Works matching AU de Bono, J S

Results: 34

Assessing response in bone metastases in prostate cancer with diffusion weighted MRI.

Published in:

2011

By:

Messiou C;
Collins DJ;
Giles S;
de Bono JS;
Bianchini D;
de Souza NM;
Messiou, C;
Collins, D J;
Giles, S;
de Bono, J S;
Bianchini, D;
de Souza, N M

Publication type:

journal article

Phase I trial outcomes in older patients with advanced solid tumours.

Published in:

2016

By:

Khan, K H;
Yap, T A;
Ring, A;
Molife, L R;
Bodla, S;
Thomas, K;
Zivi, A;
Smith, A;
Judson, I;
Banerji, U;
de Bono, J S;
Kaye, S B

Publication type:

journal article

Complications of hyperglycaemia with PI3K-AKT-mTOR inhibitors in patients with advanced solid tumours on Phase I clinical trials.

Published in:

2015

By:

Geuna, E;
Roda, D;
Rafii, S;
Jimenez, B;
Capelan, M;
Rihawi, K;
Montemurro, F;
Yap, T A;
Kaye, S B;
De Bono, J S;
Molife, L R;
Banerji, U

Publication type:

journal article

Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents.

Published in:

British Journal of Cancer, 2015, v. 112, n. 7, p. 1166, doi. 10.1038/bjc.2015.63

By:

Crespo, M;
van Dalum, G;
Ferraldeschi, R;
Zafeiriou, Z;
Sideris, S;
Lorente, D;
Bianchini, D;
Rodrigues, D N;
Riisnaes, R;
Miranda, S;
Figueiredo, I;
Flohr, P;
Nowakowska, K;
de Bono, J S;
Terstappen, L W M M;
Attard, G

Publication type:

Article

The neutrophil-lymphocyte ratio and its utilisation for the management of cancer patients in early clinical trials.

Published in:

British Journal of Cancer, 2015, v. 112, n. 7, p. 1157, doi. 10.1038/bjc.2015.67

By:

Kumar, R;
Geuna, E;
Michalarea, V;
Guardascione, M;
Naumann, U;
Lorente, D;
Kaye, S B;
de Bono, J S

Publication type:

Article

Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents.

Published in:

2015

By:

Crespo, M;
van Dalum, G;
Ferraldeschi, R;
Zafeiriou, Z;
Sideris, S;
Lorente, D;
Bianchini, D;
Rodrigues, D N;
Riisnaes, R;
Miranda, S;
Figueiredo, I;
Flohr, P;
Nowakowska, K;
de Bono, J S;
Terstappen, L W M M;
Attard, G

Publication type:

journal article

The neutrophil-lymphocyte ratio and its utilisation for the management of cancer patients in early clinical trials.

Published in:

2015

By:

Kumar, R;
Geuna, E;
Michalarea, V;
Guardascione, M;
Naumann, U;
Lorente, D;
Kaye, S B;
de Bono, J S

Publication type:

Journal Article

Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail.

Published in:

British Journal of Cancer, 2014, v. 111, n. 5, p. 828, doi. 10.1038/bjc.2014.350

By:

Ong, M;
Carreira, S;
Goodall, J;
Mateo, J;
Figueiredo, I;
Rodrigues, D N;
Perkins, G;
Seed, G;
Yap, T A;
Attard, G;
de Bono, J S

Publication type:

Article

Reply: 'Comment on Anti-tumour activity of abiraterone and diethylstilboestrol when administered sequentially to men with castration-resistant prostate cancer'.

Published in:

British Journal of Cancer, 2014, v. 110, n. 1, p. 267, doi. 10.1038/bjc.2013.737

By:

Omlin, A;
Pezaro, C J;
Zaidi, S;
Lorente, D;
Mukherji, D;
Bianchini, D;
Ferraldeschi, R;
Sandhu, S;
Dearnaley, D;
Parker, C;
Van As, N;
de Bono, J S;
Attard, G

Publication type:

Article

Antitumour activity of abiraterone and diethylstilboestrol when administered sequentially to men with castration-resistant prostate cancer.

Published in:

British Journal of Cancer, 2013, v. 109, n. 5, p. 1079, doi. 10.1038/bjc.2013.446

By:

Omlin, A;
J Pezaro, C;
Zaidi, S;
Lorente, D;
Mukherji, D;
Bianchini, D;
Ferraldeschi, R;
Sandhu, S;
Dearnaley, D;
Parker, C;
Van As, N;
de Bono, J S;
Attard, G

Publication type:

Article

Sarcopenia and change in body composition following maximal androgen suppression with abiraterone in men with castration-resistant prostate cancer.

Published in:

British Journal of Cancer, 2013, v. 109, n. 2, p. 325, doi. 10.1038/bjc.2013.340

By:

Pezaro, C;
Mukherji, D;
Tunariu, N;
Cassidy, A M;
Omlin, A;
Bianchini, D;
Seed, G;
Reid, A H M;
Olmos, D;
de Bono, J S;
Attard, G

Publication type:

Article

Association of creatine kinase and skin toxicity in phase I trials of anticancer agents.

