Works by da Rocha, Matheus Nunes

Results: 26

Virtual Screening of Citrus Flavonoid Tangeretin: A Promising Pharmacological Tool for the Treatment and Prevention of Zika fever and COVID-19.

Published in:

Journal of Computational Biophysics & Chemistry, 2021, v. 20, n. 3, p. 283, doi. 10.1142/S2737416521500137

By:

Rocha, Matheus Nunes da;
Alves, Daniela Ribeiro;
Marinho, Marcia Machado;
Morais, Selene Maia de;
Marinho, Emmanuel Silva

Publication type:

Article

Virtual Screening of Natural Curcumins and Related Compounds Against SARS-CoV-2.

Published in:

Journal of Computational Biophysics & Chemistry, 2021, v. 20, n. 1, p. 53, doi. 10.1142/S2737416521500046

By:

Alves, Daniela Ribeiro;
da Rocha, Matheus Nunes;
de Sousa, Damião Sampaio;
Oliveira, Iris Cristina Maia;
Marinho, Marcia Machado;
de Morais, Selene Maia;
Marinho, Emmanuel Silva

Publication type:

Article

Antibacterial and Inhibitory Activity of Nora and Mepa Efflux Pumps of Estragole Complexed to β-Cyclodextrin (ES/β-CD) In Vitro Against Staphylococcus aureus Bacteria, Molecular Docking and MPO-Based Pharmacokinetics Prediction.

Published in:

Pharmaceutics, 2024, v. 16, n. 11, p. 1469, doi. 10.3390/pharmaceutics16111469

By:

Costa, Roger Henrique Sousa da;
Pessoa, Renata Torres;
Silva, Eduardo dos Santos;
Araujo, Isaac Moura;
Gonçalves, Sheila Alves;
Rocha, Janaína Esmeraldo;
Pereira Junior, Francisco Nascimento;
Oliveira, Naiara Cipriano;
Oliveira, Victor Moreira de;
Rocha, Matheus Nunes da;
Marinho, Emmanuel Silva;
Kelly Gomes de Carvalho, Natália;
Galberto Martins da Costa, José;
Santos, Hélcio Silva dos;
Menezes, Irwin Rose Alencar de

Publication type:

Article

Evaluation of Emulsification Techniques to Optimize the Properties of Chalcone Nanoemulsions for Antifungal Applications.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 11, p. 1442, doi. 10.3390/ph17111442

By:

Nascimento, Joice Farias do;
Abreu, Flavia Oliveira Monteiro da Silva;
Holanda, Taysse;
Oliveira dos Santos Fontenelle, Raquel;
Prado, Júlio César Sousa;
Marinho, Emmanuel Silva;
da Rocha, Matheus Nunes;
Guedes, Jesyka Macêdo;
Cavalcanti, Bruno Coelho;
Ribeiro, Wesley Lyeverton Correia;
Marinho, Márcia Machado;
Santos, Helcio Silva dos

Publication type:

Article

In Silico Study in MPO and Molecular Docking of the Synthetic Drynaran Analogues Against the Chronic Tinnitus: Modulation of the M1 Muscarinic Acetylcholine Receptor.

Published in:

Molecular Biotechnology, 2024, v. 66, n. 2, p. 254, doi. 10.1007/s12033-023-00748-5

By:

da Rocha, Matheus Nunes;
da Fonseca, Aluísio Marques;
Dantas, Adriana Nogueira Machado;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Gabrielle Silva

Publication type:

Article

Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach.

Published in:

Future Journal of Pharmaceutical Sciences, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s43094-025-00783-w

By:

Silva, Jacilene;
da Rocha, Matheus Nunes;
de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
Lúcio, Francisco Nithael Melo;
Marinho, Márcia Machado;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Robinin Isolated From Solanum Asperum Exhibits Pharmacological Actions in the Central Nervous System of Adult Zebrafish (Danio rerio).

