Works by de Bock, Charles E.

Results: 30

Optimized flow cytometric detection of transient receptor potential vanilloid-1 (TRPV1) in human hematological malignancies.

Published in:

2022

By:

Omari, Sofia A.;
Geraghty, Dominic P.;
Khalafallah, Alhossain A.;
Venkat, Pooja;
Shegog, Yvette M.;
Ragg, Scott J.;
de Bock, Charles E.;
Adams, Murray J.

Publication type:

journal article

Evaluating nuclear translocation of surface receptors: recommendations arising from analysis of CD44.

Published in:

Histochemistry & Cell Biology, 2020, v. 153, n. 2, p. 77, doi. 10.1007/s00418-019-01835-y

By:

Thorne, Rick F.;
Wang, Yan;
Zhang, Yan;
Jing, Xueli;
Zhang, Xu Dong;
de Bock, Charles E.;
Oliveira, Camila S.

Publication type:

Article

Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia.

Published in:

Pharmaceutics, 2021, v. 13, n. 10, p. 1681, doi. 10.3390/pharmaceutics13101681

By:

Connerty, Patrick;
Moles, Ernest;
de Bock, Charles E.;
Jayatilleke, Nisitha;
Smith, Jenny L.;
Meshinchi, Soheil;
Mayoh, Chelsea;
Kavallaris, Maria;
Lock, Richard B.

Publication type:

Article

FAT1 cadherin is multiply phosphorylated on its ectodomain but phosphorylation is not catalysed by the four-jointed homologue.

Published in:

FEBS Letters, 2014, v. 588, n. 18, p. 3511, doi. 10.1016/j.febslet.2014.08.014

By:

Sadeqzadeh, Elham;
de Bock, Charles E.;
O’Donnell, Maureen R.;
Timofeeva, Anna;
Burns, Gordon F.;
Thorne, Rick F.

Publication type:

Article

Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells.

Published in:

FEBS Journal, 2005, v. 272, n. 14, p. 3572, doi. 10.1111/j.1742-4658.2005.04778.x

By:

de Bock, Charles E.;
Zhen Lin;
Itoh, Takashi;
Morris, David;
Murrell, George;
Yao Wang

Publication type:

Article

Patient‐derived xenografts: Practical considerations for preclinical drug testing.

Published in:

HemaSphere, 2025, v. 9, n. 4, p. 1, doi. 10.1002/hem3.70133

By:

de Bock, Charles E.

Publication type:

Article

Mastering fate: Redistributing a pioneer protein to rewrite leukemia's script.

Published in:

HemaSphere, 2025, v. 9, n. 1, p. 1, doi. 10.1002/hem3.70084

By:

Huang, Yizhou;
de Bock, Charles E.

Publication type:

Article

Overcoming a T‐ALL order: A comprehensive study linking genomics to clinical outcomes.

Published in:

HemaSphere, 2024, v. 8, n. 10, p. 1, doi. 10.1002/hem3.70027

By:

Huang, Yizhou;
de Bock, Charles E.

Publication type:

Article

Less is more: Depleting myeloid‐biased HSCs to restore immune function.

Published in:

HemaSphere, 2024, v. 8, n. 7, p. 1, doi. 10.1002/hem3.125

By:

Kosasih, Hansen J.;
de Bock, Charles E.

Publication type:

Article

A new mouse model highlights the need for better JAK inhibitors in myeloproliferative neoplasms.

Published in:

HemaSphere, 2024, v. 8, n. 4, p. 1, doi. 10.1002/hem3.66

By:

de Bock, Charles E.

Publication type:

Article

A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax.

Published in:

HemaSphere, 2024, v. 8, n. 2, p. 1, doi. 10.1002/hem3.1

By:

Kosasih, Hansen J.;
Healey, Gerry;
Brennan, Margs S.;
Bjelosevic, Stefan;
Sadras, Teresa;
Jalud, Fatimah B.;
Ibnat, Tasnia;
Ng, Ashley P.;
Mayoh, Chelsea;
Mao, Jie;
Tax, Gabor;
Ludlow, Louise E. A.;
Johnstone, Ricky W.;
Herold, Marco J.;
Khaw, Seong L.;
de Bock, Charles E.;
Ekert, Paul G.

Publication type:

Article

The Promise of Single‐cell Technology in Providing New Insights Into the Molecular Heterogeneity and Management of Acute Lymphoblastic Leukemia.

