Works by de Paiva, Cintia S.

Results: 41

Immune phenotype of the CD4<sup>+</sup> T cells in the aged lymphoid organs and lacrimal glands.

Published in:

GeroScience, 2022, v. 44, n. 4, p. 2105, doi. 10.1007/s11357-022-00529-z

By:

Trujillo-Vargas, Claudia M.;
Mauk, Kelsey E.;
Hernandez, Humberto;
de Souza, Rodrigo G.;
Yu, Zhiyuan;
Galletti, Jeremias G.;
Dietrich, Jana;
Paulsen, Friedrich;
de Paiva, Cintia S.

Publication type:

Article

An ocular Th1 immune response promotes corneal nerve damage independently of the development of corneal epitheliopathy.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02800-2

By:

Vereertbrugghen, Alexia;
Pizzano, Manuela;
Sabbione, Florencia;
Keitelman, Irene Angelica;
Shiromizu, Carolina Maiumi;
Aguilar, Douglas Vera;
Fuentes, Federico;
de Paiva, Cintia S.;
Giordano, Mirta;
Trevani, Analía;
Galletti, Jeremías G.

Publication type:

Article

Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1011125

By:

Mauduit, Olivier;
Delcroix, Vanessa;
Takeshi Umazume;
de Paiva, Cintia S.;
Dartt, Darlene A.;
Makarenkova, Helen P.

Publication type:

Article

MMP-8 Is Critical for Dexamethasone Therapy in Alkali-Burned Corneas Under Dry Eye Conditions.

Published in:

Journal of Cellular Physiology, 2016, v. 231, n. 11, p. 2506, doi. 10.1002/jcp.25364

By:

Bian, Fang;
Wang, Changjun;
Tukler ‐ Henriksson, Johanna;
Pflugfelder, Stephen C.;
Camodeca, Caterina;
Nuti, Elisa;
Rossello, Armando;
Li, De ‐ Quan;
de Paiva, Cintia S.

Publication type:

Article

Induction of Th17 differentiation by corneal epithelial-derived cytokines.

Published in:

Journal of Cellular Physiology, 2010, v. 222, n. 1, p. 95, doi. 10.1002/jcp.21926

By:

XIAOFEN ZHENG;
FANG BIAN;
PING MA;
DE PAIVA, CINTIA S.;
STERN, MICHAEL;
PFLUGFELDER, STEPHEN C.;
DE-QUAN LI

Publication type:

Article

On the nose: nasal neurostimulation as a technology countermeasure for sinonasal congestion in astronauts.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1536496

By:

Ax, Timon;
Zimmermann, Philipp H.;
Bothe, Tomas L.;
Barchetti, Karen;
de Paiva, Cintia S.;
March de Ribot, Francesc;
Jensen, Slade O.;
Millar, Thomas J.

Publication type:

Article

Altered balance of interleukin-13/interferongamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren's syndrome.

Published in:

Arthritis Research & Therapy, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13075-015-0582-9

By:

Bian, Fang;
Barbosa, Flavia L.;
Corrales, Rosa M.;
Pelegrino, Flavia S. A.;
Volpe, Eugene A.;
flugfelder, Stephen C. P.;
de Paiva, Cintia S.

Publication type:

Article

A Putative Role for RHAMM/HMMR as a Negative Marker of Stem Cell-Containing Population of Human Limbal Epithelial Cells.

Published in:

Stem Cells, 2008, v. 26, n. 6, p. 1609, doi. 10.1634/stemcells.2007-0782

By:

Ahmad, Sajjad;
Sai Kolli;
De-Quan Li;
De Paiva, Cintia S.;
Pryzborski, Stefan;
Dimmick, Ian;
Armstrong, Lyle;
Figueiredo, Francisco C.;
Lako, Majlinda

Publication type:

Article

Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1362336

By:

Alam, Jehan;
Yaman, Ebru;
Villalba Silva, Gerda Cristal;
Rui Chen;
de Paiva, Cintia S.;
Stepp, Mary Ann;
Pflugfelder, Stephen C.