Published in:

Chemistry & Biodiversity, 2025, v. 22, n. 5, p. 1, doi. 10.1002/cbdv.202402173

By:

Lemos, Cecília Guimarães;
Wlisses da Silva, Antonio;
Maciel, Jéssica Bezerra;
Ferreira, Maria Kueirislene Amâncio;
Nunes da Rocha, Matheus;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
Pinto, Francisco das Chagas Lima;
Loiola, Otília Deusdênia;
de Castro Gomes, Andreia Ferreira;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Polyphenols of four medicinal plant extracts and relation with antifungal activities through in vitro and in silico studies.

Published in:

Revista Ciência e Natura, 2024, v. 46, p. 1, doi. 10.5902/2179460X76669

By:

da Silva Lopes, Francisco Flávio;
Soares Frota, Lucas;
Maria Neves, Andréa;
Oliveira Lima, Cecília Lara;
Ferreira da Silva, Marcus Vinícius;
Nunes da Rocha, Matheus;
Machado Marinho, Marcia;
dos Santos Fontenellem, Raquel Oliveira;
Silva Marinho, Emmanuel;
Maia Morais, Selene

Publication type:

Article

Insights of potential trypanocidal effect of the synthetic derivative (2E)-1-(4-aminophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one: in vitro assay, MEV analysis, quantum study, molecular docking, molecular dynamics, MPO analysis, and predictive ADMET.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 10, p. 7797, doi. 10.1007/s00210-024-03138-z

By:

Marinho, Márcia Machado;
da Rocha, Matheus Nunes;
Magalhães, Emanuel Paula;
Ribeiro, Lyanna Rodrigues;
Roberto, Caio Henrique Alexandre;
de Queiroz Almeida-Neto, Francisco Wagner;
Monteiro, Marília Lopes;
Nunes, João Victor Serra;
de Menezes, Ramon Róseo Paula Pessoa Bezerra;
Marinho, Emmanuel Silva;
de Lima Neto, Pedro;
Martins, Alice Maria Costa;
dos Santos, Hélcio Silva

Publication type:

Article

Synthesis, molecular docking, ADMET, and evaluation of the anxiolytic effect in adult zebrafish of synthetic chalcone (E)‐3‐(4‐(dimethylamino)phenyl)‐1‐(2‐hydroxyphenyl)prop‐2‐en‐1‐one: An in vivo and in silico approach

Published in:

Fundamental & Clinical Pharmacology, 2024, v. 38, n. 2, p. 290, doi. 10.1111/fcp.12960

By:

Santos Oliveira, Larissa;
Kueirislene Amâncio Ferreira, Maria;
Wagner de Queiroz Almeida‐Neto, Francisco;
Wlisses da Silva, Antonio;
Ivo Lima Pinto Filho, José;
Nunes da Rocha, Matheus;
Machado Marinho, Emanuelle;
Henrique Ferreira Ribeiro, Walber;
Machado Marinho, Márcia;
Silva Marinho, Emmanuel;
Eire Silva Alencar de Menezes, Jane;
dos Santos, Hélcio Silva

Publication type:

Article

Structure and Ligand Based Virtual Screening and MPO Topological Analysis of Triazolo Thiadiazepine-fused Coumarin Derivatives as Anti-Parkinson Drug Candidates.

Published in:

Molecular Biotechnology, 2025, v. 67, n. 6, p. 2339, doi. 10.1007/s12033-024-01200-y

By:

Pereira, Antônio Mateus Gomes;
de Oliveira, Victor Moreira;
da Rocha, Matheus Nunes;
Roberto, Caio Henrique Alexandre;
Cajazeiras, Francisco Ferdinando Mesquita;
Guedes, Jesyka Macêdo;
Marinho, Márcia Machado;
Teixeira, Alexandre Magno Rodrigues;
Marinho, Emmanuel Silva;
de Lima-Neto, Pedro;
dos Santos, Hélcio Silva

Publication type:

Article

Ligand and structure-based virtual screening approaches in drug discovery: minireview.

