Works matching AU de Ru, Arnoud H.

Results: 25

Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane.

Published in:

European Journal of Immunology, 2004, v. 34, n. 1, p. 156, doi. 10.1002/eji.200324241

By:

Verdijk, Pauline;
van Veelen, Peter A.;
de Ru, Arnoud H.;
Hensbergen, Paul J.;
Mizuno, Kensaku;
Koerten, Henk K.;
Koning, Frits;
Tensen, Cornelis P.;
Mommaas, A. Mieke

Publication type:

Article

Terminal α2,6-sialylation of epidermal growth factor receptor modulates antibody therapy response of colorectal cancer cells.

Published in:

Cellular Oncology (2211-3428), 2021, v. 44, n. 4, p. 835, doi. 10.1007/s13402-021-00606-z

By:

Rodrigues, Joana G.;
Duarte, Henrique O.;
Gomes, Catarina;
Balmaña, Meritxell;
Martins, Álvaro M.;
Hensbergen, Paul J.;
de Ru, Arnoud H.;
Lima, Jorge;
Albergaria, André;
van Veelen, Peter A.;
Wuhrer, Manfred;
Gomes, Joana;
Reis, Celso A.

Publication type:

Article

Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain.

Published in:

Journal of Hematology & Oncology, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13045-023-01408-6

By:

Meeuwsen, Miranda H.;
Wouters, Anne K.;
Wachsmann, Tassilo L. A.;
Hagedoorn, Renate S.;
Kester, Michel G. D.;
Remst, Dennis F. G.;
van der Steen, Dirk M.;
de Ru, Arnoud H.;
van Hees, Els P.;
Kremer, Martijn;
Griffioen, Marieke;
van Veelen, Peter A.;
Falkenburg, J. H. Frederik;
Heemskerk, Mirjam H. M.

Publication type:

Article

Hotspot DNA Methyltransferase 3A (DNMT3A) and Isocitrate Dehydrogenase 1 and 2 (IDH1/2) Mutations in Acute Myeloid Leukemia and Their Relevance as Targets for Immunotherapy.

Published in:

Biomedicines, 2024, v. 12, n. 5, p. 1086, doi. 10.3390/biomedicines12051086

By:

Struckman, Nadine E.;
de Jong, Rob C. M.;
Honders, M. Willy;
Smith, Sophie-Anne I.;
van der Lee, Dyantha I.;
Koutsoumpli, Georgia;
de Ru, Arnoud H.;
Mikesch, Jan-Henrik;
van Veelen, Peter A.;
Falkenburg, J. H. Frederik;
Griffioen, Marieke

Publication type:

Article

PRAME and CTCFL-reactive TCRs for the treatment of ovarian cancer.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1121973

By:

van Amerongen, Rosa A.;
Tuit, Sander;
Wouters, Anne K.;
van de Meent, Marian;
Siekman, Sterre L.;
Meeuwsen, Miranda H.;
Wachsmann, Tassilo L. A.;
Remst, Dennis F. G.;
Hagedoorn, Renate S.;
van der Steen, Dirk M.;
de Ru, Arnoud H.;
Verdegaal, Els M. E.;
van Veelen, Peter A.;
Falkenburg, J. H. Frederik;
Heemskerk, Mirjam H. M.

Publication type:

Article

Non‐prime‐ and prime‐side profiling of Pro‐Pro endopeptidase specificity using synthetic combinatorial peptide libraries and mass spectrometry.

Published in:

FEBS Journal, 2024, v. 291, n. 17, p. 3820, doi. 10.1111/febs.17160

By:

Claushuis, Bart;
Cordfunke, Robert A.;
de Ru, Arnoud H.;
van Angeren, Jordy;
Baumann, Ulrich;
van Veelen, Peter A.;
Wuhrer, Manfred;
Corver, Jeroen;
Drijfhout, Jan W.;
Hensbergen, Paul J.

Publication type:

Article

Specific T Cell Responses against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface.

Published in:

Proteomics, 2018, v. 18, n. 12, p. 1, doi. 10.1002/pmic.201700250

By:

Bijen, Helena M.;
Hassan, Chopie;
Kester, Michel G. D.;
Janssen, George M. C.;
Hombrink, Pleun;
de Ru, Arnoud H.;
Drijfhout, Jan Wouter;
Meiring, Hugo D.;
de Jong, Ad P.;
Falkenburg, J. H. Frederik;
Jimenez, Connie R.;
Heemskerk, Mirjam H. M.;
van Veelen, Peter A.

Publication type:

Article

Apparent Lack of BRAF V600E Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8+ T Cells in Langerhans Cell Histiocytosis.