Published in:

HemaSphere, 2022, v. 6, n. 6, p. e734, doi. 10.1097/HS9.0000000000000734

By:

Pearson, Holly C.L.;
Hunt, Kooper V.;
Trahair, Toby N.;
Lock, Richard B.;
Lee, Heather J.;
de Bock, Charles E.

Publication type:

Article

Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice.

Published in:

European Journal of Immunology, 2018, v. 48, n. 10, p. 1728, doi. 10.1002/eji.201847597

By:

Baens, Mathijs;
Stirparo, Rocco;
Lampi, Youlia;
Verbeke, Delphine;
Vandepoel, Roel;
Cools, Jan;
Marynen, Peter;
de Bock, Charles E.;
Bornschein, Simon

Publication type:

Article

SIX6 is a TAL1-regulated transcription factor in T-ALL and associated with inferior outcome.

Published in:

Leukemia & Lymphoma, 2020, v. 61, n. 13, p. 3089, doi. 10.1080/10428194.2020.1804560

By:

Laukkanen, Saara;
Oksa, Laura;
Nikkilä, Atte;
Lahnalampi, Mari;
Parikka, Mataleena;
Seki, Masafumi;
Takita, Junko;
Degerman, Sofie;
de Bock, Charles E.;
Heinäniemi, Merja;
Lohi, Olli

Publication type:

Article

Transcriptional Interference Regulates the Evolutionary Development of Speech.

Published in:

Genes, 2022, v. 13, n. 7, p. 1195, doi. 10.3390/genes13071195

By:

Mortlock, Douglas P.;
Fang, Zhi-Ming;
Chandler, Kelly J.;
Hou, Yue;
Bickford, Lissett R.;
de Bock, Charles E.;
Eapen, Valsamma;
Clarke, Raymond A.

Publication type:

Article

The tumor suppressor Fat1 is dispensable for normal murine hematopoiesis.

Published in:

Journal of Leukocyte Biology, 2024, v. 116, n. 4, p. 909, doi. 10.1093/jleuko/qiae128

By:

Zhang, Qing;
Li, Meng Ke;
Hu, Xin Yuan;
Wu, Yu Xin;
Wang, Ying Ying;
Zhao, Pan Pan;
Cheng, Lin Na;
Yu, Rong Hua;
Zhang, Xu Dong;
Chen, Song;
Zhu, Zun Min;
Bock, Charles E de;
Thorne, Rick F

Publication type:

Article

Fat1 cadherin provides a novel minimal residual disease marker in acute lymphoblastic leukemia.

Published in:

Hematology, 2013, v. 18, n. 6, p. 315, doi. 10.1179/1607845413Y.0000000080

By:

Ardjmand, Alireza;
de Bock, Charles E.;
Shahrokhi, Somayeh;
Lincz, Lisa F.;
Boyd, Andrew W.;
Burns, Gordon F.;
Thorne, Rick F.

Publication type:

Article

Long Non-coding RNAs: Major Regulators of Cell Stress in Cancer.

Published in:

Frontiers in Oncology, 2020, p. 1, doi. 10.3389/fonc.2020.00285

By:

Connerty, Patrick;
Lock, Richard B.;
de Bock, Charles E.

Publication type:

Article

Gene expression changes in SNAP-stimulated and iNOS-transfected tenocytes-expression of extracellular matrix genes and its implications for tendon-healing.

Published in:

Journal of Orthopaedic Research, 2006, v. 24, n. 9, p. 1869, doi. 10.1002/jor.20237

By:

Molloy, Timothy J.;
de Bock, Charles E.;
Wang, Yao;
Murrell, George A.C.

Publication type:

Article

FAT1 functions as an oncogenic driver in triple negative breast cancer through AKT pathway-driven effects on the matrisome.

Published in:

International Journal of Biological Sciences, 2025, v. 21, n. 5, p. 2201, doi. 10.7150/ijbs.104921

By:

Panpan Zhao;
Yuanyuan Zhang;
Yang Yu;
Qing Zhang;
Xiaoying Liu;
Xu Dong Zhang;
Song Chen;
de Bock, Charles E.;
Thorne, Rick F.;
Yujie Shi

Publication type:

Article

Mutations in GDF6 are associated with vertebral segmentation defects in Klippel-Feil syndrome.