Published in:

Molecular Diversity, 2025, v. 29, n. 3, p. 2799, doi. 10.1007/s11030-024-10979-6

By:

da Rocha, Matheus Nunes;
de Sousa, Damião Sampaio;
da Silva Mendes, Francisco Rogenio;
dos Santos, Helcio Silva;
Marinho, Gabrielle Silva;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva

Publication type:

Article

Antitrypanosomal Potential of Chalcone‐Based Ursolic Acid Derivatives via Ligand‐Based Virtual Screening, DMPK Analyses, Molecular Dynamics Simulation, and MM/GBSA Binding Energy.

Published in:

ChemistrySelect, 2024, v. 9, n. 44, p. 1, doi. 10.1002/slct.202402673

By:

Nunes, João Victor Serra;
da Rocha, Matheus Nunes;
de de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva;
Marinho, Márcia Machado;
Martins, Alice Maria Costa

Publication type:

Article

Structure-based virtual screening of mangiferin derivatives with antidiabetic action: a molecular docking and dynamics study and MPO-based drug-likeness approach.

Published in:

3 Biotech, 2024, v. 14, n. 5, p. 1, doi. 10.1007/s13205-024-03978-9

By:

da Silva Lopes, Francisco Flávio;
Lúcio, Francisco Nithael Melo;
da Rocha, Matheus Nunes;
de Oliveira, Victor Moreira;
Roberto, Caio Henrique Alexandre;
Marinho, Márcia Machado;
Marinho, Emmanuel Silva;
de Morais, Selene Maia

Publication type:

Article

De novo design of bioactive phenol and chromone derivatives for inhibitors of Spike glycoprotein of SARS-CoV-2 in silico.

Published in:

3 Biotech, 2023, v. 13, n. 9, p. 1, doi. 10.1007/s13205-023-03695-9

By:

Lima, Joan Petrus Oliveira;
da Fonseca, Aluísio Marques;
Marinho, Gabrielle Silva;
da Rocha, Matheus Nunes;
Marinho, Emanuelle Machado;
dos Santos, Helcio Silva;
Freire, Rafael Melo;
Marinho, Emmanuel Silva;
de Lima-Neto, Pedro;
Fechine, Pierre Basílio Almeida

Publication type:

Article

Heterocyclic chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(thiophen-2-yl) prop-2-en-1-one derived from a natural product with antinociceptive, anti-inflammatory, and hypoglycemic effect in adult zebrafish.

Published in:

3 Biotech, 2023, v. 13, n. 8, p. 1, doi. 10.1007/s13205-023-03696-8

By:

Ferreira, Maria Kueirislene Amancio;
Freitas, Wendy Pascoal Oliveira;
Barbosa, Italo Moura;
da Rocha, Matheus Nunes;
da Silva, Antônio Wlisses;
de Lima Rebouças, Emanuela;
da Silva Mendes, Francisco Rogênio;
Alves, Carlucio Roberto;
Nunes, Paulo Iury Gomes;
Marinho, Márcia Machado;
Furtado, Roselayne Ferro;
Santos, Flávia Almeida;
Marinho, Emmanuel Silva;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Helcio Silva

Publication type:

Article

Synthesis, structural, characterization, antibacterial and antibiotic modifying activity, ADMET study, molecular docking and dynamics of chalcone (E)-1-(4-aminophenyl)-3-(4-nitrophenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 4, p. 1670, doi. 10.1080/07391102.2023.2213777

By:

