Works by da Silva Xavier, Gabriela

Results: 26

Beta cell lipotoxicity in the development of type 2 diabetes: the need for species-specific understanding.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1275835

By:

Thomas, Patricia;
Gallagher, Meurig T.;
Xavier, Gabriela Da Silva

Publication type:

Article

Editorial: The pancreatic islet -- a multifaceted hub of inter-cellular communication.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1182897

By:

Quan Zhang;
Huising, Mark O.;
Da Silva Xavier, Gabriela;
Hauge-Evans, Astrid C.

Publication type:

Article

Análise qualitativa de conteúdo do guia de gestão da coleção para bibliotecas públicas.

Published in:

Prisma.com, 2020, n. 44, p. 73, doi. 10.21747/16463153/44a4

By:

Xavier da Silva, Gabriela

Publication type:

Article

25 de Abril Sempre! Portuguese Science and the 50th anniversary of the Carnation Revolution.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06229-y

By:

Dantas, Tiago;
Abreu, Carla M. C.;
De-Castro, Maria J. G.;
Grosso, Ana Rita;
de Sousa Valente, Joao;
da Silva Xavier, Gabriela

Publication type:

Article

Convolutional neural networks for reconstruction of undersampled optical projection tomography data applied to in vivo imaging of zebrafish.

Published in:

Journal of Biophotonics, 2019, v. 12, n. 12, p. N.PAG, doi. 10.1002/jbio.201900128

By:

Davis, Samuel P. X.;
Kumar, Sunil;
Alexandrov, Yuriy;
Bhargava, Ajay;
da Silva Xavier, Gabriela;
Rutter, Guy A.;
Frankel, Paul;
Sahai, Erik;
Flaxman, Seth;
French, Paul M. W.;
McGinty, James

Publication type:

Article

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice.

Published in:

Diabetologia, 2021, v. 64, n. 1, p. 129, doi. 10.1007/s00125-020-05292-4

By:

Nguyen-Tu, Marie-Sophie;
Martinez-Sanchez, Aida;
Leclerc, Isabelle;
Rutter, Guy A.;
da Silva Xavier, Gabriela

Publication type:

Article

The pore-forming subunit MCU of the mitochondrial Ca2+ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.

Published in:

Diabetologia, 2020, v. 63, n. 7, p. 1368, doi. 10.1007/s00125-020-05148-x

By:

Georgiadou, Eleni;
Haythorne, Elizabeth;
Dickerson, Matthew T.;
Lopez-Noriega, Livia;
Pullen, Timothy J.;
da Silva Xavier, Gabriela;
Davis, Samuel P. X.;
Martinez-Sanchez, Aida;
Semplici, Francesca;
Rizzuto, Rosario;
McGinty, James A.;
French, Paul M.;
Cane, Matthew C.;
Jacobson, David A.;
Leclerc, Isabelle;
Rutter, Guy A.

Publication type:

Article

Animal Models of GWAS-Identified Type 2 Diabetes Genes.

Published in:

Journal of Diabetes Research, 2013, p. 1, doi. 10.1155/2013/906590

By:

da Silva Xavier, Gabriela;
Bellomo, Elisa A.;
McGinty, James A.;
French, Paul M.;
Rutter, Guy A.

Publication type:

Article

The Cells of the Islets of Langerhans.

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 3, p. 54, doi. 10.3390/jcm7030054

By:

Da Silva Xavier, Gabriela

Publication type:

Article

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 5, p. 1390, doi. 10.1093/hmg/ddu553

By:

Mitchell, Ryan K.;
Mondragon, Angeles;
Chen, Lingling;
Mcginty, James A.;
French, Paul M.;
Ferrer, Jorge;
Thorens, Bernard;
Hodson, David J.;
Rutter, Guy A.;
Da Silva Xavier, Gabriela

Publication type:

Article

Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 3, p. 814, doi. 10.1093/hmg/ddu499

By:

Zatyka, Malgorzata;
Da Silva Xavier, Gabriela;
Bellomo, Elisa A.;
Leadbeater, Wendy;
Astuti, Dewi;
Smith, Joel;
Michelangeli, Frank;
Rutter, Guy A.;
Barrett, Timothy G.

Publication type:

Article

Sodium-potassium ATPase β1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 2, p. 190

By:

Zatyka, Malgorzata;
Ricketts, Christopher;
da Silva Xavier, Gabriela;
Minton, Jayne;
Fenton, Sarah;
Hofmann-Thiel, Sabine;
Rutter, Guy A;
Barrett, Timothy G.

Publication type:

Article

Divergent Effects of Liraglutide, Exendin-4, and Sitagliptin on Beta-Cell Mass and Indicators of Pancreatitis in a Mouse Model of Hyperglycaemia.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104873

By:

Mondragon, Angeles;
Davidsson, Daniel;
Kyriakoudi, Styliana;
Bertling, Annika;
Gomes-Faria, Rosa;
Cohen, Patrizia;
Rothery, Stephen;
Chabosseau, Pauline;
Rutter, Guy A.;
da Silva Xavier, Gabriela

Publication type:

Article

Sulfation pathways in the maintenance of functional beta-cell mass and implications for diabetes.

Published in:

Essays in Biochemistry, 2024, v. 68, n. 4, p. 509, doi. 10.1042/EBC20240034

By:

Mueller, Jonathan Wolf;
Thomas, Patricia;
Dalgaard, Louise Torp;
da Silva Xavier, Gabriela

Publication type:

Article

ATP depletion inhibits Ca<sup>2+</sup> release, influx and extrusion in pancreatic acinar cells but not pathological Ca<sup>2+</sup> responses induced by bile.

