Works by de Haan, Gerald

Results: 39

Hematopoietic stem cell expansion: challenges and opportunities.

Published in:

Annals of the New York Academy of Sciences, 2012, v. 1266, n. 1, p. 138, doi. 10.1111/j.1749-6632.2012.06549.x

By:

Walasek, Marta A.;
van Os, Ronald;
de Haan, Gerald

Publication type:

Article

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0461-z

By:

Ackermann, Tobias;
Hartleben, Götz;
Müller, Christine;
Mastrobuoni, Guido;
Groth, Marco;
Sterken, Britt A.;
Zaini, Mohamad A.;
Youssef, Sameh A.;
Zuidhof, Hidde R.;
Krauss, Sara R.;
Kortman, Gertrud;
de Haan, Gerald;
de Bruin, Alain;
Wang, Zhao-Qi;
Platzer, Matthias;
Kempa, Stefan;
Calkhoven, Cornelis F.

Publication type:

Article

Targeted methods for epigenetic age predictions in mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-79509-2

By:

Han, Yang;
Nikolić, Miloš;
Gobs, Michael;
Franzen, Julia;
de Haan, Gerald;
Geiger, Hartmut;
Wagner, Wolfgang

Publication type:

Article

Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.

Published in:

Nature Cell Biology, 2013, v. 15, n. 4, p. 353, doi. 10.1038/ncb2701

By:

Klauke, Karin;
Radulović, Višnja;
Broekhuis, Mathilde;
Weersing, Ellen;
Zwart, Erik;
Olthof, Sandra;
Ritsema, Martha;
Bruggeman, Sophia;
Wu, Xudong;
Helin, Kristian;
Bystrykh, Leonid;
de Haan, Gerald

Publication type:

Article

How CBX proteins regulate normal and leukemic blood cells.

Published in:

FEBS Letters, 2024, v. 598, n. 22, p. 2788, doi. 10.1002/1873-3468.14839

By:

de Groot, Anne P.;
de Haan, Gerald

Publication type:

Article

Genetic control of lifespan: studies from animal models.

Published in:

Expert Reviews in Molecular Medicine, 1999, v. 1, n. 20, p. 1, doi. 10.1017/S1462399499001441

By:

Van Zant, Gary;
de Haan, Gerald

Publication type:

Article

Keratinocyte Growth Factor Prevents Radiation Damage to Salivary Glands by Expansion of the Stem/Progenitor Pool.

Published in:

Stem Cells, 2008, v. 26, n. 10, p. 2595, doi. 10.1634/stemcells.2007-1034

By:

Lombaert, Isabelle M. A.;
Brunsting, Jeanette F.;
Wierenga, Pieter K.;
Kampinga, Harm H.;
de Haan, Gerald;
Coppes, Robert P.

Publication type:

Article

A Limited Role for p21<sup>Cip1/Waf1</sup> in Maintaining Normal Hematopoietic Stem Cell Functioning.

Published in:

Stem Cells, 2007, v. 25, n. 4, p. 836, doi. 10.1634/stemcells.2006-0631

By:

van Os, Ronald;
Kamminga, Leonie M.;
Ausema, Albertina;
Bystrykh, Leonid V.;
Draijer, Deanna P.;
van Pelt, Kyrjon;
Dontje, Bert;
de Haan, Gerald

Publication type:

Article

Fibroblast Growth Factor-1 and -2 Preserve Long-Term Repopulating Ability of Hematopoietic Stem Cells in Serum-Free Cultures.

Published in:

Stem Cells, 2006, v. 24, n. 6, p. 1564, doi. 10.1634/stemcells.2005-0439

By:

Yeoh, Joyce S.G.;
van Os, Ronald;
Weersing, Ellen;
Ausema, Albertina;
Dontje, Bert;
Vellenga, Edo;
de Haan, Gerald

Publication type:

Article

Latexin is a newly discovered regulator of hematopoietic stem cells.

Published in:

Nature Genetics, 2007, v. 39, n. 2, p. 141, doi. 10.1038/ng0207-141

By:

de Haan, Gerald

Publication type:

Article

Reply to “Normalization procedures and detection of linkage signal in genetical-genomics experiments”.