Souza, Mikael Amaro de;
Rodrigues, Leilane Gomes;
Rocha, Janaina Esmeraldo;
de Freitas, Thiago Sampaio;
Bandeira, Paulo Nogueira;
Marinho, Márcia Machado;
Nunes da Rocha, Matheus;
Marinho, Emmanuel Silva;
Honorato Barreto, Antonio Cesar;
Coutinho, Henrique Douglas Melo;
Silva, Lorena Mara Alexandre;
Julião, Murilo Sergio da Silva;
Marques Canuto, Kirley;
Marques da Fonseca, Aluísio;
Teixeira, Alexandre Magno Rodrigues;
dos Santos, Hélcio Silva

Publication type:

Article

Isolation, characterization and in silico study of propenamide alkaloids from Hymenoepmecis bicolor poison against active μ-opioid receptor.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 24, p. 14621, doi. 10.1080/07391102.2023.2183043

By:

Marques da Fonseca, Aluísio;
Freire da Silva, Ananias;
Barbosa da Silva, Francisco Lennon;
Caluaco, Bernardino Joaquim;
Gaieta, Eduardo Menezes;
Nunes da Rocha, Matheus;
Colares, Regilany Paulo;
Sobczak, Jober Fernando;
Marinho, Gabrielle Silva;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

GABA<sub>A</sub> and serotonergic receptors participation in anxiolytic effect of chalcones in adult zebrafish.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 12426, doi. 10.1080/07391102.2023.2167116

By:

Mendes, Francisco Rogênio Silva;
da Silva, Antonio Wlisses;
Ferreira, Maria Kueirislene Amâncio;
Rebouças, Emanuela de Lima;
Moura Barbosa, Italo;
da Rocha, Matheus Nunes;
Henrique Ferreira Ribeiro, Walber;
Menezes, Ramon Róseo Paula Pessoa Bezerra de;
Magalhães, Emanuel Paula;
Marinho, Emanuelle Machado;
Marinho, Márcia Machado;
Bandeira, Paulo Nogueira;
de Menezes, Jane Eire Silva Alencar;
Marinho, Emmanuel Silva;
dos Santos, Hélcio Silva

Publication type:

Article

Naphthoquinones biflorin and bis-biflorin (Capraria biflora) as possible inhibitors of the fungus Candida auris polymerase: molecular docking, molecular dynamics, MM/GBSA calculations and in silico drug-likeness study.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 11564, doi. 10.1080/07391102.2022.2163702

By:

da Fonseca, Aluísio Marques;
Soares, Neidelenio Baltazar;
Colares, Regilany Paulo;
Macedo de Oliveira, Mauro;
Santos Oliveira, Larissa;
Marinho, Gabrielle Silva;
Raya Paula de Lima, Mira;
da Rocha, Matheus Nunes;
dos Santos, Hélcio Silva;
Marinho, Emmanuel Silva

Publication type:

Article

Antichagasic evaluation, molecular docking and ADMET properties of the chalcone (2E)-3-(2-fluorophenyl)-1-(2-hydroxy- 3,4,6-trimethoxyphenyl)prop-2-en-1-one against Trypanosoma cruzi.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 15, p. 7463, doi. 10.1080/07391102.2022.2123394

By:

Cavalcante, Carlos Henrique Leitão;
Almeida-Neto, Francisco Wagner de Queiroz;
da Rocha, Matheus Nunes;
Bandeira, Paulo Nogueira;
de Menezes, Ramon Róseo Paula Pessoa Bezerra;
Paula Magalhães, Emanuel;
Sampaio, Tiago Lima;
Marinho, Emmanuel Silva;
Marinho, Márcia Machado;
Maria Costa Martins, Alice;
dos Santos, Hélcio Silva

Publication type:

Article

HIF1 inhibition of the biflavonoids against pancreas cancer: drug-likeness, bioavailability, ADMET, PASS, molecular docking, molecular dynamics, and MM/GBSA calculations.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 14, p. 6845, doi. 10.1080/07391102.2022.2112619

By:

Frota, Lucas Soares;
da Rocha, Matheus Nunes;
Bezerra, Lucas Lima;
da Fonseca, Aluísio Marques;
Marinho, Emmanuel Silva;
de Morais, Selene Maia