Published in:

Frontiers in Immunology, 2020, v. 10, p. 1, doi. 10.3389/fimmu.2019.03045

By:

Kemps, Paul G.;
Zondag, Timo C.;
Steenwijk, Eline C.;
Andriessen, Quirine;
Borst, Jelske;
Vloemans, Sandra;
Roelen, Dave L.;
Voortman, Lenard M.;
Verdijk, Robert M.;
van Noesel, Carel J. M.;
Cleven, Arjen H. G.;
Hawkins, Cynthia;
Lang, Veronica;
de Ru, Arnoud H.;
Janssen, George M. C.;
Haasnoot, Geert W.;
Franken, Kees L. M. C.;
van Eijk, Ronald;
Solleveld-Westerink, Nienke;
van Wezel, Tom

Publication type:

Article

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48427-6

By:

Salas-Lloret, Daniel;
García-Rodríguez, Néstor;
Soto-Hidalgo, Emily;
González-Vinceiro, Lourdes;
Espejo-Serrano, Carmen;
Giebel, Lisanne;
Mateos-Martín, María Luisa;
de Ru, Arnoud H.;
van Veelen, Peter A.;
Huertas, Pablo;
Vertegaal, Alfred C. O.;
González-Prieto, Román

Publication type:

Article

Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule.

Published in:

Immunogenetics, 2008, v. 60, n. 9, p. 551, doi. 10.1007/s00251-008-0310-6

By:

Wiesner, Martina;
Stepniak, Dariusz;
De Ru, Arnoud H.;
Moustakis, Antonis K.;
Drijfhout, Jan W.;
Papadopoulos, George K.;
Van Veelen, Peter A.;
Koning, Frits

Publication type:

Article

Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.

Published in:

2019

By:

van Lummel, Menno;
Buis, David T. P.;
Ringeling, Cherish;
de Ru, Arnoud H.;
Pool, Jos;
Papadopoulos, George K.;
van Veelen, Peter A.;
Reijonen, Helena;
Drijfhout, Jan W.;
Roep, Bart O.

Publication type:

journal article

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule.

Published in:

2016

By:

van Lummel, Menno;
van Veelen, Peter A.;
de Ru, Arnoud H.;
Pool, Jos;
Nikolic, Tatjana;
Laban, Sandra;
Joosten, Antoinette;
Drijfhout, Jan W.;
Gómez-Touriño, Iria;
Arif, Sefina;
Aanstoot, Henk J.;
Peakman, Mark;
Roep, Bart O.

Publication type:

journal article

Proteolytic activity of surface‐exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile.

Published in:

Molecular Microbiology, 2024, v. 122, n. 4, p. 413, doi. 10.1111/mmi.15300

By:

Corver, Jeroen;
Claushuis, Bart;
Shamorkina, Tatiana M.;
de Ru, Arnoud H.;
van Leeuwen, Merle M.;
Hensbergen, Paul J.;
Smits, Wiep Klaas

Publication type:

Article

Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry.

Published in:

2021

By:

Lippold, Steffen;
Knaupp, Alexander;
de Ru, Arnoud H.;
Tjokrodirijo, Rayman T. N.;
van Veelen, Peter A.;
van Puijenbroek, Erwin;
de Taeye, Steven W.;
Reusch, Dietmar;
Vidarsson, Gestur;
Wuhrer, Manfred;
Schlothauer, Tilman;
Falck, David

Publication type:

Report

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

Published in:

Nature Biotechnology, 2022, v. 40, n. 4, p. 488, doi. 10.1038/s41587-021-01089-x

By:

Ali, Muhammad;
Giannakopoulou, Eirini;
Li, Yingqian;
Lehander, Madeleine;
Virding Culleton, Stina;
Yang, Weiwen;
Knetter, Cathrine;
Odabasi, Mete Can;
Bollineni, Ravi Chand;
Yang, Xinbo;
Foldvari, Zsofia;
Böschen, Maxi-Lu;
Taraldsrud, Eli;
Strønen, Erlend;
Toebes, Mireille;
Hillen, Amy;
Mazzi, Stefania;
de Ru, Arnoud H.;
Janssen, George M. C.;
Kolstad, Arne

Publication type:

Article

Oxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific O -Glycosylation of Anterior Gradient Protein 2 (AGR2).

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5369, doi. 10.3390/ijms22105369

By:

Pirro, Martina;
Mohammed, Yassene;
de Ru, Arnoud H.;
Janssen, George M. C.;
Tjokrodirijo, Rayman T. N.;
Madunić, Katarina;
Wuhrer, Manfred;
van Veelen, Peter A.;
Hensbergen, Paul J.;
Greco, Viviana;
Wessels, Hans J. C. T.

Publication type:

Article

N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5522, doi. 10.3390/ijms21155522

By:

Pirro, Martina;
Mohammed, Yassene;
van Vliet, Sandra J.;
Rombouts, Yoann;
Sciacca, Agnese;
de Ru, Arnoud H.;
Janssen, George M. C.;
Tjokrodirijo, Rayman T. N.;
Wuhrer, Manfred;
van Veelen, Peter A.;
Hensbergen, Paul J.

Publication type:

Article

Ligandomes obtained from different HLA-class II-molecules are homologous for N- and C-terminal residues outside the peptide-binding cleft.

Published in:

Immunogenetics, 2019, v. 71, n. 8/9, p. 519, doi. 10.1007/s00251-019-01129-6

By:

Kampstra, Arieke S.B.;
van Heemst, Jurgen;
Janssen, George M.;
de Ru, Arnoud H.;
van Lummel, Menno;
van Veelen, Peter A.;
Toes, René E.M.

