage, Arthur E. H.;
- de Taeye, Steven W.;
- Temming, A. Robin;
- Mok, Juk Yee;
- Brasser, Giso;
- Maas, Marielle;
- van Esch, Wim J. E.;
- Clark, Mike R.;
- Williamson, Lorna M.;
- van der Schoot, C. Ellen;
- Vidarsson, Gestur
Publication type:
Article
Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06659-8
By:
- de Taeye, Steven W.;
- Schriek, Angela I.;
- Umotoy, Jeffrey C.;
- Grobben, Marloes;
- Burger, Judith A.;
- Sanders, Rogier W.;
- Vidarsson, Gestur;
- Wuhrer, Manfred;
- Falck, David;
- Kootstra, Neeltje A.;
- van Gils, Marit J.
Publication type:
Article
Antibody Conjugates for Targeted Therapy Against HIV-1 as an Emerging Tool for HIV-1 Cure.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.708806
By:
- Umotoy, Jeffrey C.;
- de Taeye, Steven W.
Publication type:
Article
C-Reactive Protein Enhances IgG-Mediated Cellular Destruction Through IgG-Fc Receptors in vitro.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.594773
By:
- Temming, A. Robin;
- Tammes Buirs, Matthias;
- Bentlage, Arthur E. H.;
- Treffers, Louise W.;
- Feringa, Hannah;
- de Taeye, Steven W.;
- Kuijpers, Taco W.;
- Nagelkerke, Sietse Q.;
- Brasser, Giso;
- Mok, Juk Yee;
- van Esch, Wim J. E.;
- van den Berg, Timo K.;
- Rispens, Theo;
- van der Schoot, C. Ellen;
- Vidarsson, Gestur
Publication type:
Article
MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N -Glycosylation.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.02049
By:
- Sénard, Thomas;
- Gargano, Andrea F. G.;
- Falck, David;
- de Taeye, Steven W.;
- Rispens, Theo;
- Vidarsson, Gestur;
- Wuhrer, Manfred;
- Somsen, Govert W.;
- Domínguez-Vega, Elena
Publication type:
Article
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Published in:
Nature Communications, 2015, v. 6, n. 9, p. 8167, doi. 10.1038/ncomms9167
By:
- Lee, Jeong Hyun;
- Leaman, Daniel P.;
- Kim, Arthur S.;
- Torrents de la Peña, Alba;
- Sliepen, Kwinten;
- Yasmeen, Anila;
- Derking, Ronald;
- Ramos, Alejandra;
- de Taeye, Steven W.;
- Ozorowski, Gabriel;
- Klein, Florian;
- Burton, Dennis R.;
- Nussenzweig, Michel C.;
- Poignard, Pascal;
- Moore, John P.;
- Klasse, Per Johan;
- Sanders, Rogier W.;
- Zwick, Michael B.;
- Wilson, Ian A.;
- Ward, Andrew B.
Publication type:
Article
Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer.
Published in:
PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004767
By:
- Derking, Ronald;
- Ozorowski, Gabriel;
- Sliepen, Kwinten;
- Yasmeen, Anila;
- Cupo, Albert;
- Torres, Jonathan L.;
- Julien, Jean-Philippe;
- Lee, Jeong Hyun;
- van Montfort, Thijs;
- de Taeye, Steven W.;
- Connors, Mark;
- Burton, Dennis R.;
- Wilson, Ian A.;
- Klasse, Per-Johan;
- Ward, Andrew B.;
- Moore, John P.;
- Sanders, Rogier W.
Publication type:
Article
The Ligands for Human IgG and Their Effector Functions.
Published in:
Antibodies (2073-4468), 2019, v. 8, n. 2, p. 30, doi. 10.3390/antib8020030
By:
- de Taeye, Steven W.;
- Rispens, Theo;
- Vidarsson, Gestur
Publication type:
Article
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages.
Published in:
Science Translational Medicine, 2021, v. 13, n. 596, p. 1, doi. 10.1126/scitranslmed.abf8654
By:
- Hoepel, Willianne;
- Chen, Hung-Jen;
- Geyer, Chiara E.;
- Allahverdiyeva, Sona;
- Manz, Xue D.;
- de Taeye, Steven W.;
- Aman, Jurjan;
- Mes, Lynn;
- Steenhuis, Maurice;
- Griffith, Guillermo R.;
- Bonta, Peter I.;
- Brouwer, Philip J.M.;
- Caniels, Tom G.;
- van der Straten, Karlijn;
- Golebski, Korneliusz;
- Jonkers, René E.;
- Larsen, Mads D.;
- Linty, Federica;
- Nouta, Jan;
- van Roomen, Cindy P.A.A.
Publication type:
Article
HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds.
Published in:
Retrovirology, 2016, v. 13, p. 1, doi. 10.1186/s12977-016-0279-4
By:
- van den Kerkhof, Tom L. G. M.;
- de Taeye, Steven W.;
- Boeser-Nunnink, Brigitte D.;
- Burton, Dennis R.;
- Kootstra, Neeltje A.;
- Schuitemaker, Hanneke;
- Sanders, Rogier W.;
- van Gils, Marit J.
Publication type:
Article

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