Published in:

2006

By:

Chesler, Elissa J.;
Bystrykh, Leonid;
de Haan, Gerald;
Cooke, Michael P.;
Su, Andrew;
Manly, Kenneth F.;
Williams, Robert W.

Publication type:

Letter

Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.

Published in:

Nature Genetics, 2005, v. 37, n. 3, p. 225, doi. 10.1038/ng1497

By:

Bystrykh, Leonid;
Weersing, Ellen;
Dontje, Bert;
Sutton, Sue;
Pletcher, Mathew T;
Wiltshire, Tim;
Su, Andrew I;
Vellenga, Edo;
Wang, Jintao;
Manly, Kenneth F;
Lu, Lu;
Chesler, Elissa J;
Alberts, Rudi;
Jansen, Ritsert C;
Williams, Robert W;
Cooke, Michael P;
de Haan, Gerald

Publication type:

Article

A putative gene causes variability in lifespan among genotypically identical mice.

Published in:

Nature Genetics, 1998, v. 19, n. 2, p. 114, doi. 10.1038/465

By:

de Haan, Gerald;
Gelman, Rebecca;
Watson, Ada;
Yunis, Edmond;
Van Zant, Gary

Publication type:

Article

Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny.

Published in:

Immunogenetics, 2008, v. 60, n. 8, p. 411, doi. 10.1007/s00251-008-0305-3

By:

Gerrits, Alice;
Dykstra, Brad;
Otten, Marcel;
Bystrykh, Leonid;
de Haan, Gerald

Publication type:

Article

A Statistical Multiprobe Model for Analyzing cis and trans Genes in Genetical Genomics Experiments With Short-Oligonucleotide Arrays.

Published in:

Genetics, 2005, v. 171, n. 3, p. 1437, doi. 10.1534/genetics.105.045930

By:

Alberts, Rudi;
Terpstra, Peter;
Bystrykh, Leonid V.;
de Haan, Gerald;
Jansen, Ritsert C.

Publication type:

Article

MEDU-07. THE DEVELOPMENTAL STAGE OF THE MEDULLOBLASTOMA CELL-OF-ORIGIN IS MAINTAINED IN CANCER AND RESTRICTS HEDGEHOG PATHWAY USAGE AND DRUG SENSITIVITY.

Published in:

Neuro-Oncology, 2019, v. 21, p. ii104, doi. 10.1093/neuonc/noz036.167

By:

Smit, Marlinde;
Armandari, Inna;
Bockaj, Irena;
Martini, Tosca;
Zomerman, Walderik;
Siragna, Zillah;
Boer, Tiny Meeuwsen-de;
Scherpen, Frank;
Schoots, Mirthe;
Ritsema, Martha;
Dunnen, Wilfred den;
Hoving, Eelco;
Paridaen, Judith;
Haan, Gerald de;
Guryev, Victor;
Bruggeman, Sophia

Publication type:

Article

Polycomb group proteins in hematopoietic stem cell aging and malignancies.

Published in:

2011

By:

Klauke, Karin;
Haan, Gerald;
de Haan, Gerald

Publication type:

journal article

Hematopoietic Stem Cells: Self-Renewing or Aging?

Published in:

Cells Tissues Organs, 2002, v. 171, n. 1, p. 27, doi. 10.1159/000057689

By:

De Haan, Gerald

Publication type:

Article

MiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clones.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38503-z

By:

Wojtowicz, Edyta Ewa;
Broekhuis, Mathilde Johanna Christina;
Weersing, Ellen;
Dinitzen, Alexander;
Verovskaya, Evgenia;
Ausema, Albertina;
Ritsema, Martha;
Zwart, Erik;
de Haan, Gerald;
Bystrykh, Leonid V.

Publication type:

Article

Counting stem cells: methodological constraints.