Published in:

Pflügers Archiv: European Journal of Physiology, 2008, v. 455, n. 6, p. 1025, doi. 10.1007/s00424-007-0360-x

By:

Barrow, Stephanie L.;
Voronina, Svetlana G.;
da Silva Xavier, Gabriela;
Chvanov, Misha A.;
Longbottom, Rebecca E.;
Gerasimenko, Oleg V.;
Petersen, Ole H.;
Rutter, Guy A.;
Tepikin, Alexei V.

Publication type:

Article

What is the value of teaching basic science as part of the medical curriculum?

Published in:

Discover Education, 2025, v. 4, n. 1, p. 1, doi. 10.1007/s44217-025-00487-6

By:

da Silva Xavier, Gabriela;
Ntonia, Iro

Publication type:

Article

Glucagon‐like peptide‐1 analogues in monogenic syndromic obesity: Real‐world data from a large cohort of Alström syndrome patients.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 3, p. 989, doi. 10.1111/dom.15398

By:

Ali, Sadaf;
Baig, Shanat;
Wanninayake, Subadra;
da Silva Xavier, Gabriela;
Dawson, Charlotte;
Paisey, Richard;
Geberhiwot, Tarekegn

Publication type:

Article

miR-29a and miR-29b Contribute to Pancreatic β-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1).

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 15, p. 3182, doi. 10.1128/MCB.01433-10

By:

Pullen, Timothy J.;
Xavier, Gabriela da Silva;
Kelsey, Gavin;
Rutter, Guy A.

Publication type:

Article

Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells.

Published in:

2010

By:

Noordeen NA;
Khera TK;
Sun G;
Longbottom ER;
Pullen TJ;
da Silva Xavier G;
Rutter GA;
Leclerc I;
Noordeen, Nafeesa A;
Khera, Tarnjit K;
Sun, Gao;
Longbottom, E Rebecca;
Pullen, Timothy J;
da Silva Xavier, Gabriela;
Rutter, Guy A;
Leclerc, Isabelle

Publication type:

journal article

Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells.

Published in:

Diabetes, 2010, v. 59, n. 1, p. 153, doi. 10.2337/db08-0868

By:

Noordeen, Nafeesa A.;
Khera, Tarnjit K.;
Sun, Gao;
Longbottom, E. Rebecca;
Pullen, Timothy J.;
Xavier, Gabriela da Silva;
Rutter, Guy A.;
Leclerc, Isabelle

Publication type:

Article

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants.

Published in:

Diabetes, 2009, v. 58, n. 9, p. 2070, doi. 10.2337/db09-0551

By:

Nicolson, Tamara J.;
Bellomo, Elisa A.;
Wijesekara, Nadeeja;
Loder, Merewyn K.;
Baldwin, Jocelyn M.;
Gyulkhandanyan, Armen V.;
Koshkin, Vasilij;
Tarasov, Andrei I.;
Carzaniga, Raffaella;
Kronenberger, Katrin;
Taneja, Tarvinder K.;
da Silva Xavier, Gabriela;
Libert, Sarah;
Froguel, Philippe;
Scharfmann, Raphael;
Stetsyuk, Volodymir;
Ravassard, Philippe;
Parker, Helen;
Gribble, Fiona M.;
Reimann, Frank

Publication type:

Article

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.

Published in:

2009

By:

da Silva Xavier G;
Loder MK;
McDonald A;
Tarasov AI;
Carzaniga R;
Kronenberger K;
Barg S;
Rutter GA;
da Silva Xavier, Gabriela;
Loder, Merewyn K;
McDonald, Angela;
Tarasov, Andrei I;
Carzaniga, Raffaella;
Kronenberger, Katrin;
Barg, Sebastian;
Rutter, Guy A

Publication type:

journal article

TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells.

Published in:

Diabetes, 2009, v. 58, n. 4, p. 894, doi. 10.2337/db08-1187

By:

Xavier, Gabriela da Silva;
Loder, Merewyn K.;
McDonald, Angela;
Tarasov, Andrei I.;
Carzaniga, Raffaella;
Kronenberger, Katrin;
Barg, Sebastian;
Rutter, Guy A.

Publication type:

Article

Tcf712 Regulates Glucose-Stimulated Insulin Secretion and insulin Gene Expression in Min6 β-Cells.

Published in:

Diabetes, 2007, v. 56, p. A437

By:

Xavier, Gabriela Da Silva;
Rutter, Guy A.

Publication type:

Article

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells.

Published in:

2002

By:

Andreolas, Chrysovalantis;
da Silva Xavier, Gabriela;
Diraison, Frederique;
Chao Zhao;
Zhao, Chao;
Varadi, Aniko;
Lopez-Casillas, Fernando;
Ferré, Pascal;
Foufelle, Fabienne;
Rutter, Guy A.;
Ferré, Pascal

Publication type:

journal article

Neuronatin regulates pancreatic β cell insulin content and secretion.

Published in:

2018

By:

Millership, Steven J.;
Da Silva Xavier, Gabriela;
Choudhury, Agharul I.;
Bertazzo, Sergio;
Chabosseau, Pauline;
Pedroni, Silvia M. A.;
Irvine, Elaine E.;
Montoya, Alex;
Faull, Peter;
Taylor, William R.;
Kerr-Conte, Julie;
Pattou, Francois;
Ferrer, Jorge;
Christian, Mark;
John, Rosalind M.;
Latreille, Mathieu;
Ming Liu;
Rutter, Guy A.;
Scott, James;
Withers, Dominic J.

Publication type:

journal article