Publication type:

Article

Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques.

Published in:

Immunogenetics, 2013, v. 65, n. 12, p. 897, doi. 10.1007/s00251-013-0734-5

By:

de Groot, Natasja G.;
Heijmans, Corrine M. C.;
de Ru, Arnoud H.;
Hassan, Chopie;
Otting, Nel;
Doxiadis, Gaby G. M.;
Koning, Frits;
van Veelen, Peter A.;
Bontrop, Ronald E.

Publication type:

Article

AMPK activation induces RALDH+ tolerogenic dendritic cells by rewiring glucose and lipid metabolism.

Published in:

Journal of Cell Biology, 2024, v. 223, n. 10, p. 1, doi. 10.1083/jcb.202401024

By:

Brombacher, Eline C.;
Patente, Thiago A.;
van der Ham, Alwin J.;
Moll, Tijmen J. A.;
Otto, Frank;
Verheijen, Fenne W. M.;
Zaal, Esther A.;
de Ru, Arnoud H.;
Tjokrodirijo, Rayman T. N.;
Berkers, Celia R.;
van Veelen, Peter A.;
Guigas, Bruno;
Everts, Bart

Publication type:

Article

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128206

By:

Hoelen, Hanneke;
Zaldumbide, Arnaud;
van Leeuwen, Wouter F.;
Torfs, Ellen C. W.;
Engelse, Marten A.;
Hassan, Chopie;
Lebbink, Robert Jan;
de Koning, Eelco J.;
Resssing, Maaike E.;
de Ru, Arnoud H.;
van Veelen, Peter A.;
Hoeben, Rob C.;
Roep, Bart O.;
Wiertz, Emmanuel J. H. J.

Publication type:

Article

Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034649

By:

Van Luijn, Marvin M.;
Van de Loosdrecht, Arjan A.;
Lampen, Margit H.;
Van Veelen, Peter A.;
Zevenbergen, Adri;
Kester, Michel G. D.;
De Ru, Arnoud H.;
Ossenkoppele, Gert J.;
Hall, Thorbald van;
van Ham, S. Marieke

Publication type:

Article

Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.831822

By:

Laghmouchi, Aicha;
Kester, Michel G. D.;
Hoogstraten, Conny;
Hageman, Lois;
de Klerk, Wendy;
Huisman, Wesley;
Koster, Eva A. S.;
de Ru, Arnoud H.;
van Balen, Peter;
Klobuch, Sebastian;
van Veelen, Peter A.;
Falkenburg, J. H. Frederik;
Jedema, Inge

Publication type:

Article

The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling.

Published in:

PLoS Pathogens, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.ppat.1011179

By:

Treffers, Emmely E.;
Tas, Ali;
Scholte, Florine E. M.;
de Ru, Arnoud H.;
Snijder, Eric J.;
van Veelen, Peter A.;
van Hemert, Martijn J.

Publication type:

Article

Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia.

Published in:

2019

By:

van der Lee, Dyantha I.;
Reijmers, Rogier M.;
Honders, Maria W.;
Hagedoorn, Renate S.;
de Jong, Rob C. M.;
Kester, Michel G. D.;
van der Steen, Dirk M.;
de Ru, Arnoud H.;
Kweekel, Christiaan;
Bijen, Helena M.;
Jedema, Inge;
Veelken, Hendrik;
van Veelen, Peter A.;
Heemskerk, Mirjam H. M.;
Falkenburg, J. H. Frederik;
Griffioen, Marieke;
de Jong, Rob Cm;
Kester, Michel Gd;
Heemskerk, Mirjam Hm

Publication type:

journal article

Works matching AU de Ru, Arnoud H.

Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane.

Terminal α2,6-sialylation of epidermal growth factor receptor modulates antibody therapy response of colorectal cancer cells.

Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain.

Hotspot DNA Methyltransferase 3A (DNMT3A) and Isocitrate Dehydrogenase 1 and 2 (IDH1/2) Mutations in Acute Myeloid Leukemia and Their Relevance as Targets for Immunotherapy.

PRAME and CTCFL-reactive TCRs for the treatment of ovarian cancer.

Non‐prime‐ and prime‐side profiling of Pro‐Pro endopeptidase specificity using synthetic combinatorial peptide libraries and mass spectrometry.

Specific T Cell Responses against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface.

Apparent Lack of BRAF <sup> V600E </sup> Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8<sup>+</sup> T Cells in Langerhans Cell Histiocytosis.

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.

Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule.

Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule.

Proteolytic activity of surface‐exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile.

Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry.

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

Oxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific O -Glycosylation of Anterior Gradient Protein 2 (AGR2).

N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity.

Ligandomes obtained from different HLA-class II-molecules are homologous for N- and C-terminal residues outside the peptide-binding cleft.

Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques.

AMPK activation induces RALDH<sup>+</sup> tolerogenic dendritic cells by rewiring glucose and lipid metabolism.

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells.

Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity.

The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling.

Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia.