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Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin's Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug.
- Published in:
- Cardiovascular Toxicology, 2024, v. 24, n. 3, p. 266, doi. 10.1007/s12012-024-09829-6
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- Publication type:
- Article
Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells.
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- Archives of Toxicology, 2023, v. 97, n. 1, p. 201, doi. 10.1007/s00204-022-03363-6
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- Publication type:
- Article
Ecstasy metabolites and monoamine neurotransmitters upshift the Na<sup>+</sup>/K<sup>+</sup> ATPase activity in mouse brain synaptosomes.
- Published in:
- Archives of Toxicology, 2022, v. 96, n. 12, p. 3279, doi. 10.1007/s00204-022-03370-7
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- Publication type:
- Article
Cardiotoxicity of cyclophosphamide's metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes.
- Published in:
- Archives of Toxicology, 2022, v. 96, n. 2, p. 653, doi. 10.1007/s00204-021-03204-y
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- Publication type:
- Article
Four decades of chemotherapy-induced cognitive dysfunction: comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events.
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- Archives of Toxicology, 2022, v. 96, n. 1, p. 11, doi. 10.1007/s00204-021-03171-4
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- Publication type:
- Article
An updated review on synthetic cathinones.
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- Archives of Toxicology, 2021, v. 95, n. 9, p. 2895, doi. 10.1007/s00204-021-03083-3
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- Publication type:
- Article
From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC.
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- Archives of Toxicology, 2021, v. 95, n. 4, p. 1443, doi. 10.1007/s00204-021-02990-9
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- Publication type:
- Article
In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV).
- Published in:
- Archives of Toxicology, 2021, v. 95, n. 2, p. 509, doi. 10.1007/s00204-020-02949-2
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- Publication type:
- Article
Adverse outcome pathways induced by 3,4-dimethylmethcathinone and 4-methylmethcathinone in differentiated human SH-SY5Y neuronal cells.
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- Archives of Toxicology, 2020, v. 94, n. 7, p. 2481, doi. 10.1007/s00204-020-02761-y
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- Publication type:
- Article
Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product.
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- Archives of Toxicology, 2020, v. 94, n. 4, p. 1071, doi. 10.1007/s00204-020-02675-9
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- Publication type:
- Article
Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models.
- Published in:
- Archives of Toxicology, 2020, v. 94, n. 2, p. 609, doi. 10.1007/s00204-019-02638-9
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- Publication type:
- Article
Metabolic signature of methylone in primary mouse hepatocytes, at subtoxic concentrations.
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- Archives of Toxicology, 2019, v. 93, n. 11, p. 3277, doi. 10.1007/s00204-019-02566-8
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- Publication type:
- Article
The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations.
- Published in:
- Archives of Toxicology, 2019, v. 93, n. 9, p. 2617, doi. 10.1007/s00204-019-02539-x
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- Publication type:
- Article
An effective antidotal combination of polymyxin B and methylprednisolone for α-amanitin intoxication.
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- Archives of Toxicology, 2019, v. 93, n. 5, p. 1449, doi. 10.1007/s00204-019-02426-5
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- Publication type:
- Article
GC–MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 11, p. 3307, doi. 10.1007/s00204-018-2314-9
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- Publication type:
- Article
Ethanol addictively enhances the in vitro cardiotoxicity of cocaine through oxidative damage, energetic deregulation, and apoptosis.
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- Archives of Toxicology, 2018, v. 92, n. 7, p. 2311, doi. 10.1007/s00204-018-2227-7
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- Publication type:
- Article
Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes.
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- Archives of Toxicology, 2011, v. 85, n. 8, p. 929, doi. 10.1007/s00204-010-0630-9
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- Publication type:
- Article
In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells.
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- Archives of Toxicology, 2011, v. 85, n. 4, p. 315, doi. 10.1007/s00204-010-0587-8
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- Publication type:
- Article
Discovery of Volatile Biomarkers for Bladder Cancer Detection and Staging through Urine Metabolomics.
- Published in:
- Metabolites (2218-1989), 2021, v. 11, n. 4, p. 199, doi. 10.3390/metabo11040199
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- Publication type:
- Article
Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years through Tissue and Urine Metabolomics.
- Published in:
- Metabolites (2218-1989), 2021, v. 11, n. 3, p. 181, doi. 10.3390/metabo11030181
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- Publication type:
- Article
Volatilomics Reveals Potential Biomarkers for Identification of Renal Cell Carcinoma: An In Vitro Approach.
- Published in:
- Metabolites (2218-1989), 2020, v. 10, n. 5, p. 174, doi. 10.3390/metabo10050174
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- Publication type:
- Article
Hepatic Metabolic Derangements Triggered by Hyperthermia: An In Vitro Metabolomic Study.
- Published in:
- Metabolites (2218-1989), 2019, v. 9, n. 10, p. 228, doi. 10.3390/metabo9100228
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- Publication type:
- Article
GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells.
- Published in:
- Metabolites (2218-1989), 2019, v. 9, n. 1, p. 18, doi. 10.3390/metabo9010018
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- Publication type:
- Article
GC-MS-Based Endometabolome Analysis Differentiates Prostate Cancer from Normal Prostate Cells.
- Published in:
- Metabolites (2218-1989), 2018, v. 8, n. 1, p. 23, doi. 10.3390/metabo8010023
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- Publication type:
- Article
A Panel of Urinary Volatile Biomarkers for Differential Diagnosis of Prostate Cancer from Other Urological Cancers.
