Works by de Opakua, Alain Ibáñez

Results: 18

Bestimmung der physikalisch‐chemischen Zusammensetzung von biomolekularen Kondensaten durch räumlich aufgelöste NMR.

Published in:

Angewandte Chemie, 2023, v. 135, n. 17, p. 1, doi. 10.1002/ange.202218078

By:

Pantoja, Christian F.;
Ibáñez de Opakua, Alain;
Cima‐Omori, Maria‐Sol;
Zweckstetter, Markus

Publication type:

Article

Bestimmung komplexer kleiner Molekülstrukturen mittels molekularer Ausrichtungssimulation.

Published in:

Angewandte Chemie, 2020, v. 132, n. 15, p. 6230, doi. 10.1002/ange.202000311

By:

Ibáñez de Opakua, Alain;
Klama, Frederik;
Ndukwe, Ikenna E.;
Martin, Gary E.;
Williamson, R. Thomas;
Zweckstetter, Markus

Publication type:

Article

A Novel SNCA A30G Mutation Causes Familial Parkinsonʼs Disease.

Published in:

Movement Disorders, 2021, v. 36, n. 7, p. 1624, doi. 10.1002/mds.28534

By:

Liu, Hui;
Koros, Christos;
Strohäker, Timo;
Schulte, Claudia;
Bozi, Maria;
Varvaresos, Stefanos;
Ibáñez de Opakua, Alain;
Simitsi, Athina Maria;
Bougea, Anastasia;
Voumvourakis, Konstantinos;
Maniati, Matina;
Papageorgiou, Sokratis G.;
Hauser, Ann‐Kathrin;
Becker, Stefan;
Zweckstetter, Markus;
Stefanis, Leonidas;
Gasser, Thomas

Publication type:

Article

Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24362-8

By:

Chakraborty, Pijush;
Rivière, Gwladys;
Liu, Shu;
de Opakua, Alain Ibáñez;
Dervişoğlu, Rıza;
Hebestreit, Alina;
Andreas, Loren B.;
Vorberg, Ina M.;
Zweckstetter, Markus

Publication type:

Article

Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23691-y

By:

Babu, Maria;
Favretto, Filippo;
de Opakua, Alain Ibáñez;
Rankovic, Marija;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

The tumor suppressor inhibitor of growth 4 binds double-stranded DNA through its disordered central region.

Published in:

FEBS Letters, 2017, v. 591, n. 2, p. 425, doi. 10.1002/1873-3468.12514

By:

Ormaza, Georgina;
Medagli, Barbara;
Ibáñez de Opakua, Alain;
Rodríguez, Jhon A.;
Merino, Nekane;
Villate, Maider;
Onesti, Silvia;
Blanco, Francisco J.

Publication type:

Article

Extending the applicability of P3D for structure determination of small molecules.

Published in:

Magnetic Resonance, 2021, v. 2, n. 1, p. 105, doi. 10.5194/mr-2-105-2021

By:

Ibáñez de Opakua, Alain;
Zweckstetter, Markus

Publication type:

Article

The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172507

By:

Ibáñez de Opakua, Alain;
Merino, Nekane;
Villate, Maider;
Cordeiro, Tiago N.;
Ormaza, Georgina;
Sánchez-Carbayo, Marta;
Diercks, Tammo;
Bernadó, Pau;
Blanco, Francisco J.

Publication type:

Article

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37561-2

By:

Rosado-Ramos, Rita;
Poças, Gonçalo M.;
Marques, Daniela;
Foito, Alexandre;
M. Sevillano, David;
Lopes-da-Silva, Mafalda;
Gonçalves, Luís G.;
Menezes, Regina;
Ottens, Marcel;
Stewart, Derek;
Ibáñez de Opakua, Alain;
Zweckstetter, Markus;
Seabra, Miguel C.;
Mendes, César S.;
Outeiro, Tiago Fleming;
Domingos, Pedro M.;
Santos, Cláudia N.

