Works by de Bruyn, Marco

Results: 27

Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101369

By:

Bhattacharya, Arkajyoti;
Stutvoet, Thijs S.;
Perla, Mirela;
Loipfinger, Stefan;
Jalving, Mathilde;
Reyners, Anna K. L.;
Vermeer, Paola D.;
Drapkin, Ronny;
de Bruyn, Marco;
de Vries, Elisabeth G. E.;
de Jong, Steven;
Fehrmann, Rudolf S. N.

Publication type:

Article

ImmunoPET provides a novel way to visualize the CD103+ tissue-resident memory T cell to predict the response of immune checkpoint inhibitors.

Published in:

EJNMMI Research, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13550-023-01062-6

By:

Fan, Xiaoyu;
Nijman, Hans W.;
de Bruyn, Marco;
Elsinga, Philip H.

Publication type:

Article

Development of [89Zr]Zr-hCD103.Fab01A and [68Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET.

Published in:

EJNMMI Research, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13550-023-01043-9

By:

Fan, Xiaoyu;
Ważyńska, Marta A.;
Kol, Arjan;
Perujo Holland, Noemi;
Fernandes, Bruna;
van Duijnhoven, Sander M. J.;
Plat, Annechien;
van Eenennaam, Hans;
Elsinga, Philip H.;
Nijman, Hans W.;
de Bruyn, Marco

Publication type:

Article

The Novel Immune Checkpoint GPR56 Is Expressed on Tumor-Infiltrating Lymphocytes and Selectively Upregulated upon TCR Signaling.

Published in:

Cancers, 2022, v. 14, n. 13, p. N.PAG, doi. 10.3390/cancers14133164

By:

Bilemjian, Vrouyr;
Vlaming, Martijn R.;
Álvarez Freile, Jimena;
Huls, Gerwin;
De Bruyn, Marco;
Bremer, Edwin

Publication type:

Article

Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer.

Published in:

Cancers, 2022, v. 14, n. 8, p. 1924, doi. 10.3390/cancers14081924

By:

Lubbers, Joyce M.;
Ważyńska, Marta A.;
van Rooij, Nienke;
Kol, Arjan;
Workel, Hagma H.;
Plat, Annechien;
Paijens, Sterre T.;
Vlaming, Martijn R.;
Spierings, Diana C. J.;
Elsinga, Philip H.;
Bremer, Edwin;
Nijman, Hans W.;
de Bruyn, Marco

Publication type:

Article

Prognostic benefit of TILs independent of clinicopathological and molecular factors.

Published in:

2023

By:

Brummel, Koen;
Eerkens, Anneke L.;
de Bruyn, Marco;
Nijman, Hans W.

Publication type:

Letter

Tumour-infiltrating lymphocytes: from prognosis to treatment selection.

Published in:

British Journal of Cancer, 2023, v. 128, n. 3, p. 451, doi. 10.1038/s41416-022-02119-4

By:

Brummel, Koen;
Eerkens, Anneke L.;
de Bruyn, Marco;
Nijman, Hans W.

Publication type:

Article

Carbon monoxide-Releasing Molecule-2 (CORM-2) attenuates acute hepatic ischemia reperfusion injury in rats.

Published in:

BMC Gastroenterology, 2010, v. 10, p. 42, doi. 10.1186/1471-230X-10-42

By:

Yunwei Wei;
Ping Chen;
de Bruyn, Marco;
Weihui Zhang;
Bremer, Edwin;
Helfrich, Wijnand

Publication type:

Article

Tumor infiltrating CD8/CD103/ TIM-3-expressing lymphocytes in epithelial ovarian cancer coexpress CXCL13 and associate with improved survival.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1031746

By:

Vlaming, Martijn;
Bilemjian, Vrouyr;
Álvarez Freile, Jimena;
Melo, Vinicio;
Plat, Annechien;
Huls, Gerwin;
Nijman, Hans W.;
Bruyn, Marco de;
Bremer, Edwin

Publication type:

Article

Targeted delivery of CD40L promotes restricted activation of antigen-presenting cells and induction of cancer cell death.

Published in:

Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-85

By:

Brunekreeft, Kim L.;
Strohm, Corinna;
Gooden, Marloes J.;
Rybczynska, Anna A.;
Nijman, Hans W.;
Grigoleit, Götz U.;
Helfrich, Wijnand;
Bremer, Edwin;
Siegmund, Daniela;
Wajant, Harald;
de Bruyn, Marco

Publication type:

Article

Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanomaoutgrowth in vitro and in vivo.

Published in:

Molecular Cancer, 2010, v. 9, p. 301, doi. 10.1186/1476-4598-9-301

By:

de Bruyn, Marco;
Rybczynska, Anna A.;
Yunwei Wei;
Schwenkert, Michael;
Fey, Georg H.;
Dierckx, Rudi A. J. O.;
van ^Waarde, Aren;
Helfrich, Wijnand;
Bremer, Edwin

Publication type:

Article

Targeted delivery of a designed sTRAIL mutant results in superior apoptotic activity towards EGFR-positive tumor cells.