Publication type:

Article

Age‐related changes in ocular mucosal tolerance: Lessons learned from gut and respiratory tract immunity.

Published in:

Immunology, 2021, v. 164, n. 1, p. 43, doi. 10.1111/imm.13338

By:

Galletti, Jeremias G.;
de Paiva, Cintia S.

Publication type:

Article

Author Correction: Gut-derived butyrate suppresses ocular surface inflammation.

Published in:

2022

By:

Schaefer, Laura;
Hernandez, Humberto;
Coats, Rosalind A.;
Yu, Zhiyuan;
Pflugfelder, Stephen C.;
Britton, Robert A.;
de Paiva, Cintia S.

Publication type:

Correction Notice

Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells.

Published in:

International Immunology, 2018, v. 30, n. 10, p. 457, doi. 10.1093/intimm/dxy045

By:

Xiao, Yangyan;
Paiva, Cintia S de;
Yu, Zhiyuan;
Souza, Rodrigo G de;
Li, De-Quan;
Pflugfelder, Stephen C

Publication type:

Article

Managing Sjögren's Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy.

Published in:

Clinical Ophthalmology, 2014, v. 8, p. 1447, doi. 10.2147/OPTH.S35685

By:

Coursey, Terry G.;
de Paiva, Cintia S.

Publication type:

Article

Calcineurin Inhibitor Voclosporin Preserves Corneal Barrier and Conjunctival Goblet Cells in Experimental Dry Eye.

Published in:

2020

By:

Alam, Jehan;
de Souza, Rodrigo G.;
Yu, Zhiyuan;
Stern, Michael E.;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

journal article

Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast.

Published in:

2018

By:

Guimaraes de Souza, Rodrigo;
Yu, Zhiyuan;
Stern, Michael E.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

journal article

Heterochronic Parabiosis Causes Dacryoadenitis in Young Lacrimal Glands.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4897, doi. 10.3390/ijms24054897

By:

Scholand, Kaitlin K.;
Mack, Alexis F.;
Guzman, Gary U.;
Maniskas, Michael E.;
Sampige, Ritu;
Govindarajan, Gowthaman;
McCullough, Louise D.;
de Paiva, Cintia S.

Publication type:

Article

Lacrimal Gland Epithelial Cells Shape Immune Responses through the Modulation of Inflammasomes and Lipid Metabolism.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4309, doi. 10.3390/ijms24054309

By:

Delcroix, Vanessa;
Mauduit, Olivier;
Yang, Menglu;
Srivastava, Amrita;
Umazume, Takeshi;
de Paiva, Cintia S.;
Shestopalov, Valery I.;
Dartt, Darlene A.;
Makarenkova, Helen P.

Publication type:

Article

A, B, C's of Trk Receptors and Their Ligands in Ocular Repair.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14069, doi. 10.3390/ijms232214069

By:

Gupta, Akash;
Galletti, Jeremias G.;
Yu, Zhiyuan;
Burgess, Kevin;
de Paiva, Cintia S.

Publication type:

Article

Functional Ambivalence of Dendritic Cells: Tolerogenicity and Immunogenicity.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4430, doi. 10.3390/ijms22094430

By:

Nam, Ji-Hee;
Lee, Jun-Ho;
Choi, So-Yeon;
Jung, Nam-Chul;
Song, Jie-Young;
Seo, Han-Geuk;
Lim, Dae-Seog;
Paiva, Cintia S. De

Publication type:

Article

Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3767, doi. 10.3390/ijms22073767

By:

Allred, Merri-Grace;
Chimenti, Michael S.;
Ciecko, Ashley E.;
Chen, Yi-Guang;
Lieberman, Scott M.;
De Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article

Blue Light Induces Impaired Autophagy through Nucleotide-Binding Oligomerization Domain 2 Activation on the Mouse Ocular Surface.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2015, doi. 10.3390/ijms22042015

By:

Li, Ying;
Jin, Rujun;
Li, Lan;
Choi, Ji Suk;
Kim, Jonghwa;
Yoon, Hyeon Jeong;
Park, Jong Hwan;
Yoon, Kyung Chul;
De Paiva, Cintia S.;
Pflugfelder, Stephen C.;
Holland, Martin J.