Published in:

Nature Methods, 2012, v. 9, n. 6, p. 567, doi. 10.1038/nmeth.2043

By:

Bystrykh, Leonid V;
Verovskaya, Evgenia;
Zwart, Erik;
Broekhuis, Mathilde;
de Haan, Gerald

Publication type:

Article

Inferring combinatorial association logic networks in multimodal genome-wide screens.

Published in:

Bioinformatics, 2010, v. 26, n. 12, p. i149, doi. 10.1093/bioinformatics/btq211

By:

De Ridder, Jeroen;
Gerrits, Alice;
Bot, Jan;
De Haan, Gerald;
Reinders, Marcel;
Wessels, Lodewyk

Publication type:

Article

Regenerative medicine funding policies in Europe and The Netherlands.

Published in:

NPJ Regenerative Medicine, 2017, v. 2, n. 1, p. N.PAG, doi. 10.1038/s41536-016-0006-8

By:

de Haan, Gerald;
de Crom, Rini;
Dzierzak, Elaine;
Mummery, Christine

Publication type:

Article

A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, human and rat.

Published in:

BMC Bioinformatics, 2007, v. 8, p. 132, doi. 10.1186/1471-2105-8-132

By:

Alberts, Rudi;
Terpstra, Peter;
Hardonk, Menno;
Bystrykh, Leonid V;
de Haan, Gerald;
Breitling, Rainer;
Nap, Jan-Peter;
Jansen, Ritsert C

Publication type:

Article

Epigenetic Control of Hematopoietic Stem Cell Aging The Case of Ezh2.

Published in:

Annals of the New York Academy of Sciences, 2007, v. 1106, p. 233, doi. 10.1196/annals.1392.008

By:

De HAAN, GERALD;
GERRITS, ALICE

Publication type:

Article

Shared Ageing Research Models (ShARM): a new facility to support ageing research.

Published in:

Biogerontology, 2013, v. 14, n. 6, p. 789, doi. 10.1007/s10522-013-9457-0

By:

Duran, Adele L.;
Potter, Paul;
Wells, Sara;
Kirkwood, Tom;
von Zglinicki, Thomas;
McArdle, Anne;
Scudamore, Cheryl;
Meng, Qing-Jun;
de Haan, Gerald;
Corcoran, Anne;
Bellantuono, Ilaria

Publication type:

Article

Rescue of Salivary Gland Function after Stem Cell Transplantation in Irradiated Glands.

Published in:

PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0002063

By:

Lombaert, Isabelle M. A.;
Brunsting, Jeanette F.;
Wierenga, Pieter K.;
Faber, Hette;
Stokman, Monique A.;
Kok, Tineke;
Visser, Willy H.;
Kampinga, Harm H.;
de Haan, Gerald;
Coppes, Robert P.

Publication type:

Article

The ageing haematopoietic stem cell compartment.

Published in:

Nature Reviews Immunology, 2013, v. 13, n. 5, p. 376, doi. 10.1038/nri3433

By:

Geiger, Hartmut;
de Haan, Gerald;
Florian, M. Carolina

Publication type:

Article

Inflammation and Aging of Hematopoietic Stem Cells in Their Niche.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 1849, doi. 10.3390/cells10081849

By:

Yang, Daozheng;
de Haan, Gerald

Publication type:

Article

Epigenetic Changes as a Target in Aging Haematopoietic Stem Cells and Age-Related Malignancies.

Published in:

Cells (2073-4409), 2019, v. 8, n. 8, p. 868, doi. 10.3390/cells8080868

By:

Buisman, Sonja C.;
de Haan, Gerald

Publication type:

Article

Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?

Published in:

Human Molecular Genetics, 2006, v. 15, n. 2, p. r210, doi. 10.1093/hmg/ddl175

By:

Rizo, Aleksandra;
Vellenga, Edo;
de Haan, Gerald;
Schuringa, Jan Jacob

Publication type:

Article

Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?