Published in:

British Journal of Cancer, 2012, v. 107, n. 11, p. 1797, doi. 10.1038/bjc.2012.482

By:

Moreno Garcia, V;
Thavasu, P;
Blanco Codesido, M;
Molife, L R;
Vitfell Pedersen, J;
Puglisi, M;
Basu, B;
Shah, K;
Iqbal, J;
de Bono, J S;
Kaye, S B;
Banerji, U

Publication type:

Article

First-in-man phase I trial of two schedules of the novel synthetic tetrahydroisoquinoline alkaloid PM00104 (Zalypsis) in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2012, v. 106, n. 8, p. 1379, doi. 10.1038/bjc.2012.99

By:

Yap, T A;
Cortes-Funes, H;
Shaw, H;
Rodriguez, R;
Olmos, D;
Lal, R;
Fong, P C;
Tan, D S;
Harris, D;
Capdevila, J;
Coronado, C;
Alfaro, V;
Soto-Matos, A;
Fernández-Teruel, C;
Siguero, M;
Tabernero, J M;
Paz-Ares, L;
de Bono, J S;
López-Martin, J A

Publication type:

Article

Targeting IGF-1R: throwing out the baby with the bathwater?

Published in:

2011

By:

Basu, B.;
Olmos, D.;
de Bono, J. S.

Publication type:

commentary

A retrospective analysis of clinical outcome of patients with chemo-refractory metastatic breast cancer treated in a single institution phase I unit.

Published in:

2010

By:

Brunetto, A. T.;
Sarker, D;
Papadatos-Pastos, D;
Fehrmann, R;
Kaye, S. B.;
Johnston, S;
Allen, M;
De Bono, J. S.;
Swanton, C

Publication type:

journal article

The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study.

Published in:

2010

By:

Molife, L. R.;
Fong, P. C.;
Paccagnella, L.;
Reid, A. H. M.;
Shaw, H. M.;
Vidal, L.;
Arkenau, H.-T.;
Karavasilis, V.;
Yap, T. A.;
Olmos, D.;
Spicer, J.;
Postel-Vinay, S.;
Yin, D.;
Lipton, A.;
Demers, L.;
Leitzel, K.;
Gualberto, A.;
de Bono, J. S

Publication type:

journal article

A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours.

Published in:

2010

By:

Lassen, U.;
Molife, L. R.;
Sorensen, M.;
Engelholm, S.-A.;
Vidal, L.;
Sinha, R.;
Penson, R. T.;
Buhl-Jensen, P.;
Crowley, E.;
Tjornelund, J.;
Knoblauch, P.;
de Bono, J. S.

Publication type:

journal article

Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer.

Published in:

2010

By:

Reid, A. H. M.;
Attard, G.;
Ambroisine, L.;
Fisher, G.;
Kovacs, G.;
Brewer, D.;
Clark, J.;
Flohr, P.;
Edwards, S.;
Berney, D. M.;
Foster, C. S.;
Fletcher, A.;
Gerald, W. L.;
Møller, H.;
Reuter, V. E.;
Scardino, P. T.;
Cuzick, J.;
de Bono, J. S.;
Cooper, C. S.;
Møller, H

Publication type:

journal article

CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer.

Published in:

British Journal of Cancer, 2009, v. 100, n. 5, p. 671, doi. 10.1038/sj.bjc.6604904

By:

Ang, J. E.;
Olmos, D.;
de Bono, J. S.

Publication type:

Article

Reply: Clinical outcome and prognostic factors for patients treated within a phase I study: the Royal Marsden Hospital Experience.

Published in:

2008

By:

Olmos, D;
Arkenau, H-T;
Ang, J E;
de Bono, J S;
Judson, I;
Kaye, S B

Publication type:

Letter

Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer.

Published in:

2008

By:

Attard, G;
Clark, J;
Ambroisine, L;
Mills, I G;
Fisher, G;
Flohr, P;
Reid, A;
Edwards, S;
Kovacs, G;
Berney, D;
Foster, C;
Massie, C E;
Fletcher, A;
De Bono, J S;
Scardino, P;
Cuzick, J;
Cooper, C S;
Transatlantic Prostate Group

Publication type:

journal article

Phase I pharmacokinetic and pharmacodynamic study of the prenyl transferase inhibitor AZD3409 in patients with advanced cancer.

Published in:

2008

By:

Appels, N. M. G. M.;
Bolijn, M. J.;
Chan, K.;
Stephens, T. C.;
Hoctin-Boes, G.;
Middleton, M.;
Beijnen, J. H.;
de Bono, J. S.;
Harris, A. L.;
Schellens, J. H. M.

Publication type:

journal article

A phase I trial of ispinesib, a kinesin spindle protein inhibitor, with docetaxel in patients with advanced solid tumours.