Publication type:

Article

Retinoid Regulation of Ocular Surface Innate Inflammation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1092, doi. 10.3390/ijms22031092

By:

Alam, Jehan;
Yu, Zhiyuan;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.;
Kurihara, Toshihide

Publication type:

Article

Parity Attenuates Intraepithelial Corneal Sensory Nerve Loss in Female Mice.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 5172, doi. 10.3390/ijms21145172

By:

Stepp, Mary Ann;
Pal-Ghosh, Sonali;
Tadvalkar, Gauri;
de Paiva, Cintia S.

Publication type:

Article

Mechanisms of Disease in Sjögren Syndrome—New Developments and Directions.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 2, p. 1, doi. 10.3390/ijms21020650

By:

de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article

Reduced Corneal Innervation in the CD25 Null Model of Sjögren Syndrome †.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3821, doi. 10.3390/ijms19123821

By:

Stepp, Mary Ann;
Pal-Ghosh, Sonali;
Tadvalkar, Gauri;
Williams, Alexa R.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

Article

Severity of Sjögren's Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2760, doi. 10.3390/ijms19092760

By:

Pflugfelder, Stephen C.;
Bian, Fang;
Gumus, Koray;
Farley, William;
Stern, Michael E.;
De Paiva, Cintia S.

Publication type:

Article

Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 565, doi. 10.3390/ijms19020565

By:

Wang, Changjun;
Zaheer, Mahira;
Bian, Fang;
Quach, Darin;
Swennes, Alton G.;
Britton, Robert A.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

Article

Goblet Cells Contribute to Ocular Surface Immune Tolerance—Implications for Dry Eye Disease.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 978, doi. 10.3390/ijms18050978

By:

Barbosa, Flavia L.;
Yangyan Xiao;
Fang Bian;
Coursey, Terry G.;
Byung Yi Ko;
Clevers, Hans;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 3, p. 562, doi. 10.3390/ijms18030562

By:

Fang Bian;
Yangyan Xiao;
Zaheer, Mahira;
Volpe, Eugene A.;
Pflugfelder, Stephen C.;
De-Quan Li;
De Paiva, Cintia S.

Publication type:

Article

Dry eye disease in astronauts: a narrative review.

Published in:

Frontiers in Physiology, 2023, p. 01, doi. 10.3389/fphys.2023.1281327

By:

Ax, Timon;
Ganse, Bergita;
Fries, Fabian N.;
Szentmáry, Nóra;
de Paiva, Cintia S.;
de Ribot, Francesc March;
Jensen, Slade O.;
Seitz, Berthold;
Millar, Thomas J.

Publication type:

Article

Altered Mucosal Microbiome Diversity and Disease Severity in Sjögren Syndrome.

Published in:

Scientific Reports, 2016, p. 23561, doi. 10.1038/srep23561

By:

de Paiva, Cintia S.;
Jones, Dan B.;
Stern, Michael E.;
Bian, Fang;
Moore, Quianta L.;
Corbiere, Shani;
Streckfus, Charles F.;
Hutchinson, Diane S.;
Ajami, Nadim J.;
Petrosino, Joseph F.;
Pflugfelder, Stephen C.

Publication type:

Article

Ectoine, from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease.