Published in:

Journal of Molecular Medicine, 2008, v. 86, n. 8, p. 909, doi. 10.1007/s00109-008-0348-9

By:

Bremer, Edwin;
De Bruyn, Marco;
Samplonius, Douwe F.;
Bijma, Theo;
Ten Cate, Bram;
De Leij, Lou F. M. H.;
Helfrich, Wijnand

Publication type:

Article

B cells critical for outcome in high grade serous ovarian carcinoma.

Published in:

International Journal of Cancer, 2024, v. 155, n. 12, p. 2265, doi. 10.1002/ijc.35149

By:

Vledder, Annegé;
Paijens, Sterre T.;
Loiero, Dominik;
Maagdenberg, Alexis;
Duiker, Evelien W.;
Bart, Joost;
Hendriks, Anne M.;
Jalving, Mathilde;
Werner, Naomi;
van Rooij, Nienke;
Plat, Annechien;
Wisman, G. Bea A.;
Yigit, Refika;
Roelofsen, Thijs;
Kruse, Arnold J.;
de Lange, Nastascha M.;
Koelzer, Viktor H.;
de Bruyn, Marco;
Nijman, Hans W.

Publication type:

Article

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08013-z

By:

He, Yuan;
Bouwstra, Renee;
Wiersma, Valerie R.;
de Jong, Mathilde;
Jan Lourens, Harm;
Fehrmann, Rudolf;
de Bruyn, Marco;
Ammatuna, Emanuele;
Huls, Gerwin;
van Meerten, Tom;
Bremer, Edwin

Publication type:

Article

Lymphadenectomy and Adjuvant Therapy Improve Survival with Uterine Carcinosarcoma: A Large Retrospective Cohort Study.

Published in:

Oncology, 2018, v. 95, n. 2, p. 100, doi. 10.1159/000488531

By:

Versluis, Marco A.C.;
Pielsticker, Cindy;
van der Aa, Maaike A.;
de Bruyn, Marco;
Hollema, Harry;
Nijman, Hans W.

Publication type:

Article

The ever-expanding immunomodulatory role of calreticulin in cancer immunity.

Published in:

Frontiers in Oncology, 2015, v. 5, p. 1, doi. 10.3389/fonc.2015.00035

By:

de Bruyn, Marco;
Wiersma, Valerie R.;
Helfrich, Wijnand;
Bremer, Edwin;
Eggleton, Paul

Publication type:

Article

C-type lectin-like molecule-1 (CLL1)-targeted TRAIL augments the tumoricidal activity of granulocytes and potentiates therapeutic antibody-dependent cell-mediated cytotoxicity.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 2, p. 321, doi. 10.1080/19420862.2015.1007811

By:

Wiersma, Valerie R;
de Bruyn, Marco;
Shi, Ce;
Gooden, Marloes JM;
Wouters, Maartje CA;
Samplonius, Douwe F;
Hendriks, Djoke;
Nijman, Hans W;
Wei, Yunwei;
Zhou, Jin;
Helfrich, Wijnand;
Bremer, Edwin

Publication type:

Article

In Vivo Responses of Human A375M Melanoma to a σ Ligand: 18F-FDG PET Imaging.

Published in:

Journal of Nuclear Medicine, 2013, v. 54, n. 9, p. 1613, doi. 10.2967/jnumed.113.122655

By:

Rybczynska, Anna A.;
de Bruyn, Marco;
Ramakrishnan, Nisha K.;
de Jong, Johan R.;
Elsinga, Philip H.;
Helfrich, Wijnand;
Dierckx, Rudi A. J. O.;
van Waarde, Aren

Publication type:

Article

Rapid and efficient generation of antigen‐specific isogenic T cells from cryopreserved blood samples.

Published in:

Immunology & Cell Biology, 2022, v. 100, n. 4, p. 285, doi. 10.1111/imcb.12538

By:

Eerkens, Anneke L;
Vledder, Annegé;
van Rooij, Nienke;
Foijer, Floris;
Nijman, Hans W;
de Bruyn, Marco

Publication type:

Article

CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00007-0

By:

Vlaming, Martijn;
Bilemjian, Vrouyr;
Freile, Jimena Álvarez;
Lourens, Harm Jan;
van Rooij, Nienke;
Huls, Gerwin;
van Meerten, Tom;
de Bruyn, Marco;
Bremer, Edwin

Publication type:

Article

Genomic instability as a driver and suppressor of anti-tumor immunity.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1462496

By:

Requesens, Marta;
Foijer, Floris;
Nijman, Hans W.;
de Bruyn, Marco

Publication type:

Article

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3770, doi. 10.3390/ijms21113770

By:

Workel, Hagma H.;
van Rooij, Nienke;
Plat, Annechien;
Spierings, Diana C.J.;
Fehrmann, Rudolf S. N.;
Nijman, Hans W.;
de Bruyn, Marco

Publication type:

Article

EGFR-selective activation of CD27 co-stimulatory signaling by a bispecific antibody enhances anti-tumor activity of T cells.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1191866

By:

Melo, Vinicio;
Nelemans, Levi Collin;
Vlaming, Martijn;
Lourens, Harm Jan;
Wiersma, Valerie R.;
Bilemjian, Vrouyr;
Huls, Gerwin;
de Bruyn, Marco;
Bremer, Edwin

Publication type:

Article

Frequency of Th17 CD20+ cells in the peripheral blood of rheumatoid arthritis patients is higher compared to healthy subjects.