Publication type:

Article

Seasonal variation of the composition of essential oils from Piper cernuum Vell and Piper rivinoides Kunth, ADMET study, DFT calculations, molecular docking and dynamics studies of major components as potent inhibitors of the heterodimer methyltransferase complex NSP16-NSP10 SARS COV-2 protein

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 13, p. 6326, doi. 10.1080/07391102.2022.2107072

By:

Alves Borges Leal, Antonio Linkoln;
Fonseca Bezerra, Camila;
Ferreira e Silva, Andressa Kelly;
Everson da Silva, Luiz;
Bezerra, Lucas Lima;
Almeida-Neto, Francisco Wagner;
Marinho, Emanuelle Machado;
Celedonio Fernandes, Carla Freire;
Nunes da Rocha, Matheus;
Marinho, Marcia Machado;
Coutinho, Henrique D. M.;
Barreto, Humberto Medeiros;
Rafaela Freitas Dotto, Ana;
Amaral, Wanderlei do;
Santos, Hélcio Silva dos;
Lima-Neto, Pedro de;
Marinho, Emmanuel Silva

Publication type:

Article

Hypoglycemic and hepatoprotective effects in adult zebrafish (Danio rerio) of fisetinidol isolated from Bauhinia pentandra: In vivo and in silico assays.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 6, p. 2274, doi. 10.1080/07391102.2022.2029771

By:

da Silva, Horlando Carlota;
Monteiro, Aurelio de Oliveira;
Almeida-Neto, Francisco Wagner de Queiroz;
Marinho, Emanuelle Machado;
Ferreira, Maria Kueirislene Amâncio;
Mendes, Francisco Rogênio da Silva;
Marinho, Emmanuel Silva;
Marinho, Márcia Machado;
Bezerra, Lucas Lima;
da Rocha, Matheus Nunes;
de Menezes, Jane Eire Silva Alencar;
Teixeira, Alexandre Magno Rodrigues;
da Silva, Antonio Wlisses;
Rebouças, Emanuela de Lima;
Pinto, Francisco das Chagas Lima;
dos Santos, Hélcio Silva;
Pinheiro Santiago, Gilvandete Maria

Publication type:

Article

Diterpene Sonderianin isolated from Croton blanchetianus exhibits acetylcholinesterase inhibitory action and anxiolytic effect in adult zebrafish (Danio rerio) by 5-HT system.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 24, p. 13625, doi. 10.1080/07391102.2021.1991477

By:

Lima, Joyce dos Reis;
Ferreira, Maria Kueirislene Amancio;
Sales, Ketelly Vanessa Barros;
da Silva, Antônio Wlisses;
Marinho, Emanuelle Machado;
Magalhães, Francisco Ernani Alves;
Marinho, Emmanuel Silva;
Marinho, Márcia Machado;
da Rocha, Matheus Nunes;
Bandeira, Paulo Nogueira;
Teixeira, Alexandre Magno Rodrigues;
de Menezes, Jane Eire Silva Alencar;
dos Santos, Hélcio Silva

Publication type:

Article

Chemical Composition and Larvicidal Activity Against Aedes aegypti of the Leaf Essential Oils from Croton blanchetianus.

Published in:

Molecules, 2025, v. 30, n. 5, p. 1034, doi. 10.3390/molecules30051034

By:

Lopes, Pedro Henrique Ribeiro;
Pereira, Nicaely Maria de Oliveira;
da Rocha, Matheus Nunes;
Marinho, Marcia Machado;
Guedes, Jesyka Macêdo;
Rodrigues, Tigressa Helena Soares;
Do Vale, Jean Parcelli Costa;
Marinho, Emmanuel Silva;
Santiago, Gilvandete Maria Pinheiro;
Santos, Hélcio Silva dos

Publication type:

Article