Published in:

Pharmaceutics, 2024, v. 16, n. 2, p. 236, doi. 10.3390/pharmaceutics16020236

By:

Chen, Xin;
Lin, Na;
Li, Jin-Miao;
Liu, Haixia;
Abu-Romman, Anmar;
Yaman, Ebru;
Bian, Fang;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Chemokine Receptors CCR6 and CXCR3 Are Necessary for CD4<sup>+</sup> T Cell Mediated Ocular Surface Disease in Experimental Dry Eye Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078508

By:

Coursey, Terry G.;
Gandhi, Niral B.;
Volpe, Eugene A.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

Article

A Native-Like Corneal Construct Using Donor Corneal Stroma for Tissue Engineering.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049571

By:

Jing Lin;
Kyung-Chul Yoon;
Lili Zhang;
Zhitao Su;
Rong Lu;
Ping Ma;
De Paiva, Cintia S.;
Pflugfelder, Stephen C.;
De-Quan Li

Publication type:

Article

NK Cells Promote Th-17 Mediated Corneal Barrier Disruption in Dry Eye.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036822

By:

Xiaobo Zhang;
Volpe, Eugene A.;
Gandhi, Niral B.;
Schaumburg, Chris S.;
Siemasko, Karyn F.;
Pangelinan, Solherny B.;
Kelly, Scott D.;
Hayday, Adrian C.;
De-Quan Li;
Stern, Michael E.;
Niederkorn, Jerry Y.;
Pflugfelder, Stephen C.;
Paiva, Cintia S. De

Publication type:

Article

Disruption of TGF-β Signaling Improves Ocular Surface Epithelial Disease in Experimental Autoimmune Keratoconjunctivitis Sicca.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029017

By:

De Paiva, Cintia S.;
Volpe, Eugene A.;
Gandhi, Niral B.;
Zhang, Xiaobo;
Zheng, Xiaofen;
Pitcher III, John D.;
Farley, William J.;
Stern, Michael E.;
Niederkorn, Jerry Y.;
Li, De-Quan;
Flavell, Richard A.;
Pflugfelder, Stephen C.

Publication type:

Article

The First Transcriptomic Atlas of the Adult Lacrimal Gland Reveals Epithelial Complexity and Identifies Novel Progenitor Cells in Mice.

Published in:

Cells (2073-4409), 2023, v. 12, n. 10, p. 1435, doi. 10.3390/cells12101435

By:

Delcroix, Vanessa;
Mauduit, Olivier;
Lee, Hyun Soo;
Ivanova, Anastasiia;
Umazume, Takeshi;
Knox, Sarah M.;
de Paiva, Cintia S.;
Dartt, Darlene A.;
Makarenkova, Helen P.

Publication type:

Article

Age-related T-cell cytokine profile parallels corneal disease severity in Sjögren’s syndrome-like keratoconjunctivitis sicca in CD25KO mice*.

Published in:

Rheumatology, 2010, v. 49, n. 2, p. 246, doi. 10.1093/rheumatology/kep357

By:

De Paiva, Cintia S.;
Hwang, Cindy S.;
Pitcher III, John D.;
Pangelinan, Solherny B.;
Rahimy, Ehsan;
Wei Chen;
Kyung-Chul Yoon;
Farley, William J.;
Niederkorn, Jerry Y.;
Stern, Michael E.;
De-Quan Li;
Pflugfelder, Stephen C.

Publication type:

Article

Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice.

Published in:

Arthritis Research & Therapy, 2012, v. 14, n. 6, p. 1, doi. 10.1186/ar4077

By:

Pelegrino, Flavia S. A.;
Volpe, Eugene A.;
Gandhi, Niral B.;
Li, De-Quan;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

Article

Differentially Expressed Gene Pathways in the Conjunctiva of Sjögren Syndrome Keratoconjunctivitis Sicca.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.702755

By:

de Paiva, Cintia S.;
Trujillo-Vargas, Claudia M.;
Schaefer, Laura;
Yu, Zhiyuan;
Britton, Robert A.;
Pflugfelder, Stephen C.

Publication type:

Article

Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.701415

By:

Alam, Jehan;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article