Published in:

Arthritis Research & Therapy, 2011, v. 13, n. 6, p. 3541, doi. 10.1186/ar3541

By:

Eggleton, Paul;
Bremer, Edwin;
Tarr, Joanna M.;
de Bruyn, Marco;
Helfrich, Wijnand;
Kendall, Alexandra;
Haigh, Richard C.;
Viner, Nick J.;
Winyard, Paul G.

Publication type:

Article

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.

Published in:

Autophagy, 2015, v. 11, n. 8, p. 1373, doi. 10.1080/15548627.2015.1063767

By:

Wiersma, Valerie R;
de Bruyn, Marco;
Wei, Yunwei;
van Ginkel, Robert J;
Hirashima, Mitsuomi;
Niki, Toshiro;
Nishi, Nozomu;
Zhou, Jin;
Pouwels, Simon D;
Samplonius, Douwe F;
Nijman, Hans W;
Eggleton, Paul;
Helfrich, Wijnand;
Bremer, Edwin

Publication type:

Article

The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells.

Published in:

Journal of Investigative Dermatology, 2012, v. 132, n. 9, p. 2302, doi. 10.1038/jid.2012.133

By:

Wiersma, Valerie R;
de Bruyn, Marco;
van Ginkel, Robert J;
Sigar, Emily;
Hirashima, Mitsuomi;
Niki, Toshiro;
Nishi, Nozomu;
Samplonius, Douwe F;
Helfrich, Wijnand;
Bremer, Edwin

Publication type:

Article

Potent Systemic Anticancer Activity of Adenovirally Expressed EGFR-Selective TRAIL Fusion Protein.

Published in:

Molecular Therapy, 2008, v. 16, n. 12, p. 1919, doi. 10.1038/mt.2008.203

By:

Bremer, Edwin;
van Dam, Gooitzen M.;
de Bruyn, Marco;
van Riezen, Manon;
Dijkstra, Marike;
Kamps, Gera;
Helfrich, Wijnand;
Haisma, Hidde

Publication type:

Article

Works by de Bruyn, Marco

Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer.

ImmunoPET provides a novel way to visualize the CD103<sup>+</sup> tissue-resident memory T cell to predict the response of immune checkpoint inhibitors.

Development of [<sup>89</sup>Zr]Zr-hCD103.Fab01A and [<sup>68</sup>Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET.

The Novel Immune Checkpoint GPR56 Is Expressed on Tumor-Infiltrating Lymphocytes and Selectively Upregulated upon TCR Signaling.

Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer.

Prognostic benefit of TILs independent of clinicopathological and molecular factors.

Tumour-infiltrating lymphocytes: from prognosis to treatment selection.

Carbon monoxide-Releasing Molecule-2 (CORM-2) attenuates acute hepatic ischemia reperfusion injury in rats.

Tumor infiltrating CD8/CD103/ TIM-3-expressing lymphocytes in epithelial ovarian cancer coexpress CXCL13 and associate with improved survival.

Targeted delivery of CD40L promotes restricted activation of antigen-presenting cells and induction of cancer cell death.

Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanomaoutgrowth in vitro and in vivo.

Targeted delivery of a designed sTRAIL mutant results in superior apoptotic activity towards EGFR-positive tumor cells.

B cells critical for outcome in high grade serous ovarian carcinoma.

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis.

Lymphadenectomy and Adjuvant Therapy Improve Survival with Uterine Carcinosarcoma: A Large Retrospective Cohort Study.

The ever-expanding immunomodulatory role of calreticulin in cancer immunity.

C-type lectin-like molecule-1 (CLL1)-targeted TRAIL augments the tumoricidal activity of granulocytes and potentiates therapeutic antibody-dependent cell-mediated cytotoxicity.

In Vivo Responses of Human A375M Melanoma to a σ Ligand: 18F-FDG PET Imaging.

Rapid and efficient generation of antigen‐specific isogenic T cells from cryopreserved blood samples.

CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties.

Genomic instability as a driver and suppressor of anti-tumor immunity.

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer.

EGFR-selective activation of CD27 co-stimulatory signaling by a bispecific antibody enhances anti-tumor activity of T cells.

Frequency of Th17 CD20+ cells in the peripheral blood of rheumatoid arthritis patients is higher compared to healthy subjects.

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.

The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells.

Potent Systemic Anticancer Activity of Adenovirally Expressed EGFR-Selective TRAIL Fusion Protein.