Published in:

2008

By:

Blagden, S. P.;
Molife, L. R.;
Seebaran, A.;
Payne, M.;
Reid, A. H. M.;
Protheroe, A. S.;
Vasist, L. S.;
Williams, D. D.;
Bowen, C.;
Kathman, S. J.;
Hodge, J. P.;
Dar, M. M.;
de Bono, J. S.;
Middleton, M. R.

Publication type:

journal article

A phase Ib study of pertuzumab, a recombinant humanised antibody to HER2, and docetaxel in patients with advanced solid tumours.

Published in:

2007

By:

Attard, G.;
Kitzen, J.;
Blagden, S. P.;
Fong, P. C.;
Pronk, L. C.;
Zhi, J.;
Zugmaier, G.;
Verweij, J.;
de Bono, J. S.;
de Jonge, M.

Publication type:

journal article

Improving the outcome of patients with castration-resistant prostate cancer through rational drug development.

Published in:

2006

By:

Attard, G.;
Sarker, D.;
Reid, A.;
Molife, R.;
Parker, C.;
de Bono, J. S.

Publication type:

journal article

Phase I and pharmacokinetic (PK) study of MAG-CPT (PNU 166148): a polymeric derivative of camptothecin (CPT).

Published in:

2004

By:

Bissett, D;
Cassidy, J;
de Bono, JS;
Muirhead, F;
Main, M;
Robson, L;
Fraier, D;
Magnè, ML;
Pellizzoni, C;
Porro, MG;
Spinelli, R;
Speed, W;
Twelves, C;
de Bono, J S;
Magnè, M L;
Porro, M G

Publication type:

journal article

Improving the outcome of salvage treatment for non-seminomatous germ cell tumours (NSGCT).

Published in:

British Journal of Cancer, 2000, v. 83, n. 4, p. 426, doi. 10.1054/bjoc.2000.1290

By:

Bono, J S de;
Paul, J;
Simpson, A;
Anthoney, A;
Kirk, D;
Underwood, M;
Graham, J;
Kaye, S B

Publication type:

Article

A first-in-human study of the anti-α5β1 integrin monoclonal antibody PF-04605412 administered intravenously to patients with advanced solid tumors.

Published in:

2014

By:

Mateo, J;
Berlin, J;
de Bono, J S;
Cohen, R B;
Keedy, V;
Mugundu, G;
Zhang, Lianglin;
Abbattista, A;
Davis, C;
Gallo Stampino, C;
Borghaei, H

Publication type:

journal article

Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects.

Published in:

Oncogene, 2015, v. 34, n. 14, p. 1745, doi. 10.1038/onc.2014.115

By:

Ferraldeschi, R;
Welti, J;
Luo, J;
Attard, G;
de Bono, J S

Publication type:

Article

Exploratory analysis of the visceral disease subgroup in a phase III study of abiraterone acetate in metastatic castration-resistant prostate cancer.

Published in:

Prostate Cancer & Prostatic Diseases, 2014, v. 17, n. 1, p. 34, doi. 10.1038/pcan.2013.41

By:

Goodman, O B;
Flaig, T W;
Molina, A;
Mulders, P F A;
Fizazi, K;
Suttmann, H;
Li, J;
Kheoh, T;
de Bono, J S;
Scher, H I

Publication type:

Article

From Darkness to Light With Biomarkers in Early Clinical Trials of Cancer Drugs.

Published in:

Clinical Pharmacology & Therapeutics, 2009, v. 85, n. 2, p. 131, doi. 10.1038/clpt.2008.223

By:

Carden, C. P.;
Banerji, U.;
Kaye, S. B.;
Workman, P.;
de Bono, J. S.

Publication type:

Article

Translating cancer research into targeted therapeutics.

Published in:

Nature, 2010, v. 467, n. 7315, p. 543, doi. 10.1038/nature09339

By:

de Bono, J. S.;
Ashworth, Alan

Publication type:

Article

Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial.

Published in:

Gene Therapy, 2008, v. 15, n. 12, p. 911, doi. 10.1038/gt.2008.21

By:

White, C. L.;
Twigger, K. R.;
Vidal, L.;
De Bono, J. S.;
Coffey, M.;
Heinemann, L.;
Morgan, R.;
Merrick, A.;
Errington, F.;
Vile, R. G.;
Melcher, A. A.;
Pandha, H. S.;
Harrington, K. J.

Publication type:

Article

Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer.

Published in:

Oncogene, 2008, v. 27, n. 3, p. 253, doi. 10.1038/sj.onc.1210640

By:

Attard, G.;
Clark, J.;
Ambroisine, L.;
Fisher, G.;
Kovacs, G.;
Flohr, P.;
Berney, D.;
Foster, C. S.;
Fletcher, A.;
Gerald, W. L.;
Moller, H.;
Reuter, V.;
De Bono, J. S.;
Scardino, P.;
Cuzick, J.;
Cooper, C. S.

Publication type:

Article