Publication type:

Article

Determining the Physico‐Chemical Composition of Biomolecular Condensates from Spatially‐Resolved NMR.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 17, p. 1, doi. 10.1002/anie.202218078

By:

Pantoja, Christian F.;
Ibáñez de Opakua, Alain;
Cima‐Omori, Maria‐Sol;
Zweckstetter, Markus

Publication type:

Article

Determination of Complex Small‐Molecule Structures Using Molecular Alignment Simulation.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 15, p. 6172, doi. 10.1002/anie.202000311

By:

Ibáñez de Opakua, Alain;
Klama, Frederik;
Ndukwe, Ikenna E.;
Martin, Gary E.;
Williamson, R. Thomas;
Zweckstetter, Markus

Publication type:

Article

Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 9, p. 1, doi. 10.1002/pro.4409

By:

Zachrdla, Milan;
Savastano, Adriana;
Ibáñez de Opakua, Alain;
Cima‐Omori, Maria‐Sol;
Zweckstetter, Markus

Publication type:

Article

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15163, doi. 10.1038/ncomms15163

By:

de Opakua, Alain Ibáñez;
Parag-Sharma, Kshitij;
DiGiacomo, Vincent;
Merino, Nekane;
Leyme, Anthony;
Marivin, Arthur;
Villate, Maider;
Nguyen, Lien T.;
de la Cruz-Morcillo, Miguel Angel;
Blanco-Canosa, Juan B.;
Ramachandran, Sekar;
Baillie, George S.;
Cerione, Richard A.;
Blanco, Francisco J.;
Garcia-Marcos, Mikel

Publication type:

Article

Structure of p15<sup>PAF</sup>-PCNA complex and implications for clamp sliding during DNA replication and repair.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6439, doi. 10.1038/ncomms7439

By:

De Biasio, Alfredo;
de Opakua, Alain Ibáñez;
Mortuza, Gulnahar B.;
Molina, Rafael;
Cordeiro, Tiago N.;
Castillo, Francisco;
Villate, Maider;
Merino, Nekane;
Delgado, Sandra;
Gil-Cartón, David;
Luque, Irene;
Diercks, Tammo;
Bernadó, Pau;
Montoya, Guillermo;
Blanco, Francisco J.

Publication type:

Article

Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.

Published in:

Biochemical Journal, 2014, v. 464, n. 1, p. 23, doi. 10.1042/BJ20140409

By:

Corral-Rodríguez, María Ángeles;
Stuiver, Marchel;
Abascal-Palacios, Guillermo;
Diercks, Tammo;
Oyenarte, Iker;
Ereño-Orbea, June;
de Opakua, Alain Ibáñez;
Blanco, Francisco J.;
Encinar, José Antonio;
Spiwok, Vojtêch;
Terashima, Hiroyuki;
Accardi, Alessio;
Müller, Dominik;
Martínez-Cruz, Luis Alfonso

Publication type:

Article

Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-69744-y

By:

Dominguez-Meijide, Antonio;
Vasili, Eftychia;
König, Annekatrin;
Cima-Omori, Maria-Sol;
Ibáñez de Opakua, Alain;
Leonov, Andrei;
Ryazanov, Sergey;
Zweckstetter, Markus;
Griesinger, Christian;
Outeiro, Tiago F.

Publication type:

Article

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19843-1

By:

Savastano, Adriana;
Ibáñez de Opakua, Alain;
Rankovic, Marija;
Zweckstetter, Markus

Publication type:

Article

The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.

Published in:

RNA Biology, 2014, v. 11, n. 10, p. 1250, doi. 10.1080/15476286.2014.996069

By:

Scheiba, Rafael M;
de Opakua, Alain Ibáñez;
Díaz-Quintana, Antonio;
Cruz-Gallardo, Isabel;
Martínez-Cruz, Luis A;
Martínez-Chantar, María L;
Blanco, Francisco J;
Díaz-Moreno, Irene

Publication type:

Article