Published in:

Human Molecular Genetics, 2006, v. 15, n. suppl_2, p. R210, doi. 10.1093/hmg/ddl175

By:

Rizo, Aleksandra;
Vellenga, Edo;
de Haan, Gerald;
Schuringa, Jan Jacob

Publication type:

Article

Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32970-1

By:

Kim, Kyung Mok;
Mura-Meszaros, Anna;
Tollot, Marie;
Krishnan, Murali Shyam;
Gründl, Marco;
Neubert, Laura;
Groth, Marco;
Rodriguez-Fraticelli, Alejo;
Svendsen, Arthur Flohr;
Campaner, Stefano;
Andreas, Nico;
Kamradt, Thomas;
Hoffmann, Steve;
Camargo, Fernando D.;
Heidel, Florian H.;
Bystrykh, Leonid V.;
de Haan, Gerald;
von Eyss, Björn

Publication type:

Article

Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands.

Published in:

Stem Cells, 2016, v. 34, n. 3, p. 640, doi. 10.1002/stem.2278

By:

Pringle, Sarah;
Maimets, Martti;
van der Zwaag, Marianne;
Stokman, Monique A.;
van Gosliga, Djoke;
Zwart, Erik;
Witjes, Max J.H.;
de Haan, Gerald;
van Os, Ronald;
Coppes, Rob P.

Publication type:

Article

Undifferentiated Embryonic Cell Transcription Factor 1 Regulates ESC Chromatin Organization and Gene Expression.

Published in:

Stem Cells, 2010, v. 28, n. 10, p. 1703, doi. 10.1002/stem.497

By:

Kooistra, Susanne M.;
van den Boom, Vincent;
Thummer, Rajkumar P.;
Johannes, Frank;
Wardenaar, René;
Tesson, Bruno M.;
Veenhoff, Liesbeth M.;
Fusetti, Fabrizia;
O'Neill, Laura P.;
Turner, Bryan M.;
de Haan, Gerald;
Eggen, Bart J. L.

Publication type:

Article

Concepts of Hemopoietic Cell Amplification. Synergy, Redundancy and Pleiotropy of Cytokines Affecting the Regulation of Erythropoiesis.

Published in:

Leukemia & Lymphoma, 1996, v. 22, n. 5/6, p. 385, doi. 10.3109/10428199609054776

By:

de Haan, Gerald;
Dontje, Bert;
Nijhof, Willem

Publication type:

Article

Identification of quantitative trait loci regulating haematopoietic parameters in B6AKRF2 mice.

Published in:

British Journal of Haematology, 2006, v. 132, n. 1, p. 80, doi. 10.1111/j.1365-2141.2005.05835.x

By:

van Os, Ronald;
Ausema, Albertina;
Noach, Estelle J. K.;
van Pelt, Kyrjon;
Dontje, Bert J. H.;
Vellenga, Edo;
de Haan, Gerald

Publication type:

Article

Efficient mobilization of haematopoietic progenitors after a single injection of pegylated recombinant human granulocyte colony-stimulating factor in mouse strains with distinct marrow-cell pool sizes.

Published in:

British Journal of Haematology, 2000, v. 110, n. 3, p. 638, doi. 10.1046/j.1365-2141.2000.02252.x

By:

de Haan, Gerald;
Ausema, Albertina;
Wilkens, Marga;
Molineux, Graham;
Dontje, Bert

Publication type:

Article

Expression Quantitative Trait Loci Are Highly Sensitive to Cellular Differentiation State.

Published in:

PLoS Genetics, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.pgen.1000692

By:

Gerrits, Alice;
Yang Li;
Tesson, Bruno M.;
Bystrykh, Leonid V.;
Weersing, Ellen;
Ausema, Albertina;
Dontje, Bert;
Xusheng Wang;
Breitling, Rainer;
Jansen, Ritsert C.;
de Haan, Gerald

Publication type:

Article

Genetical Genomics: Spotlight on QTL Hotspots.

Published in:

2008

By:

Breitling, Rainer;
Yang Li;
Tesson, Bruno M.;
Jingyuan Fu;
Chunlei Wu;
Wiltshire, Tim;
Gerrits, Alice;
Bystrykh, Leonid V.;
de Haan, Gerald;
Su, Andrew I.;
Ritsert C. Jansen

Publication type:

Opinion