Works by de Hoon, Jan


Results: 66
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    <sup>18</sup>F-JNJ-64413739, a Novel PET Ligand for the P2X7 Ion Channel: Radiation Dosimetry, Kinetic Modeling, Test-Retest Variability, and Occupancy of the P2X7 Antagonist JNJ-54175446.

    Published in:
    Journal of Nuclear Medicine, 2019, v. 60, n. 5, p. 683, doi. 10.2967/jnumed.118.216747
    By:
    • Koole, Michel;
    • Schmidt, Mark E.;
    • Hijzen, Anja;
    • Ravenstijn, Paulien;
    • Vandermeulen, Corinne;
    • Van Weehaeghe, Donatienne;
    • Serdons, Kim;
    • Celen, Sofie;
    • Bormans, Guy;
    • Ceusters, Marc;
    • Wei Zhang;
    • Van Nueten, Luc;
    • Kolb, Hartmuth;
    • de Hoon, Jan;
    • Van Laere, Koen
    Publication type:
    Article
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    <sup>11</sup>C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists.

    Published in:
    Journal of Nuclear Medicine, 2014, v. 55, n. 1, p. 65, doi. 10.2967/jnumed.113.122515
    By:
    • Van Laere, Koenraad J.;
    • Sanabria-Bohórquez, Sandra M.;
    • Mozley, David P.;
    • Burns, Donald H.;
    • Hamill, Terence G.;
    • Van Hecken, Anne;
    • De Lepeleire, Inge;
    • Koole, Michel;
    • Bormans, Guy;
    • de Hoon, Jan;
    • Depré, Marleen;
    • Cerchio, Kristine;
    • Plalcza, John;
    • Lingling Han;
    • Renger, John;
    • Hargreaves, Richard J.;
    • Iannone, Robert
    Publication type:
    Article
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    Pharmacokinetics of chemotherapeutic agents in pregnancy: a preclinical and clinical study.

    Published in:
    Acta Obstetricia et Gynecologica Scandinavica, 2010, v. 89, n. 10, p. 1338, doi. 10.3109/00016349.2010.512070
    By:
    • VAN CALSTEREN, KRISTEL;
    • VERBESSELT, RENÉ;
    • OTTEVANGER, NELLEKE;
    • HALASKA, MICHAEL;
    • HEYNS, LIESBETH;
    • VAN BREE, RIETA;
    • DE BRUIJN, ERNST;
    • CHAI, DANIEL;
    • DELFORGE, MICHEL;
    • NOENS, LUCIEN;
    • RENARD, VINCENT;
    • WITTEVEEN, ELS;
    • ROB, LUKAS;
    • DE HOON, JAN;
    • AMANT, FRÉDÉRIC
    Publication type:
    Article
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    Clinical validation of the novel HDAC6 radiotracer [18F]EKZ-001 in the human brain.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 2, p. 596, doi. 10.1007/s00259-020-04891-y
    By:
    • Koole, Michel;
    • Van Weehaeghe, Donatienne;
    • Serdons, Kim;
    • Herbots, Marissa;
    • Cawthorne, Christopher;
    • Celen, Sofie;
    • Schroeder, Frederick A.;
    • Hooker, Jacob M.;
    • Bormans, Guy;
    • de Hoon, Jan;
    • Kranz, Janice E.;
    • Van Laere, Koen;
    • Gilbert, Tonya M.
    Publication type:
    Article
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    Paracetamol pharmacokinetics and metabolism in young women.

    Published in:
    BMC Anesthesiology, 2015, v. 15, p. 1, doi. 10.1186/s12871-015-0144-3
    By:
    • Allegaert, Karel;
    • Peeters, Mariska Y.;
    • Beleyn, Bjorn;
    • Smits, Anne;
    • Kulo, Aida;
    • van Calsteren, Kristel;
    • Deprest, Jan;
    • de Hoon, Jan;
    • Knibbe, Catherijne A. J.
    Publication type:
    Article
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    Population Pharmacokinetic Analysis of Enalapril and Enalaprilat in Newly Treated Children with Heart Failure: Implications for Safe Dosing of Enalapril (LENA Studies).

    Published in:
    Clinical Pharmacokinetics, 2025, v. 64, n. 7, p. 1103, doi. 10.1007/s40262-025-01520-5
    By:
    • Steichert, Melina;
    • Cawello, Willi;
    • Laeer, Stephanie;
    • Breitkreutz, Jörg;
    • Klingmann, Ingrid;
    • Lagler, Florian;
    • de Hoon, Jan;
    • Dalinghaus, Michiel;
    • Bajcetic, Milica;
    • de Wildt, Saskia N.;
    • Keatley-Clarke, Anne;
    • Breur, Johannes M. P. J.;
    • Male, Christoph;
    • Ablonczy, Laszlo;
    • Mir, Thomas;
    • Vukomanovic, Vladislav;
    • Dukic, Milan;
    • Jovanovic, Ida;
    • Burckhardt, Bjoern B.;
    • Kleine, Karl
    Publication type:
    Article
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    Multiple-Dose Pharmacokinetics, Pharmacodynamics, and Safety of Taranabant, a Novel Selective Cannabinoid-1 Receptor Inverse Agonist, in Healthy Male Volunteers.

    Published in:
    Journal of Clinical Pharmacology, 2008, v. 48, n. 6, p. 734, doi. 10.1177/0091270008317591
    By:
    • Addy, Carol;
    • Rothenberg, Paul;
    • Susie Li;
    • Majumdar, Anup;
    • Agrawal, Nancy;
    • Hankun Li;
    • Ling Zhong;
    • Jinyu Yuan;
    • Maes, Andrea;
    • Dunbar, Stephanie;
    • Cote, Josee;
    • Rosko, Kim;
    • Van Dyck, Kristien;
    • De Lepeleire, Inge;
    • De Hoon, Jan;
    • Van Hecken, Anne;
    • Depré, Marleen;
    • Knops, Annemie;
    • Gottesdiener, Keith;
    • Stoch, Aubrey
    Publication type:
    Article
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