- Published in:
- Cancers, 2020, v. 12, n. 8, p. 2017, doi. 10.3390/cancers12082017
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- Publication type:
- Article
Monoamine Oxidase-B Mediates Ecstasy-Induced Neurotoxic Effects to Adolescent Rat Brain Mitochondria.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 38, p. 10203, doi. 10.1523/JNEUROSCI.2645-07.2007
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- Publication type:
- Article
Influence of HTLV-1 in the clinic, microbiologic and immunologic features of tuberculosis.
- Published in:
- 2011
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- Publication type:
- Abstract
"Ecstasy" toxicity to adolescent rats following an acute low binge dose.
- Published in:
- BMC Pharmacology & Toxicology, 2016, v. 17, p. 1, doi. 10.1186/s40360-016-0070-0
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- Publication type:
- Article
The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 3, p. 98, doi. 10.3390/biom9030098
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- Publication type:
- Article
Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 1, p. 21, doi. 10.3390/biom9010021
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- Publication type:
- Article
Doping detection in animals: A review of analytical methodologies published from 1990 to 2019.
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- Drug Testing & Analysis, 2021, v. 13, n. 3, p. 474, doi. 10.1002/dta.2999
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- Publication type:
- Article
GC-MS metabolomics-based approach for the identification of a potential VOC-biomarker panel in the urine of renal cell carcinoma patients.
- Published in:
- Journal of Cellular & Molecular Medicine, 2017, v. 21, n. 9, p. 2092, doi. 10.1111/jcmm.13132
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- Publication type:
- Article
Inflammatory and immunological profiles in patients with COPD: relationship with FEV<sub>1</sub> reversibility.
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- Brazilian Journal of Pulmonology / Jornal Brasileiro de Pneumologia, 2016, v. 42, n. 4, p. 241, doi. 10.1590/S1806-37562015000000122
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- Publication type:
- Article
Lung function in the absence of respiratory symptoms in overweight children and adolescents.
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- Brazilian Journal of Pulmonology / Jornal Brasileiro de Pneumologia, 2014, v. 40, n. 2, p. 134
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- Publication type:
- Article
Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.
- Published in:
- Molecules, 2017, v. 22, n. 4, p. 600, doi. 10.3390/molecules22040600
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- Publication type:
- Article
Benzo fury: A new trend in the drug misuse scene.
- Published in:
- Journal of Applied Toxicology, 2019, v. 39, n. 8, p. 1083, doi. 10.1002/jat.3774
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- Publication type:
- Article
Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 369, n. 2, p. 198, doi. 10.1007/s00210-003-0850-0
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- Publication type:
- Article
Quantification of Methadone and Main Metabolites in Nails.
- Published in:
- Journal of Analytical Toxicology, 2018, v. 42, n. 3, p. 192, doi. 10.1093/jat/bkx099
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- Publication type:
- Article
Gold Nanoparticles Induce Oxidative Stress and Apoptosis in Human Kidney Cells.
- Published in:
- Nanomaterials (2079-4991), 2020, v. 10, n. 5, p. 995, doi. 10.3390/nano10050995
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- Publication type:
- Article
A Metabolomic Approach for the In Vivo Study of Gold Nanospheres and Nanostars after a Single-Dose Intravenous Administration to Wistar Rats.
- Published in:
- Nanomaterials (2079-4991), 2019, v. 9, n. 11, p. 1606, doi. 10.3390/nano9111606
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- Publication type:
- Article
Differential Effects of Methyl-4-Phenylpyridinium Ion, Rotenone, and Paraquat on Differentiated SH-SY5Y Cells.
- Published in:
- Journal of Toxicology, 2013, p. 1, doi. 10.1155/2013/347312
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- Publication type:
- Article
Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urine.
- Published in:
- 2019
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- Publication type:
- journal article
New findings on urinary prostate cancer metabolome through combined GC–MS and 1H NMR analytical platforms.
- Published in:
- Metabolomics, 2020, v. 16, n. 6, p. 1, doi. 10.1007/s11306-020-01691-1
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- Publication type:
- Article
NMR-based metabolomics studies of human prostate cancer tissue.
- Published in:
- Metabolomics, 2018, v. 14, n. 7, p. 1, doi. 10.1007/s11306-018-1384-2
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- Publication type:
- Article
Volatile metabolomic signature of bladder cancer cell lines based on gas chromatography-mass spectrometry.
- Published in:
- Metabolomics, 2018, v. 14, n. 5, p. 1, doi. 10.1007/s11306-018-1361-9
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- Publication type:
- Article
Influence of HTLV-1 on the clinical, microbiologic and immunologic presentation of tuberculosis.
- Published in:
- BMC Infectious Diseases, 2012, v. 12, n. 1, p. 199, doi. 10.1186/1471-2334-12-199
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- Publication type:
- Article
Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event.
- Published in:
- Cardiovascular Toxicology, 2013, v. 13, n. 4, p. 413, doi. 10.1007/s12012-013-9224-0
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- Publication type:
- Article
Quantification of 1-(propan-2-ylamino)-4-propoxy-9 H-thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein inducer/activator, in biological samples: method development and validation.
- Published in:
- Biomedical Chromatography, 2017, v. 31, n. 2, p. n/a, doi. 10.1002/bmc.3802
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- Publication type:
- Article
Evaluation of GSH adducts of adrenaline in biological samples.
- Published in:
- Biomedical Chromatography, 2007, v. 21, n. 7, p. 670, doi. 10.1002/bmc.796
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- Publication type:
- Article
Determination of amphetamine and its metabolite p-hydroxyamphetamine in rat urine by reversed-phase high-performance liquid chromatography after dabsyl derivatization.
- Published in:
- Biomedical Chromatography, 2001, v. 15, n. 7, p. 452, doi. 10.1002/bmc.93
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- Publication type:
- Article