Published in:

Human Mutation, 2008, v. 29, n. 8, p. 1017, doi. 10.1002/humu.20741

By:

Tassabehji, May;
Fang, Zhi Ming;
Hilton, Emma N.;
McGaughran, Julie;
Zhao, Zhongming;
de Bock, Charles E.;
Howard, Emma;
Malass, Michael;
Donnai, Dian;
Diwan, Ashish;
Manson, Forbes D.C.;
Murrell, Dédée;
Clarke, Raymond A.

Publication type:

Article

PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma.

Published in:

Nature Communications, 2013, v. 4, n. 2, p. 1508, doi. 10.1038/ncomms2489

By:

Ye, Yan;
Jin, Lei;
Wilmott, James S.;
Hu, Wang Lai;
Yosufi, Benafsha;
Thorne, Rick F.;
Liu, Tao;
Rizos, Helen;
Yan, Xu Guang;
Dong, Li;
Tay, Kwang Hong;
Tseng, Hsin-Yi;
Guo, Su Tang;
de Bock, Charles E.;
Jiang, Chen Chen;
Wang, Chun Yan;
Wu, Mian;
Zhang, Lin Jie;
Hersey, Peter;
Scolyer, Richard A.

Publication type:

Article

Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-630

By:

Oliveira, Camila S.;
de Bock, Charles E.;
Molloy, Timothy J.;
Sadeqzadeh, Elham;
Xin Yan Geng;
Hersey, Peter;
Xu Dong Zhang;
Thorne, Rick F.

Publication type:

Article

Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma.

Published in:

2014

By:

Oliveira, Camila S;
de Bock, Charles E;
Molloy, Timothy J;
Sadeqzadeh, Elham;
Geng, Xin Yan;
Hersey, Peter;
Zhang, Xu Dong;
Thorne, Rick F

Publication type:

journal article

The landscape of alterations affecting epigenetic regulators in T‐cell acute lymphoblastic leukemia: Roles in leukemogenesis and therapeutic opportunities.

Published in:

International Journal of Cancer, 2024, v. 154, n. 9, p. 1522, doi. 10.1002/ijc.34819

By:

Walia, Yashna;
de Bock, Charles E.;
Huang, Yizhou

Publication type:

Article

A Soluble Form of the Giant Cadherin Fat1 Is Released from Pancreatic Cancer Cells by ADAM10 Mediated Ectodomain Shedding.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090461

By:

Wojtalewicz, Nathalie;
Sadeqzadeh, Elham;
Weiß, Jakob V.;
Tehrani, Mahnaz Moradian;
Klein-Scory, Susanne;
Hahn, Stephan;
Schmiegel, Wolff;
Warnken, Uwe;
Schnölzer, Martina;
de Bock, Charles E.;
Thorne, Rick F.;
Schwarte-Waldhoff, Irmgard

Publication type:

Article

JAK3 mutations and HOXA9 expression are important cooperating events in T-cell acute lymphoblastic leukemia.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 5, p. 1, doi. 10.1080/23723556.2018.1458014

By:

de Bock, Charles E.;
Cools, Jan

Publication type:

Article

JAK3 mutations and HOXA9 expression are important cooperating events in T-cell acute lymphoblastic leukemia.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 3, p. 1, doi. 10.1080/23723556.2018.1458014

By:

de Bock, Charles E.;
Cools, Jan

Publication type:

Article

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.

Published in:

Science Translational Medicine, 2019, v. 11, n. 494, p. 1, doi. 10.1126/scitranslmed.aau6246

By:

Habets, Roger A.;
de Bock, Charles E.;
Serneels, Lutgarde;
Lodewijckx, Inge;
Verbeke, Delphine;
Nittner, David;
Narlawar, Rajeshwar;
Demeyer, Sofie;
Dooley, James;
Liston, Adrian;
Taghon, Tom;
Cools, Jan;
de Strooper, Bart

Publication type:

Article

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models.

Published in:

Journal of Hematology & Oncology, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13045-018-0650-0

By:

Vicente, Carmen;
Stirparo, Rocco;
Demeyer, Sofie;
de Bock, Charles E.;
Gielen, Olga;
Atkins, Mardelle;
Yan, Jiekun;
Halder, Georg;
Hassan, Bassem A.;
Cools, Jan

Publication type:

Article